CS961283A2 - Zpusob pripravy 1 substituovanych spiro(imidazolidin 4,3 indo lin) 2,2,5 trionu a spiro(pyrrolidin 3 - Google Patents

Zpusob pripravy 1 substituovanych spiro(imidazolidin 4,3 indo lin) 2,2,5 trionu a spiro(pyrrolidin 3

Info

Publication number: CS961283A2
Authority: CS; Czechoslovakia
Prior art keywords: spiro; trionu; substituovanych; imidazolidin; pyrrolidin
Prior art date: 1982-12-20

Application number

CS839612A

Other languages

English (en)

Other versions

CS240986B2 (en

Inventor

Geoffrey R Bedford

David R Brittain

Ronald Platt

Original Assignee

Ici Plc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1982-12-20

Filing date

1983-12-19

Publication date

1985-06-13

1983-12-19 Application filed by Ici Plc filed Critical Ici Plc

1985-06-13 Publication of CS961283A2 publication Critical patent/CS961283A2/cs

1986-03-13 Publication of CS240986B2 publication Critical patent/CS240986B2/cs

Links

125000003003 spiro group Chemical group 0.000 title abstract 4
WRYCSMQKUKOKBP-UHFFFAOYSA-N Imidazolidine Chemical compound C1CNCN1 WRYCSMQKUKOKBP-UHFFFAOYSA-N 0.000 title 1
RWRDLPDLKQPQOW-UHFFFAOYSA-N Pyrrolidine Chemical compound C1CCNC1 RWRDLPDLKQPQOW-UHFFFAOYSA-N 0.000 title 1
239000003085 diluting agent Substances 0.000 abstract 1
238000010438 heat treatment Methods 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
239000002904 solvent Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/10—Spiro-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/32—Oxygen atoms
- C07D209/38—Oxygen atoms in positions 2 and 3, e.g. isatin

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Diabetes (AREA)
Pharmacology & Pharmacy (AREA)
General Health & Medical Sciences (AREA)
Hematology (AREA)
Obesity (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Endocrinology (AREA)
Emergency Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Bioinformatics & Cheminformatics (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Physical Or Chemical Processes And Apparatus (AREA)
Devices For Conveying Motion By Means Of Endless Flexible Members (AREA)
Storage Of Web-Like Or Filamentary Materials (AREA)
Mechanical Pencils And Projecting And Retracting Systems Therefor, And Multi-System Writing Instruments (AREA)
Indole Compounds (AREA)

CS839612A 1982-12-20 1983-12-19 Preparation method of 1-substitute spiro(imidazoline-4,3indolin)-2,2,5-triones and spirio(pyrrolidin-3,3-indolin)-2,3,5-triones CS240986B2 (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB8236969		1982-12-20

Publications (2)

Publication Number	Publication Date
CS961283A2 true CS961283A2 (en)	1985-06-13
CS240986B2 CS240986B2 (en)	1986-03-13

Family

ID=10535286

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CS839612A CS240986B2 (en)	1982-12-20	1983-12-19	Preparation method of 1-substitute spiro(imidazoline-4,3indolin)-2,2,5-triones and spirio(pyrrolidin-3,3-indolin)-2,3,5-triones

Country Status (21)

Country	Link
EP (1)	EP0115679B1 (cs)
JP (1)	JPS59118787A (cs)
KR (1)	KR840007407A (cs)
AT (1)	ATE30233T1 (cs)
AU (1)	AU567312B2 (cs)
CA (1)	CA1209148A (cs)
CS (1)	CS240986B2 (cs)
DD (1)	DD216935A5 (cs)
DE (1)	DE3374060D1 (cs)
DK (1)	DK579283A (cs)
ES (1)	ES8600298A1 (cs)
FI (1)	FI834637A7 (cs)
GB (1)	GB8331194D0 (cs)
GR (1)	GR79707B (cs)
HU (1)	HU189824B (cs)
IE (1)	IE56288B1 (cs)
NO (1)	NO834687L (cs)
NZ (1)	NZ206619A (cs)
PL (1)	PL245203A1 (cs)
PT (1)	PT77848B (cs)
ZA (1)	ZA838930B (cs)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB8415635D0 (en) *	1984-06-19	1984-07-25	Ici Plc	Cyclic amides
AR059265A1 (es)	2006-02-07	2008-03-19	Astrazeneca Ab	Compuestos espiro condensados con actividad inhibitoria en el receptor vaniloide1 (vr1)
WO2007091948A2 (en) *	2006-02-07	2007-08-16	Astrazeneca Ab	Novel spiro [imidazolidine-4, 3´-indole] 2, 2´,5´(1h) triones for treatment of conditions associated with vanilloid receptor 1

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3024231A (en) *	1959-02-11	1962-03-06	Spencer Chem Co	Racemization of d- and l-isomers of alpha-amino-epsilon-carprolactam
GB1569486A (en) *	1976-12-22	1980-06-18	Merck & Co Inc	Racemisationof 6-oxo-2-piperidine-carboxylic acid entantiomers
AU532110B2 (en) *	1979-11-13	1983-09-15	Ici Ltd.	Spiro(imidazolidine-4,3:-indoline)-2,2:5-trione derivatives
IE53102B1 (en) *	1981-05-12	1988-06-22	Ici Plc	Pharmaceutical spiro-succinimide derivatives
GB8312379D0 (en) *	1983-05-05	1983-06-08	Ici Plc	Heterocyclic compounds

1983
- 1983-11-23 GB GB838331194A patent/GB8331194D0/en active Pending
- 1983-11-29 IE IE2808/83A patent/IE56288B1/en not_active IP Right Cessation
- 1983-11-30 AU AU21852/83A patent/AU567312B2/en not_active Ceased
- 1983-11-30 ZA ZA838930A patent/ZA838930B/xx unknown
- 1983-12-07 EP EP83307446A patent/EP0115679B1/en not_active Expired
- 1983-12-07 AT AT83307446T patent/ATE30233T1/de not_active IP Right Cessation
- 1983-12-07 GR GR73172A patent/GR79707B/el unknown
- 1983-12-07 DE DE8383307446T patent/DE3374060D1/de not_active Expired
- 1983-12-15 DK DK579283A patent/DK579283A/da not_active Application Discontinuation
- 1983-12-16 DD DD83258088A patent/DD216935A5/de unknown
- 1983-12-16 FI FI834637A patent/FI834637A7/fi not_active Application Discontinuation
- 1983-12-19 KR KR1019830005998A patent/KR840007407A/ko not_active Withdrawn
- 1983-12-19 CS CS839612A patent/CS240986B2/cs unknown
- 1983-12-19 PL PL24520383A patent/PL245203A1/xx unknown
- 1983-12-19 ES ES528173A patent/ES8600298A1/es not_active Expired
- 1983-12-19 PT PT77848A patent/PT77848B/pt not_active IP Right Cessation
- 1983-12-19 HU HU834320A patent/HU189824B/hu unknown
- 1983-12-19 CA CA000443630A patent/CA1209148A/en not_active Expired
- 1983-12-19 NZ NZ206619A patent/NZ206619A/en unknown
- 1983-12-19 NO NO834687A patent/NO834687L/no unknown
- 1983-12-20 JP JP58239004A patent/JPS59118787A/ja active Pending

Also Published As

Publication number	Publication date
EP0115679A1 (en)	1984-08-15
PT77848B (en)	1986-07-11
FI834637A0 (fi)	1983-12-16
DK579283A (da)	1984-06-21
GR79707B (cs)	1984-10-31
AU2185283A (en)	1984-06-28
NO834687L (no)	1984-06-21
GB8331194D0 (en)	1983-12-29
CS240986B2 (en)	1986-03-13
IE56288B1 (en)	1991-06-05
FI834637A7 (fi)	1984-06-21
JPS59118787A (ja)	1984-07-09
NZ206619A (en)	1986-09-10
EP0115679B1 (en)	1987-10-14
ES528173A0 (es)	1985-10-01
ZA838930B (en)	1985-04-24
KR840007407A (ko)	1984-12-07
DD216935A5 (de)	1985-01-02
IE832808L (en)	1984-06-20
PT77848A (en)	1984-01-01
DE3374060D1 (en)	1987-11-19
DK579283D0 (da)	1983-12-15
AU567312B2 (en)	1987-11-19
HU189824B (en)	1986-08-28
ATE30233T1 (de)	1987-10-15
CA1209148A (en)	1986-08-05
ES8600298A1 (es)	1985-10-01
PL245203A1 (en)	1985-03-12

Publication	Publication Date	Title
DE3175042D1 (en)	1986-09-04	7-oxo-4-thia-1-aza(3,2,0)heptane and 7-oxo-4-thia-1-aza(3,2,0)hept-2-ene derivatives
AU4083589A (en)	1990-02-08	((1-lower alkyloxy-1-methyl)ethoxy)amines
PT80717A (en)	1985-07-01	Process for preparing benzodiazepine analogs
EP0310920A3 (en)	1990-08-22	Process for recovering trimethoxysilane from a trimethoxysilane and methanol mixture
HU911476D0 (en)	1991-11-28	Process for producing new pyrido(2,3-f) (1,4) thizepines and pyrido(3,2-b) (1,5)benzothiazepines
GR3031149T3 (en)	1999-12-31	Process for the manufacture of (s)-3-amino-1-substituted-pyrrolidines.
CS961283A2 (en)	1985-06-13	Zpusob pripravy 1 substituovanych spiro(imidazolidin 4,3 indo lin) 2,2,5 trionu a spiro(pyrrolidin 3
AU694653B2 (en)	1998-07-23	D4T polymorphic form I process
EP0476442A3 (en)	1992-10-14	L-gulono-gamma-lactone dehydrogenase
PT78598B (en)	1986-07-17	Process for preparing spiro-<indole<1,7-ab><1,5>benzodiazephin-2,4'-piperidines> and the intermediates therefor and pharmaceutical compositions containing them
AU621511B2 (en)	1992-03-12	3-aroyl-2-oxindole-1-carboxamides
GB8719695D0 (en)	1987-09-30	Chemical process
ZA913951B (en)	1992-03-25	Pyrido(3,4-b)pyrrolo(1,2-e)(1,4,5)oxadiazepines and related analogs,a process for their preparation and their use as medicaments
DE3464915D1 (en)	1987-08-27	(5-(2-aminomethyl-imidazol-1-yl)-1,3-dialkyl-1h-pyrazol-4-yl)(aryl)methanones and processes for their production
IE812607L (en)	1982-05-10	Heterobicyclic compounds
AU638158B2 (en)	1993-06-17	Carbamoyl-1-(pyridinylalkyl)-1h-indoles, indolines and related analogs
GB8707200D0 (en)	1987-04-29	Chemical process