CU23412A3 - Diagnóstico y tratamiento de enfermedades utilizando anticuerpos anti-anti-receptor de células t vbeta o péptidos que son reconocidos por dichos anticuerpos, y proteína reguladora de la secreción endocrina 1 (prse1) - Google Patents
Diagnóstico y tratamiento de enfermedades utilizando anticuerpos anti-anti-receptor de células t vbeta o péptidos que son reconocidos por dichos anticuerpos, y proteína reguladora de la secreción endocrina 1 (prse1)Info
- Publication number
- CU23412A3 CU23412A3 CU20000009A CU20000009A CU23412A3 CU 23412 A3 CU23412 A3 CU 23412A3 CU 20000009 A CU20000009 A CU 20000009A CU 20000009 A CU20000009 A CU 20000009A CU 23412 A3 CU23412 A3 CU 23412A3
- Authority
- CU
- Cuba
- Prior art keywords
- antibodies
- diseases
- cells
- prse1
- vbeta
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/42—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against immunoglobulins
- C07K16/4208—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig
- C07K16/4241—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig against anti-human or anti-animal Ig
- C07K16/4258—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig against anti-human or anti-animal Ig against anti-receptor Ig
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6854—Immunoglobulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/04—Endocrine or metabolic disorders
- G01N2800/042—Disorders of carbohydrate metabolism, e.g. diabetes, glucose metabolism
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/24—Immunology or allergic disorders
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Diabetes (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Rehabilitation Therapy (AREA)
- Rheumatology (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Transplantation (AREA)
- Obesity (AREA)
- Cardiology (AREA)
Abstract
La presente invención proporciona anticuerpos monoclonales y policlonales que reconocen moléculas en células secretorias de varios tejidos blanco de enfermedades autoinmunitarias, permitiendo de esta manera un método unificado para prevenir y tratar enfermedades autoinmunitarias y otros trastornos en donde están involucradas la regulación alterada hormonal, la hiperinsulinemia y la resistencia a la insulina. También proporciona un método para detectar anticuerpos similares en suero humano u otros fluidos corporales, el cual se puede utilizar en el desarrollo de paquetes para diagnóstico. Los métodos de tratamiento que surgen de la presente invención, comprenden la administración de preparaciones de los anticuerpos, sus moleculas blanco y vectores que codifican para secuencias de los anticuerpos y sus moléculas blanco.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB9715281A GB2327423B (en) | 1997-07-21 | 1997-07-21 | Ligands, including antibodies, showing reactivity against endocrine cells for use in therapy and diagnosis |
| GBGB9810676.8A GB9810676D0 (en) | 1998-05-18 | 1998-05-18 | Ligands including antibodies showing reactivity against endocrine cells for use in therapy and diagnosis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CU23412A3 true CU23412A3 (es) | 2009-09-08 |
Family
ID=26311906
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CU20000009A CU23412A3 (es) | 1997-07-21 | 2000-01-18 | Diagnóstico y tratamiento de enfermedades utilizando anticuerpos anti-anti-receptor de células t vbeta o péptidos que son reconocidos por dichos anticuerpos, y proteína reguladora de la secreción endocrina 1 (prse1) |
Country Status (21)
| Country | Link |
|---|---|
| US (2) | US6689359B1 (es) |
| EP (2) | EP0998556B1 (es) |
| JP (1) | JP2002511765A (es) |
| KR (2) | KR100567277B1 (es) |
| CN (1) | CN1330754C (es) |
| AT (1) | ATE297983T1 (es) |
| AU (1) | AU758455B2 (es) |
| BR (1) | BR9810118A (es) |
| CA (1) | CA2296842C (es) |
| CU (1) | CU23412A3 (es) |
| DE (1) | DE69830588T2 (es) |
| DK (1) | DK0998556T3 (es) |
| EA (1) | EA003131B1 (es) |
| ES (1) | ES2245034T3 (es) |
| IL (3) | IL133277A0 (es) |
| NZ (1) | NZ501424A (es) |
| PL (1) | PL204503B1 (es) |
| PT (1) | PT998556E (es) |
| SI (1) | SI0998556T1 (es) |
| TR (1) | TR200000181T2 (es) |
| WO (1) | WO1999005175A2 (es) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2003510049A (ja) * | 1999-09-23 | 2003-03-18 | ライジェル・ファーマシューティカルズ・インコーポレイテッド | Ｔｒａｆ４関連細胞周期タンパク質、組成物および使用法 |
| DE10303974A1 (de) | 2003-01-31 | 2004-08-05 | Abbott Gmbh & Co. Kg | Amyloid-β(1-42)-Oligomere, Verfahren zu deren Herstellung und deren Verwendung |
| GB2429013C (en) * | 2005-08-11 | 2012-11-28 | Arpi Matossian-Rogers | Peptides for treatment and diagnosis of autoimmunedisease |
| AU2012241141B2 (en) * | 2005-08-11 | 2015-08-20 | Arpi Matossian-Rogers | TCR-V-beta related peptides for treatment and diagnosis of autoimmune disease |
| BRPI0619249A2 (pt) | 2005-11-30 | 2011-09-20 | Abbott Lab | anticorpos anti-globulÈmeros-aß, frações que se ligam a antìgeno destes, hibridomas correspondentes, ácidos nucléicos, vetores, células hospedeiras, métodos de produzir os ditos anticorpos, composições compreendendo os ditos anticorpos, usos dos ditos anticorpos e métodos de usar os ditos anticorpos |
| PT1976877E (pt) | 2005-11-30 | 2014-04-29 | Abbvie Inc | Anticorpos monoclonais contra proteína beta-amilóide e suas utilizações |
| US8455626B2 (en) | 2006-11-30 | 2013-06-04 | Abbott Laboratories | Aβ conformer selective anti-aβ globulomer monoclonal antibodies |
| EP2124952A2 (en) | 2007-02-27 | 2009-12-02 | Abbott GmbH & Co. KG | Method for the treatment of amyloidoses |
| US8048420B2 (en) | 2007-06-12 | 2011-11-01 | Ac Immune S.A. | Monoclonal antibody |
| US8613923B2 (en) | 2007-06-12 | 2013-12-24 | Ac Immune S.A. | Monoclonal antibody |
| EP2586795B1 (en) | 2007-10-05 | 2018-05-16 | Genentech, Inc. | Use of anti-amyloid beta antibody in ocular diseases |
| EP2558494B1 (en) | 2010-04-15 | 2018-05-23 | AbbVie Inc. | Amyloid-beta binding proteins |
| AU2011282536B2 (en) | 2010-07-30 | 2015-12-24 | Ac Immune S.A. | Safe and functional humanized anti beta-amyloid antibody |
| CN105348387B (zh) | 2010-08-14 | 2020-08-25 | Abbvie 公司 | β淀粉样蛋白结合蛋白 |
| KR101640694B1 (ko) * | 2011-09-29 | 2016-07-18 | 셀스냅, 엘엘씨 | 독소생산능 시험용 조성물 및 방법 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2072356A1 (en) * | 1989-12-29 | 1991-06-30 | James L. Urban | Diagnosis and treatment of diseases |
| US5216132A (en) * | 1990-01-12 | 1993-06-01 | Protein Design Labs, Inc. | Soluble t-cell antigen receptor chimeric antigens |
| JPH06507384A (ja) | 1991-01-22 | 1994-08-25 | ザ イミューン レスポンス コーポレイション | 特定のｔ細胞群による病理的応答により生じる疾患に対するワクチン投与および方法 |
| US5480895A (en) * | 1991-09-27 | 1996-01-02 | New York Society For The Relief Of The Ruptured And Crippled, Maintaining The Hospital For Special Surgery | Method of producing antibodies to a restricted population of T lymphocytes, antibodies produced therefrom and methods of use thereof |
| US5891623A (en) * | 1992-11-09 | 1999-04-06 | Consorzio Per Le Biotecnologie | Diagnosis and treatment of AIDS onset |
| US5595721A (en) * | 1993-09-16 | 1997-01-21 | Coulter Pharmaceutical, Inc. | Radioimmunotherapy of lymphoma using anti-CD20 |
| US5589328A (en) * | 1994-08-04 | 1996-12-31 | Mahant; Vijay K. | Chemiluminescence assays based on indoxyl substrates, thioindoxyl substrates and other substrates |
-
1998
- 1998-07-20 AU AU84517/98A patent/AU758455B2/en not_active Ceased
- 1998-07-20 ES ES98935160T patent/ES2245034T3/es not_active Expired - Lifetime
- 1998-07-20 US US09/463,158 patent/US6689359B1/en not_active Expired - Fee Related
- 1998-07-20 NZ NZ501424A patent/NZ501424A/en not_active IP Right Cessation
- 1998-07-20 DK DK98935160T patent/DK0998556T3/da active
- 1998-07-20 PL PL338449A patent/PL204503B1/pl not_active IP Right Cessation
- 1998-07-20 EP EP98935160A patent/EP0998556B1/en not_active Expired - Lifetime
- 1998-07-20 BR BR9810118-8A patent/BR9810118A/pt not_active Application Discontinuation
- 1998-07-20 CA CA2296842A patent/CA2296842C/en not_active Expired - Fee Related
- 1998-07-20 WO PCT/GB1998/002151 patent/WO1999005175A2/en not_active Ceased
- 1998-07-20 KR KR1020007000632A patent/KR100567277B1/ko not_active Expired - Fee Related
- 1998-07-20 AT AT98935160T patent/ATE297983T1/de active
- 1998-07-20 SI SI9830782T patent/SI0998556T1/xx unknown
- 1998-07-20 EP EP05076378A patent/EP1595951A1/en not_active Withdrawn
- 1998-07-20 CN CNB988073803A patent/CN1330754C/zh not_active Expired - Fee Related
- 1998-07-20 IL IL13327798A patent/IL133277A0/xx active IP Right Grant
- 1998-07-20 DE DE69830588T patent/DE69830588T2/de not_active Expired - Lifetime
- 1998-07-20 JP JP50949099A patent/JP2002511765A/ja not_active Ceased
- 1998-07-20 TR TR2000/00181T patent/TR200000181T2/xx unknown
- 1998-07-20 PT PT98935160T patent/PT998556E/pt unknown
- 1998-07-20 KR KR1020057007380A patent/KR100670070B1/ko not_active Expired - Fee Related
- 1998-07-20 EA EA200000146A patent/EA003131B1/ru not_active IP Right Cessation
-
1999
- 1999-12-02 IL IL133277A patent/IL133277A/en not_active IP Right Cessation
-
2000
- 2000-01-18 CU CU20000009A patent/CU23412A3/es not_active IP Right Cessation
-
2003
- 2003-10-01 US US10/674,433 patent/US20050100541A1/en not_active Abandoned
-
2006
- 2006-05-31 IL IL176076A patent/IL176076A/en not_active IP Right Cessation
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Legal Events
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| FD | Lapse (for not paying fees) |