CS9100483A2 - Carbapenemic derivatives with antibiotic efficiency, method of their preparation and application - Google Patents
Carbapenemic derivatives with antibiotic efficiency, method of their preparation and applicationInfo
- Publication number
- CS9100483A2 CS9100483A2 CS91483A CS48391A CS9100483A2 CS 9100483 A2 CS9100483 A2 CS 9100483A2 CS 91483 A CS91483 A CS 91483A CS 48391 A CS48391 A CS 48391A CS 9100483 A2 CS9100483 A2 CS 9100483A2
- Authority
- CS
- Czechoslovakia
- Prior art keywords
- carbapenemic
- derivatives
- preparation
- application
- antibiotic efficiency
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
- C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
- C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
- C07D477/20—Sulfur atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP4279690 | 1990-02-23 | ||
| JP21228390 | 1990-08-10 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CS9100483A2 true CS9100483A2 (en) | 1991-10-15 |
| CZ289263B6 CZ289263B6 (cs) | 2001-12-12 |
Family
ID=26382533
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US5310735A (cs) |
| EP (1) | EP0443883A1 (cs) |
| KR (1) | KR910021402A (cs) |
| AU (1) | AU646012B2 (cs) |
| CA (1) | CA2036941A1 (cs) |
| CZ (1) | CZ289263B6 (cs) |
| FI (1) | FI96863C (cs) |
| HU (1) | HUT58100A (cs) |
| IE (1) | IE910606A1 (cs) |
| NO (1) | NO178498C (cs) |
| NZ (1) | NZ237191A (cs) |
| PT (1) | PT96872A (cs) |
| RU (1) | RU2059639C1 (cs) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU631671B2 (en) * | 1989-08-04 | 1992-12-03 | Banyu Pharmaceutical Co., Ltd. | 2-(2-vinylpyrrolidinylthio)carbapenem derivatives |
| NZ237191A (en) * | 1990-02-23 | 1992-12-23 | Sankyo Co | 2-((substituted amide) substituted heterocyclylthio) carbpen-2-em derivatives and pharmaceutical compositions |
| GB9107363D0 (en) * | 1991-04-08 | 1991-05-22 | Ici Plc | Antibiotic compounds |
| US5554606A (en) * | 1990-03-12 | 1996-09-10 | Zeneca Limited | Antibiotic compounds |
| GB9107341D0 (en) * | 1991-04-08 | 1991-05-22 | Ici Plc | Antibiotic compounds |
| US5712267A (en) * | 1991-06-04 | 1998-01-27 | Sankyo Company,. Limited | Carbapenem derivatives, their preparation and their use as antibiotics |
| AU651887B2 (en) * | 1991-06-04 | 1994-08-04 | Sankyo Company Limited | 1-methylcarbapenem derivatives, their preparation and their use as antibiotics |
| GB9202298D0 (en) * | 1992-02-04 | 1992-03-18 | Ici Plc | Antibiotic compounds |
| HU218676B (hu) * | 1992-03-11 | 2000-10-28 | Sankyo Co. Ltd. | Antimikrobiális karbapenemszármazékok, ilyen vegyületeket tartalmazó gyógyászati készítmények és eljárás ezek előállítására |
| GB9304156D0 (en) * | 1992-03-26 | 1993-04-21 | Zeneca Ltd | Antibiotic compounds |
| EP0581501B1 (en) * | 1992-07-21 | 1998-09-09 | Zeneca Limited | Antibiotic carbapenem compounds |
| CA2099817A1 (en) * | 1992-07-21 | 1994-01-22 | Frederic H. Jung | Antibiotic compounds |
| EP0581502B1 (en) * | 1992-07-21 | 1998-10-21 | Zeneca Limited | Antibiotic carbapenem compounds |
| CA2099818A1 (en) * | 1992-07-21 | 1994-01-22 | Frederic H. Jung | Antibiotic compounds |
| CA2099811A1 (en) * | 1992-07-21 | 1994-01-22 | Frederic H. Jung | Antibiotic compounds |
| CA2106141A1 (en) * | 1992-09-28 | 1994-03-29 | Michael J. Betts | Antibiotic compounds |
| EP0590885B1 (en) * | 1992-09-28 | 2000-03-15 | Zeneca Limited | Antibiotic carbapenem compounds |
| CA2106330A1 (en) * | 1992-10-07 | 1994-04-08 | Patrice J. Siret | Antibiotic compounds |
| AU4912393A (en) * | 1993-06-15 | 1994-12-22 | Dong Kook Pharmaceutical Co., Ltd. | 1-beta-methyl-2-thiolic carbapenem derivatives |
| GB9515975D0 (en) | 1995-08-04 | 1995-10-04 | Zeneca Ltd | Chemical compounds |
| NZ332453A (en) * | 1996-04-26 | 2000-09-29 | Sankyo Co | (1R,5S,6S)-6-[(1R)-1-hydroxyethyl]-1-methyl-2-[(2S,4S)-2-[(3R)-3-methylaminomethylpyrrolidin-1-ylcarbonyl]pyrrolidin-4-ylthio]-1-carbapen-2-em-3-carboxylic acid for the prevention or treatment of bacterial infections |
| JP2001500118A (ja) | 1996-08-17 | 2001-01-09 | ゼネカ・リミテッド | ファルネシルタンパク質トランスフェラーゼ阻害剤としての３―メルカプトピロリジン |
| CA2303446C (en) | 1997-09-13 | 2004-10-26 | Korea Institute Of Science And Technology | Carbapenem derivatives and a preparation method thereof |
| YU66700A (sh) * | 1998-05-01 | 2003-01-31 | Kyoto Pharmaceutical Industries Ltd. | Derivati karbapenema, njihovo korišćenje i intermedijarna jedinjenja istih |
| GB9930317D0 (en) | 1999-12-22 | 2000-02-09 | Zeneca Ltd | Novel compounds |
| GB9930318D0 (en) | 1999-12-22 | 2000-02-09 | Zeneca Ltd | Novel compounds |
| US7932381B2 (en) * | 2005-02-15 | 2011-04-26 | Shionogi & Co., Ltd. | Process for producing carbapenem derivative and intermediate crystal therefor |
| EP2177522B1 (en) | 2007-06-28 | 2013-09-04 | XuanZhu Pharma Co., Ltd. | Novel carbapenem derivatives |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3950357A (en) * | 1974-11-25 | 1976-04-13 | Merck & Co., Inc. | Antibiotics |
| US4194047A (en) * | 1975-11-21 | 1980-03-18 | Merck & Co., Inc. | Substituted N-methylene derivatives of thienamycin |
| NL8000469A (nl) * | 1980-01-25 | 1981-01-30 | Akzo Nv | Zonnecollector met een warmtewisselaar. |
| US4552873A (en) * | 1981-08-19 | 1985-11-12 | Sankyo Company Limited | Carbapenem compounds, and compositions containing them |
| AR241016A1 (es) * | 1983-03-08 | 1991-04-30 | Bristol Myeres Squibb Company | "derivados de aminotiol cuaternario, procedimiento para prepararlos y procedimiento para preparar compuestos de carbapenem a partir de dichos derivados". |
| CA1283906C (en) * | 1983-05-09 | 1991-05-07 | Makoto Sunagawa | .beta.-LACTAM COMPOUNDS AND PRODUCTION THEREOF |
| DK189686A (da) * | 1985-04-27 | 1986-10-28 | Sankyo Co | Carbapenemforbindelser og fremgangsmaade til fremstilling deraf samt middel indeholdende forbindelserne |
| EP0243686B1 (en) * | 1986-03-27 | 1992-07-15 | Sumitomo Pharmaceuticals Company, Limited | Beta-lactam compounds, and their production |
| NZ219892A (en) * | 1986-04-15 | 1991-02-26 | Merck & Co Inc | N-amino quaternised heteroarylium carbapenem derivatives and pharmaceutical compositions thereof |
| US4925838A (en) * | 1988-03-18 | 1990-05-15 | Fujisawa Pharmaceutical Company, Ltd. | 3-pyrrolidinylthio-1-azabicyclo[3.2.0]-hept-2-ene-2-carboxylic acid compounds |
| US5227376A (en) * | 1990-02-14 | 1993-07-13 | Sumitomo Pharmaceuticals Co., Ltd. | β-lactam compounds and their production |
| CA2036163C (en) * | 1990-02-14 | 2001-06-19 | Makoto Sunagawa | Novel beta-lactam compounds and their production |
| NZ237191A (en) * | 1990-02-23 | 1992-12-23 | Sankyo Co | 2-((substituted amide) substituted heterocyclylthio) carbpen-2-em derivatives and pharmaceutical compositions |
| AU644008B2 (en) * | 1990-08-10 | 1993-12-02 | Sumitomo Pharmaceuticals Company, Limited | Beta-lactam compounds, and their production and use |
-
1991
- 1991-02-22 NZ NZ237191A patent/NZ237191A/xx unknown
- 1991-02-22 IE IE060691A patent/IE910606A1/en unknown
- 1991-02-22 CA CA002036941A patent/CA2036941A1/en not_active Abandoned
- 1991-02-22 NO NO910723A patent/NO178498C/no unknown
- 1991-02-22 AU AU71322/91A patent/AU646012B2/en not_active Ceased
- 1991-02-22 FI FI910860A patent/FI96863C/fi not_active IP Right Cessation
- 1991-02-23 KR KR1019910002980A patent/KR910021402A/ko not_active Ceased
- 1991-02-25 EP EP91301497A patent/EP0443883A1/en not_active Withdrawn
- 1991-02-25 PT PT96872A patent/PT96872A/pt not_active Application Discontinuation
- 1991-02-25 HU HU91620A patent/HUT58100A/hu unknown
- 1991-02-25 CZ CS1991483A patent/CZ289263B6/cs not_active IP Right Cessation
-
1992
- 1992-08-31 US US07/938,483 patent/US5310735A/en not_active Expired - Fee Related
-
1993
- 1993-03-15 RU RU9393004744A patent/RU2059639C1/ru active
- 1993-10-27 US US08/143,996 patent/US5420119A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CZ289263B6 (cs) | 2001-12-12 |
| NZ237191A (en) | 1992-12-23 |
| AU646012B2 (en) | 1994-02-03 |
| PT96872A (pt) | 1991-10-31 |
| IE910606A1 (en) | 1991-08-28 |
| NO178498B (no) | 1996-01-02 |
| NO910723D0 (no) | 1991-02-22 |
| KR910021402A (ko) | 1991-12-20 |
| FI910860A7 (fi) | 1991-08-24 |
| EP0443883A1 (en) | 1991-08-28 |
| NO910723L (no) | 1991-08-26 |
| NO178498C (no) | 1996-04-10 |
| CA2036941A1 (en) | 1991-08-24 |
| FI910860A0 (fi) | 1991-02-22 |
| FI96863B (fi) | 1996-05-31 |
| US5420119A (en) | 1995-05-30 |
| HUT58100A (en) | 1992-01-28 |
| RU2059639C1 (ru) | 1996-05-10 |
| FI96863C (fi) | 1996-09-10 |
| HU910620D0 (en) | 1991-09-30 |
| AU7132291A (en) | 1991-08-29 |
| US5310735A (en) | 1994-05-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PD00 | Pending as of 2000-06-30 in czech republic | ||
| MM4A | Patent lapsed due to non-payment of fee |
Effective date: 19910225 |