CU23572A1 - Composición farmacéutica que comprende la proteína nmb0938 - Google Patents
Composición farmacéutica que comprende la proteína nmb0938Info
- Publication number
- CU23572A1 CU23572A1 CU20060074A CU20060074A CU23572A1 CU 23572 A1 CU23572 A1 CU 23572A1 CU 20060074 A CU20060074 A CU 20060074A CU 20060074 A CU20060074 A CU 20060074A CU 23572 A1 CU23572 A1 CU 23572A1
- Authority
- CU
- Cuba
- Prior art keywords
- composition
- nmb0938
- pharmaceutical composition
- composition including
- protein
- Prior art date
Links
- 108090000623 proteins and genes Proteins 0.000 title abstract 5
- 102000004169 proteins and genes Human genes 0.000 title abstract 4
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 abstract 3
- 102000053602 DNA Human genes 0.000 abstract 2
- 108020004414 DNA Proteins 0.000 abstract 2
- 239000003814 drug Substances 0.000 abstract 2
- 241000588650 Neisseria meningitidis Species 0.000 abstract 1
- 238000010171 animal model Methods 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000028993 immune response Effects 0.000 abstract 1
- 230000005847 immunogenicity Effects 0.000 abstract 1
- 239000012528 membrane Substances 0.000 abstract 1
- 244000052769 pathogen Species 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 230000001681 protective effect Effects 0.000 abstract 1
- 230000009257 reactivity Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/095—Neisseria
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/22—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6068—Other bacterial proteins, e.g. OMP
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmacology & Pharmacy (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Genetics & Genomics (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
La presente invención se relaciona con el campo de la medicina, particularmente con el desarrollo de una composición farmacéutica que comprende la proteína NMB0938. La composición de la presente invención confiere protección contra diferentes enfermedades, causadas o no por patógenos. La proteína NMB0938 se identificó como componente de las preparaciones de vesículas de membrana externa (VME) de Neisseria meningitidis, se obtuvo mediante la tecnología del ácido desoxirribonucleico (ADN) recombinante y se evaluó su inmunogenicidad y actividad protectora en modelos animales. Por el elevado grado de conservación del gen que codifica para la proteína NMB0938, la composición que la comprende posee alto valor como antígeno inductor de una respuesta inmune de amplia reactividad. La composición de esta invención es aplicable en la medicina humana.
Priority Applications (13)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CU20060074A CU23572A1 (es) | 2006-03-31 | 2006-03-31 | Composición farmacéutica que comprende la proteína nmb0938 |
| AU2007234213A AU2007234213A1 (en) | 2006-03-31 | 2007-03-29 | Pharmaceutical composition containing the NMB0938 protein |
| ARP070101322A AR060796A1 (es) | 2006-03-31 | 2007-03-29 | Composicion farmaceutica que comprende la proteina nmb0938 |
| PCT/CU2007/000011 WO2007112702A2 (es) | 2006-03-31 | 2007-03-29 | Composición farmacéutica que comprende la proteína nmb0938 |
| US12/295,436 US20090297547A1 (en) | 2006-03-31 | 2007-03-29 | Pharmaceutical composition containing the nmb0938 protein |
| MX2008012664A MX2008012664A (es) | 2006-03-31 | 2007-03-29 | Composicion farmaceutica que comprende la proteina nmb0938. |
| BRPI0710064-7A BRPI0710064A2 (pt) | 2006-03-31 | 2007-03-29 | composição farmacêutica contendo a proteìna nmb0938 |
| CNA2007800183602A CN101448522A (zh) | 2006-03-31 | 2007-03-29 | 包含蛋白质nmb0938的药物组合物 |
| KR1020087026337A KR20080106985A (ko) | 2006-03-31 | 2007-03-29 | Ｎｍｂ0938 단백질을 포함하는 약학적 조성물 |
| CA002649321A CA2649321A1 (en) | 2006-03-31 | 2007-03-29 | Pharmaceutical composition containing the nmb0938 protein |
| EP07721807A EP2011511A2 (en) | 2006-03-31 | 2007-03-29 | Pharmaceutical composition containing the nmb0938 protein |
| ZA200808760A ZA200808769B (en) | 2006-03-31 | 2008-10-14 | Pharmaceutical compostion containing the NMB0938 protein |
| NO20084524A NO20084524L (no) | 2006-03-31 | 2008-10-28 | Farmasoytisk sammensetning inneholdende NMB0938-protein |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CU20060074A CU23572A1 (es) | 2006-03-31 | 2006-03-31 | Composición farmacéutica que comprende la proteína nmb0938 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CU23572A1 true CU23572A1 (es) | 2010-09-30 |
Family
ID=38461832
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CU20060074A CU23572A1 (es) | 2006-03-31 | 2006-03-31 | Composición farmacéutica que comprende la proteína nmb0938 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20090297547A1 (es) |
| EP (1) | EP2011511A2 (es) |
| KR (1) | KR20080106985A (es) |
| CN (1) | CN101448522A (es) |
| AR (1) | AR060796A1 (es) |
| AU (1) | AU2007234213A1 (es) |
| BR (1) | BRPI0710064A2 (es) |
| CA (1) | CA2649321A1 (es) |
| CU (1) | CU23572A1 (es) |
| MX (1) | MX2008012664A (es) |
| NO (1) | NO20084524L (es) |
| WO (1) | WO2007112702A2 (es) |
| ZA (1) | ZA200808769B (es) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104079247B (zh) | 2013-03-26 | 2018-02-09 | 杜比实验室特许公司 | 均衡器控制器和控制方法以及音频再现设备 |
| CN107093991B (zh) | 2013-03-26 | 2020-10-09 | 杜比实验室特许公司 | 基于目标响度的响度归一化方法和设备 |
| RS65362B1 (sr) | 2016-09-02 | 2024-04-30 | Sanofi Pasteur Inc | Vakcina protiv neisseria meningitidis |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2261347A3 (en) * | 1998-05-01 | 2012-01-11 | Novartis Vaccines and Diagnostics, Inc. | Neisseria meningitidis antigens and compositions |
| AU783894B2 (en) * | 1999-05-19 | 2005-12-22 | Novartis Vaccines And Diagnostics S.R.L. | Combination neisserial compositions |
| CU23236A1 (es) * | 2003-12-03 | 2007-09-26 | Ct Ingenieria Genetica Biotech | PROTEINA NMB0928 Y SU USO EN FORMULACIONES FARMACéUTICAS P |
-
2006
- 2006-03-31 CU CU20060074A patent/CU23572A1/es unknown
-
2007
- 2007-03-29 KR KR1020087026337A patent/KR20080106985A/ko not_active Withdrawn
- 2007-03-29 CN CNA2007800183602A patent/CN101448522A/zh active Pending
- 2007-03-29 AR ARP070101322A patent/AR060796A1/es not_active Application Discontinuation
- 2007-03-29 MX MX2008012664A patent/MX2008012664A/es not_active Application Discontinuation
- 2007-03-29 WO PCT/CU2007/000011 patent/WO2007112702A2/es not_active Ceased
- 2007-03-29 EP EP07721807A patent/EP2011511A2/en not_active Withdrawn
- 2007-03-29 CA CA002649321A patent/CA2649321A1/en not_active Abandoned
- 2007-03-29 BR BRPI0710064-7A patent/BRPI0710064A2/pt not_active IP Right Cessation
- 2007-03-29 US US12/295,436 patent/US20090297547A1/en not_active Abandoned
- 2007-03-29 AU AU2007234213A patent/AU2007234213A1/en not_active Abandoned
-
2008
- 2008-10-14 ZA ZA200808760A patent/ZA200808769B/xx unknown
- 2008-10-28 NO NO20084524A patent/NO20084524L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EP2011511A2 (en) | 2009-01-07 |
| WO2007112702A2 (es) | 2007-10-11 |
| AR060796A1 (es) | 2008-07-16 |
| BRPI0710064A2 (pt) | 2011-08-02 |
| MX2008012664A (es) | 2008-10-13 |
| AU2007234213A1 (en) | 2007-10-11 |
| NO20084524L (no) | 2008-12-03 |
| ZA200808769B (en) | 2009-09-11 |
| CA2649321A1 (en) | 2007-10-11 |
| KR20080106985A (ko) | 2008-12-09 |
| WO2007112702A3 (es) | 2007-11-22 |
| US20090297547A1 (en) | 2009-12-03 |
| CN101448522A (zh) | 2009-06-03 |
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