CU20120080A7 - Formulaciones de anticuerpo - Google Patents

Formulaciones de anticuerpo

Info

Publication number
CU20120080A7
CU20120080A7 CU2012000080A CU20120080A CU20120080A7 CU 20120080 A7 CU20120080 A7 CU 20120080A7 CU 2012000080 A CU2012000080 A CU 2012000080A CU 20120080 A CU20120080 A CU 20120080A CU 20120080 A7 CU20120080 A7 CU 20120080A7
Authority
CU
Cuba
Prior art keywords
antibody formulations
formulations
cryoprotectants
cryoprotectant
buffer
Prior art date
Application number
CU2012000080A
Other languages
English (en)
Inventor
Karthik Ramani
Sucharitha Jayakar
Original Assignee
Biocon Ltd
Ct De Inmunología Molecular
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biocon Ltd, Ct De Inmunología Molecular filed Critical Biocon Ltd
Publication of CU20120080A7 publication Critical patent/CU20120080A7/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39591—Stabilisation, fragmentation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Formulación estable farmacéuticamente que contiene anticuerpos, un búfer, un surfactante no iónico y lioprotectores/crioprotectores. Además se dan a conocer métodos asociados para la preparación, almacenamiento y uso de dichas formulaciones.
CU2012000080A 2009-11-20 2012-05-21 Formulaciones de anticuerpo CU20120080A7 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN2859CH2009 2009-11-20
PCT/IB2010/055296 WO2011061712A1 (en) 2009-11-20 2010-11-19 Formulations of antibody

Publications (1)

Publication Number Publication Date
CU20120080A7 true CU20120080A7 (es) 2012-10-15

Family

ID=44059267

Family Applications (1)

Application Number Title Priority Date Filing Date
CU2012000080A CU20120080A7 (es) 2009-11-20 2012-05-21 Formulaciones de anticuerpo

Country Status (20)

Country Link
US (4) US20120231009A1 (es)
EP (2) EP2501408B1 (es)
JP (2) JP5896471B2 (es)
KR (1) KR101333276B1 (es)
CN (1) CN102770157B (es)
AU (1) AU2010320515B2 (es)
BR (1) BR112012012080B1 (es)
CA (1) CA2781467C (es)
CU (1) CU20120080A7 (es)
DK (1) DK3721904T3 (es)
ES (1) ES2897500T3 (es)
IL (1) IL219884A (es)
MX (1) MX2012005863A (es)
MY (1) MY165614A (es)
NZ (1) NZ600096A (es)
PL (1) PL3721904T3 (es)
PT (1) PT3721904T (es)
RU (1) RU2548772C2 (es)
WO (1) WO2011061712A1 (es)
ZA (1) ZA201204459B (es)

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PT3024485T (pt) 2013-07-23 2021-01-25 Biocon Ltd Utilização de um parceiro de ligação de cd6 e método baseado no mesmo
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KR101776879B1 (ko) 2015-01-19 2017-09-08 주식회사 녹십자 항-egfr 항체를 포함하는 약학 제제
JP2018523684A (ja) 2015-08-18 2018-08-23 リジェネロン・ファーマシューティカルズ・インコーポレイテッドＲｅｇｅｎｅｒｏｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ． リポタンパク質アフェレーシスを受けている高脂血症の患者を治療するための抗ｐｃｓｋ９阻害抗体
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EP3529274B1 (en) 2016-10-21 2024-04-17 Biocon Limited A monoclonal antibody and a method of use for the treatment of lupus
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Also Published As

Publication number Publication date
US20210290525A1 (en) 2021-09-23
JP5896471B2 (ja) 2016-03-30
DK3721904T3 (da) 2021-11-15
BR112012012080A2 (es) 2021-11-03
JP2016104780A (ja) 2016-06-09
CN102770157B (zh) 2017-05-17
EP2501408A4 (en) 2014-10-08
US20240058263A1 (en) 2024-02-22
BR112012012080B1 (pt) 2022-11-29
ZA201204459B (en) 2013-02-27
KR101333276B1 (ko) 2013-11-27
PL3721904T3 (pl) 2022-01-31
EP3721904B1 (en) 2021-10-13
AU2010320515A1 (en) 2012-06-14
AU2010320515B2 (en) 2013-05-02
CA2781467A1 (en) 2011-05-26
EP3721904A1 (en) 2020-10-14
NZ600096A (en) 2013-08-30
CN102770157A (zh) 2012-11-07
EP2501408A1 (en) 2012-09-26
ES2897500T3 (es) 2022-03-01
MY165614A (en) 2018-04-18
CA2781467C (en) 2015-10-13
US20120231009A1 (en) 2012-09-13
MX2012005863A (es) 2013-01-18
IL219884A0 (en) 2012-07-31
IL219884A (en) 2015-11-30
KR20130028894A (ko) 2013-03-20
RU2548772C2 (ru) 2015-04-20
EP2501408B1 (en) 2020-05-27
ES2897500T8 (es) 2022-03-10
JP2013511510A (ja) 2013-04-04
PT3721904T (pt) 2021-11-15
WO2011061712A1 (en) 2011-05-26
RU2012125254A (ru) 2013-12-27
US20190321285A1 (en) 2019-10-24

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