CS251923B1

CS251923B1 - Process for producing reagent paper

Info

Publication number: CS251923B1
Application number: CS34683A
Authority: CS
Inventors: Vera M Ostrovskaja; Ludmila V Lomakina; Nikolaj A Fomin; Marija C Aksenova; Olga N Gariceva; Alexandr V Ivascenko; Vladimir P Mamajev; Viktor P Krivopalov; Igor G Gach
Original assignee: Vera M Ostrovskaja; Ludmila V Lomakina; Nikolaj A Fomin; Marija C Aksenova; Olga N Gariceva; Ivaschenko Alexandr V; Vladimir P Mamajev; Viktor P Krivopalov; Igor G Gach
Priority date: 1981-07-10
Filing date: 1983-01-19
Publication date: 1987-08-13
Also published as: SU1178819A1; CS34682A1

Abstract

Způsob získání reagenčního papíru, zahrnuje zpracování modifikovaného chromatografíckého papíru na základě monoaldehydcelulozy heterilhydrnzinem a potom diazotovaným arylamldem v rozpouštědle. Podle vynálezu jako rozpoučtědlo se používá směs dlmetylformamidu a vodního tlumicího roztoku s pH 5 až 6,6 při jejich poměru L : 0,4 až 10·The method of obtaining reagent paper includes treating modified chromatography paper based on monoaldehyde cellulose with heterylhydrin and then diazotized arylamide in a solvent. According to the invention, a mixture of dimethylformamide and an aqueous buffer solution with a pH of 5 to 6.6 at their ratio L : 0.4 to 10 is used as the solvent.

Description

AND

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HeflocTaTKOM cnocoCa nonyqeHHH peaKTHBHoft CynarH ΗΒΠΗβτοπ ncnonbao-BaHHe HflOBHTOro h floporocTOHtnero nupHAHHa on cTajQHH o6pa6oTKH BynarH / meat * THpOBaHHblM 3MHH0M, i TO ιΟόΠΟΜΗΗβΤ yCHOBHH OCpaCOTKH CyMarH! HeoCXOHHMOCTbTmaTenbHoN repMeTH3aijHH annapaTypbi, orpaHHqeHne yBennqeHHH MacmTaCa aarpys-kh b npoMbimneHHbix ycnoBHHx, noBbnneHHe ctohmocth npoflyxTa.

HanConee 6jih3Khm to onHCbiBaeMOMy HSoCpeTeHioo no TexHHqecKoň cyntHocTH hflocTHraewoMy pe3ynbTaTy HBnneTCH cnoco6 no-nyttemvt peaKTKBaoň CyMarH nyTeMoCpaCoTKH MOflH (t> HimpoBaHHOfl χρΟΜβτοΓρβφΜΗβεκοή CyMarH Ha οοηοβθ MOHoanbflerHfl-Ρθτηιιοηο3μ reTepjtnrnnpa3HHOM 4-MeTHn-6-OKCH-2-nHpHMHnHnrHflpa3HHa (2-rnnpa3H-HO-6 ~ MeTH, n-4 (3H) -nHpaMtWHHOH), and 33τβΜ αη33ΟΤηροββηηημ apHiiaMHHOM b cpepeBOfbl H nHpHmma (2).

He / jocTaTKOM 3τογο cnocoGa nonyneHHJi peaKTHBHoft 6yMarH «bjihctch Hcnojibao-Bahn nupHflHHa - ηαοβητογο (κροβηηοΑ ha) h b noporocTOHinero pacTBopHTeJiH co-jwniecTBe 2 κγ hh 1 κγ GyMarH, HTO ocJiOMHneT ycjiOBHH nojiyneHHH GyMarH. KpoMetoto, peaKTHBHan GyMara, nojiyueHHaH well flaHHOMy cnocoGy, HMeeT HenpiiHTHbift3anax HHpHflHHa, ηπΗ yztaneHUH κοτοροΓΟ HeoGxoflHMa οτμμβκη peaKTHBHoft GyMarH «Ba / waTHKpaTHbíMH no Becy KOjiHnecTBaMH boam, aueTona h EE h oTanona fljiHTejib-hon cymKH.

Uenbio n3o6peTeHHB hbjibstcb ynpomeHHe cnocoCa nojiyneHHH peaKTHBHoft GyMarH. YKa3aHHaH ijejib flocTHraeTCB τβΜ, ητο b cnocoGe nojiyMeHiw peaKTHBHoft GyMa- f γη rivet o6pa6oTKH ΜΟΑΗφΗΐΐΗροΒβΗΗοή xpoMaTorpatfrHnecKoň GyMarH Ha ocHOBe Mo-HoanbflernRuejLnjono3bi reTepnnriwpa3HHOM and 3aTeM αη33οτηροβ8ηημμ aMHHOM b-CPE Ae pacTBopHTenB cornacno Η3θ6ρβτβΗΗΐο b xanecTBe pacTBopHTejia Hcnojib3y »TCMecb ΠΗΜβΤΗπφορΜβΜΗηβ η βοαηογο 6y <J> epHoro parTBOpa c pH 5-6.5 npH hx coot-HomeHHH εοοτΒβτοτΒβΗΗο 1: 0.4-10. ΠρΗΜβΗβΗΗβ nranb βοαηογο 6y <J> epHoro pacTBopa 6ea ΑΗΜβΤΗπφορΜβΜΗΑβ He npn-βοαητ κ o6pa3OBaHHK> peaKTHBHoft GyMara. ΠρΗ pH <5 χροΜβτοΓρβφΗΗβοκβΗ GyMaraBO3BpaqaeTca H3 peaKAHOHHoro pacTBopa He η3μθηθηηοΑ, npH pH> 7 HfleT pa3Jio-weHHe AHa3ocoenHHeHHH, and GyMara noKpbroaeTca cMOJiononoGHbMH oTjioweHHHMH.

HcnoJibsoBaHHe npefljiaraeMoro cnocoGa noaponneT noJiynHTb peaxTHBHyio GynaryBMCOKOrO KaHeCTBa NPH HCKJItOHeHHH ΗΑΟΒΗΤΟΓΟ H nopOrOCTOHmero paCTBOpHTenH., NojrynaeMaa well 3T0My cnocoGy peaKTHBHan GyMara ΗΜβετ paBHOMepHyw oKpacxy 1 BnHTHBaeMOCTb He HHwe 30 mm / MHH, Ile HMeeT 3anaxa and well ΜβτβπηοΗΗΑΗκβτορΗΜΜ, ιHOHcejieKTHBHbíM η κβτΗΟΗΗΟοβΜβΗΗΗΜ cBoňcTBaM He ycTynaeT peaKTHBHoft GyMare, nonyneHHoft H3BecTHbiM cnocoGoM. IIpeftnaraeMMn cnocoG nojiyneHHH peaKTHBHoft GyMarH ηβαηθτοη τηποβμμ, toecTb πρΗΓΟβΗΜΜ απη nojiyneHHH raHpoKoro achopTHMeHTa peaKTHBHbix GyMar. ΠρΗΜβρ 1. nojiyneHHe peaKTHBHoft GyMarH Ha ocHOBe 1 (5) -φβΗηπ- (4-ΗβτΑΑ-6-OKCH-2-nHpHMHnHH-2Hn) β OpMa 3 α -H-6-α 1 JW) J103bI. 700 Γ ΜΟΛΗφΗΙΙΗρΟΒβΗΗΟΗ ΧρΟΜβτάΓρβφΗΜΘΟΚΟβ GyMarH OCHOBe MOHoanbflerHfl IIa-c flejimonosbi coflepmaHHeM anbflerHflHbix rpynn 0.35 μγ-3Κβ / γ 3ajiHBaioT 42 r-2-tHflpa3HHO 4 "ΜΘΤΗΠ-6" B OKCHnHpHMHflHHa CMeCH 12 JI 2.5% -ΗΟΓΟ pacTBopa yKCyCHOfl ·· 'KHcnoTbi 0.4 h η φοεφβτΗΟΓΟ 6yφepHOΓO C, pH 7, 3 Ha ocTaBJísioT Maca, οτΦηαβτ-'pOBbiBaioT (φππΒτρβτ rHHpa3HHa HcnojibsywT EME flBaawbi απη oGpaGoTKH hobhx GyMarn NAP-THN) 3anHBaioT npn 0-2® pacTBopoM, coctohiuhm H3 αη33οτηροβ3ηηογο70 r aHHjiHHa 8 αημθτιίπΦορμ3μηα3 3.8 apeTaTHoro it 6yφepHOΓO pacTBopa CPH 5.5-6 Ha 0.5 NACA. ByMary οτφίυΐΒτροΒΜΒβιοτ, npoMbiBawT flHCTHJuiHpoBaHHOň BO-3 floft Pasa 3TaHOJiOM hjih aneTOHOM, cymaT. flojiyneHHaH peaKTHBHaa GyMara HMeeTκορΗΗΗβΒβτο- «eJiTbiň ηΒβτ h ó6pa3yeT c ηοηθμη MeflH npH pH-3-9 KOMnjiexc KpacHO-φHOJIeτoBOΓo ιχΒβτβ. flaHHaa peaKTHBHaa G yMara no3B0JiaeT onpenejiHTb Meflb c npe-nejiaMH oGHapynceHHH 0,01 μγ / ji - 2 μγ / ji CT 0,15 μγ / θκβ / γ. ΠρΗΜβρ 2. nojiyyeHHe peaKTHBHoft GyMarH Ha ocHOBe 1-φβΗΐιπ-5- (4-α-6-οκ-ch-2-πηρημηληπ) ^ opMa3aH-6-nejunoji03bi.

PeaKTHBHyio GyMary nojiynaioT xax b npHMepe paCTBOpOM flHa3OCOeflHHeHHH e CMeCH 10 JI φΟβφβΤΗΟΓΟ βνφερΗΟΓΟ pacTBO-pa 0.5 naca, πρκ TeMnepaType - 2-0 ° C.nojiynaioT peaKTHBHyio GyMary what CTaTHaecKoň eMKOCTbio no MeflH 0.1 μγ-3κβ / γ. Πρiyβρ 3. nojiyneHne peaKTHBHÓň GyMarH Ha ocHOBe 1 (5) - (2-thiocarboxylic acid) - (4-MeTHJI-6-OKCHnHpHMHflHH-2-HJl) -OpMa3aH-6-fleflJII0JIO3bl.

PeaKTHBHyio GyMary nojiynatoT xaK b npHMepe (P 1 c τβΜ οτπΗΗΗβΜ, hto bmcctoflHaaorapOBaHHOrHHJIHHa HCnOJJb3yjOT flHa3OTHpOBaHHblft ορτο-3HH3HflHH. NOJiyneH- 251923 - 3 -

Hyflo peaKTHBHaa OyMara ΗΜββτ opaHxeBbiň ηβθτ h oOpaayeT.c hohsmh κηπμηη npnpH 5 "9-ΤβΜΗΟ θορΗΟΒΟβ ΟΚρβΠΙΗΒβΗΗβ, Μβ" Η ΚΟρΗΗΗβΒβΤΟ-φΗΟΗβΤΟΒΟβ, pTyTH Η ΠβίΓjia «HH cepoBaroe, ηηκθπη .κορΗΗΗβΒβτο-opaHxeBoe OKpamtBaHHe, ηηηκη - cnaOyionpHHBeTKy. KaflMuň moxho onpenejiflTb b Anana3OHe 0.05-500 μγ / ji c noMombW hbh-Ηοϋ SyMarn b npucyrcTBHH ΙΟ-κρβτΗωχ κοπΗΗβετΒ ηηηκβ η ΗΗκβηπ, and Meflb mbckh — pyeTCfl THOMoneBHHoň. "ΠρΗΜβρ 4 * nojiyneHne peaKTHBHoň OyMarn Ha ocHOBe 1 (5) -φβΗΗπ (4,6-πΗΜβτοκ-chhhphahh-2-χηπ) -φορΜβ 3 an-6-6-uenniano 3bi. . PeaKTHBHyro OyŇary nonynaroT κβκ b npHMepe 1 c τβΜ οτπΗΗΗβΜ ,. ητο ΒΜβετο2-ρΑρβ3ΗΗΟ-4 · τΜβΤΗΗ-6-ΗΠΗρΗΜΗΗΗΗβ HCnOJIbSyiOT 2-ΓΗΗρβ9ΗΗΟ-4,6 ~ ΗΗΜβΤΟΚΟΗΠΗ "PHMHhhh. PeaKTHBHaa OyMara Πθ3ΒΟΗΗβΤOnpenejIHTb MeHb Β npHCyTCTBHH ΤβΚΗΧ ΗΟΗΟΒ ΜβΤβΠΠΟΒ, ΚβΚ ΕβΠΟΗΗΜβ, ΠΧβΠΟΜΗΟ-aeMeflbHbie, peflKoaeMenbHhie, Tflxenbie, nepexoflHbie h flpyrHe (b TOM HHcne ρτγτπ, HHHK, HHKejib, cepeOpo). ΠρΗΜβρ fifth nojiyneHne peaKTHBHoň OyMara Ha ocHoee 1 (5) -φβΗΗη- (4--βΤΗη-6-MeTOKCHnHpHMHflHH-2-HJi) —φθρΜβ33Η — 6 “HeflJII0JIO3M ·

PeaKTHBHyro 6yMary nonynaiOT Kax npHMepe IP b 1 c τθμ othhhhsm, HTO Hcnonb 3ywT-2-rHflpaaHHO ΜβΤΗΠ-4-6-MeTOKCupHMHflHH »ĚeaKTHBHafl OyMara ΗΜββτ« h ejrryroOKpacKy ceneKTHBHo oOpaayeT NPH pH 2,5-9 c hohhmh μθαη κοΜπηβκο τθμηο-φΗΟΗβΤΟΒΟΓΟ 2βΤβ ΟΟΟΗΗΠΗβΤ ΟΠρβ2βΠΗΤΒ 0.02 /γ / π - 500 Mr / π pβΛΗ Β npHCyT-CTBHH 100-KpaTHt> ix KOHHHecTB pryTH, ΗΗΚβΗΗ, HHHKa, cépeOpa. ΠρκΜβρ 6. IlojTyHeHHe peaKTHBHoň CyMarH Ha ocHOBe 1 (5) -φβΗΗπ (4-φβΗΗΠΠΗρΗ-MHWHH-2-nn) ~ φθρΜβ33Η— 6-Ι | β JHBOJ10 3W, '

PeaKTHBHyro 6ywary nonynaroT κβκ b npHMepe IP 1, ho Hcnonb3y »T 2-rHHpa 3 HHO-4-φβκΗππΗρΗΜΗΛΗΗ. PeaKTHBHaa OyMpra ΗΜββτ xenTyro OKpacxy, ac ηοηημη nennnpn pH 1,5 o0pa3yeT κοΜπηβκσ cepo-geneHO ΗΒβτβ. 'ΠρΗΜβρ 7. ΠΟΗΥΗβΗΗβ peaKTHBHoň.OyMaΓΗ Ha ΟΟΗΟΒβ 1, (5) -φβΗΗΠ (ΠΗρΗΜΗΗΗΗ- 2-ΚΠ) -φορ -β 3 and H-6-no JIJ1KH10 3Μ.

PeaKTHBHyro OyMary nonynaroT κβκ β 'npHMepe IP 1c τβΜ οτπΗΗΗβΜ, ητο Hcnonb-WyTOT 2-ΓΗ, ΠΡ33ΗΗΟΠΗρΗΜΗΗΗΗ.

PeaKTHBHafl OyMara enββτ xenTyro OKpacKy h OOpaayeT κοΜπηβκο npn pH 1.5 cMeflbw cHpeHeBoro Ήθβτβ, and npn pH 6 c hhhkom opaMtcesoro ΗΒβτβ, c ΗπκβηβΜΡΟ30ΒΟΓΟ Ι | ΒβΤ3, C ΧβΗβ3ΟΜ. ΠρΗΜβρ 8. nonyueHHe peaKTHBHoň OyMara Ha ocHOBe 1 (5) -φβΗπ (4-βτΗΠ-Π fl-pHMH £ flH-2-Hn) -φθρΜ83 and H-6-εejtr <n U UIO3M.

PeaKTHBHyro 0yMary nonynatoT κβκ b npHMepe IP 1 c τβτ οτπηηηθμ, hto hc-nOHbSyiOT 2-ΓΗηρ83ΗΗΟ-4 “ΜβΤΗΠΠΗρΗΜΗΗΗΗ. PeaKTHBHafl OyMara ejββτ ejβΤ, h oOpaayeT κοΜπηβκο c Meflbto npn pH> 1.5 CHpeHeBoro ΗΒβτβ, πρκ pH 5 - φκο-neTOBoro HBeTa, πρκ pH> 2 what pTyTbio opaHxeBoro useTa, npH pH 5 c ΗπκβηβΜΡΟ3ΟΒΟΓΟ — CHpeHeBoro HBeTa, c xene3OM ( ) Τ τ τ c c O O O O 6 6 6 6 6 6 n n n n n n n n n n M M M M M M M ony ony ony ony ony ony -6-Ηβ JUIKinO3M.

PeaKTHBHyw OyMary nonynaroT RaK b npHMepe IP I c Μ ο μ 3, ητο Hcnojib-aywT 2-rH «pa3HH0-4-0KcHnHpHMHHHH (2-ΗΗΟβ3ΗΗΟ-4 (3Η) -ΠΗρΗΜΗΠΗΗΟΗ). PeaKTHBHaflOyMara ΗΜββτ xenTyro OKpacKy h o0pa3yeT, κοΜπηβκβΜ npH pH> 1,5 c Megbro -ρκο-ΟΗρβΗβ, npn pH 5 C HβΛΒΤΟΜ ΚΟΟρΚΟΟβ, ΠρΗ pH> 6 ΚΟρΗΗΗβΒΟΓΟΗΒβΤΗ, Η ΚβΛΜΗΗ ΛΜΗΗρβΗΧβΒΟΓΟ ΗΒβΤβ. 251923 - of, - npHMep 10. nouyueHHe peaKTHBHoň CyMarH to ocHoue I (5) -φβΗΗπ-2 (2 ~ οκεκφε-ΗΗΠ) -6-φβΗΗΠΠΗρΗΜΗΛΗΗ-4 ~ ΗΠ-φθρΜ33 and »-6“ UeUUroUO3bI.

PeaKTHBHyro CyMary nouyuaiOT κβκ b npHMepe fp 1 c τβΜ οτπηηηθμ, uc Hcnoub-ayJOT Hfl 1 CTaflHH 4-ΗΗΟρ33ΗΗΟ-2- (2-ΗΗφβΗΗπ) -5-φθΗΗΠΠΗρΗΜΗΗΗΗ. PeaKTHBHaHCyMara M θ M eu eu eu eu eu eu OR p p asy asy asy asy asy c c c c c c c c c c c c c c c c c c c π c c T T T T T T T b b b b b b b b b b b b b b Πρyβρ 11. nouyueHHe peaKTHBHoň CyMarH Ha οοηοβθ 1 (5) -φε.- (5-Cp.OMnH-PHMHflHH-2-HJI) -φορΜβ 3 and H-6-UeonionO3bI.

PeaKTHBHyro 6yMary nonyuaroT κβκ b npnMepe IP 1 c τβΜ otuhuhcm, uc Hcnoub-ayioT Ha 1 cthuhh 2-rHa pa3HHO-5-GpoMnnpnMHflHH.

PeaKTHBHaH CyMara HMeeT ateuTyw ÓKpacKy h oCpasyeT KOMnuercbi πρπ pH? 1,5c Mejabio CHHero βχ, ρρκ pH> 1 c uauauneMueueueoroorooroorooroaaa n n, npw pH ^ 3 coPTyTbio BρπΗΗΗο-κορΗΗΗβΒΟΓΟ UBeTa, πρκ pH 5 c Ko6anbTOM ceporo UBeTa, c »euesoM (II) UBeTa.

IlpHMep · 12. nouyueHHe peaKTHBHoň OyMarn Ha οοηοβθ 1 (5) -Φθηηβ-4- (4-μετοκ-ΟΜφβΗΗΠ JnHpHMHUHH-2 — Ηπ) φθρΜ833Η — 6 — UenjTI0J103bl,

PeaKTHBHyro CyMary nouyuaroT Kar b npHMepe IP 1 c those OTUHUHeM, u Hcnoub-3yiOT Ha 1 CTaUHH 2-ΓΗηρΗ3ΗΗΟ-4- (4-ΜΘΤσΚεΗφ6ΗΗη) -ΠΗρΗΜΗΗΗΗ. PHMaTaBeHeMeTaTe xyToOkPacKyH oCpa3yeT roMnuercbi npn pH> 1.5c Meubio θ — U U U U U π>>>>>>>>> T T T T T c KOCanbTOM CemeBoro uneTo, cEo3OM (II) co ~ uBeTa. "ΠρΗΜβρ 13. NouyueHHe peaKTHBHoň CyMarn Ha ochobc 1 (5) -φβΗΗη-4- (2-ΗκεΗφε-ΗΗπ) -6-φβΗΗΠΐΐΗρΗΜΗΠΗΗ-2-Ηπ) -φσρΜ33 and H-6-UeUJBOUO 3bl.

PeaKTHBHyro. CyMary nouyuaroT Kar b npHMepe IP 1 c θ μ u,,,, CT CT CT CT Ha CTaUHH 2-ρβρ33ρ-4- (2-ΟΚεΗφθΗΗη) - · 6-φθΗΗηΠΗρΗΜΗΑΗΗ.

PH> 1.5c Meubro cepo-aeueHoro uBeTa, npu pH> 2 Co pTyTbio opamceBero UBeTa. ΠρΗΜβρ 14. nouyueHHe peaKTHBHoň CyMarH Ha ocHoee 1 (5) -φβΗΗη- (5--εΗΗη-πηρημηληη-2-ηπ) - $ opMa3aH-6-ueunrono3bi ..

PeaKTHBHyro CyMary nouyuaroT κβκ b npHMepe IP 1 c τημηηημμ, uc Hcnouh-3yroT Ha 1 cTauHH 2-rHUpa 3 HHO-5 ^HHJinHpHMHUHH. PeaKTHBHaH CyMara HMeeTcBeTuo-xeuTyiO p p ac h pa pa pa pa pa pa pa pa pa pH>>>>>>>>>>>>>>>pH> 1.5 c aeueHoro UBeTa, c uhhkom KopHUHeBoroUBeTa, c HHKeueM εβρο-φKοηετοΒΟΓΟ uBeTa. ΠρΗΜβρ 15. nouyueHHe peaKTHBHoň CyMarH Ha ocHOBe 1 (5) -φβΗΗη-4- (2-οκοΗ-φβΗΗΠ) —PΗρΗΜΗβΗΗ-6 — HJI — φθρΜ333Η-6-UIJI10nO3bI.

PeaKTHBHyro CyMary nouyuaroT Kar b npHMepe ÍP 1 c Μ ο η η η η to to, hcnoub-3yiOT Ha. neBO CTaflHH 6 ~ ΓΗΑρ33ΗΗ0-4 “(2-ΗΗφβΗΗη)“ ΠΗρΗΜΗ, ΑΗΗ .. PeaKTHBHaH Cy- (Mara ημθθτ aceUTyro KKpacKy h oCpasyeT κομππθκ πμκ pH πρκ pH> 1,5 c Méflbio τθμηο-'cHHero UBeTa, πρκ pH> 1 c nauuaflHeM 3eueHoro UBeTa, πρκ pH> 2 co.pTyTbio · KpacHOBaTO — KOpHUHeBoro UBeTa, πρκ pH> 4 c KOCanbTOM cepo-KopKUHorte UBeTa, npH ρΗϊ- 5 c uhhkom KpacHO — κορΗΗΗβΒΟΓο UBeTa, c HHKeueM κορημηθβητο — cHpeHe — Boro “UBeTa, c M ue OM II II M M M M M M M M M M M M M M M M M M M M M M M M 3 3 3 3 3 3 3 3 3 “3ορΜβ 3 and H-6-UeUUIOUO 3 b !.

PeaKTHBHyro CyMary nouyuaroT khk b npHMepe IP 1 c θ η η to c c c c c c c c c c c 3 3 3 3 3 3 3 3 3 3 3. PeaKTHBHaH Cy-251923

Mara ΗΜββτ xtejiTyw OKpacKy h o6pa3yeT κομππθκομ npw pH? 1.5 c Mepbro θ 1cnHero ρΒβτβ, πρκ pH> 1 c .nanjiauH M 3eHoro ueeTa, npH pH> 2 what pTyTbwKpacHOBaTO-KopmiHeBoro ρΒβτβ, npH pH> 4c Ko6anbTOM κορηηηθβογο ueeTa, npHpH> 5c Kejie3OM (II) KopHHHeBoro peeTa. 17. nojryneHHe peaKTHBHoň OyMarH Ha ocHOBe 1 (5) -φβΗκπ [2- (2-οκοηΦθ-ηηπ) -πηρημηρηη-4-ηπ)] -φορΜβ3αH-6-yennwno3bi.

PeaKTHBHyw CyMary nonynawT κ κ n n ep Í ep ep ep 1 1 c c c c c c c c c c c 1 1 c c c c c c c c c c c π π π π π π π π π. PeaKTHBHaH CyMara.ΗΜββτ HcejiTywf OKpacKy h oSpaayeT KOMnneKcw πρκ pH> 1.5 c Mepbw φΗοπβτοΒΟΓοUBeTa, and pH pH> 5 τβΜΗθ-CHHero peeTa, npH pH? 1 c nannapneM aejieHoro uee-Ta, npn pH> 2 c pTyTbw oparacesoro ρΒβτβ, πρκ pH> 4 c COCANBTOM KopHHHeBÓroUBeTa, Πρβρβη oGHapyxeHHH MeflH 0.01-1 μγ / η. 18. nonytteHHe peaKTHBHoň SyMarn Ha ocHoee 1 (5) -φβΗΗΐι [2- ^ 6-xjiop- 3,4-HHMeran-1Ηππροηηηη [3,4-b] nHpa3on-1-κπ ^ 5-3τηπ-6-μθτηππηρημη, αηη- 2-ηπ> ρορ-M83αH-6-uenntóno3ω.

PeaKTHBHyw SyMary nonynawT kbk b npHMepe IP 1 c τβΜ οτπΗΗΗβΜ, hto Ha non-CTaUHH HCnOJIb3ytOT 6-XJIOp-1 (4-rHflpa3HHO-5-3THn-6-MeTHnnHpHMHflHH-2-Hn) - 3.4- UHMeTJtn-1H-nHpasono ( 3,4-b) πηρηρηη. PeaKTHBHaH CyMara ΗΜββτ xejrry »oKpac-Ky, npn pH 2-7 o6pa3yeT what pTyTbw κοΜηπεκε cepo-φΗθπβτοΒθΓο ρβετβ, κοτορωΑpaapymaeTCfl πρκ peňcTBHH 0.1 η cojihhoA khcjiotm. PeaKUHH no οτηοιπθηημ κ ρτγ-th cejieKTHBHa, PeaKTHBHaH CyMara He ACCOUNT flBeTHbix peaKUHň c qenoHHbtMH, methyl ΠΟΗΗΟ-aeMeubHbíMH, peuKoaeMenbHbíMH Me 'anjiaMH, uhhkom, κβρΜΗβΜ, ΗΗΚβηβΜ, Xena-3ΟΜ (III) CJia6o Η3ΜβΗβΗΗΘ OKpaCKH ΠρΗ B3aHMOfleňCTBHH C ΧβΠβ3ΟΜ (II) Η KO-CanbTOM. ΠρΗ pH 2,5-7 o6pa3yeTcMenbio κοΜππεκε aeneHOBaTO-ceporo ρΒβτβ. PH> 1 c nannaflHeM o6paayeT cepoBaTO — KopHUHeBoro ρββτβ. C noMombw paHoPeKTHBHo ySyMarn bosmoxho onpepeneHHe pTyTH b «HanasoHe 20-500, μγ / ji npocTMMnorpyxeHHeM SyMarn b pacTBOp h 0,1-10 μg / π c noMonp> w KapMaHHoro HHUHKaTopHo — ro ycTpoftcTBa. ΠρΗΜβρ 19. tiojiyweHHe peaKTHBHoň CyMarH Ha ocHoee 1 (5) -φβΗκπ [2- [5-κβκ-CHJI-I (2,4) HI, 2,4-TpHα3OJI-2-HnJ βΜΗΗΟ-5-3ΤΗΠ-6-ΜβΤΗΠΠΗρΗΜΗΛΗΗ -2-Ηπ | -φθρΜβ3βΗ-6- * UeJ11J10nO3b !.

PeaKTHBHyw 6yMary nonyuawT κβκ b npHMepe IP 1 c Μ ο η Ha nep au au au au au au au au au au au au au au au au au au au au au r au Η-1,2,4-TpHa3on.

PeaKTHBHaH CyMara oCpaayeT what pTyTbw πρκ pH 2-7 ComNKC 3eneHOBaTo-rofly-6oro UBeTa, c Mepbw s'πρκ pH 2,5-7 aeneHOBaTo-ceporo ρΒβτβ, πρκpH> 1 c · najuiauneM This is the H3MenEnHe ρο'οττβΗκβ Oex, e HHKeneM 'h, xeneaoM (III) HeB3aHMoniteTByeT. C noMomhw paHHOft peaKTHBHoň 6yMarn bo9moxho onpepeneHHepTyra b uHanaaoHe 0,1-500 μγ / π, ΠρΗΜβρ 20 nojryneHHe peaKTHBHoň SyMarn Ha ocHOBe 1 (5) -φβΗΗΠ- (4-ΗβτΠΠ-6-οκεΗ-2-ηΗρΗΜΗβΗπ) uejiraono3bi.

PeaKTHBHyw 6yMary nonynw n κ ep ep τ ep ep 1 1 1 1 1 1 1 1 1 π π π π π π π π π π π π π π π π π π π π π π π π π π π π π π π π π π π π π π π π. CooTHomeHHe ρΗΜβτΗπφορΜβΜΗρβh 6yφepHOΓ pacTBOpa cocTaBnaeT 1: 0.4. nonyuawT peaKTHBHyw 6yMary what ctbth — qecKoň o ^ MenHoň eMKocTb »no MepH 0.15 μγ / 3Κβ / γ. 21. NonyneHne 2- η 4-γηρρ83ηηοπηρημηληηοβ. A6maa Μβτορκκβ cHHTe-3a: 2- cooTBeTCTBywnpífl ηπη χπορπηρημηρηη 4-h-rHppasHH RNPP κηπητητ b cnnp-Te η / ηΠΗ UHOKCaHe B ΤβΗβΗΗβ HeCKOflbKHX Hacoba PO ΗΟΗβ3ΗΟΒβΗΗΗ HCXOflHOrO xnop-ΠΗΡΗΜΗΒ, ΗΗΒ (KOHTpOUb OCyHeCTBPHWT TOHKOCHÓňHOň ΧρΟΜβΤΟΓρβφΗβΑ Ha οΗπγφοπβ 251923-6 - UV -254). PacTBopHTSJíb οτγοηβμτ b BaKyyne, ocanox οτφκπΒτροΒΗΒβιοτ, npoMbiBaioTlBOflOn h cymaT. IIonynaioT γηπρ33μηοπηρημηιιηημ c βηχοπομ> 90 ^.

Hušce npHBeflejtw nonyneHHbie 2- n 4-γηπρ33ηηοπηρημηπηηη, hx TeMnepaTypannaBJíeHHH (τ.ππ.) h flaHHbie ajieweHTHoro aHanH3a: 4-THflpa3HHO-2- (2-OKCH $ eHHn) -6 “$ eHHJinHpHMHnHH, Τ.ΠΠ. 134-137 [deg.] (H3 cnupT-BOfla). BhiHHCJieHO, X: C 69.06, H 5.04, N 20.14, C 16 H 14 N 4 O H aq H 1, X: C 69.12, H 5.10, N 20.02. 2-rHflpa3HHO-4- (4-MeClkIlHKn) nHpnMHHHH, τ.ππ. 138.5-140 (n3 crotpTa).

BbiuHCJieHo ,. X: C 61.09, H 5.59, N 25.91. Cu H, 4N40.

Hefleho, X: C 61.15, H 5.63, N 25.84. 2-riropa3HHO-5-ηθηηππμρμμηπμη, τ.ππ. 160-162 (h3 cnHpTa). H, 5.41; N, 30.09. H, 5.30; N, 30.21. 4-rHxipa3HHO-6- (2-ocphenol) iiHpHMHflHH τnn255-228 ° (cnupTxmoKcaH). X, C 59.04, H 5.08, N 27.25, C 0 H 6 ON, O 4. H, E, H, C 59.39, H 4.98, N 27 * 71. 2-rHflpa3HHO-4- (2-OKCH <beHKn) -6- (t) eHH1HpHMHf1HH, τ.ππ. 201-203 °, no nnTepa-TypHblM flaHHblM Τ.ΠΠ. 202 °. 2-nitro-4H-4- (2-olefinic acid), as follows, τ.ππ. 217-219 °. X, C 59.39, ,98 4.98, N 27.71. CwH10N4O. H, H, X: C 59.43, H 5.00, N 27.30.

HacTonmnft cnoco6 πο3Βθππετ ynpocTHTb nponecc nonyneHna peaKTHBHoň CyMarHfHCKrnoMHTb Hcnonb3OBaHHe ηποβητογο paCTBOpHTenn h nonynHTb 6yMary xopomeroKanecTBa.

ΦΟΡΜΥΗΑ H30BPETEHHB

Cnoco6 nonyneHun peaKTHBHoň SyMarn, BKnwnaiomHň oCpaCoTxy ΜΟΑΗφΗΐχκροΒβΗ-hon χροΜβτοΓρβφΗπεοκοή ČyMarn Ha ocHone MOHoanbnermwenniono3bi reTepnJirnnpa-3HHOM and 3aTeM nna3OTHpOBaiIHbIM apitnaMHHOM B cPen paCTBOpHTenn, OTHHMaiOmHft -CN τβΜ, πτο c uenbio ynpomeHHn npoyecca b xanecTBe pacTBopuTenn Hcnonb3y »TCMeCb ΑΗΜβΊΉπφορΜΘΜΗΠβ Η ΒΟβΗΟΓΟ θνφβρΗΟΓΟ pacTBOpa C pH 5 “6.5 npH HX COOT” 1: 0.4-10. HCTOWHHKH ΗΗφορΜβΠΗΗ, ΠρΗΗΗΤΗβ BO ΒΗΗΜ3ΗΗΘ ΠρΗ 3ΚΟΠερΤΗ3β; 1. AsTopcicoe cBHneTenbCTBO CCCP 59 '592905, κπ. D 21 Η 3/02, 1976. 2. Αθτορεκοε cBHfleTenbCTBO CCCP 11 '1116777 - προτοτΗΠ. Α Η Η 0 Α Α Π Η Η θ3θ6ρετεΗΗβ othochtch κ oSnacTH yennrono3HO-6yMaXHoň προμμπιπθηηοοτη.

Henb ο3ο6ρετεΗΗ «- ynpomeHne npoijecca.

Cnoco6 nonyneHHH peaKTHBHoň SyMarn BiunonaeT o6pa6oTKý ΜοπκφΗΐίΗροΒβΗΗΟϋχρθΜ3τθΓρ3φΗπεεκοί! SyMara on MOHoanbflerHnuennrono3bi reTepHnrHflpa3HH0M.a and 33τβΜ nHa3OTHpOBaHHbiM apHnaMHHOM b cpene paCTBOpHTenn. CornacHO Η3θ6ρετε-hhjo b xanecTBe paCTBOpHTenn Hcnonb3ytoT CMecb ΠΗΜετΗπφορΜβΜΗΠβ h BOflHoro 6y ~ φερΗΟΓΟ pacTBOpa c pH 5-6,5 npn hx cooTHomeHHH οοοτβθτοτβθηηοο 1: 0,4-10. IIpH3HaHO θ3θ6ρετεΗΗβΜ fio pesynbTaTaM 3κεπερτκ3Η, ocymecTBneHo TocyflapcT-BeHHWfa CPοΜΗτετοΜ CCCP no flenaM Η3θ6ρετβΗκή η οτκρΜΤκή. 251923 '

Claims

OBJECT OF THE INVENTION A method for producing reagent paper, comprising treating the modified paper paper based on monoaldehyde hydoelulose with a phthalylhydrazine followed by diazotized arylamine in a solvent, characterized in that a mixture of dimethylformamide and aqueous buffer is used as the solvent for the process. e pH 5 aS.5.5 accepting a ratio of 1 s 0.4 a2 10, UŽgorodský výrobnž-polygrafický podnik, Pcoektnaja 4, Užgorod »3893, Price 2.40 Kcs