DD153689A5 - Verfahren zur herstellung eines sterisch gehinderten aminsalzes einer 6,7-dihalogen-3,4-dihydro-3-oxo-2-chinoxalincarbonsaeure - Google Patents

Verfahren zur herstellung eines sterisch gehinderten aminsalzes einer 6,7-dihalogen-3,4-dihydro-3-oxo-2-chinoxalincarbonsaeure Download PDF

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Publication number
DD153689A5
DD153689A5 DD80224744A DD22474480A DD153689A5 DD 153689 A5 DD153689 A5 DD 153689A5 DD 80224744 A DD80224744 A DD 80224744A DD 22474480 A DD22474480 A DD 22474480A DD 153689 A5 DD153689 A5 DD 153689A5
Authority
DD
German Democratic Republic
Prior art keywords
oxo
dihydro
acid
salt
adamantylamine
Prior art date
Application number
DD80224744A
Other languages
German (de)
English (en)
Inventor
Riaz F Abdulla
Donald C Delong
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of DD153689A5 publication Critical patent/DD153689A5/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
    • C07D241/38—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
    • C07D241/40—Benzopyrazines
    • C07D241/44—Benzopyrazines with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/07—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by halogen atoms
    • C07C205/11—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by halogen atoms having nitro groups bound to carbon atoms of six-membered aromatic rings
    • C07C205/12—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by halogen atoms having nitro groups bound to carbon atoms of six-membered aromatic rings the six-membered aromatic ring or a condensed ring system containing that ring being substituted by halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00—Compounds containing amino groups bound to a carbon skeleton
    • C07C211/33—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C211/39—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of an unsaturated carbon skeleton
    • C07C211/41—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of an unsaturated carbon skeleton containing condensed ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/96—Spiro-condensed ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/18—Systems containing only non-condensed rings with a ring being at least seven-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/36—Systems containing two condensed rings the rings having more than two atoms in common
    • C07C2602/42—Systems containing two condensed rings the rings having more than two atoms in common the bicyclo ring system containing seven carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/56—Ring systems containing bridged rings
    • C07C2603/58—Ring systems containing bridged rings containing three rings
    • C07C2603/70—Ring systems containing bridged rings containing three rings containing only six-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/56—Ring systems containing bridged rings
    • C07C2603/58—Ring systems containing bridged rings containing three rings
    • C07C2603/70—Ring systems containing bridged rings containing three rings containing only six-membered rings
    • C07C2603/74—Adamantanes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/56—Ring systems containing bridged rings
    • C07C2603/58—Ring systems containing bridged rings containing three rings
    • C07C2603/76—Ring systems containing bridged rings containing three rings containing at least one ring with more than six ring members

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
DD80224744A 1979-10-25 1980-10-24 Verfahren zur herstellung eines sterisch gehinderten aminsalzes einer 6,7-dihalogen-3,4-dihydro-3-oxo-2-chinoxalincarbonsaeure DD153689A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/088,275 US4252954A (en) 1979-10-25 1979-10-25 Salts of dihalo-3,4-dihydro-3-oxo-2-quinoxaline carboxylic acids and hindered amines

Publications (1)

Publication Number Publication Date
DD153689A5 true DD153689A5 (de) 1982-01-27

Family

ID=22210429

Family Applications (1)

Application Number Title Priority Date Filing Date
DD80224744A DD153689A5 (de) 1979-10-25 1980-10-24 Verfahren zur herstellung eines sterisch gehinderten aminsalzes einer 6,7-dihalogen-3,4-dihydro-3-oxo-2-chinoxalincarbonsaeure

Country Status (20)

Country Link
US (1) US4252954A (cs)
EP (1) EP0029658A1 (cs)
JP (1) JPS5681569A (cs)
AU (1) AU6351280A (cs)
BE (1) BE885793A (cs)
CA (1) CA1149381A (cs)
CS (1) CS212304B2 (cs)
DD (1) DD153689A5 (cs)
DK (1) DK449780A (cs)
ES (1) ES496210A0 (cs)
FI (1) FI803294L (cs)
FR (1) FR2467848A1 (cs)
GB (1) GB2061936A (cs)
GR (1) GR69994B (cs)
IL (1) IL61313A0 (cs)
IT (1) IT1134009B (cs)
PL (1) PL227421A1 (cs)
PT (1) PT71939B (cs)
YU (1) YU268880A (cs)
ZA (1) ZA806437B (cs)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD281614A5 (de) * 1988-09-02 1990-08-15 Univ Berlin Humboldt Verfahren zur herstellung von virostatisch wirksamendiazinsubstituierten 1-adamantanen
AU9049391A (en) * 1990-12-20 1992-07-22 Warner-Lambert Company 2-acylamido derivatives of 3,4-dihydro-3-oxo-quinoxaline having pharmaceutical activity
BR9811739A (pt) * 1997-09-01 2000-09-19 Kyorin Seiyaku Kk Derivados de ácido quinoxalinacarbóxilico assimetricamente dissubstituìdo em 6,7, seus sais de adição, e processos para a preparação de ambos
WO2004089296A2 (en) 2003-04-03 2004-10-21 The Regents Of The University Of California Improved inhibitors for the soluble epoxide hydrolase
EP1765311A4 (en) 2004-03-16 2009-04-29 Univ California REDUCTION OF NEPHROPATHY WITH INHIBITORS OF SOLUBLE EPOXY HYDROLASE AND EPOXYEICOSANOIDS
WO2006045119A2 (en) 2004-10-20 2006-04-27 The Regents Of The University Of California Improved inhibitors for the soluble epoxide hydrolase
AR059826A1 (es) * 2006-03-13 2008-04-30 Univ California Inhibidores de urea conformacionalmente restringidos de epoxido hidrolasa soluble
EP2528604B1 (en) 2010-01-29 2017-11-22 The Regents of the University of California Acyl piperidine inhibitors of soluble epoxide hydrolase
CN103168029A (zh) * 2010-10-08 2013-06-19 诺瓦提斯公司 磺酰胺ns3抑制剂的盐和多晶型物
JP6406159B2 (ja) 2015-08-04 2018-10-17 株式会社デンソー 車載表示制御装置、車載表示制御方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3355355A (en) * 1965-02-05 1967-11-28 Smith Kline French Lab Antiviral cycloalkylamine compositions and method
DE1770697C3 (de) * 1967-07-06 1981-04-23 Dupher International Research B.V., Weesp 2,2-(N-Methyl-2-azatetramethylen)- -adamantan, dessen Salze, Verfahren zu deren Herstellung und Arzneimittel
GB1438349A (en) * 1973-09-13 1976-06-03 Post Office Conductor assemblies for cables
US4181724A (en) * 1978-09-11 1980-01-01 The Upjohn Company Quinoxalinone compounds useful for expanding the lumina or air passages in mammals
GR72941B (cs) * 1978-10-20 1984-01-16 Lilly Co Eli

Also Published As

Publication number Publication date
YU268880A (en) 1983-02-28
IT8025538A0 (it) 1980-10-23
DK449780A (da) 1981-04-26
IT1134009B (it) 1986-07-24
JPS5681569A (en) 1981-07-03
AU6351280A (en) 1981-04-30
IL61313A0 (en) 1980-12-31
ES8205207A1 (es) 1981-10-01
FI803294A7 (fi) 1981-04-26
GB2061936A (en) 1981-05-20
PT71939B (en) 1981-08-31
FI803294L (fi) 1981-04-26
ES496210A0 (es) 1981-10-01
PL227421A1 (cs) 1981-06-19
EP0029658A1 (en) 1981-06-03
BE885793A (fr) 1981-04-21
FR2467848A1 (fr) 1981-04-30
US4252954A (en) 1981-02-24
CA1149381A (en) 1983-07-05
GR69994B (cs) 1982-07-23
ZA806437B (en) 1982-05-26
CS212304B2 (en) 1982-03-26
PT71939A (en) 1980-11-01

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