CY1119528T1 - Αναστολεις της δραστηριοτητας της κινασης - Google Patents

Αναστολεις της δραστηριοτητας της κινασης

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Publication number
CY1119528T1
CY1119528T1 CY20171101143T CY171101143T CY1119528T1 CY 1119528 T1 CY1119528 T1 CY 1119528T1 CY 20171101143 T CY20171101143 T CY 20171101143T CY 171101143 T CY171101143 T CY 171101143T CY 1119528 T1 CY1119528 T1 CY 1119528T1
Authority
CY
Cyprus
Prior art keywords
diseases
compounds
suspensions
inhibit
movement activity
Prior art date
Application number
CY20171101143T
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English (en)
Inventor
Christopher John Burns
Michael Francis Harte
James T. Palmer
Original Assignee
Ym Biosciences Australia Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AU2006906359A external-priority patent/AU2006906359A0/en
Application filed by Ym Biosciences Australia Pty Ltd filed Critical Ym Biosciences Australia Pty Ltd
Publication of CY1119528T1 publication Critical patent/CY1119528T1/el

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    • C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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Abstract

Η παρούσα εφεύρεση σχετίζεται με τις πυριδίνες ή πυραζίνες που αναστέλλουν τις κινάσες. Πιο συγκεκριμένα, οι χημικές ενώσεις της εφεύρεσης αναστέλλουν τα μέλη της τάξεως III της ΡΤΚ οικογένειας υποδοχών, όπως τα FMS (CSF-1R), c-KIT, PDG-FRβ, PDGFRα ή FLT3 και KDR, SRC, EphA2, EphA3, EphA8, FLT1, FLT4, HCK, LCK, PTK5 (FRK), SYK, DDR1 και DDR2 και RET. Οι χημικές ενώσεις της εφεύρεσης είναι χρήσιμες για την αγωγή των σχετικών με την κινάση νοσών, όπως οι ανοσοποιητικές και φλεγμονώδεις νόσοι. Οι υπερπλαστικές νόσοι που περιλαμβάνουν τον καρκίνο και νόσοι που περιλαμβάνουν τη νέο-αγγειογένεση. Νεφρικές νόσοι, νόσοι ανάπλασης οστού, μεταβολικά νοσήματα και αγγειακά νοσήματα.
CY20171101143T 2006-11-15 2017-11-02 Αναστολεις της δραστηριοτητας της κινασης CY1119528T1 (el)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AU2006906359A AU2006906359A0 (en) 2006-11-15 Inhibitors of kinase activity
US90151207P 2007-02-14 2007-02-14
EP07815564A EP2099774A4 (en) 2006-11-15 2007-11-15 INHIBITORS OF KINASEACTIVITY

Publications (1)

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CY1119528T1 true CY1119528T1 (el) 2018-03-07

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US (2) US8461161B2 (el)
EP (3) EP2099774A4 (el)
JP (5) JP5461189B2 (el)
AU (1) AU2007321719B2 (el)
CA (1) CA2701959C (el)
CY (1) CY1119528T1 (el)
DK (1) DK2848610T3 (el)
ES (1) ES2645947T3 (el)
HK (1) HK1225722A1 (el)
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