CU20090200A7 - Una composición de liberación prolongada que comprende un derivado de somatostatina en micropartículas - Google Patents

Una composición de liberación prolongada que comprende un derivado de somatostatina en micropartículas

Info

Publication number
CU20090200A7
CU20090200A7 CU20090200A CU20090200A CU20090200A7 CU 20090200 A7 CU20090200 A7 CU 20090200A7 CU 20090200 A CU20090200 A CU 20090200A CU 20090200 A CU20090200 A CU 20090200A CU 20090200 A7 CU20090200 A7 CU 20090200A7
Authority
CU
Cuba
Prior art keywords
microparts
composition
prolonged release
somatostatin derivative
somatostatin
Prior art date
Application number
CU20090200A
Other languages
English (en)
Other versions
CU24028B1 (es
Inventor
Vitomir Vucenovic
Marc Riemenschnitter
Olivier Lambert
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38222465&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CU20090200(A7) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of CU20090200A7 publication Critical patent/CU20090200A7/es
Publication of CU24028B1 publication Critical patent/CU24028B1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/31—Somatostatins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
    • A61P5/04—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin for decreasing, blocking or antagonising the activity of the hypothalamic hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Obesity (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Rheumatology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Oncology (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Emergency Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurosurgery (AREA)
  • Ophthalmology & Optometry (AREA)
  • Biomedical Technology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Medicinal Preparation (AREA)

Abstract

La presente invención se refiere a micropartículas mejoradas que comprenden un análogo de somatostatina, a un proceso para la elaboración de estas micropartículas, y a composiciones farmacéuticas que la comprenden.
CU2009000200A 2007-05-24 2009-11-20 Proceso para obtener micropartículas mejoradas que comprenden un derivado de somatostatina CU24028B1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07108796 2007-05-24
PCT/EP2008/056347 WO2008142153A1 (en) 2007-05-24 2008-05-23 An extended-release composition comprising a somatostatin derivative in microparticles

Publications (2)

Publication Number Publication Date
CU20090200A7 true CU20090200A7 (es) 2011-09-21
CU24028B1 CU24028B1 (es) 2014-10-02

Family

ID=38222465

Family Applications (1)

Application Number Title Priority Date Filing Date
CU2009000200A CU24028B1 (es) 2007-05-24 2009-11-20 Proceso para obtener micropartículas mejoradas que comprenden un derivado de somatostatina

Country Status (42)

Country Link
US (2) US20100178344A1 (es)
EP (2) EP3666263A1 (es)
JP (1) JP5507447B2 (es)
KR (2) KR20100017904A (es)
CN (1) CN101677965B (es)
AR (1) AR066677A1 (es)
AU (1) AU2008252931B2 (es)
BR (1) BRPI0811904A2 (es)
CA (1) CA2683935C (es)
CL (1) CL2008001509A1 (es)
CO (1) CO6241097A2 (es)
CR (1) CR11078A (es)
CU (1) CU24028B1 (es)
DK (1) DK2164473T3 (es)
DO (1) DOP2009000262A (es)
EA (1) EA018203B1 (es)
EC (1) ECSP099793A (es)
ES (1) ES2761227T3 (es)
GE (1) GEP20125582B (es)
GT (1) GT200900302A (es)
HN (1) HN2009003296A (es)
HU (1) HUE046490T2 (es)
IL (1) IL201571B (es)
MA (1) MA31445B1 (es)
ME (1) ME00955B (es)
MX (1) MX2009012536A (es)
MY (1) MY148915A (es)
NI (1) NI200900207A (es)
NZ (1) NZ580589A (es)
PA (1) PA8781501A1 (es)
PE (1) PE20090387A1 (es)
PL (1) PL2164473T3 (es)
PT (1) PT2164473T (es)
SI (1) SI2164473T1 (es)
SM (1) SMP200900099B (es)
SV (1) SV2009003421A (es)
TN (1) TN2009000447A1 (es)
TW (1) TWI412373B (es)
UA (1) UA97396C2 (es)
UY (1) UY31103A1 (es)
WO (1) WO2008142153A1 (es)
ZA (1) ZA200907168B (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR057181A1 (es) * 2005-11-30 2007-11-21 Astra Ab Nueva forma de dosificacion de combinacion
RU2403914C2 (ru) * 2009-03-27 2010-11-20 Федеральное государственное учреждение Московский научно-исследовательский онкологический институт им. П.А. Герцена Федерального агентства по высокотехнологичной медицинской помощи (ФГУ МНИОИ им. П.А. Герцена Росмедтехнологий) Способ выбора тактики послеоперационного лечения медуллярного рака щитовидной железы
WO2012083026A1 (en) * 2010-12-15 2012-06-21 Evonik Degussa Corporation Branched polyol polyesters, blends and pharmaceutical formulations comprising same
EP3199146B1 (en) 2011-04-25 2019-07-17 Shan Dong Luye Pharmaceutical Co., Ltd. Risperidone sustained release microsphere composition
TWI562991B (en) 2012-04-23 2016-12-21 Otsuka Pharma Co Ltd Dihydrate of benzothiophene compound or of a salt thereof, and process for producing the same
AU2013265210B2 (en) * 2012-05-25 2016-09-15 Camurus Ab Somatostatin receptor agonist formulations
US10821200B2 (en) * 2016-12-05 2020-11-03 Hyalo Technologies, LLC Method of sterilization of microparticles
EP3339372A1 (en) * 2016-12-22 2018-06-27 Solvay SA Glycolic acid polymer composition
CN110870853B (zh) * 2018-08-29 2020-12-11 深圳翰宇药业股份有限公司 缓释帕瑞肽微球及其制备方法
MX2021006601A (es) * 2018-12-04 2021-07-07 Vanda Pharmaceuticals Inc Administracion de iloperidona de liberacion lenta.

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3773919A (en) 1969-10-23 1973-11-20 Du Pont Polylactide-drug mixtures
CH656884A5 (de) 1983-08-26 1986-07-31 Sandoz Ag Polyolester, deren herstellung und verwendung.
FI106926B (fi) * 1989-07-07 2001-05-15 Novartis Ag Menetelmä pitkäaikaisesti vapautuvan koostumuksen muodostamiseksi
PH30995A (en) 1989-07-07 1997-12-23 Novartis Inc Sustained release formulations of water soluble peptides.
US5538739A (en) 1989-07-07 1996-07-23 Sandoz Ltd. Sustained release formulations of water soluble peptides
CA2316052C (en) * 1989-07-07 2008-09-02 David Bodmer Sustained release formulations of water soluble peptides
IE960308A1 (en) * 1996-04-23 1997-11-05 Kinerton Ltd Sustained release ionic conjugate
AU5678398A (en) * 1997-01-29 1998-08-18 Takeda Chemical Industries Ltd. Sustained-release microspheres, their production and use
EP1240896A3 (en) 1998-07-23 2003-03-26 Societe De Conseils De Recherches Et D'applications Scientifiques S.A.S. Encapsulation of water soluble peptides
GB0018891D0 (en) 2000-08-01 2000-09-20 Novartis Ag Organic compounds
GB0326602D0 (en) * 2003-11-14 2003-12-17 Novartis Ag Organic compounds
MY158342A (en) * 2003-11-14 2016-09-30 Novartis Ag Pharmaceutical composition
EP1689429A1 (en) * 2003-11-25 2006-08-16 Novartis AG Biomarkers for the efficacy of somatostatin analogue treatment

Also Published As

Publication number Publication date
ES2761227T3 (es) 2020-05-19
HUE046490T2 (hu) 2020-03-30
UY31103A1 (es) 2009-01-05
SI2164473T1 (sl) 2020-02-28
EP3666263A1 (en) 2020-06-17
ZA200907168B (en) 2010-07-28
TW200906437A (en) 2009-02-16
CO6241097A2 (es) 2011-01-20
CL2008001509A1 (es) 2009-05-08
ECSP099793A (es) 2010-01-29
PA8781501A1 (es) 2008-12-18
MA31445B1 (fr) 2010-06-01
SMAP200900099A (it) 2010-01-19
BRPI0811904A2 (pt) 2014-11-18
JP2010527971A (ja) 2010-08-19
IL201571A0 (en) 2010-05-31
KR101930588B1 (ko) 2018-12-18
TWI412373B (zh) 2013-10-21
GEP20125582B (en) 2012-07-25
SMP200900099B (it) 2010-11-12
TN2009000447A1 (en) 2011-03-31
PL2164473T3 (pl) 2020-07-27
PT2164473T (pt) 2019-12-11
CA2683935A1 (en) 2008-11-27
KR20160002937A (ko) 2016-01-08
HN2009003296A (es) 2014-02-10
MY148915A (en) 2013-06-14
ME00955B (me) 2012-06-20
JP5507447B2 (ja) 2014-05-28
EP2164473B1 (en) 2019-09-11
GT200900302A (es) 2011-07-01
CA2683935C (en) 2016-07-19
NZ580589A (en) 2011-12-22
US9351923B2 (en) 2016-05-31
EP2164473A1 (en) 2010-03-24
US20130129798A1 (en) 2013-05-23
MX2009012536A (es) 2009-12-03
EA018203B1 (ru) 2013-06-28
KR20100017904A (ko) 2010-02-16
CU24028B1 (es) 2014-10-02
AU2008252931A1 (en) 2008-11-27
PE20090387A1 (es) 2009-04-28
DK2164473T3 (da) 2019-12-16
EA200901523A1 (ru) 2010-04-30
US20100178344A1 (en) 2010-07-15
WO2008142153A1 (en) 2008-11-27
IL201571B (en) 2018-11-29
AU2008252931B2 (en) 2011-09-01
AR066677A1 (es) 2009-09-02
SV2009003421A (es) 2010-05-21
DOP2009000262A (es) 2010-10-15
CN101677965A (zh) 2010-03-24
CN101677965B (zh) 2015-09-09
UA97396C2 (ru) 2012-02-10
CR11078A (es) 2009-12-04
NI200900207A (es) 2010-09-07

Similar Documents

Publication Publication Date Title
ECSP099793A (es) Una composición de liberación prolongada que comprende un derivado de somatostatina en micropartículas
BRPI0909030A2 (pt) composições farmacêuticas de liberação modificada compreendendo micofenolato e processos para as mesmas.
BRPI0918652A2 (pt) Composições farmacêuticas e métodos de libração relacionadas.
PH12013502192A1 (en) Antibodies against human angiopoietin 2
CR11740A (es) Composiciones que comprenden fármacos levemente básicos y formas de dosificación de liberación controlada
BRPI0919466A2 (pt) composição farmacêutica para liberação modificada
BRPI0909780A2 (pt) Composições e métodos para liberação de fármaco
BRPI0909820A2 (pt) Processo para estabilização de composição de vacina contra gripe, para estabilização de composição de vacina contendo adjuvante e para preparação de vacina, composições de vacina, kit de vacina e método de estocagem de uma matéria prima
IL202103A0 (en) Controlled release pharmaceutical compositions for prolonged effect
BRPI1011188A2 (pt) composições de liberação dérmica compreendendo complexos de partículas de agente ativo-fosfato de cálcio e métodos para usar as mesmas.
IL208203A (en) Annotations of 3,2-Dihydro-Pyrido-4,1-Exazine and 3,2-Dihydro-4-Oxa-9,1-Diazapananthrene, Preparation Processes and Pharmaceutical Preparations
BRPI0908596A2 (pt) formulação e composição farmacêutica de liberação prolongada
BR112015011430A2 (pt) composição para liberação imediata e prolongada
IL213452A0 (en) Phenylpyrimidone compounds, pharmaceutical compositions, preparation methods and uses thereof
MX2011013661A (es) Composiciones y metodos para el tratamiento de esclerosis multiple.
TN2009000510A1 (en) Extended release formulation of nevirapine
PT2362778T (pt) Composições que compreendem vitamina c
CL2008000695A1 (es) Compuestos derivados de macrolidos; procedimiento para la preparacion de dichos compuestos; composicion farmaceutica que comprende a dichos compuestos; y su uso en infecciones.
GT200800254A (es) 2-alcoxi-3,4,5-trihidroxi-alquilamida-benzotiazepinas, su preparacion, composiciones que las contienen y utilizacion.
UA96138C2 (ru) Жидкая концентрированная фармацевтическая композиция в форме спрея, которая содержит 3-гидрокси-6-метил-2-этилпиридина сукцинат (мексидол)
ZA201101045B (en) Modified release ramipril compositions and uses thereof
CL2007001026A1 (es) Metodo para tratar el hipogonadismo que comprende proporcionar una composicion farmaceutica de gel hidroalcoholico que comprende testosterona.
CL2008000550A1 (es) Compuestos derivados de pirazol-3-carboxamida en forma amorfa; disolucion solida amorfa; procedimiento de preparacion de la disolucion solida amorfa; y composicion farmaceutica que la comprende.

Legal Events

Date Code Title Description
FG Grant of patent