CS210191A3 - Application of flupirtin active component for the elimination of muscular overstress - Google Patents

Application of flupirtin active component for the elimination of muscular overstress

Info

Publication number
CS210191A3
CS210191A3 CS912101A CS210191A CS210191A3 CS 210191 A3 CS210191 A3 CS 210191A3 CS 912101 A CS912101 A CS 912101A CS 210191 A CS210191 A CS 210191A CS 210191 A3 CS210191 A3 CS 210191A3
Authority
CS
Czechoslovakia
Prior art keywords
flupirtin
overstress
muscular
elimination
application
Prior art date
Application number
CS912101A
Other languages
English (en)
Inventor
Michael Dr Lobisch
Ralph Dr Venhaus
Bernd Dr Nickel
Istvan Prof Szelenyi
Juergen Prof Engel
Peter Dr Emig
Original Assignee
Asta Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asta Pharma Ag filed Critical Asta Pharma Ag
Publication of CS210191A3 publication Critical patent/CS210191A3/cs
Publication of CZ280879B6 publication Critical patent/CZ280879B6/cs

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyrrole Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Golf Clubs (AREA)
  • Details Of Television Scanning (AREA)
  • Paints Or Removers (AREA)
CS912101A 1990-07-14 1991-07-08 Použití účinné látky flupirtinu pro odstranení svalového přepětí CZ280879B6 (cs)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4022442 1990-07-14
IN421CA1991 IN172468B (cs) 1990-07-14 1991-06-04

Publications (2)

Publication Number Publication Date
CS210191A3 true CS210191A3 (en) 1992-02-19
CZ280879B6 CZ280879B6 (cs) 1996-04-17

Family

ID=25895002

Country Status (30)

Country Link
US (2) US5162346A (cs)
EP (2) EP0659410B1 (cs)
KR (1) KR0182811B1 (cs)
CN (1) CN1070700C (cs)
AT (2) ATE206919T1 (cs)
AU (1) AU634073B2 (cs)
CA (1) CA2046943C (cs)
CZ (1) CZ280879B6 (cs)
DE (3) DE59109222D1 (cs)
DK (2) DK0467164T3 (cs)
EG (1) EG19814A (cs)
ES (2) ES2082887T3 (cs)
GR (1) GR3019179T3 (cs)
HR (1) HRP920667B1 (cs)
HU (1) HU206973B (cs)
IE (1) IE74688B1 (cs)
IL (1) IL98810A (cs)
IN (1) IN172468B (cs)
LT (1) LT3593B (cs)
LV (1) LV10048B (cs)
MC (1) MC2272A1 (cs)
MX (1) MX9100160A (cs)
NO (1) NO912758L (cs)
NZ (1) NZ238940A (cs)
PT (1) PT98291B (cs)
RO (1) RO108220B1 (cs)
RU (1) RU2070408C1 (cs)
SI (1) SI9111227B (cs)
SK (1) SK279567B6 (cs)
ZA (1) ZA915466B (cs)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2111659T3 (es) * 1992-03-11 1998-03-16 Asta Medica Ag Comprimidos, granulados y nodulos con alto contenido en sustancias activas para formas de administracion solidas de alta concentracion.
DE4319649A1 (de) * 1993-03-18 1994-09-22 Asta Medica Ag Feste Flupirtin enthaltende orale Darreichungsformen mit kontrollierter Wirkstoffabgabe
DE4327516A1 (de) * 1993-08-17 1995-02-23 Asta Medica Ag Primäre und sekundäre neuroprotektive Wirkung bei neurodegenerativen Erkrankungen von Flupirtin
GB9426079D0 (en) * 1994-12-23 1995-02-22 Orion Yhtymae Oy A gelatine capsule
DE19541405A1 (de) * 1995-11-07 1997-05-15 Asta Medica Ag Verwendung von Flupirtin zur Prophylaxe und Therapie von Erkrankungen, die mit einer Beeinträchtigung des hämatopoetischen Zellsystems einhergehen
US6284794B1 (en) 1996-11-05 2001-09-04 Head Explorer Aps Method for treating tension-type headache with inhibitors of nitric oxide and nitric oxide synthase
US6610324B2 (en) * 1999-04-07 2003-08-26 The Mclean Hospital Corporation Flupirtine in the treatment of fibromyalgia and related conditions
PL354484A1 (pl) * 1999-08-03 2004-01-26 Awd Pharma Gmbh & Co.Kg Zastosowanie flupirtyny do łagodzenia bólu związanego z chorobami zwyrodnieniowymi stawów u psów i kotów
US6821995B1 (en) 1999-12-01 2004-11-23 Duke University Method of treating batten disease
US20040122090A1 (en) * 2001-12-07 2004-06-24 Lipton Stuart A. Methods for treating neuropsychiatric disorders with nmda receptor antagonists
RU2213565C1 (ru) * 2002-06-24 2003-10-10 Общество с ограниченной ответственностью "Паркинфарм" Способ лечебного воздействия на организм пациента при лечении болезни паркинсона
DE10255415A1 (de) * 2002-11-28 2004-06-09 Bayer Healthcare Ag Dermale Applikation von Flupirtin
DE10327674A1 (de) * 2003-06-20 2005-01-05 Awd.Pharma Gmbh & Co. Kg Injizierbare Darreichungsform von Flupirtin
US7799832B2 (en) 2003-10-23 2010-09-21 Valeant Pharmaceuticals North America Combinations of retigabine and sodium channel inhibitors or sodium channel-influencing active compounds for treating pains
DE102004001558A1 (de) * 2004-01-10 2005-08-18 Bayer Healthcare Ag Arzneimittel zur topischen Applikation bei Tieren
US20050196461A1 (en) * 2004-01-14 2005-09-08 Udell Ronald G. Ceramide formulations suitable for oral administration
EP1715843A1 (en) * 2004-01-29 2006-11-02 Neuromolecular Inc. Combination of a nmda receptor antagonist and a mao-inhibitor or a gadph-inhibitor for the treatment of central nervous system-related conditions
US20050220862A1 (en) * 2004-03-31 2005-10-06 Bernstein Joel E Compositions with reduced hepatotoxicity
US7619007B2 (en) * 2004-11-23 2009-11-17 Adamas Pharmaceuticals, Inc. Method and composition for administering an NMDA receptor antagonist to a subject
EP1688141A1 (en) * 2005-01-31 2006-08-09 elbion AG The use of flupirtine for the treatment of overactive bladder and associated diseases, and for the treatment of irritable bowel syndrome
EP2243475B1 (en) 2005-04-06 2016-01-13 Adamas Pharmaceuticals, Inc. Combination of memantine and donepezil for treatment of CNS disorders
JP2009535370A (ja) * 2006-05-02 2009-10-01 クリス ルントフェルト ジストニアおよびジストニア様症状の予防および治療におけるカリウムチャンネル活性剤
US7960436B2 (en) * 2006-06-05 2011-06-14 Valeant Pharmaceuticals International Substituted arylamino-1,2,3,4-tetrahydro naphthalenes and-2,3-dihydro-1H-indenes as potassium channel modulators
WO2008024398A2 (en) * 2006-08-23 2008-02-28 Valeant Pharmaceuticals International Derivatives of 4-(n-azacycloalkyl) anilides as potassium channel modulators
US8993593B2 (en) * 2006-08-23 2015-03-31 Valeant Pharmaceuticals International N-(4-(6-fluoro-3,4-dihydroisoquinolin-2(1H)-yl)-2,6-dimethylphenyl)-3,3-dimethylbutanamide as potassium channel modulators
US8722929B2 (en) * 2006-10-10 2014-05-13 Valeant Pharmaceuticals International N-[2-amino-4-(phenylmethoxy)phenyl] amides and related compounds as potassium channel modulators
BRPI0719590A2 (pt) * 2006-11-28 2014-01-21 Valeant Pharmaceuticals Int Análogos de retigabina 1,4 diamino bicíclica como modulares de canal de potássio
US20080279930A1 (en) * 2007-05-07 2008-11-13 Bernd Terhaag Controlled-Release Flupirtine Compositions, Compacts, Kits and Methods of Making and Use Thereof
US8367684B2 (en) * 2007-06-13 2013-02-05 Valeant Pharmaceuticals International Derivatives of 4-(N-azacycloalkyl) anilides as potassium channel modulators
AR070513A1 (es) * 2007-08-01 2010-04-14 Lundbeck & Co As H Uso de abridores de canales de potasio kcnq para reducir los sintomas o tratar desordenes o afecciones en las cuales se encuentra anulado el sis-tema dopaminergico como por ejemplo esquizofrenia y trastorno depresivo mayor
US8563566B2 (en) * 2007-08-01 2013-10-22 Valeant Pharmaceuticals International Naphthyridine derivatives as potassium channel modulators
US7786146B2 (en) * 2007-08-13 2010-08-31 Valeant Pharmaceuticals International Derivatives of 5-amino-4,6-disubstituted indole and 5-amino-4,6-disubstituted indoline as potassium channel modulators
ES2347119B2 (es) * 2009-04-22 2011-04-28 Universidad De Santiago De Compostela Nanocapsulas de poliarginina.
DE102010030053A1 (de) 2010-06-14 2011-12-15 Awd.Pharma Gmbh & Co.Kg Injizierbare Darreichungsform von Flupirtin
JP6251667B2 (ja) * 2014-06-03 2017-12-20 アサヒカルピスウェルネス株式会社 錠剤型即放性製剤及びその製造方法
DE102017007385A1 (de) 2017-08-02 2019-02-07 Christoph Hoock Maleatfreie feste Arzneimittelformen
TWI886158B (zh) 2019-10-10 2025-06-11 加拿大商再諾製藥公司 選擇性鉀通道調節劑之固態晶型
GEP20257732B (en) 2019-11-08 2025-02-10 Xenon Pharmaceuticals Inc Methods of treating depressive disorders
KR20240004241A (ko) 2021-02-09 2024-01-11 제논 파마슈티칼스 인크. 무쾌감증의 치료에 사용하기 위한 전압-게이트 칼륨 채널 오프너

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1795858C2 (de) 1968-07-19 1979-01-11 Deutsche Gold- Und Silber-Scheideanstalt Vormals Roessler, 6000 Frankfurt Benzylaminopyridine
DE3133519A1 (de) 1980-09-13 1982-06-09 Degussa Ag, 6000 Frankfurt "2-amino-3-carbethoxyamino-6-(p-fluor-benzylamino)-pyridin-maleat"
DE3665538D1 (en) * 1985-01-23 1989-10-19 Asta Pharma Ag Synergistic combination of flupirtin and non-steroidal anti-phlogistics
ATE43789T1 (de) * 1985-02-23 1989-06-15 Asta Pharma Ag Kombination von flupirtin und anticholinergisch wirkenden spasmolytika.
DE3604575A1 (de) * 1985-02-23 1986-08-28 Degussa Ag, 6000 Frankfurt Kombination von flupirtin und anticholinergisch wirkenden spasmolytika
FI855016A7 (fi) * 1985-06-28 1986-12-29 Degussa Flupirtiinin ja 4-asetamido-fenolin synergistinen yhdistelmä.

Also Published As

Publication number Publication date
LV10048B (en) 1995-06-20
EP0467164B1 (de) 1996-01-31
DK0659410T3 (da) 2001-12-27
LT3593B (en) 1995-12-27
RO108220B1 (ro) 1994-03-31
EP0659410A3 (de) 1995-10-25
MX9100160A (es) 1992-02-28
EP0659410B1 (de) 2001-10-17
NO912758D0 (no) 1991-07-12
HUT59313A (en) 1992-05-28
HU912359D0 (en) 1991-12-30
ES2082887T3 (es) 1996-04-01
IL98810A (en) 1996-01-19
SI9111227A (en) 1995-06-30
US5162346A (en) 1992-11-10
DE4122166A1 (de) 1992-01-16
NZ238940A (en) 1997-05-26
DK0467164T3 (da) 1996-03-04
PT98291B (pt) 1999-01-29
DE59107331D1 (de) 1996-03-14
AU634073B2 (en) 1993-02-11
HU206973B (en) 1993-03-01
MC2272A1 (fr) 1993-06-23
CZ280879B6 (cs) 1996-04-17
HRP920667A2 (en) 1996-10-31
CN1070700C (zh) 2001-09-12
LTIP919A (en) 1995-03-27
US5284861A (en) 1994-02-08
CN1058716A (zh) 1992-02-19
EP0467164A2 (de) 1992-01-22
KR920002147A (ko) 1992-02-28
IN172468B (cs) 1993-08-14
AU8040391A (en) 1992-01-16
ES2164111T3 (es) 2002-02-16
EP0467164A3 (en) 1992-04-15
SI9111227B (sl) 2000-12-31
IL98810A0 (en) 1992-07-15
HRP920667B1 (en) 1998-06-30
SK279567B6 (sk) 1999-01-11
CA2046943C (en) 1996-03-12
ATE133564T1 (de) 1996-02-15
PT98291A (pt) 1992-05-29
LV10048A (lv) 1994-05-10
ZA915466B (en) 1992-04-29
GR3019179T3 (en) 1996-06-30
CA2046943A1 (en) 1992-01-15
KR0182811B1 (ko) 1999-05-01
IE912451A1 (en) 1992-01-15
NO912758L (no) 1992-01-15
EP0659410A2 (de) 1995-06-28
IE74688B1 (en) 1997-07-30
DE59109222D1 (de) 2001-11-22
ATE206919T1 (de) 2001-11-15
RU2070408C1 (ru) 1996-12-20
EG19814A (en) 1996-02-29

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Legal Events

Date Code Title Description
IF00 In force as of 2000-06-30 in czech republic
MK4A Patent expired

Effective date: 20110708