DD216933A5 - Verfahren zur herstellung von 5-aminopyrimidin-4-on-verbindungen und ihren salzen - Google Patents

Verfahren zur herstellung von 5-aminopyrimidin-4-on-verbindungen und ihren salzen Download PDF

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Publication number
DD216933A5
DD216933A5 DD84265728A DD26572884A DD216933A5 DD 216933 A5 DD216933 A5 DD 216933A5 DD 84265728 A DD84265728 A DD 84265728A DD 26572884 A DD26572884 A DD 26572884A DD 216933 A5 DD216933 A5 DD 216933A5
Authority
DD
German Democratic Republic
Prior art keywords
group
general formula
compound
compounds
preparation
Prior art date
Application number
DD84265728A
Other languages
German (de)
English (en)
Inventor
Thomas H Brown
David Tuddenham
Original Assignee
Smith Kline French Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smith Kline French Lab filed Critical Smith Kline French Lab
Publication of DD216933A5 publication Critical patent/DD216933A5/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48—Two nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Steroid Compounds (AREA)
DD84265728A 1983-07-29 1984-07-27 Verfahren zur herstellung von 5-aminopyrimidin-4-on-verbindungen und ihren salzen DD216933A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB838320505A GB8320505D0 (en) 1983-07-29 1983-07-29 Chemical compounds

Publications (1)

Publication Number Publication Date
DD216933A5 true DD216933A5 (de) 1985-01-02

Family

ID=10546495

Family Applications (1)

Application Number Title Priority Date Filing Date
DD84265728A DD216933A5 (de) 1983-07-29 1984-07-27 Verfahren zur herstellung von 5-aminopyrimidin-4-on-verbindungen und ihren salzen

Country Status (21)

Country Link
EP (1) EP0134096B1 (cs)
JP (1) JPS6051179A (cs)
KR (1) KR850001174A (cs)
AT (1) ATE40552T1 (cs)
AU (1) AU564650B2 (cs)
CA (1) CA1261831A (cs)
CS (1) CS244448B2 (cs)
DD (1) DD216933A5 (cs)
DE (1) DE3476541D1 (cs)
DK (1) DK368284A (cs)
ES (1) ES8600254A1 (cs)
FI (1) FI842976A7 (cs)
GB (1) GB8320505D0 (cs)
GR (1) GR82226B (cs)
HU (1) HUT34743A (cs)
IL (1) IL72491A0 (cs)
JO (1) JO1327B1 (cs)
NO (1) NO843043L (cs)
PT (1) PT78977B (cs)
ZA (1) ZA845820B (cs)
ZW (1) ZW11584A1 (cs)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4772704A (en) * 1983-09-21 1988-09-20 Bristol-Myers Company 2,5-disubstituted-4(3H)-pyrimidones having histamine H2 -receptor antagonist activity
GB8421427D0 (en) * 1984-08-23 1984-09-26 Smith Kline French Lab Chemical compounds
CN1972914A (zh) 2004-03-31 2007-05-30 詹森药业有限公司 作为组胺h3受体配合体的非咪唑杂环化合物
KR101372941B1 (ko) 2006-05-30 2014-03-14 얀센 파마슈티카 엔.브이. 히스타민 h3 수용체 조절제로서의 치환된 피리딜 아미드 화합물
BRPI0820481A2 (pt) 2007-11-20 2015-06-16 Janssen Pharmaceutica Nv Composotos cicloalquilóxi e heterocicloalquilóxi piridina como moduladores do receptor de h3 de histamina
EP4196793A1 (en) 2020-08-11 2023-06-21 Université de Strasbourg H2 blockers targeting liver macrophages for the prevention and treatment of liver disease and cancer

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN151188B (cs) * 1978-02-13 1983-03-05 Smith Kline French Lab
ZA793443B (en) * 1978-07-26 1980-12-31 Glaxo Group Ltd Heterocyclic derivatives
US4496567A (en) * 1978-11-13 1985-01-29 Smith Kline & French Laboratories Limited Phenyl alkylaminopyrimidones
US4521418A (en) * 1979-02-21 1985-06-04 Smith Kline & French Laboratories Limited Guanidinothiazolyl derivatives
ZW21281A1 (en) * 1980-10-01 1981-11-18 Smith Kline French Lab Amine derivatives
CA1206151A (en) * 1981-12-28 1986-06-17 Richard P. Pioch Pyrimidone anti-ulcer agents

Also Published As

Publication number Publication date
ZW11584A1 (en) 1985-04-17
GR82226B (cs) 1984-12-13
FI842976L (fi) 1985-01-30
HUT34743A (en) 1985-04-28
DE3476541D1 (de) 1989-03-09
EP0134096A3 (en) 1985-12-18
FI842976A7 (fi) 1985-01-30
NO843043L (no) 1985-01-30
EP0134096B1 (en) 1989-02-01
IL72491A0 (en) 1984-11-30
ZA845820B (en) 1985-06-26
ES534620A0 (es) 1985-09-16
ATE40552T1 (de) 1989-02-15
CS244448B2 (en) 1986-07-17
KR850001174A (ko) 1985-03-16
AU3099184A (en) 1985-01-31
CA1261831A (en) 1989-09-26
DK368284A (da) 1985-01-30
CS581084A2 (en) 1985-08-15
GB8320505D0 (en) 1983-09-01
JO1327B1 (en) 1986-11-30
AU564650B2 (en) 1987-08-20
PT78977B (en) 1986-06-05
PT78977A (en) 1984-08-01
ES8600254A1 (es) 1985-09-16
JPS6051179A (ja) 1985-03-22
DK368284D0 (da) 1984-07-27
FI842976A0 (fi) 1984-07-26
EP0134096A2 (en) 1985-03-13

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