CY1114363T1 - Ανθελμινθικος συνδυασμος - Google Patents

Ανθελμινθικος συνδυασμος

Info

Publication number
CY1114363T1
CY1114363T1 CY20131100683T CY131100683T CY1114363T1 CY 1114363 T1 CY1114363 T1 CY 1114363T1 CY 20131100683 T CY20131100683 T CY 20131100683T CY 131100683 T CY131100683 T CY 131100683T CY 1114363 T1 CY1114363 T1 CY 1114363T1
Authority
CY
Cyprus
Prior art keywords
deoxoparaquamide
anthelmintic
anthelmintic combination
combination
avamectin
Prior art date
Application number
CY20131100683T
Other languages
English (en)
Inventor
Timothy G Geary
Peter Rolfe
Original Assignee
Zoetis Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zoetis Llc filed Critical Zoetis Llc
Publication of CY1114363T1 publication Critical patent/CY1114363T1/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/498—Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4995—Pyrazines or piperazines forming part of bridged ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/14—Ectoparasiticides, e.g. scabicides

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Παρέχεται μία μέθοδος για τη θεραπεία παρασιτικών μολύνσεων σε θηλαστικά, που περιλαμβάνει το στάδιο της ταυτόχρονης ή διαδοχικής χορήγησης στο θηλαστικό αποτελεσματικών ποσοτήτων (α) 2-δεσοξοπαραερκουαμιδίου, και (Β) αβαμηκτίνης. Επίσης παρέχεται μία ανθελμινθική σύνθεση που περιέχει 2-δεσοξοπαραερκουαμίδιο και αβαμηκτίνη.
CY20131100683T 2007-06-29 2013-08-09 Ανθελμινθικος συνδυασμος CY1114363T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US94701507P 2007-06-29 2007-06-29
EP08762949.9A EP2170321B1 (en) 2007-06-29 2008-06-16 Anthelmintic combination

Publications (1)

Publication Number Publication Date
CY1114363T1 true CY1114363T1 (el) 2016-08-31

Family

ID=39831661

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20131100683T CY1114363T1 (el) 2007-06-29 2013-08-09 Ανθελμινθικος συνδυασμος

Country Status (17)

Country Link
US (1) US8440633B2 (el)
EP (1) EP2170321B1 (el)
JP (1) JP5462456B2 (el)
CN (1) CN101686962B (el)
AR (1) AR067347A1 (el)
AU (1) AU2008272646B2 (el)
BR (1) BRPI0813235B1 (el)
CA (1) CA2690111C (el)
CY (1) CY1114363T1 (el)
DK (1) DK2170321T3 (el)
ES (1) ES2423505T3 (el)
NZ (1) NZ581859A (el)
PL (1) PL2170321T3 (el)
PT (1) PT2170321E (el)
TW (1) TWI352592B (el)
WO (1) WO2009004432A1 (el)
ZA (1) ZA201000672B (el)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL3050874T3 (pl) 2008-11-14 2019-07-31 Merial Inc. Wzbogacone enancjomerycznie aryloazol-2-ilocyjanoetyloaminowe związki pasożytobójcze
SG171751A1 (en) 2008-11-19 2011-07-28 Merial Ltd Compositions comprising an aryl pyrazole and/ or a formamidine methods and uses thereof
AR074482A1 (es) 2008-12-04 2011-01-19 Merial Ltd Derivados dimericos de avermectina y milbemicina
WO2011069143A1 (en) 2009-12-04 2011-06-09 Merial Limited Pesticidal bis-organosulfur compounds
ME02432B (me) 2009-12-17 2016-09-20 Merial Inc Antiparazitska jedinjenja dihidroazola i kompozicije koje ih sadrže
EP2512467A1 (en) 2009-12-17 2012-10-24 Merial Limited Compositions comprising macrocyclic lactone compounds and spirodioxepinoindoles
UA108641C2 (uk) 2010-04-02 2015-05-25 Паразитицидна композиція, яка містить чотири активних агенти, та спосіб її застосування
DK2640728T3 (en) 2010-11-16 2016-11-28 Merial Inc NEW MONENSINDERIVATER FOR TREATMENT AND PREVENTION OF protozoal INFECTIONS
WO2013003168A1 (en) 2011-06-27 2013-01-03 Merial Limited Novel insect-repellent coumarin derivatives, syntheses, and methods of use
US8946270B2 (en) 2011-06-27 2015-02-03 Merial Limited Amido-pyridyl ether compounds and compositions and their use against parasites
PT3172964T (pt) 2011-09-12 2020-11-30 Boehringer Ingelheim Animal Health Usa Inc Composições parasiticidas compreendendo um agente ativo de isoxazolina, método e utilizações das mesmas
WO2013044118A2 (en) 2011-09-23 2013-03-28 Merial Limited Indirect modeling of new repellent molecules active against insects, acarids, and other arthropods
JP6249568B2 (ja) 2011-11-17 2017-12-20 メリアル インコーポレイテッド アリールピラゾールと置換イミダゾールを含む組成物、その使用方法
BR122020002199B1 (pt) 2011-12-02 2021-01-19 Merial, Inc. formulações de moxidectina injetável de ação prolongada e novas formas de cristal de moxidectina
CN104168900A (zh) 2012-02-06 2014-11-26 梅里亚有限公司 包含全身性地起作用的活性剂的杀寄生虫口服兽用组合物、方法及其用途
JO3626B1 (ar) 2012-02-23 2020-08-27 Merial Inc تركيبات موضعية تحتوي على فيبرونيل و بيرميثرين و طرق استخدامها
NZ711847A (en) 2012-04-20 2015-11-27 Merial Inc Parasiticidal compositions comprising benzimidazole derivatives, methods and uses thereof
CA2891926A1 (en) 2012-11-20 2014-05-30 Merial, Inc. Anthelmintic compounds and compositions and method of using thereof
CN105873925B (zh) 2013-11-01 2019-09-10 勃林格殷格翰动物保健美国公司 抗寄生物的和杀虫的异噁唑啉化合物
ES2765405T3 (es) 2014-04-17 2020-06-09 Boehringer Ingelheim Animal Health Usa Inc Utilización de compuestos de malononitrilo para proteger animales de parásitos
MX375153B (es) 2014-05-19 2025-03-06 Boehringer Ingelheim Animal Health Usa Inc Compuestos antihelminticos.
BR122020023385B1 (pt) 2014-06-19 2021-05-25 Merial, Inc composições parasiticidas compreendendo derivados de indol, métodos e usos dos mesmos
US10864193B2 (en) 2014-10-31 2020-12-15 Boehringer Ingelheim Animal Health USA Inc. Parasiticidal compositions comprising fipronil at high concentrations
PY1609250A (es) 2015-02-26 2018-03-01 Merial Inc Formulaciones inyectables de acción prolongada que comprenden un agente activo isoxazolina, métodos y usos de las mismas
CN107835818B (zh) 2015-05-20 2022-04-29 勃林格殷格翰动物保健美国公司 驱虫缩酚酸肽化合物
UY37137A (es) 2016-02-24 2017-09-29 Merial Inc Compuestos antiparasitarios de isoxazolina, formulaciones inyectables de acción prolongada que los comprenden, métodos y usos de los mismos
WO2018039508A1 (en) 2016-08-25 2018-03-01 Merial, Inc. Method for reducing unwanted effects in parasiticidal treatments
CN110381738B (zh) 2016-10-14 2021-07-16 勃林格殷格翰动物保健美国公司 农药的和杀寄生物的乙烯基异噁唑啉化合物
EP3541789A1 (en) 2016-11-16 2019-09-25 Boehringer Ingelheim Animal Health USA Inc. Anthelmintic depsipeptide compounds
ES2944616T3 (es) 2017-08-14 2023-06-22 Boehringer Ingelheim Animal Health Usa Inc Compuestos de pirazol-isoxazolina plaguicidas y parasiticidas
EP3749096A1 (en) 2018-02-08 2020-12-16 Boehringer Ingelheim Animal Health USA Inc. Parasiticidal compositions comprising eprinomectin and praziquantel, methods and uses thereof
MX2021000293A (es) 2018-07-09 2021-07-15 Boehringer Ingelheim Animal Health Usa Inc Compuestos heterociclicos antihelminticos.
AR116524A1 (es) * 2018-10-04 2021-05-19 Elanco Tiergesundheit Ag Potenciación de tratamiento de helmintos
EP3883648A1 (en) 2018-11-20 2021-09-29 Boehringer Ingelheim Animal Health USA Inc. Indazolylcyanoethylamino compound, compositions of same, method of making, and methods of using thereof
PY2013845A (es) 2019-03-01 2021-02-09 Boehringer Ingelheim Animal Health Usa Inc Composiciones inyectables de clorsulón, sus métodos y usos
JP7637630B2 (ja) 2019-03-19 2025-02-28 ベーリンガー インゲルハイム フェトメディカ ゲーエムベーハー 駆虫性アザベンゾチオフェンおよびアザベンゾフラン化合物
PH12022553222A1 (en) 2020-05-29 2024-02-12 Boehringer Ingelheim Animal Health Usa Inc Anthelmintic heterocyclic compounds
JP2024504208A (ja) 2020-12-21 2024-01-30 ベーリンガー インゲルハイム フェトメディカ ゲーエムベーハー イソオキサゾリン化合物を含む殺寄生虫首輪
JP7857414B2 (ja) 2022-02-17 2026-05-12 ベーリンガー インゲルハイム フェトメディカ ゲーエムベーハー 流体製品メーラーを提供する方法及びシステム
WO2025257633A1 (en) 2024-06-12 2025-12-18 Boehringer Ingelheim Vetmedica Gmbh Long-acting castor oil-containing injectable formulations and methods of use thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ207655A (en) * 1983-04-07 1986-09-10 Merck & Co Inc Synergistic veterinary compositions containing an avermectin compound and clorsulon
GB2221621A (en) * 1988-08-12 1990-02-14 Merck & Co Inc Synergistic antiparasitic combinations of avermectin and pyrantel
PE20011289A1 (es) * 2000-04-07 2001-12-21 Upjohn Co Composiciones antihelminticas que comprenden lactonas macrociclicas y espirodioxepinoindoles
AU2003900505A0 (en) 2003-02-05 2003-02-20 Jurox Pty Ltd Anthelmintic composition

Also Published As

Publication number Publication date
JP5462456B2 (ja) 2014-04-02
JP2009051820A (ja) 2009-03-12
TWI352592B (en) 2011-11-21
NZ581859A (en) 2012-06-29
BRPI0813235A2 (pt) 2014-12-23
DK2170321T3 (da) 2013-07-29
BRPI0813235B1 (pt) 2019-01-22
TW200918044A (en) 2009-05-01
AR067347A1 (es) 2009-10-07
PL2170321T3 (pl) 2013-12-31
AU2008272646A1 (en) 2009-01-08
CN101686962B (zh) 2012-05-23
CA2690111A1 (en) 2009-01-08
PT2170321E (pt) 2013-08-01
US8440633B2 (en) 2013-05-14
ES2423505T3 (es) 2013-09-20
EP2170321A1 (en) 2010-04-07
WO2009004432A1 (en) 2009-01-08
US20100197624A1 (en) 2010-08-05
CA2690111C (en) 2011-11-15
AU2008272646B2 (en) 2013-08-22
EP2170321B1 (en) 2013-05-22
ZA201000672B (en) 2010-10-27
CN101686962A (zh) 2010-03-31

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