CY2021027I2 - Σκευασματα αντισωματων anti-cd20 - Google Patents

Σκευασματα αντισωματων anti-cd20

Info

Publication number: CY2021027I2
Authority: CY; Cyprus
Prior art keywords: antibody preparation; antibody; preparation
Prior art date: 2007-07-06

Application number

CY2021027C

Other languages

English (en)

Other versions

CY2021027I1 (el

Original Assignee

Novartis Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-07-06

Filing date

2021-09-14

Publication date

2021-12-31

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40228991&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY2021027(I2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2021-09-14 Application filed by Novartis Ag filed Critical Novartis Ag

2021-12-31 Publication of CY2021027I2 publication Critical patent/CY2021027I2/el

2021-12-31 Publication of CY2021027I1 publication Critical patent/CY2021027I1/el

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2887—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD20
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39591—Stabilisation, fragmentation
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Immunology (AREA)
Dermatology (AREA)
Molecular Biology (AREA)
Virology (AREA)
Diabetes (AREA)
Epidemiology (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biochemistry (AREA)
Pulmonology (AREA)
Hematology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Oncology (AREA)
Biomedical Technology (AREA)
Mycology (AREA)
Microbiology (AREA)
Orthopedic Medicine & Surgery (AREA)
Urology & Nephrology (AREA)
Communicable Diseases (AREA)
Physical Education & Sports Medicine (AREA)
Rheumatology (AREA)
Pain & Pain Management (AREA)
Heart & Thoracic Surgery (AREA)

CY2021027C 2007-07-06 2021-09-14 Σκευασματα αντισωματων anti-cd20 CY2021027I1 (el)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US94822007P	2007-07-06	2007-07-06

Publications (2)

Publication Number	Publication Date
CY2021027I2 true CY2021027I2 (el)	2021-12-31
CY2021027I1 CY2021027I1 (el)	2021-12-31

Family

ID=40228991

Family Applications (3)

Application Number	Title	Priority Date	Filing Date
CY20171100043T CY1118419T1 (el)	2007-07-06	2017-01-12	Σκευασματα αντισωματων anti-cd20
CY20181100325T CY1120047T1 (el)	2007-07-06	2018-03-20	Σκευασματα αντισωματων
CY2021027C CY2021027I1 (el)	2007-07-06	2021-09-14	Σκευασματα αντισωματων anti-cd20

Family Applications Before (2)

Application Number	Title	Priority Date	Filing Date
CY20171100043T CY1118419T1 (el)	2007-07-06	2017-01-12	Σκευασματα αντισωματων anti-cd20
CY20181100325T CY1120047T1 (el)	2007-07-06	2018-03-20	Σκευασματα αντισωματων

Country Status (38)

Country	Link
US (2)	US20110020328A1 (el)
EP (2)	EP2889310B1 (el)
JP (1)	JP5529017B2 (el)
KR (2)	KR101670454B1 (el)
CN (1)	CN101820912B (el)
AR (2)	AR067455A1 (el)
AU (1)	AU2008275278B2 (el)
BR (2)	BRPI0814003B1 (el)
CA (1)	CA2692681C (el)
CL (1)	CL2008001984A1 (el)
CO (1)	CO6270340A2 (el)
CR (1)	CR11249A (el)
CY (3)	CY1118419T1 (el)
DK (2)	DK2889310T3 (el)
DO (1)	DOP2010000001A (el)
EA (1)	EA017994B1 (el)
ES (2)	ES2610821T3 (el)
FR (1)	FR21C1040I1 (el)
HR (2)	HRP20170033T1 (el)
HU (3)	HUE038501T2 (el)
IL (1)	IL202950A (el)
JO (1)	JO3219B1 (el)
LT (3)	LT2170388T (el)
MA (1)	MA31471B1 (el)
MX (1)	MX2010000017A (el)
MY (1)	MY210424A (el)
NO (2)	NO2889310T3 (el)
NZ (1)	NZ582250A (el)
PE (1)	PE20090738A1 (el)
PL (2)	PL2889310T3 (el)
PT (2)	PT2170388T (el)
SI (2)	SI2170388T1 (el)
TR (1)	TR201802928T4 (el)
TW (2)	TWI612060B (el)
UA (1)	UA107557C2 (el)
UY (1)	UY31210A1 (el)
WO (1)	WO2009009407A1 (el)
ZA (1)	ZA200909107B (el)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20160279239A1 (en)	2011-05-02	2016-09-29	Immunomedics, Inc.	Subcutaneous administration of anti-cd74 antibody for systemic lupus erythematosus and autoimmune disease
US20160355591A1 (en)	2011-05-02	2016-12-08	Immunomedics, Inc.	Subcutaneous anti-hla-dr monoclonal antibody for treatment of hematologic malignancies
UA107557C2 (xx) *	2007-07-06	2015-01-26		Композиція антитіла офатумумабу
EP2173163A4 (en) *	2007-07-06	2010-12-08	Glaxosmithkline Llc	ANTIBODY FORMULATIONS
EP3409289B1 (en)	2010-02-26	2020-09-30	Novo Nordisk A/S	Stable antibody containing compositions
RS59830B1 (sr)	2010-03-01	2020-02-28	Bayer Healthcare Llc	Optimizovana monoklonska antitela protiv inhibitora puta faktora tkiva (tfpi)
RU2012153786A (ru)	2010-05-28	2014-07-10	Ново Нордиск А/С	Стабильные многодозовые композиции, содержащие антитело и консервант
SG193964A1 (en) *	2011-04-07	2013-11-29	Glaxosmithkline Llc	Formulations with reduced viscosity
TWI907924B (zh) *	2011-05-02	2025-12-11	日商武田藥品工業股份有限公司	抗-α4β7抗體之調配物
AU2012250924B2 (en)	2011-05-02	2017-05-25	Immunomedics, Inc.	Ultrafiltration concentration of allotype selected antibodies for small-volume administration
UA116189C2 (uk)	2011-05-02	2018-02-26	Мілленніум Фармасьютікалз, Інк.	КОМПОЗИЦІЯ АНТИ-α4β7 АНТИТІЛА
UY34105A (es) *	2011-06-03	2012-07-31	Lg Life Sciences Ltd	Formulación líquida estable de etanercept
US9592297B2 (en)	2012-08-31	2017-03-14	Bayer Healthcare Llc	Antibody and protein formulations
UA117466C2 (uk)	2012-12-13	2018-08-10	Мерк Шарп Енд Доме Корп.	СТАБІЛЬНИЙ СКЛАД У ВИГЛЯДІ РОЗЧИНУ АНТИТІЛА ДО IL-23p19
CN105611909B (zh) *	2013-03-12	2020-09-15	普莱玛疗法公司	包含螯合剂和碱的牙用组合物
EP2805730A1 (en) *	2013-05-21	2014-11-26	Bergen Teknologioverforing AS	Nitric oxide donor for the treatment of chronic fatigue syndrome
WO2015162504A1 (en)	2014-04-23	2015-10-29	Novartis Ag	Novel dosing and uses of ofatumumab
WO2016189491A1 (en) *	2015-05-28	2016-12-01	Glaxosmithkline Intellectual Property Development Limited	Novel formulation
CN109563161A (zh) *	2016-02-03	2019-04-02	安口生物公司	用于提高抗体稳定性的缓冲制剂
RS64541B1 (sr)	2016-08-15	2023-09-29	Novartis Ag	Režimi i postupci za lečenje multiple skleroze upotrebom ofatumumaba
JPWO2018179138A1 (ja) *	2017-03-29	2020-02-06	持田製薬株式会社	抗体含有液体製剤
CN110352201A (zh)	2017-04-03	2019-10-18	免疫医疗公司	用于癌症疗法的抗体药物缀合物的皮下施用
RU2019138507A (ru)	2017-05-02	2021-06-02	Мерк Шарп И Доум Корп.	Составы антител против lag3 и совместные составы антител против lag3 и антител против pd-1
JOP20190260A1 (ar)	2017-05-02	2019-10-31	Merck Sharp & Dohme	صيغ ثابتة لأجسام مضادة لمستقبل الموت المبرمج 1 (pd-1) وطرق استخدامها
US11513046B2 (en) *	2018-02-09	2022-11-29	Championx Usa Inc.	Flowability testing systems and methods
CN113056482A (zh)	2018-10-18	2021-06-29	默沙东公司	抗rsv抗体的制剂及其使用方法
CN120842406A (zh)	2018-10-31	2025-10-28	默沙东有限责任公司	抗人pd-1抗体晶体及其使用方法
KR20210089215A (ko)	2018-11-07	2021-07-15	머크 샤프 앤드 돔 코포레이션	항-lag3 항체 및 항-pd-1 항체의 공동-제제
TWI874341B (zh)	2018-12-18	2025-03-01	美商健生生物科技公司	產生異二聚體抗體之方法
CN114401742B (zh)	2019-09-11	2024-05-24	诺华股份有限公司	通过转换疗法治疗rms
AU2020347474A1 (en)	2019-09-11	2022-04-07	Novartis Ag	Management of conditions other than multiple sclerosis in ofatumumab-treated patients
CN112675126A (zh) *	2019-10-18	2021-04-20	百奥泰生物制药股份有限公司	抗cd20抗体制剂及其应用
BR112022019038A2 (pt)	2020-04-09	2022-11-01	Novartis Ag	Ofatumumab para tratamento de em enquanto mantém a igg sérica
BR112022022730A2 (pt)	2020-05-08	2023-02-14	Genmab As	Método para tratar um linfoma não hodgkin de células b em um indivíduo humano
JP7057954B2 (ja) *	2020-09-03	2022-04-21	国立大学法人大阪大学	改善された保存安定性を有するタンパク質含有液体製剤
US20240228647A1 (en)	2021-04-14	2024-07-11	Novartis Ag	Ofatumumab for treating multiple sclerosis in asian patients
IL310813A (en)	2021-08-16	2024-04-01	Novartis Ag	OFATUMUMAB for the treatment of multiple sclerosis in children
JP2025513510A (ja) *	2022-04-20	2025-04-24	アルトスバイオロジックスインク．	オクレリズマブを含む薬学的組成物とその用途
CN116712390B (zh) *	2023-08-04	2023-11-14	上海览屹医药科技有限公司	一种高浓度高稳定性的抗体制剂及其制备方法
WO2025037335A1 (en) *	2023-08-12	2025-02-20	Dr. Reddy's Laboratories Limited	Formulations of anti-cd20 antibody

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4816567A (en)	1983-04-08	1989-03-28	Genentech, Inc.	Recombinant immunoglobin preparations
US4816401A (en) *	1985-09-09	1989-03-28	University Of Rochester	Serum free cell culture medium
DE3920358A1 (de)	1989-06-22	1991-01-17	Behringwerke Ag	Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung
DE69233528T2 (de)	1991-11-25	2006-03-16	Enzon, Inc.	Verfahren zur Herstellung von multivalenten antigenbindenden Proteinen
EP0999853B1 (en) *	1997-06-13	2003-01-02	Genentech, Inc.	Stabilized antibody formulation
CN1245216C (zh) *	1999-10-04	2006-03-15	希龙公司	稳定化的含多肽的液体药物组合物
US7754208B2 (en)	2001-01-17	2010-07-13	Trubion Pharmaceuticals, Inc.	Binding domain-immunoglobulin fusion proteins
RU2004127458A (ru)	2002-02-14	2005-10-27	Иммуномедикс, Инк. (Us)	Анти-cd20 антитела, их гибридные белки и способы их использования
SI1478394T1 (sl) *	2002-02-27	2008-12-31	Immunex Corp	STABILIZIRAN TNFR-Fc SESTAVEK Z ARGININOM
EP1551875A4 (en) *	2002-06-21	2006-06-28	Biogen Idec Inc	TAMPON PREPARATIONS FOR CONCENTRATING ANTIBODIES AND METHODS FOR USE THEREOF
KR20110017020A (ko) *	2002-10-17	2011-02-18	젠맵 에이/에스	Ｃｄ20에 대한 인간 모노클로날 항체
AU2003299641C1 (en) *	2002-12-16	2016-06-02	Cormorant Pharmaceuticals Ab	Human monoclonal antibodies against interleukin 8 (IL-8)
US8084582B2 (en) *	2003-03-03	2011-12-27	Xencor, Inc.	Optimized anti-CD20 monoclonal antibodies having Fc variants
AR044388A1 (es)	2003-05-20	2005-09-07	Applied Molecular Evolution	Moleculas de union a cd20
WO2005103081A2 (en)	2004-04-20	2005-11-03	Genmab A/S	Human monoclonal antibodies against cd20
DOP2006000029A (es) *	2005-02-07	2006-08-15	Genentech Inc	Antibody variants and uses thereof. (variantes de un anticuerpo y usos de las mismas)
LT2620450T (lt) *	2005-03-08	2019-02-11	Pfizer Products Inc.	Anti-ctla-4 antikūnų kompozicijos
PL1942939T5 (pl) *	2005-09-30	2021-10-11	Medimmune Limited	Kompozycja przeciwciała interleukiny-13
EP2173163A4 (en) *	2007-07-06	2010-12-08	Glaxosmithkline Llc	ANTIBODY FORMULATIONS
UA107557C2 (xx) *	2007-07-06	2015-01-26		Композиція антитіла офатумумабу

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Also Published As

Publication number	Publication date
HUE038501T2 (hu)	2018-10-29
BR122020026978B1 (pt)	2021-09-28
EP2170388A4 (en)	2011-07-06
WO2009009407A1 (en)	2009-01-15
CL2008001984A1 (es)	2009-01-09
EA201070105A1 (ru)	2010-08-30
ZA200909107B (en)	2012-12-27
PL2889310T3 (pl)	2018-06-29
MX2010000017A (es)	2010-04-07
TWI612060B (zh)	2018-01-21
BRPI0814003B1 (pt)	2021-06-15
PL2170388T3 (pl)	2017-06-30
HK1141979A1 (zh)	2010-11-26
MA31471B1 (fr)	2010-06-01
EP2889310A1 (en)	2015-07-01
JO3219B1 (ar)	2018-03-08
UY31210A1 (es)	2009-01-30
US20110020328A1 (en)	2011-01-27
HK1207652A1 (en)	2016-02-19
IL202950A0 (en)	2011-08-01
CA2692681C (en)	2018-12-04
DOP2010000001A (es)	2010-01-31
EP2170388A1 (en)	2010-04-07
CN101820912A (zh)	2010-09-01
TW201623334A (zh)	2016-07-01
KR20100038092A (ko)	2010-04-12
IL202950A (en)	2014-05-28
TWI515204B (zh)	2016-01-01
NZ582250A (en)	2012-04-27
EP2170388B1 (en)	2016-10-12
UA107557C2 (xx)	2015-01-26
BRPI0814003A2 (pt)	2015-02-03
ES2663504T3 (es)	2018-04-13
NO2889310T3 (el)	2018-05-19
SI2889310T1 (en)	2018-04-30
NO2021036I1 (no)	2021-09-13
JP5529017B2 (ja)	2014-06-25
CY1120047T1 (el)	2018-12-12
LT2889310T (lt)	2018-03-26
CO6270340A2 (es)	2011-04-20
SI2170388T1 (sl)	2017-01-31
KR20150088335A (ko)	2015-07-31
JP2011526880A (ja)	2011-10-20
EP2889310B1 (en)	2017-12-20
LT2170388T (lt)	2017-01-10
KR101670454B1 (ko)	2016-10-31
HRP20180440T1 (hr)	2018-04-20
US20150158951A1 (en)	2015-06-11
FR21C1040I1 (fr)	2021-11-19
CA2692681A1 (en)	2009-01-15
CY2021027I1 (el)	2021-12-31
AR067455A1 (es)	2009-10-14
ES2610821T3 (es)	2017-05-03
CY1118419T1 (el)	2017-06-28
AR109461A2 (es)	2018-12-12
CN101820912B (zh)	2014-03-12
PT2889310T (pt)	2018-03-26
PT2170388T (pt)	2017-01-04
MY210424A (en)	2025-09-22
CR11249A (es)	2010-03-08
EA017994B1 (ru)	2013-04-30
HRP20170033T1 (hr)	2017-03-24
DK2889310T3 (en)	2018-03-26
TW200914466A (en)	2009-04-01
DK2170388T3 (en)	2017-01-16
AU2008275278B2 (en)	2011-04-14
HUS2100038I1 (hu)	2021-10-28
LTPA2021520I1 (el)	2021-10-11
AU2008275278A1 (en)	2009-01-15
HUE031288T2 (hu)	2017-06-28
TR201802928T4 (tr)	2018-03-21
PE20090738A1 (es)	2009-07-18

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SI2126093T1 (sl)	2013-01-31	IzboljĹˇanje priprave proteinov
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DK3118220T3 (da)	2019-09-23	Protein
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NO20072812L (no)	2008-12-02	Forbedret oreenhet
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DK2125048T3 (da)	2014-10-13	Præparat
BRPI0909633A2 (pt)	2015-09-22	anticorpos anti-tyrp1
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BRPI0819765A2 (pt)	2015-05-05	Conjugados de anticorpos anti-rg-1