CU24320B1 - Anticuerpos conjugados contra antígeno linfocitario 75 para el tratamiento del cáncer - Google Patents

Anticuerpos conjugados contra antígeno linfocitario 75 para el tratamiento del cáncer

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Publication number
CU24320B1
CU24320B1 CUP2016000042A CU20160042A CU24320B1 CU 24320 B1 CU24320 B1 CU 24320B1 CU P2016000042 A CUP2016000042 A CU P2016000042A CU 20160042 A CU20160042 A CU 20160042A CU 24320 B1 CU24320 B1 CU 24320B1
Authority
CU
Cuba
Prior art keywords
cancer
treatment
antibodies
lymphocytary
antigen
Prior art date
Application number
CUP2016000042A
Other languages
English (en)
Other versions
CU20160042A7 (es
Inventor
James Edward Ackroyd
Jonathan Alexander Terrett
Original Assignee
Berlin Chemie Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Berlin Chemie Ag filed Critical Berlin Chemie Ag
Publication of CU20160042A7 publication Critical patent/CU20160042A7/es
Publication of CU24320B1 publication Critical patent/CU24320B1/es

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    • A61K47/6851—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a determinant of a tumour cell
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Abstract

<p>La invención proporciona anticuerpos que se unen a LY75. También se proporcionan moléculas de ácido nucleico que codifican los anticuerpos, vectores de expresión, células hospedadoras y procedimientos para expresar los anticuerpos. Los anticuerpos se pueden usar para el tratamiento del cáncer, incluyendo cáncer de páncreas, cáncer de ovario, cáncer de mama, cáncer colorrectal, cáncer de esófago, cáncer de piel, cáncer de tiroides, cáncer de pulmón, cáncer de vejiga, mieloma múltiple y linfoma.</p>
CUP2016000042A 2013-10-11 2014-10-10 Anticuerpos conjugados contra antígeno linfocitario 75 para el tratamiento del cáncer CU24320B1 (es)

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PCT/GB2014/053057 WO2015052537A1 (en) 2013-10-11 2014-10-10 Conjugated antibodies against ly75 for the treatment of cancer

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