CS9100418A2 - Method of amino acids' optically active amides racemization - Google Patents

Method of amino acids' optically active amides racemization

Info

Publication number: CS9100418A2
Authority: CS; Czechoslovakia
Prior art keywords: amino acid; optically active; mixture; aldehyde; acid amide
Prior art date: 1990-02-16

Application number

CS91418A

Other languages

English (en)

Inventor

Wilhelmus Hubertus Jos Boesten

Original Assignee

Stamicarbon

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-02-16

Filing date

1991-02-18

Publication date

1991-09-15

1991-02-18 Application filed by Stamicarbon filed Critical Stamicarbon

1991-09-15 Publication of CS9100418A2 publication Critical patent/CS9100418A2/cs

1996-07-17 Publication of CZ281203B6 publication Critical patent/CZ281203B6/cs

Links

150000001413 amino acids Chemical class 0.000 title abstract 7
238000000034 method Methods 0.000 title abstract 3
150000001408 amides Chemical class 0.000 title 1
230000006340 racemization Effects 0.000 title 1
125000002485 formyl group Chemical class [H]C(*)=O 0.000 abstract 3
239000000203 mixture Substances 0.000 abstract 3
150000008574 D-amino acids Chemical class 0.000 abstract 2
150000008575 L-amino acids Chemical group 0.000 abstract 2
239000002262 Schiff base Substances 0.000 abstract 2
150000004753 Schiff bases Chemical class 0.000 abstract 2
150000001735 carboxylic acids Chemical class 0.000 abstract 2
150000003839 salts Chemical class 0.000 abstract 2
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 2
239000011541 reaction mixture Substances 0.000 abstract 1
239000002904 solvent Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/16—Preparation of optical isomers
- C07C231/20—Preparation of optical isomers by separation of optical isomers
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B57/00—Separation of optically-active compounds
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/20—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C249/00—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton
- C07C249/02—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton of compounds containing imino groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
- C07C319/26—Separation; Purification; Stabilisation; Use of additives
- C07C319/28—Separation; Purification

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Analytical Chemistry (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

CS91418A 1990-02-16 1991-02-18 Způsob racemizace opticky aktivních amidů aminokyselin CZ281203B6 (cs)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
NL9000386A NL9000386A (nl)	1990-02-16	1990-02-16	Werkwijze voor de bereiding van optisch aktief aminozuuramide.
SG13294A SG13294G (en)	1990-02-16	1994-01-26	Process for the preparation of an optically active amino acid amide.

Publications (2)

Publication Number	Publication Date
CS9100418A2 true CS9100418A2 (en)	1991-09-15
CZ281203B6 CZ281203B6 (cs)	1996-07-17

Family

ID=26646659

Country Status (12)

Country	Link
US (1)	US5306826A (cs)
EP (1)	EP0442584B1 (cs)
JP (1)	JP2854148B2 (cs)
KR (1)	KR0179028B1 (cs)
AT (1)	ATE97125T1 (cs)
CZ (1)	CZ281203B6 (cs)
DE (1)	DE69100598T2 (cs)
DK (1)	DK0442584T3 (cs)
ES (1)	ES2062660T3 (cs)
HU (1)	HU212703B (cs)
NL (1)	NL9000386A (cs)
SG (1)	SG13294G (cs)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5346653A (en) *	1991-02-18	1994-09-13	Matsushita Electric Industrial Co., Ltd.	Non-linear optical material, method of manufacturing the same and optical wavelength converter
NL9201230A (nl) *	1992-07-09	1994-02-01	Dsm Nv	Werkwijze voor de bereiding van optisch aktief methionineamide.
JP2701685B2 (ja) *	1992-12-28	1998-01-21	田辺製薬株式会社	光学活性４−メルカプト−２−ピロリドン誘導体及びその合成中間体の製法
US5495012A (en) *	1992-12-28	1996-02-27	Tanabe Seiyaku Co., Ltd.	Process for preparing optically active 4-mercapto-2-pyrrolidone derivative and intermediate therefor
BE1007296A3 (nl) *	1993-07-19	1995-05-09	Dsm Nv	Werkwijze voor de bereiding van een beta-lactamderivaat.
JPH08157437A (ja) *	1994-12-08	1996-06-18	Ajinomoto Co Inc	Ｄ−アミノ酸−Ｎ−（Ｓ）−α−アルキルベンジルアミドの製造法
BE1010647A3 (nl) *	1996-09-24	1998-11-03	Dsm Nv	Werkwijze voor de bereiding van een anorganisch zout van een optisch aktief fenylglycinederivaat.
SE0100902D0 (sv)	2001-03-15	2001-03-15	Astrazeneca Ab	Compounds
SE0202539D0 (sv)	2002-08-27	2002-08-27	Astrazeneca Ab	Compounds
SE0401762D0 (sv)	2004-07-05	2004-07-05	Astrazeneca Ab	Novel compounds
US7648992B2 (en)	2004-07-05	2010-01-19	Astrazeneca Ab	Hydantoin derivatives for the treatment of obstructive airway diseases
SE0403086D0 (sv)	2004-12-17	2004-12-17	Astrazeneca Ab	Compounds
SE0403085D0 (sv)	2004-12-17	2004-12-17	Astrazeneca Ab	Novel componds
TW200800954A (en) *	2006-03-16	2008-01-01	Astrazeneca Ab	Novel crystal modifications
TW200831488A (en)	2006-11-29	2008-08-01	Astrazeneca Ab	Novel compounds
CN102952029B (zh) *	2011-09-30	2015-07-08	北京海步国际医药科技发展有限公司	将苄胺衍生物用于拆分2-羟基-3-甲氧基-3,3-二-苯基丙酸消旋物及拆分方法
KR102055702B1 (ko) *	2017-12-12	2019-12-13	주식회사 아미노로직스	광학 활성을 가진 2-옥틸글리신 에스터를 제조하는 방법
CN115103836A (zh) *	2020-02-16	2022-09-23	艾雅拉制药公司	制备手性苯并二氮杂卓酮衍生物的方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
BE795874A (fr) *	1972-02-25	1973-08-23	Glaxo Lab Ltd	Procede de preparation d'esters optiquement actifs d'alpha-amino-acides
NL7514300A (nl) *	1975-12-09	1977-06-13	Stamicarbon	Werkwijze voor de bereiding van optisch actief fenylglycineamide.
US4072698A (en) *	1976-12-02	1978-02-07	The Upjohn Company	Resolution of aminonitriles
DE2749203C2 (de) *	1977-11-03	1981-12-17	Riedel-De Haen Ag, 3016 Seelze	Verfahren zur Racematspaltung von DL-alpha-Aminocarbonsäuren und diastereomere Salze
FR2430413A1 (fr) *	1978-07-07	1980-02-01	Anvar	Procede de preparation d'alpha-aminoacides optiquement actifs, et leurs derives

1990
- 1990-02-16 NL NL9000386A patent/NL9000386A/nl not_active Application Discontinuation
1991
- 1991-02-13 HU HU91482A patent/HU212703B/hu not_active IP Right Cessation
- 1991-02-13 KR KR1019910002589A patent/KR0179028B1/ko not_active Expired - Fee Related
- 1991-02-14 DE DE69100598T patent/DE69100598T2/de not_active Expired - Fee Related
- 1991-02-14 AT AT91200306T patent/ATE97125T1/de not_active IP Right Cessation
- 1991-02-14 ES ES91200306T patent/ES2062660T3/es not_active Expired - Lifetime
- 1991-02-14 DK DK91200306.8T patent/DK0442584T3/da active
- 1991-02-14 EP EP91200306A patent/EP0442584B1/en not_active Expired - Lifetime
- 1991-02-15 US US07/655,623 patent/US5306826A/en not_active Expired - Lifetime
- 1991-02-15 JP JP3022137A patent/JP2854148B2/ja not_active Expired - Fee Related
- 1991-02-18 CZ CS91418A patent/CZ281203B6/cs not_active IP Right Cessation
1994
- 1994-01-26 SG SG13294A patent/SG13294G/en unknown

Also Published As

Publication number	Publication date
CZ281203B6 (cs)	1996-07-17
DK0442584T3 (da)	1994-03-07
JPH05178805A (ja)	1993-07-20
NL9000386A (nl)	1991-09-16
SG13294G (en)	1994-06-10
ES2062660T3 (es)	1994-12-16
DE69100598T2 (de)	1994-05-19
DE69100598D1 (de)	1993-12-16
KR0179028B1 (ko)	1999-05-15
KR910021368A (ko)	1991-12-20
HUT56532A (en)	1991-09-30
JP2854148B2 (ja)	1999-02-03
EP0442584B1 (en)	1993-11-10
ATE97125T1 (de)	1993-11-15
US5306826A (en)	1994-04-26
EP0442584A1 (en)	1991-08-21
HU212703B (en)	1996-10-28
HU910482D0 (en)	1991-08-28

Legal Events

Date	Code	Title	Description
2000-06-30	IF00	In force as of 2000-06-30 in czech republic
2006-10-11	MM4A	Patent lapsed due to non-payment of fee	Effective date: 20060218

Publication	Publication Date	Title
CS9100418A2 (en)	1991-09-15	Method of amino acids' optically active amides racemization
NZ193375A (en)	1983-06-14	Peptide synthesis using carboxypeptidase enzyme
IE901673L (en)	1990-11-09	Enzymatic removal of a protein amino-terminal sequence
ATE1745T1 (de)	1982-11-15	Verfahren zur herstellung von carbonsaeureamiden und peptiden.
DE3875953D1 (de)	1992-12-17	Verfahren zur herstellung von organischen chemischen verbindungen.
DK0460883T3 (da)	1997-07-14	Fremgangsmåde til beta-hydroxy-alfa-aminosyrer
TW238297B (cs)	1995-01-11
ATE119202T1 (de)	1995-03-15	Verfahren zur herstellung von l-aminosäuren und aminosäure-amiden.
CS9100417A2 (en)	1991-09-15	Method of amino acids' optically active amides preparation
EP0294668A3 (en)	1990-07-11	(2-cyano-2-oximinoacetyl)-amino acid derivatives
DE69526462D1 (de)	2002-05-23	Verfahren zur Herstellung von Peptiden aus N-Carboxyanhydridaminosäuren
DE3887854D1 (de)	1994-03-24	Verfahren zur Herstellung von Dipeptiden.
DE68904395D1 (de)	1993-02-25	Verfahren zur synthese von 3-chlor-2,4,5-trifluorbenzoesaeure.
ATE68787T1 (de)	1991-11-15	Verfahren zur herstellung von n-acylierten mercapto-alpha-aminosaeuren.
ATE163200T1 (de)	1998-02-15	Verfahren zur herstellung von peptiden mit c- terminalem prolin-amid
ATE68175T1 (de)	1991-10-15	Verfahren zur herstellung von l,l oder d,d oder racemat n6 benzyloxycarbonyl 2,6 diaminopimelinsaeuremonoamid.