DD208617A5 - Verfahren zur herstellung von substituierten 3-amino-sydnoniminen - Google Patents

Verfahren zur herstellung von substituierten 3-amino-sydnoniminen Download PDF

Info

Publication number
DD208617A5
DD208617A5 DD82237741A DD23774182A DD208617A5 DD 208617 A5 DD208617 A5 DD 208617A5 DD 82237741 A DD82237741 A DD 82237741A DD 23774182 A DD23774182 A DD 23774182A DD 208617 A5 DD208617 A5 DD 208617A5
Authority
DD
German Democratic Republic
Prior art keywords
radical
carbon atoms
atoms
acid addition
methyl
Prior art date
Application number
DD82237741A
Other languages
German (de)
English (en)
Inventor
Karl Schoenafinger
Rudi Beyerle
Helmut Bohn
Melitta Just
Piero A Martorana
Rolf-Eberhard Nitz
Original Assignee
Cassella Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cassella Ag filed Critical Cassella Ag
Publication of DD208617A5 publication Critical patent/DD208617A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D271/04—1,2,3-Oxadiazoles; Hydrogenated 1,2,3-oxadiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Furan Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrane Compounds (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Seasonings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Epoxy Compounds (AREA)
DD82237741A 1981-03-02 1982-02-26 Verfahren zur herstellung von substituierten 3-amino-sydnoniminen DD208617A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19813107933 DE3107933A1 (de) 1981-03-02 1981-03-02 Substituierte 3-amino-sydnonimine, verfahren zu ihrer herstellung und ihre verwendung

Publications (1)

Publication Number Publication Date
DD208617A5 true DD208617A5 (de) 1984-04-04

Family

ID=6126174

Family Applications (1)

Application Number Title Priority Date Filing Date
DD82237741A DD208617A5 (de) 1981-03-02 1982-02-26 Verfahren zur herstellung von substituierten 3-amino-sydnoniminen

Country Status (23)

Country Link
US (2) US4436743A (fr)
EP (1) EP0059356B1 (fr)
JP (1) JPS57158768A (fr)
KR (1) KR880001428B1 (fr)
AT (1) ATE13055T1 (fr)
AU (1) AU545292B2 (fr)
CA (1) CA1192905A (fr)
CS (1) CS224645B2 (fr)
DD (1) DD208617A5 (fr)
DE (2) DE3107933A1 (fr)
DK (1) DK149852C (fr)
ES (1) ES8303404A1 (fr)
FI (1) FI820518L (fr)
HU (1) HU190683B (fr)
IL (1) IL65141A (fr)
NO (1) NO820476L (fr)
NZ (1) NZ199862A (fr)
PH (1) PH18696A (fr)
PL (1) PL136818B1 (fr)
PT (1) PT74507B (fr)
RO (1) RO84816B (fr)
SU (1) SU1097197A3 (fr)
ZA (1) ZA821327B (fr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3107933A1 (de) * 1981-03-02 1982-09-16 Cassella Ag, 6000 Frankfurt Substituierte 3-amino-sydnonimine, verfahren zu ihrer herstellung und ihre verwendung
JPS5859977A (ja) * 1981-10-06 1983-04-09 Banyu Pharmaceut Co Ltd 新規なｎ−アシルシドノンイミン誘導体およびその製法
US4517179A (en) * 1983-04-29 1985-05-14 Pennwalt Corporation Rapid dissolving, uniform drug compositions and their preparation
DK243084A (da) * 1983-05-26 1984-11-27 Takeda Chemical Industries Ltd Perkutane farmaceutiske praeparater til udvortes brug
DE3526068A1 (de) * 1985-07-20 1987-01-22 Cassella Ag Substituierte 3-amino-sydnonimine, verfahren zu ihrer herstellung, ihre verwendung und sie enthaltende pharmazeutische praeparate
DE3702083A1 (de) * 1987-01-24 1988-08-04 Cassella Ag Allylmercaptoacetyl-sydnonimine, verfahren zu ihrer herstellung und ihre verwendung
DE3732174A1 (de) * 1987-09-24 1989-04-06 Cassella Ag Substituierte 3-aminosydnonimine, verfahren zu ihrer herstellung und ihre verwendung
US5221680A (en) * 1988-01-14 1993-06-22 Cassella Aktiengesellschaft Substituted 3-aminosydnonimines
FR2627696B1 (fr) * 1988-02-26 1991-09-13 Fournier Innovation Synergie Nouvelle forme galenique du fenofibrate
US5120732A (en) * 1988-06-14 1992-06-09 Cassella Aktiengesellschaft Substituted 3-aminosyndone imines, a process for their preparation and their use
DE4025604A1 (de) * 1990-08-13 1992-02-20 Cassella Ag 3-dicyclohexylamino-sydnonimine, verfahren zu ihrer herstellung und ihre verwendung
DE4028679A1 (de) * 1990-09-10 1992-03-19 Cassella Ag Substituierte 3-aminosydnonimine, verfahren zu ihrer herstellung und ihre verwendung
DE4031373A1 (de) * 1990-10-04 1992-04-09 Cassella Ag 3-piperazino-sydnonimine, verfahren zu ihrer herstellung und ihre verwendung
EP0903346A1 (fr) * 1995-11-06 1999-03-24 Chugai Seiyaku Kabushiki Kaisha Derives d'imine de sydnone
FR2758459B1 (fr) * 1997-01-17 1999-05-07 Pharma Pass Composition pharmaceutique de fenofibrate presentant une biodisponibilite elevee et son procede de preparation
US6531158B1 (en) 2000-08-09 2003-03-11 Impax Laboratories, Inc. Drug delivery system for enhanced bioavailability of hydrophobic active ingredients

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1695897C3 (de) 1966-07-04 1979-02-15 Takeda Chemical Industries Ltd N-Acyl-sydnonimine, deren Salze, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
US3833580A (en) 1966-08-09 1974-09-03 Boehringer Sohn Ingelheim 3-morpholino-n6-cyclohexylcarbonyl sydnonimine
BE788052A (fr) * 1971-08-26 1973-02-26 Science Union & Cie Societe Fr Nouveaux derives de la sydnone imine
US3833589A (en) * 1972-07-31 1974-09-03 Sandoz Ag Substituted sydnonimine nitrate esters
DE2930736A1 (de) * 1979-07-28 1981-02-12 Cassella Ag Pharmakologisch wirksame, substituierte 3-amino-sydnonimine, verfahren zu ihrer herstellung und ihre verwendung
DE3107933A1 (de) * 1981-03-02 1982-09-16 Cassella Ag, 6000 Frankfurt Substituierte 3-amino-sydnonimine, verfahren zu ihrer herstellung und ihre verwendung
JPS5832870A (ja) * 1981-08-24 1983-02-25 Hiroyoshi Hidaka 新規なシドノンイミン誘導体及びその製法
JPS5859977A (ja) * 1981-10-06 1983-04-09 Banyu Pharmaceut Co Ltd 新規なｎ−アシルシドノンイミン誘導体およびその製法

Also Published As

Publication number Publication date
DE3107933A1 (de) 1982-09-16
EP0059356B1 (fr) 1985-05-02
FI820518A7 (fi) 1982-09-03
FI820518L (fi) 1982-09-03
EP0059356A1 (fr) 1982-09-08
SU1097197A3 (ru) 1984-06-07
NO820476L (no) 1982-09-03
CA1192905A (fr) 1985-09-03
PH18696A (en) 1985-09-05
CS224645B2 (en) 1984-01-16
DE3263342D1 (en) 1985-06-05
DK149852C (da) 1987-06-01
US4551454A (en) 1985-11-05
DK149852B (da) 1986-10-13
AU545292B2 (en) 1985-07-11
NZ199862A (en) 1985-04-30
IL65141A0 (en) 1982-05-31
HU190683B (en) 1986-10-28
PL136818B1 (en) 1986-03-31
ZA821327B (en) 1983-01-26
ATE13055T1 (de) 1985-05-15
RO84816A (fr) 1984-08-17
PT74507B (de) 1983-11-08
DK67682A (da) 1982-09-03
PL235274A1 (fr) 1982-10-25
JPS57158768A (en) 1982-09-30
ES510015A0 (es) 1983-02-01
ES8303404A1 (es) 1983-02-01
KR880001428B1 (ko) 1988-08-08
AU8096682A (en) 1982-09-16
RO84816B (ro) 1984-09-30
PT74507A (de) 1982-04-01
KR830009062A (ko) 1983-12-17
IL65141A (en) 1984-10-31
US4436743A (en) 1984-03-13

Similar Documents

Publication Publication Date Title
DD208617A5 (de) Verfahren zur herstellung von substituierten 3-amino-sydnoniminen
EP0023343B1 (fr) 3-Amino-sydnonimines substituées, procédé pour leur synthèse et préparations pharmaceutiques les contenant
EP0210474B1 (fr) Amino-3 sydnonimines substituées, procédé pour leur préparation, leur application et compositions pharmaceutiques les contenant
EP0054872B1 (fr) Oxadiazole-1,2,5 oxydes-2 bis-substitués en position 3 et 4, leur procédé de préparation, et compositions pharmaceutiques les contenant
EP0276710B1 (fr) Allylmercaptoacétylsydnonimines, procédé pour leur préparation et leur application
EP0327808B1 (fr) 3-Aminosydnonimines substituées, procédé pour leur préparation et utilisation
EP0312773B1 (fr) 3-Aminosydnonimines substituées, procédé pour leur préparation et leur utilisation
EP0346694A1 (fr) 3-Aminosydnoneimines substitués, procédé pour leur préparation et leur utilisation
EP0429751B1 (fr) 3-Amino-sydnonimines substituées, procédé pour leur préparation et leur utilisation
EP0406659A1 (fr) 3-aminosydnonimines substituées, procédé pour leur préparation et leur utilisation
DD209195A5 (de) Verfahren zur herstellung von 1,2,5-oxadiazol-3,4-dicarbonsaeurederivaten
EP0367036B1 (fr) 3-Aminosydnonimines substituées, procédé pour leur préparation et leur utilisation
EP0497122A1 (fr) 3-Aminosydnonimines substituées, procédé pour leur préparation et leur utilisation
DE3819914A1 (de) Substituierte 3-aminosydnonimine, verfahren zu ihrer herstellung und ihre verwendung
EP0480241A1 (fr) 3-Pipérazino-sydnonimines, procédé pour leur préparation et leur utilisation
EP0471232A1 (fr) Dicyclohexylamino-3-sydnonimines, leur procédé de préparation et leur utilisation
DE3921460A1 (de) Substituierte 3-aminosydnonimine, verfahren zu ihrer herstellung und ihre verwendung
EP0457199A1 (fr) 3-Aminosydnonimines substituées, procédé pour leur préparation et leur utilisation
DE3939515A1 (de) Substituierte 3-aminosydnonimine, verfahren zu ihrer herstellung und ihre verwendung
DE3939550A1 (de) Substituierte 3-aminosydnonimine, verfahren zu ihrer herstellung und ihre verwendung
DE4216310A1 (de) Salze von 3-(cis-2,6-Dimethylpiperidino)-sydnonimin
EP0475156A1 (fr) Amino-3 sydnonimines substituées, leur procédé de préparation et leur utilisation