CS197323B2 - Coated supporting material for the chromatography on the thin layer with the concentrating zone - Google Patents

Coated supporting material for the chromatography on the thin layer with the concentrating zone Download PDF

Info

Publication number: CS197323B2
Authority: CS; Czechoslovakia
Prior art keywords: layer; concentration zone; chromatography; silica; concentration
Prior art date: 1977-05-31

Application number

CS783432A

Other languages

Czech (cs)

English (en)

Inventor

Herbert Halpaap

Karl-Friedrich Krebs

Hans Heinz

Original Assignee

Merck Patent Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1977-05-31

Filing date

1978-05-26

Publication date

1980-04-30

1978-05-26 Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh

1980-04-30 Publication of CS197323B2 publication Critical patent/CS197323B2/cs

Links

239000000463 material Substances 0.000 title claims description 16
238000004587 chromatography analysis Methods 0.000 title abstract description 14
VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims abstract description 73
239000011148 porous material Substances 0.000 claims abstract description 31
239000000377 silicon dioxide Substances 0.000 claims abstract description 24
238000004809 thin layer chromatography Methods 0.000 claims description 14
238000011144 upstream manufacturing Methods 0.000 claims description 4
239000002245 particle Substances 0.000 claims description 3
235000012239 silicon dioxide Nutrition 0.000 abstract description 2
239000000243 solution Substances 0.000 description 19
238000000576 coating method Methods 0.000 description 16
239000000741 silica gel Substances 0.000 description 16
229910002027 silica gel Inorganic materials 0.000 description 16
239000000126 substance Substances 0.000 description 16
239000011248 coating agent Substances 0.000 description 15
YXFVVABEGXRONW-UHFFFAOYSA-N Toluene Chemical compound CC1=CC=CC=C1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 description 12
238000001035 drying Methods 0.000 description 11
238000011161 development Methods 0.000 description 10
239000000725 suspension Substances 0.000 description 10
239000000975 dye Substances 0.000 description 8
239000011888 foil Substances 0.000 description 8
239000000203 mixture Substances 0.000 description 7
238000000926 separation method Methods 0.000 description 7
HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 6
239000012876 carrier material Substances 0.000 description 6
238000003756 stirring Methods 0.000 description 6
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 6
239000011230 binding agent Substances 0.000 description 5
230000008021 deposition Effects 0.000 description 5
230000000694 effects Effects 0.000 description 5
239000002594 sorbent Substances 0.000 description 5
238000001179 sorption measurement Methods 0.000 description 5
238000012360 testing method Methods 0.000 description 5
229910052782 aluminium Inorganic materials 0.000 description 4
XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 4
239000003480 eluent Substances 0.000 description 4
239000011521 glass Substances 0.000 description 4
UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 description 3
OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 3
229940024606 amino acid Drugs 0.000 description 3
150000001413 amino acids Chemical class 0.000 description 3
230000002349 favourable effect Effects 0.000 description 3
229910052748 manganese Inorganic materials 0.000 description 3
239000011572 manganese Substances 0.000 description 3
-1 manganese-activated zinc silicate Chemical class 0.000 description 3
238000000034 method Methods 0.000 description 3
238000002360 preparation method Methods 0.000 description 3
150000003839 salts Chemical class 0.000 description 3
HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 description 2
ROHFNLRQFUQHCH-YFKPBYRVSA-N L-leucine Chemical compound CC(C)C[C@H](N)C(O)=O ROHFNLRQFUQHCH-YFKPBYRVSA-N 0.000 description 2
KZSNJWFQEVHDMF-UHFFFAOYSA-N Valine Chemical compound CC(C)C(N)C(O)=O KZSNJWFQEVHDMF-UHFFFAOYSA-N 0.000 description 2
239000013543 active substance Substances 0.000 description 2
239000001045 blue dye Substances 0.000 description 2
239000001913 cellulose Substances 0.000 description 2
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235000010980 cellulose Nutrition 0.000 description 2
239000003795 chemical substances by application Substances 0.000 description 2
239000010949 copper Substances 0.000 description 2
238000007598 dipping method Methods 0.000 description 2
238000000605 extraction Methods 0.000 description 2
230000007935 neutral effect Effects 0.000 description 2
239000004033 plastic Substances 0.000 description 2
229920003023 plastic Polymers 0.000 description 2
229920001495 poly(sodium acrylate) polymer Polymers 0.000 description 2
BDERNNFJNOPAEC-UHFFFAOYSA-N propan-1-ol Chemical compound CCCO BDERNNFJNOPAEC-UHFFFAOYSA-N 0.000 description 2
238000000746 purification Methods 0.000 description 2
238000009738 saturating Methods 0.000 description 2
NNMHYFLPFNGQFZ-UHFFFAOYSA-M sodium polyacrylate Chemical compound [Na+].[O-]C(=O)C=C NNMHYFLPFNGQFZ-UHFFFAOYSA-M 0.000 description 2
239000002904 solvent Substances 0.000 description 2
210000002700 urine Anatomy 0.000 description 2
AZUYLZMQTIKGSC-UHFFFAOYSA-N 1-[6-[4-(5-chloro-6-methyl-1H-indazol-4-yl)-5-methyl-3-(1-methylindazol-5-yl)pyrazol-1-yl]-2-azaspiro[3.3]heptan-2-yl]prop-2-en-1-one Chemical compound ClC=1C(=C2C=NNC2=CC=1C)C=1C(=NN(C=1C)C1CC2(CN(C2)C(C=C)=O)C1)C=1C=C2C=NN(C2=CC=1)C AZUYLZMQTIKGSC-UHFFFAOYSA-N 0.000 description 1
XKZQKPRCPNGNFR-UHFFFAOYSA-N 2-(3-hydroxyphenyl)phenol Chemical compound OC1=CC=CC(C=2C(=CC=CC=2)O)=C1 XKZQKPRCPNGNFR-UHFFFAOYSA-N 0.000 description 1
OMCVXIQHMVXMNN-DFWYDOINSA-N 2-aminoacetic acid;(2s)-2,5-diamino-5-oxopentanoic acid Chemical compound NCC(O)=O.OC(=O)[C@@H](N)CCC(N)=O OMCVXIQHMVXMNN-DFWYDOINSA-N 0.000 description 1
PBCKVROHSSNSDY-UHFFFAOYSA-N 2-methylprop-2-enoic acid;sodium Chemical compound [Na].CC(=C)C(O)=O PBCKVROHSSNSDY-UHFFFAOYSA-N 0.000 description 1
RZVAJINKPMORJF-UHFFFAOYSA-N Acetaminophen Chemical compound CC(=O)NC1=CC=C(O)C=C1 RZVAJINKPMORJF-UHFFFAOYSA-N 0.000 description 1
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239000004475 Arginine Substances 0.000 description 1
238000004438 BET method Methods 0.000 description 1
241000167854 Bourreria succulenta Species 0.000 description 1
229910052684 Cerium Inorganic materials 0.000 description 1
VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 description 1
RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 description 1
XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 1
239000005909 Kieselgur Substances 0.000 description 1
QNAYBMKLOCPYGJ-REOHCLBHSA-N L-alanine Chemical compound C[C@H](N)C(O)=O QNAYBMKLOCPYGJ-REOHCLBHSA-N 0.000 description 1
239000004395 L-leucine Substances 0.000 description 1
235000019454 L-leucine Nutrition 0.000 description 1
AYFVYJQAPQTCCC-GBXIJSLDSA-N L-threonine Chemical compound C[C@@H](O)[C@H](N)C(O)=O AYFVYJQAPQTCCC-GBXIJSLDSA-N 0.000 description 1
PWHULOQIROXLJO-UHFFFAOYSA-N Manganese Chemical compound [Mn] PWHULOQIROXLJO-UHFFFAOYSA-N 0.000 description 1
229920000168 Microcrystalline cellulose Polymers 0.000 description 1
NHNBFGGVMKEFGY-UHFFFAOYSA-N Nitrate Chemical compound [O-][N+]([O-])=O NHNBFGGVMKEFGY-UHFFFAOYSA-N 0.000 description 1
239000004952 Polyamide Substances 0.000 description 1
QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 description 1
AYFVYJQAPQTCCC-UHFFFAOYSA-N Threonine Natural products CC(O)C(N)C(O)=O AYFVYJQAPQTCCC-UHFFFAOYSA-N 0.000 description 1
239000004110 Zinc silicate Substances 0.000 description 1
238000005299 abrasion Methods 0.000 description 1
238000010521 absorption reaction Methods 0.000 description 1
DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 description 1
239000011149 active material Substances 0.000 description 1
239000000654 additive Substances 0.000 description 1
QWCKQJZIFLGMSD-UHFFFAOYSA-N alpha-aminobutyric acid Chemical compound CCC(N)C(O)=O QWCKQJZIFLGMSD-UHFFFAOYSA-N 0.000 description 1
238000004458 analytical method Methods 0.000 description 1
238000000137 annealing Methods 0.000 description 1
PYKYMHQGRFAEBM-UHFFFAOYSA-N anthraquinone Natural products CCC(=O)c1c(O)c2C(=O)C3C(C=CC=C3O)C(=O)c2cc1CC(=O)OC PYKYMHQGRFAEBM-UHFFFAOYSA-N 0.000 description 1
150000004056 anthraquinones Chemical class 0.000 description 1
239000007864 aqueous solution Substances 0.000 description 1
ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 description 1
239000013060 biological fluid Substances 0.000 description 1
210000001124 body fluid Anatomy 0.000 description 1
239000010839 body fluid Substances 0.000 description 1
239000012267 brine Substances 0.000 description 1
239000001768 carboxy methyl cellulose Substances 0.000 description 1
230000015556 catabolic process Effects 0.000 description 1
GWXLDORMOJMVQZ-UHFFFAOYSA-N cerium Chemical compound [Ce] GWXLDORMOJMVQZ-UHFFFAOYSA-N 0.000 description 1
235000019693 cherries Nutrition 0.000 description 1
238000013375 chromatographic separation Methods 0.000 description 1
239000006103 coloring component Substances 0.000 description 1
238000004440 column chromatography Methods 0.000 description 1
229910052802 copper Inorganic materials 0.000 description 1
230000007423 decrease Effects 0.000 description 1
230000003247 decreasing effect Effects 0.000 description 1
238000007872 degassing Methods 0.000 description 1
238000006731 degradation reaction Methods 0.000 description 1
230000001419 dependent effect Effects 0.000 description 1
238000001514 detection method Methods 0.000 description 1
IJKVHSBPTUYDLN-UHFFFAOYSA-N dihydroxy(oxo)silane Chemical compound O[Si](O)=O IJKVHSBPTUYDLN-UHFFFAOYSA-N 0.000 description 1
ZUOUZKKEUPVFJK-UHFFFAOYSA-N diphenyl Chemical class C1=CC=CC=C1C1=CC=CC=C1 ZUOUZKKEUPVFJK-UHFFFAOYSA-N 0.000 description 1
238000004090 dissolution Methods 0.000 description 1
ZOIVSVWBENBHNT-UHFFFAOYSA-N dizinc;silicate Chemical compound [Zn+2].[Zn+2].[O-][Si]([O-])([O-])[O-] ZOIVSVWBENBHNT-UHFFFAOYSA-N 0.000 description 1
238000011156 evaluation Methods 0.000 description 1
239000012530 fluid Substances 0.000 description 1
239000003269 fluorescent indicator Substances 0.000 description 1
238000010438 heat treatment Methods 0.000 description 1
229910001385 heavy metal Inorganic materials 0.000 description 1
238000007654 immersion Methods 0.000 description 1
239000012535 impurity Substances 0.000 description 1
230000002427 irreversible effect Effects 0.000 description 1
229960003136 leucine Drugs 0.000 description 1
239000007788 liquid Substances 0.000 description 1
239000000391 magnesium silicate Substances 0.000 description 1
235000012243 magnesium silicates Nutrition 0.000 description 1
QSHDDOUJBYECFT-UHFFFAOYSA-N mercury Chemical compound [Hg] QSHDDOUJBYECFT-UHFFFAOYSA-N 0.000 description 1
229910052753 mercury Inorganic materials 0.000 description 1
239000002207 metabolite Substances 0.000 description 1
235000019813 microcrystalline cellulose Nutrition 0.000 description 1
239000008108 microcrystalline cellulose Substances 0.000 description 1
229940016286 microcrystalline cellulose Drugs 0.000 description 1
238000002156 mixing Methods 0.000 description 1
229930014626 natural product Natural products 0.000 description 1
FEMOMIGRRWSMCU-UHFFFAOYSA-N ninhydrin Chemical compound C1=CC=C2C(=O)C(O)(O)C(=O)C2=C1 FEMOMIGRRWSMCU-UHFFFAOYSA-N 0.000 description 1
239000002985 plastic film Substances 0.000 description 1
229920006255 plastic film Polymers 0.000 description 1
229920002647 polyamide Polymers 0.000 description 1
238000012545 processing Methods 0.000 description 1
238000003908 quality control method Methods 0.000 description 1
235000019812 sodium carboxymethyl cellulose Nutrition 0.000 description 1
229920001027 sodium carboxymethylcellulose Polymers 0.000 description 1
HPALAKNZSZLMCH-UHFFFAOYSA-M sodium;chloride;hydrate Chemical compound O.[Na+].[Cl-] HPALAKNZSZLMCH-UHFFFAOYSA-M 0.000 description 1
239000011877 solvent mixture Substances 0.000 description 1
241000894007 species Species 0.000 description 1
239000007921 spray Substances 0.000 description 1
239000007858 starting material Substances 0.000 description 1
229910021653 sulphate ion Inorganic materials 0.000 description 1
JBQYATWDVHIOAR-UHFFFAOYSA-N tellanylidenegermanium Chemical compound [Te]=[Ge] JBQYATWDVHIOAR-UHFFFAOYSA-N 0.000 description 1
238000005406 washing Methods 0.000 description 1
235000019352 zinc silicate Nutrition 0.000 description 1

Classifications

- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/02—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising inorganic material
- B01J20/10—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising inorganic material comprising silica or silicate
- B01J20/103—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising inorganic material comprising silica or silicate comprising silica
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
- B01J20/28014—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their form
- B01J20/2803—Sorbents comprising a binder, e.g. for forming aggregated, agglomerated or granulated products
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
- B01J20/28054—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their surface properties or porosity
- B01J20/28057—Surface area, e.g. B.E.T specific surface area
- B01J20/28059—Surface area, e.g. B.E.T specific surface area being less than 100 m2/g
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
- B01J20/28054—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their surface properties or porosity
- B01J20/28069—Pore volume, e.g. total pore volume, mesopore volume, micropore volume
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
- B01J20/28054—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their surface properties or porosity
- B01J20/28078—Pore diameter
- B01J20/28085—Pore diameter being more than 50 nm, i.e. macropores
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/30—Processes for preparing, regenerating, or reactivating
- B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
- B01J20/3202—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the carrier, support or substrate used for impregnation or coating
- B01J20/3204—Inorganic carriers, supports or substrates
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/30—Processes for preparing, regenerating, or reactivating
- B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
- B01J20/3202—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the carrier, support or substrate used for impregnation or coating
- B01J20/3206—Organic carriers, supports or substrates
- B01J20/3208—Polymeric carriers, supports or substrates
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/30—Processes for preparing, regenerating, or reactivating
- B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
- B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
- B01J20/3234—Inorganic material layers
- B01J20/3236—Inorganic material layers containing metal, other than zeolites, e.g. oxides, hydroxides, sulphides or salts
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/90—Plate chromatography, e.g. thin layer or paper chromatography
- G01N30/92—Construction of the plate
- G01N30/93—Application of the sorbent layer
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2220/00—Aspects relating to sorbent materials
- B01J2220/40—Aspects relating to the composition of sorbent or filter aid materials
- B01J2220/49—Materials comprising an indicator, e.g. colour indicator, pH-indicator
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2220/00—Aspects relating to sorbent materials
- B01J2220/50—Aspects relating to the use of sorbent or filter aid materials
- B01J2220/54—Sorbents specially adapted for analytical or investigative chromatography

Landscapes

Chemical & Material Sciences (AREA)
Analytical Chemistry (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Inorganic Chemistry (AREA)
Health & Medical Sciences (AREA)
Physics & Mathematics (AREA)
Life Sciences & Earth Sciences (AREA)
Biochemistry (AREA)
General Health & Medical Sciences (AREA)
General Physics & Mathematics (AREA)
Immunology (AREA)
Pathology (AREA)
Nanotechnology (AREA)
Engineering & Computer Science (AREA)
Solid-Sorbent Or Filter-Aiding Compositions (AREA)
Treatment Of Liquids With Adsorbents In General (AREA)
Silicon Compounds (AREA)

CS783432A 1977-05-31 1978-05-26 Coated supporting material for the chromatography on the thin layer with the concentrating zone CS197323B2 (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE2724569A DE2724569C2 (de)	1977-05-31	1977-05-31	Beschichtete Trägermaterialien für die Dünnschichtchromatographie mit Konzentrierungszone

Publications (1)

Publication Number	Publication Date
CS197323B2 true CS197323B2 (en)	1980-04-30

Family

ID=6010324

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CS783432A CS197323B2 (en)	1977-05-31	1978-05-26	Coated supporting material for the chromatography on the thin layer with the concentrating zone

Country Status (8)

Country	Link
US (1)	US4158626A (de)
JP (1)	JPS53149393A (de)
CH (1)	CH640145A5 (de)
CS (1)	CS197323B2 (de)
DE (1)	DE2724569C2 (de)
FR (1)	FR2392699A1 (de)
GB (1)	GB1596800A (de)
NL (1)	NL7805946A (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4348286A (en) *	1981-07-17	1982-09-07	Analtech, Incorporated	Large sample thin layer chromatography
FR2510758A1 (fr)	1981-07-30	1983-02-04	Oreal	Procede de prelevement et d'analyse par chromatographie sur plaque et dispositifs permettant sa mise en oeuvre
JP3749941B2 (ja) *	1997-09-04	2006-03-01	独立行政法人産業技術総合研究所	セシウム分離材の製造方法
JP6118271B2 (ja) *	2012-02-03	2017-04-19	株式会社ダイセル	クロマトグラフ媒体
JP7109194B2 (ja)	2018-01-15	2022-07-29	三菱重工パワー環境ソリューション株式会社	電気集塵装置
CN112512695B (zh)	2018-08-01	2023-08-11	三菱重工动力环保有限公司	电集尘装置
JP2024509892A (ja) *	2021-03-08	2024-03-05	ユニヴァーシティオブワシントン	単一細胞およびマイクロサンプルの分析のためのピコスケール薄層クロマトグラフィー

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NL288991A (de) *	1962-06-09
DE1792083A1 (de) *	1968-07-19	1971-04-29	Merck Anlagen Gmbh	Zweischichtenplatte und ihre Verwendung zur duennschichtchromatographischen Auftrennung von Aminosaeuren

1977
- 1977-05-31 DE DE2724569A patent/DE2724569C2/de not_active Expired
1978
- 1978-05-23 GB GB21385/78A patent/GB1596800A/en not_active Expired
- 1978-05-25 US US05/909,591 patent/US4158626A/en not_active Expired - Lifetime
- 1978-05-26 CS CS783432A patent/CS197323B2/cs unknown
- 1978-05-26 FR FR7815728A patent/FR2392699A1/fr active Granted
- 1978-05-31 CH CH595978A patent/CH640145A5/de not_active IP Right Cessation
- 1978-05-31 JP JP6445678A patent/JPS53149393A/ja active Granted
- 1978-05-31 NL NL7805946A patent/NL7805946A/xx not_active Application Discontinuation

Also Published As

Publication number	Publication date
FR2392699B1 (de)	1983-04-08
GB1596800A (en)	1981-08-26
NL7805946A (nl)	1978-12-04
FR2392699A1 (fr)	1978-12-29
JPS575461B2 (de)	1982-01-30
DE2724569A1 (de)	1978-12-14
DE2724569C2 (de)	1982-09-16
US4158626A (en)	1979-06-19
CH640145A5 (de)	1983-12-30
JPS53149393A (en)	1978-12-26

Publication	Publication Date	Title
Wall	2007	Thin-layer chromatography: a modern practical approach
Touchstone	1992	Practice of thin layer chromatography
JP5941405B2 (ja)	2016-06-29	薄層クロマトグラフィーによる試料の検出方法、薄層クロマトグラフィープレート、及びその製造方法
CH662062A5 (de)	1987-09-15	Verfahren und vorrichtung zur trennung einer oder mehrerer in loesung befindlicher verbindungen mit hilfe einer dynamischen saeulen-fluessigkeitschromatographie.
CS197323B2 (en)	1980-04-30	Coated supporting material for the chromatography on the thin layer with the concentrating zone
Halpaap et al.	1977	Thin-layer chromatographic and high-performance thin-layer chromatographic ready-for-use preparations with concentrating zones
STOLMAN	2013	Thin layer chromatography application in toxicology
Wilson et al.	1981	Reversed-phase thin-layer chromatography for the separation and analysis of ecdysteroids
JP2660558B2 (ja)	1997-10-08	精製グアヤク脂およびその製造法
US4064041A (en)	1977-12-20	Separating material for thin layer chromatography
JPH0159545B2 (de)	1989-12-18
Lewis et al.	1984	Factors affecting the ion-pair reversed-phase thin-layer chromatogrphy of organic acids on paraffin-coated and C18 bonded silica gel
US3455818A (en)	1969-07-15	Chromatographic process
JPS6310785B2 (de)	1988-03-09
DE2826664C2 (de)	1987-01-15	Verfahren zur Bestimmung von polycyclischen aromatischen Kohlenwasserstoffen
Mohammad et al.	1999	Migration behavior of aromatic amines on alumina thin layers developed with water‐in‐oil microemulsion
JPWO2013005642A1 (ja)	2015-02-23	スポット検出用セット、スポット検出方法、及び被転写シート
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Stahl et al.	1980	pH Gradient Layers for the TLC of Fluorescent Dyes
Różyło et al.	2001	Technical problems with the application of solutes to chromatographic plates in TLC
SU161753A1 (de)
Singh	2002	Chromatography
US4272380A (en)	1981-06-09	Solvent front detection method and manufacture
SU1196772A1 (ru)	1985-12-07	Способ определени фоксима в секционном материале
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