CU20190005A7 - Goma de mascar administrable oralmente o formulaciones acuosas que comprenden un agente farmacéutico - Google Patents
Goma de mascar administrable oralmente o formulaciones acuosas que comprenden un agente farmacéuticoInfo
- Publication number
- CU20190005A7 CU20190005A7 CU2019000005A CU20190005A CU20190005A7 CU 20190005 A7 CU20190005 A7 CU 20190005A7 CU 2019000005 A CU2019000005 A CU 2019000005A CU 20190005 A CU20190005 A CU 20190005A CU 20190005 A7 CU20190005 A7 CU 20190005A7
- Authority
- CU
- Cuba
- Prior art keywords
- chewing gum
- orally administrable
- pharmaceutical agent
- aqueous formulations
- formulations including
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
- A61K9/0058—Chewing gums
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/05—Phenols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4468—Non condensed piperidines, e.g. piperocaine having a nitrogen directly attached in position 4, e.g. clebopride, fentanyl
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/658—Medicinal preparations containing organic active ingredients o-phenolic cannabinoids, e.g. cannabidiol, cannabigerolic acid, cannabichromene or tetrahydrocannabinol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/348—Cannabaceae
- A61K36/3482—Cannabis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Alternative & Traditional Medicine (AREA)
- Mycology (AREA)
- Pain & Pain Management (AREA)
- Zoology (AREA)
- Physiology (AREA)
- Nutrition Science (AREA)
- Emergency Medicine (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Dispersion Chemistry (AREA)
- Rheumatology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Confectionery (AREA)
- Medicines Containing Plant Substances (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
<p>Se proporciona una formulación de goma de mascar o formulación de base acuosa administrable por vía oral, que comprende una o más partículas que contienen agentes farmacéuticos que proporcionan una liberación rápida de los agentes farmacéuticos para su absorción en el sistema circulatorio de un mamífero. Las presentes formulaciones proporcionan un medio alternativo aceptable para administrar agentes farmacéuticos como los derivados de cannabinoides para el tratamiento del dolor y otras dolencias.</p> <p> </p> <p> </p>
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15/222,019 US9833408B1 (en) | 2016-07-28 | 2016-07-28 | Orally administrable formulation |
| PCT/CA2017/050904 WO2018018152A1 (en) | 2016-07-28 | 2017-07-28 | Novel orally administrable formulation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CU20190005A7 true CU20190005A7 (es) | 2020-03-04 |
Family
ID=60451833
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CU2019000005A CU20190005A7 (es) | 2016-07-28 | 2017-07-28 | Goma de mascar administrable oralmente o formulaciones acuosas que comprenden un agente farmacéutico |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US9833408B1 (es) |
| EP (2) | EP4353221A3 (es) |
| JP (2) | JP7050777B2 (es) |
| AU (2) | AU2017301239B2 (es) |
| BR (2) | BR122020007418B1 (es) |
| CL (1) | CL2019000209A1 (es) |
| CO (1) | CO2019001895A2 (es) |
| CU (1) | CU20190005A7 (es) |
| IL (1) | IL264484A (es) |
| MX (1) | MX383529B (es) |
| PE (1) | PE20190738A1 (es) |
| WO (1) | WO2018018152A1 (es) |
| ZA (2) | ZA201901116B (es) |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9833408B1 (en) * | 2016-07-28 | 2017-12-05 | Allen Greenspoon | Orally administrable formulation |
| US10239808B1 (en) | 2016-12-07 | 2019-03-26 | Canopy Holdings, LLC | Cannabis extracts |
| US11699166B2 (en) | 2017-10-09 | 2023-07-11 | American Express Travel Related Services Company, Inc. | Multi-merchant loyalty point partnership |
| US11397962B2 (en) | 2017-10-09 | 2022-07-26 | American Express Travel Related Services Company, Inc. | Loyalty point distributions using a decentralized loyalty ID |
| US11449887B2 (en) | 2017-10-09 | 2022-09-20 | American Express Travel Related Services Company, Inc. | Systems and methods for loyalty point distribution |
| EP3745884A1 (en) | 2018-01-31 | 2020-12-09 | Canopy Holdings, Llc | Hemp powder |
| US11951086B2 (en) * | 2018-04-03 | 2024-04-09 | Pure Green Pharmaceuticals, Inc. | Tablet or composition having n-acyl ethanolamine and cannabinoid |
| EP3549579A1 (en) * | 2018-04-03 | 2019-10-09 | Sanofi Winthrop Industrie | Oral gum formulation and fabrication process thereof |
| US11728995B2 (en) | 2018-04-09 | 2023-08-15 | American Express Travel Related Services Company, Inc. | Reward point transfers using blockchain |
| US10783545B2 (en) | 2018-04-19 | 2020-09-22 | American Express Travel Related Services Company, Inc. | Reward point redemption for cryptocurrency |
| US20210346385A1 (en) * | 2018-09-21 | 2021-11-11 | MSB Holdings, Inc | Taste-masked dosage forms |
| CA3119729A1 (en) | 2018-10-10 | 2020-04-16 | Treehouse Biotech, Inc. | Synthesis of cannabigerol |
| WO2020151789A1 (en) * | 2019-01-25 | 2020-07-30 | Medcan Pharma A/S | Cannabinoid chewing gum with polyvinyl acetate elastomer plasticizers |
| US11013685B2 (en) * | 2019-01-25 | 2021-05-25 | Nordiccan A/S | Cannabinoid chewing gum with improved release of cannabinoids |
| WO2020151793A1 (en) * | 2019-01-25 | 2020-07-30 | Medcan Pharma A/S | Chewing gum with improved delivery of cannabinoids |
| US11191720B2 (en) | 2019-01-25 | 2021-12-07 | Nordiccan A/S | Chewing gum with improved delivery of cannabinoids |
| US11406593B2 (en) | 2019-01-25 | 2022-08-09 | Nordiccan A/S | Cannabinoid chewing gum with high intensity sweeteners |
| MX2021008935A (es) * | 2019-01-25 | 2021-08-24 | Nordiccan As | Goma de mascar de cannabinoide con alcoholes de azucar. |
| EP3914226A1 (en) * | 2019-01-25 | 2021-12-01 | NordicCan A/S | Cannabinoid chewing gum with improved release of cannabinoids |
| US11166910B2 (en) | 2019-01-25 | 2021-11-09 | Nordiccan A/S | Cannabinoid chewing gum with sugar alcohols |
| CN113365503A (zh) * | 2019-01-25 | 2021-09-07 | 诺狄更斯公司 | 具有高强度甜味剂的大麻素口香糖 |
| US11154496B2 (en) * | 2019-01-25 | 2021-10-26 | Nordiccan A/S | Cannabinoid chewing gum with polyvinyl acetate elastomer plasticizers |
| US10933017B2 (en) | 2019-03-01 | 2021-03-02 | Nordiccan A/S | Tableted cannabinoid chewing gum with polyvinyl acetate elastomer plasticizers |
| US11253473B2 (en) * | 2019-03-01 | 2022-02-22 | Nordiccan A/S | Method of producing tableted cannabinoid chewing gum |
| US10799450B2 (en) | 2019-03-01 | 2020-10-13 | Medcan Pharma A/S | Tableted cannabinoid chewing gum with layered structure |
| US11471405B2 (en) | 2019-03-01 | 2022-10-18 | Nordiccan A/S | Tableted chewing gum with enhanced delivery of cannabinoids |
| US11331309B2 (en) * | 2019-06-05 | 2022-05-17 | Cure Pharmaceutical Holding Corp. | Methods and compositions for improving sleep |
| US20220273558A1 (en) * | 2019-08-02 | 2022-09-01 | Advanced Female Technologies Llc | Chewing Gum Compositions Containing Cannabinoids |
| US20220378677A1 (en) * | 2019-10-31 | 2022-12-01 | M. Mustix Ltd | Treatment of tooth decay using a chewing gum composition comprising cannabinoids |
| WO2021116825A1 (en) * | 2019-12-09 | 2021-06-17 | Nicoventures Trading Limited | Oral product |
| EP4072516A1 (en) | 2019-12-09 | 2022-10-19 | Nicoventures Trading Limited | Oral product comprising a cannabinoid |
| US11058142B1 (en) | 2020-10-01 | 2021-07-13 | Tobacco Technology, Inc. | Shisha, heat-not-burn, or combustion casing with active ingredient, product and casing with active ingredient, and method of making the same |
| US11363834B2 (en) | 2020-10-01 | 2022-06-21 | Tobacco Technology, Inc. | Shisha, heat-not-burn, or combustion casing, product, and method of making the same |
| EP4243602A4 (en) * | 2020-11-16 | 2024-11-13 | Orcosa Inc. | Improved use of cannabinoids in the treatment of alzheimer's disease |
| US11672761B2 (en) | 2020-11-16 | 2023-06-13 | Orcosa Inc. | Rapidly infusing platform and compositions for therapeutic treatment in humans |
| US11839602B2 (en) | 2020-11-25 | 2023-12-12 | Nicoventures Trading Limited | Oral cannabinoid product with lipid component |
| WO2023272335A1 (en) * | 2021-06-30 | 2023-01-05 | Emyria | Cannabidiol formulation comprising a matrix pellet forming excipient |
| WO2023064318A1 (en) * | 2021-10-11 | 2023-04-20 | Natural Extraction Systems, LLC | Biphasic compositions comprising one or both of carbonate and phosphate |
| WO2025043046A1 (en) * | 2023-08-22 | 2025-02-27 | GlycosBio, INC. | Latex-compatible oil-based compositions |
| DK202330231A1 (en) * | 2023-09-27 | 2025-04-10 | Fertin Pharma As | Cannabidiol for alleviating xerostomia |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4816265A (en) * | 1986-12-23 | 1989-03-28 | Warner-Lambert Company | Sweetener delivery systems containing polyvinyl acetate |
| DK505588D0 (da) * | 1988-02-26 | 1988-09-09 | Jesper Hamburger | Middel og anvendelse af samme |
| US6132762A (en) * | 1997-05-05 | 2000-10-17 | Cristobal; Walter | Transcutaneous application of marijuana |
| US7648696B2 (en) * | 1999-08-20 | 2010-01-19 | Unimed Pharmaceuticals, Llc | Composition for inhalation comprising delta-9-tetrahydrocannabinol in a semiaqueous solvent |
| ATE353629T1 (de) * | 2000-03-09 | 2007-03-15 | Gw Pharma Ltd | Cannabis enthaltende pharmazeutische zusammensetzungen |
| AU2002234545A1 (en) * | 2000-12-07 | 2002-06-18 | Byk Gulden Lomberg Chemische Fabrik G.M.B.H. | Pharmaceutical preparation in the form of a suspension comprising an acid-labileactive ingredient |
| CA2438097C (en) * | 2001-02-14 | 2006-04-25 | Gw Pharma Limited | Cannabinoids pharmaceutical formulations |
| DE10109763A1 (de) * | 2001-02-28 | 2002-09-05 | Gruenenthal Gmbh | Pharmazeutische Salze |
| US6503532B1 (en) * | 2001-04-13 | 2003-01-07 | Murty Pharmaceuticals, Inc. | Pharmaceutical composition containing tetrahydrocannabinol and a transdermal/transcutaneous delivery method thereof |
| GB2391865B (en) * | 2002-08-14 | 2005-06-01 | Gw Pharma Ltd | Improvements in the extraction of pharmaceutically active components from plant materials |
| US6946150B2 (en) * | 2002-08-14 | 2005-09-20 | Gw Pharma Limited | Pharmaceutical formulation |
| US8911751B2 (en) * | 2005-10-11 | 2014-12-16 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Compositions for nasal delivery |
| US20080112895A1 (en) * | 2006-08-04 | 2008-05-15 | Insys Therapeutics Inc. | Aqueous dronabinol formulations |
| EP2184983A1 (en) * | 2007-08-06 | 2010-05-19 | Insys Therapeutics Inc. | Oral cannabinoid liquid formulations and methods of treatment |
| WO2009120080A1 (en) * | 2008-03-26 | 2009-10-01 | Mareda Holding Bv | Chewing gum compositions comprising cannabinoids |
| JP2012500843A (ja) * | 2008-08-29 | 2012-01-12 | サン・ファーマ・アドバンスド・リサーチ・カンパニー・リミテッド | マイクロパーティクル |
| JP5614571B2 (ja) * | 2009-12-25 | 2014-10-29 | ダイヤ製薬株式会社 | 咀嚼用ガム医薬品および咀嚼用ガム医薬品の製造方法 |
| JP2014506894A (ja) * | 2011-02-28 | 2014-03-20 | テクノロジーズ・クロロス・インク | 口腔吸収用の咀嚼可能なビヒクル |
| WO2013009928A1 (en) * | 2011-07-11 | 2013-01-17 | Organic Medical Research | Cannabinoid formulations |
| US9345771B2 (en) * | 2012-10-04 | 2016-05-24 | Insys Development Company, Inc. | Oral cannabinoid formulations |
| US10071053B2 (en) * | 2014-01-31 | 2018-09-11 | Pocket Tea, Llc | Tea composition for oral administration |
| US20160199299A1 (en) | 2015-01-09 | 2016-07-14 | Mark B. Uren | Cannabis Infused Chewing Composition |
| CN105124747B (zh) * | 2015-07-21 | 2018-04-10 | 中国烟草总公司广东省公司 | 一种烟草提取物微粒和胶基型口香烟及其制备方法 |
| US11529329B2 (en) * | 2016-05-27 | 2022-12-20 | Nordiccan A/S | Powdered composition comprising a complex between a cannabinoid and a basic ion exchange resin |
| US9833408B1 (en) * | 2016-07-28 | 2017-12-05 | Allen Greenspoon | Orally administrable formulation |
| CA2937471C (en) * | 2016-07-28 | 2019-02-05 | Allen Greenspoon | Orally administrable formulation |
-
2016
- 2016-07-28 US US15/222,019 patent/US9833408B1/en active Active
-
2017
- 2017-07-28 BR BR122020007418-3A patent/BR122020007418B1/pt active IP Right Grant
- 2017-07-28 JP JP2019526350A patent/JP7050777B2/ja not_active Expired - Fee Related
- 2017-07-28 PE PE2019000281A patent/PE20190738A1/es unknown
- 2017-07-28 EP EP24160275.4A patent/EP4353221A3/en not_active Withdrawn
- 2017-07-28 MX MX2019001169A patent/MX383529B/es unknown
- 2017-07-28 BR BR112019001572-8A patent/BR112019001572B1/pt not_active IP Right Cessation
- 2017-07-28 AU AU2017301239A patent/AU2017301239B2/en not_active Ceased
- 2017-07-28 WO PCT/CA2017/050904 patent/WO2018018152A1/en not_active Ceased
- 2017-07-28 EP EP17833153.4A patent/EP3490539B1/en active Active
- 2017-07-28 CU CU2019000005A patent/CU20190005A7/es unknown
- 2017-11-08 US US15/806,928 patent/US10456357B2/en active Active
-
2019
- 2019-01-25 CL CL2019000209A patent/CL2019000209A1/es unknown
- 2019-01-27 IL IL264484A patent/IL264484A/en unknown
- 2019-02-21 ZA ZA2019/01116A patent/ZA201901116B/en unknown
- 2019-02-27 CO CONC2019/0001895A patent/CO2019001895A2/es unknown
-
2020
- 2020-02-19 ZA ZA2020/01037A patent/ZA202001037B/en unknown
- 2020-10-21 AU AU2020257071A patent/AU2020257071B2/en not_active Ceased
-
2022
- 2022-03-29 JP JP2022054535A patent/JP2022088537A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| ZA202001037B (en) | 2020-07-29 |
| AU2017301239A1 (en) | 2019-03-14 |
| JP2019525963A (ja) | 2019-09-12 |
| MX383529B (es) | 2025-03-14 |
| US20180064645A1 (en) | 2018-03-08 |
| BR112019001572B1 (pt) | 2021-11-03 |
| EP4353221A2 (en) | 2024-04-17 |
| US9833408B1 (en) | 2017-12-05 |
| AU2017301239B2 (en) | 2020-10-08 |
| PE20190738A1 (es) | 2019-05-23 |
| IL264484A (en) | 2019-02-28 |
| US10456357B2 (en) | 2019-10-29 |
| JP7050777B2 (ja) | 2022-04-08 |
| EP3490539A1 (en) | 2019-06-05 |
| EP3490539B1 (en) | 2024-03-13 |
| BR122020007418B1 (pt) | 2021-11-03 |
| AU2020257071A1 (en) | 2020-11-19 |
| CL2019000209A1 (es) | 2019-09-27 |
| EP4353221A3 (en) | 2024-07-10 |
| JP2022088537A (ja) | 2022-06-14 |
| WO2018018152A1 (en) | 2018-02-01 |
| CO2019001895A2 (es) | 2019-05-31 |
| ZA201901116B (en) | 2020-10-28 |
| MX2019001169A (es) | 2019-08-29 |
| BR112019001572A2 (pt) | 2019-05-07 |
| EP3490539A4 (en) | 2020-08-12 |
| AU2020257071B2 (en) | 2021-03-25 |
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