CS272018B1 - Ethereal derivatives of 4/3h/-quinazolinone - Google Patents

Ethereal derivatives of 4/3h/-quinazolinone Download PDF

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Publication number
CS272018B1
CS272018B1 CS887195A CS719588A CS272018B1 CS 272018 B1 CS272018 B1 CS 272018B1 CS 887195 A CS887195 A CS 887195A CS 719588 A CS719588 A CS 719588A CS 272018 B1 CS272018 B1 CS 272018B1
Authority
CS
Czechoslovakia
Prior art keywords
quinazolinone
formula
difluoro
compounds
hydrochloride
Prior art date
Application number
CS887195A
Other languages
Czech (cs)
English (en)
Other versions
CS719588A1 (en
Inventor
Ludmila Ing Csc Fisnerova
Bohumila Ing Csc Brunova
Eva Mudr Maturova
Jaroslava Mudr Csc Grimova
Original Assignee
Fisnerova Ludmila
Brunova Bohumila
Maturova Eva
Grimova Jaroslava
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fisnerova Ludmila, Brunova Bohumila, Maturova Eva, Grimova Jaroslava filed Critical Fisnerova Ludmila
Priority to CS887195A priority Critical patent/CS272018B1/cs
Priority to CA000609601A priority patent/CA1316924C/fr
Priority to EP19890116865 priority patent/EP0367944A3/fr
Priority to AU42880/89A priority patent/AU4288089A/en
Priority to JP1283147A priority patent/JPH02172977A/ja
Priority to US07/430,293 priority patent/US4973691A/en
Publication of CS719588A1 publication Critical patent/CS719588A1/cs
Publication of CS272018B1 publication Critical patent/CS272018B1/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/225—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C39/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
    • C07C39/24—Halogenated derivatives
    • C07C39/367—Halogenated derivatives polycyclic non-condensed, containing only six-membered aromatic rings as cyclic parts, e.g. halogenated poly-hydroxyphenylalkanes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/88—Oxygen atoms
    • C07D239/90—Oxygen atoms with acyclic radicals attached in position 2 or 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CS887195A 1988-11-01 1988-11-01 Ethereal derivatives of 4/3h/-quinazolinone CS272018B1 (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
CS887195A CS272018B1 (en) 1988-11-01 1988-11-01 Ethereal derivatives of 4/3h/-quinazolinone
CA000609601A CA1316924C (fr) 1988-11-01 1989-08-28 Derive ethere de 4/3h/-quinazoline et procede d'obtention
EP19890116865 EP0367944A3 (fr) 1988-11-01 1989-09-12 Dérivés éthérés de 4-[3H]-quinazolinone, procédé pour leur préparation et compositions pharmaceutiques
AU42880/89A AU4288089A (en) 1988-11-01 1989-10-13 Etheric derivative of 4/3h/-quinazoline and a process for the preparation thereof
JP1283147A JPH02172977A (ja) 1988-11-01 1989-11-01 ４（３ｈ）―キナゾリノンのエーテル誘導体およびその製法
US07/430,293 US4973691A (en) 1988-11-01 1989-11-01 Etheric derivative of 4(3H)-quinazolinone and a process for preparation thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CS887195A CS272018B1 (en) 1988-11-01 1988-11-01 Ethereal derivatives of 4/3h/-quinazolinone

Publications (2)

Publication Number Publication Date
CS719588A1 CS719588A1 (en) 1990-03-14
CS272018B1 true CS272018B1 (en) 1990-12-13

Family

ID=5420647

Family Applications (1)

Application Number Title Priority Date Filing Date
CS887195A CS272018B1 (en) 1988-11-01 1988-11-01 Ethereal derivatives of 4/3h/-quinazolinone

Country Status (6)

Country Link
US (1) US4973691A (fr)
EP (1) EP0367944A3 (fr)
JP (1) JPH02172977A (fr)
AU (1) AU4288089A (fr)
CA (1) CA1316924C (fr)
CS (1) CS272018B1 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5290780A (en) * 1991-01-30 1994-03-01 American Cyanamid Co. Angiotensin II receptor blocking 2,3,6 substituted quinazolinones
US5204354A (en) * 1992-02-14 1993-04-20 Merck & Co., Inc. Substituted quinazolinones as neurotensin antagonists useful in the treatment of CNS disorders
JP2005055674A (ja) * 2003-08-05 2005-03-03 Ricoh Co Ltd 現像マグネットローラ、現像装置、プロセスカートリッジ及び画像形成装置
TWI273911B (en) * 2005-01-18 2007-02-21 Univ Nat Chiao Tung Prevention and amelioration of acetaminophen toxicity with tea melanin

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL131479C (fr) * 1966-04-20
FR2528826A1 (fr) * 1982-06-16 1983-12-23 Sanofi Sa Nouveaux composes derives de phenols, procede de preparation desdits composes et medicaments antiseborrheiques et anti-inflammatoires contenant comme substance active au moins un desdits composes

Also Published As

Publication number Publication date
AU4288089A (en) 1990-05-10
EP0367944A2 (fr) 1990-05-16
US4973691A (en) 1990-11-27
EP0367944A3 (fr) 1990-12-05
CS719588A1 (en) 1990-03-14
CA1316924C (fr) 1993-04-27
JPH02172977A (ja) 1990-07-04

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