CY2015014I2 - Μακροκυκλικοι αναστολεις της πρωτεασης σερινης της ηπατιτιδας c - Google Patents

Μακροκυκλικοι αναστολεις της πρωτεασης σερινης της ηπατιτιδας c

Info

Publication number
CY2015014I2
CY2015014I2 CY2015014C CY2015014C CY2015014I2 CY 2015014 I2 CY2015014 I2 CY 2015014I2 CY 2015014 C CY2015014 C CY 2015014C CY 2015014 C CY2015014 C CY 2015014C CY 2015014 I2 CY2015014 I2 CY 2015014I2
Authority
CY
Cyprus
Prior art keywords
hepatitis
protease inhibitors
serine protease
macrocyclic serine
macrocyclic
Prior art date
Application number
CY2015014C
Other languages
English (en)
Other versions
CY2015014I1 (el
Original Assignee
Enanta Pharmaceuticals, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42005677&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY2015014(I2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Enanta Pharmaceuticals, Inc. filed Critical Enanta Pharmaceuticals, Inc.
Publication of CY2015014I2 publication Critical patent/CY2015014I2/el
Publication of CY2015014I1 publication Critical patent/CY2015014I1/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/113—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Analytical Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CY2015014C 2008-09-11 2015-03-26 Μακροκυκλικοι αναστολεις της πρωτεασης σερινης της ηπατιτιδας c CY2015014I1 (el)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US19172508P 2008-09-11 2008-09-11
US20968909P 2009-03-10 2009-03-10
PCT/US2009/005082 WO2010030359A2 (en) 2008-09-11 2009-09-10 Macrocyclic hepatitis c serine protease inhibitors

Publications (2)

Publication Number Publication Date
CY2015014I2 true CY2015014I2 (el) 2016-08-31
CY2015014I1 CY2015014I1 (el) 2016-08-31

Family

ID=42005677

Family Applications (6)

Application Number Title Priority Date Filing Date
CY20141100378T CY1115137T1 (el) 2008-09-11 2014-05-27 Μακροκυκλικοι αναστολεις της πρωτεασης σερινης της ηπατιτιδας c
CY20141100473T CY1115202T1 (el) 2008-09-11 2014-06-27 Μακροκυκλικοι αναστολεις της πρωτεασης σερινης της ηπατιτιδας c
CY20141100521T CY1115379T1 (el) 2008-09-11 2014-07-11 Μακροκυκλικοι αναστολεις της πρωτεασης σερινης της ηπατιτιδας c
CY20141101094T CY1115844T1 (el) 2008-09-11 2014-12-31 Μακροκυκλικοι αναστολεις της πρωτεασης σερινης της ηπατιτιδας c
CY2015014C CY2015014I1 (el) 2008-09-11 2015-03-26 Μακροκυκλικοι αναστολεις της πρωτεασης σερινης της ηπατιτιδας c
CY181100737T CY1120780T1 (el) 2008-09-11 2018-07-16 Μακροκυκλικοι αναστολεις πρωτεασης σερινης της ηπατιτιδας c

Family Applications Before (4)

Application Number Title Priority Date Filing Date
CY20141100378T CY1115137T1 (el) 2008-09-11 2014-05-27 Μακροκυκλικοι αναστολεις της πρωτεασης σερινης της ηπατιτιδας c
CY20141100473T CY1115202T1 (el) 2008-09-11 2014-06-27 Μακροκυκλικοι αναστολεις της πρωτεασης σερινης της ηπατιτιδας c
CY20141100521T CY1115379T1 (el) 2008-09-11 2014-07-11 Μακροκυκλικοι αναστολεις της πρωτεασης σερινης της ηπατιτιδας c
CY20141101094T CY1115844T1 (el) 2008-09-11 2014-12-31 Μακροκυκλικοι αναστολεις της πρωτεασης σερινης της ηπατιτιδας c

Family Applications After (1)

Application Number Title Priority Date Filing Date
CY181100737T CY1120780T1 (el) 2008-09-11 2018-07-16 Μακροκυκλικοι αναστολεις πρωτεασης σερινης της ηπατιτιδας c

Country Status (41)

Country Link
US (3) US8420596B2 (el)
EP (5) EP2468287B1 (el)
JP (4) JP5259537B2 (el)
KR (3) KR101379365B1 (el)
CN (3) CN101775017B (el)
AR (3) AR073568A1 (el)
AU (1) AU2009292182B2 (el)
BR (2) BRPI0918724B8 (el)
CA (1) CA2736895C (el)
CL (2) CL2011000512A1 (el)
CO (1) CO6341565A2 (el)
CR (1) CR20140180A (el)
CY (6) CY1115137T1 (el)
DK (5) DK2468287T3 (el)
DO (1) DOP2011000077A (el)
EA (2) EA022891B1 (el)
EC (2) ECSP11010879A (el)
ES (5) ES2459390T3 (el)
GT (2) GT201100056AA (el)
HR (5) HRP20140494T1 (el)
HU (2) HUE039478T2 (el)
IL (2) IL218441A (el)
LT (2) LT2805726T (el)
LU (1) LU92667I2 (el)
MX (1) MX2011002486A (el)
MY (1) MY159820A (el)
NL (1) NL300730I1 (el)
NO (1) NO2015014I1 (el)
NZ (2) NZ605550A (el)
PA (1) PA8842201A1 (el)
PE (3) PE20110704A1 (el)
PL (5) PL2468285T3 (el)
PT (5) PT2805726T (el)
SG (1) SG179414A1 (el)
SI (5) SI2468286T1 (el)
SM (1) SMT201800407T1 (el)
TR (1) TR201809771T4 (el)
TW (3) TWI429449B (el)
UY (3) UY32099A (el)
WO (1) WO2010030359A2 (el)
ZA (2) ZA201101558B (el)

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