DD232697A5 - Verfahren zur herstellung von benzimidazolen - Google Patents

Verfahren zur herstellung von benzimidazolen Download PDF

Info

Publication number
DD232697A5
DD232697A5 DD84271449A DD27144984A DD232697A5 DD 232697 A5 DD232697 A5 DD 232697A5 DD 84271449 A DD84271449 A DD 84271449A DD 27144984 A DD27144984 A DD 27144984A DD 232697 A5 DD232697 A5 DD 232697A5
Authority
DD
German Democratic Republic
Prior art keywords
group
general formula
compound
phenyl
benzimidazole
Prior art date
Application number
DD84271449A
Other languages
German (de)
English (en)
Inventor
Norbert Hauel
Erich Mueller
Volkhard Austel
Joachim Heider
Manfred Reiffen
Willi Diederen
Jacobus C A Van Meel
Original Assignee
���@����������@��k��
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ���@����������@��k�� filed Critical ���@����������@��k��
Publication of DD232697A5 publication Critical patent/DD232697A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/18—Benzimidazoles; Hydrogenated benzimidazoles with aryl radicals directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DD84271449A 1983-12-23 1984-12-21 Verfahren zur herstellung von benzimidazolen DD232697A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3346575A DE3346575A1 (de) 1983-12-23 1983-12-23 Neue benzimidazole, ihre herstellung und diese verbindungen enthaltende arzneimittel

Publications (1)

Publication Number Publication Date
DD232697A5 true DD232697A5 (de) 1986-02-05

Family

ID=6217793

Family Applications (1)

Application Number Title Priority Date Filing Date
DD84271449A DD232697A5 (de) 1983-12-23 1984-12-21 Verfahren zur herstellung von benzimidazolen

Country Status (14)

Country Link
EP (1) EP0148431A1 (fr)
JP (1) JPS60156676A (fr)
KR (1) KR850004467A (fr)
AU (1) AU3704284A (fr)
DD (1) DD232697A5 (fr)
DE (1) DE3346575A1 (fr)
DK (1) DK597484A (fr)
ES (5) ES8601913A1 (fr)
FI (1) FI845084L (fr)
HU (1) HU193073B (fr)
IL (1) IL73897A0 (fr)
NO (1) NO845169L (fr)
PT (1) PT79718B (fr)
ZA (1) ZA849972B (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LU85544A1 (fr) * 1984-09-19 1986-04-03 Cird Derives heterocycliques aromatiques,leur procede de preparation et leur application dans les domaines therapeutique et cosmetique
DE3522230A1 (de) * 1985-06-21 1987-01-02 Thomae Gmbh Dr K Neue 2-arylimidazole, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
FR2677020B1 (fr) * 1991-05-31 1993-08-27 Cird Galderma Composes derives de benzimidazole, leur procede de preparation et leur utilisation dans les domaines therapeutique et cosmetique.
US5821258A (en) * 1994-12-27 1998-10-13 Mitsui Chemicals, Inc. Phenylbenzimidazole derivatives
EP0841924B1 (fr) * 1995-08-02 2002-10-02 Newcastle University Ventures Limited Composes benzimidazole
US5942532A (en) * 1997-09-05 1999-08-24 Ortho Pharmaceutical Corporation 2-substituted phenyl-benzimidazole antibacterial agents
ATE369854T1 (de) 2001-10-19 2007-09-15 Ortho Mcneil Pharm Inc 2-phenyl benzimidazole und imidazo-[4,5]-pyridine als cds1/chk2-inhibitoren und adjuvantien in der chemotherapie oder strahlungstherapie zur behandlung von krebs
US7622592B2 (en) * 2002-11-01 2009-11-24 Merck & Co., Inc. Carbonylamino-benzimidazole derivatives as androgen receptor modulators
US7132440B2 (en) 2003-04-17 2006-11-07 Janssen Pharmaceutica, N.V. Substituted benzimidazoles and imidazo-[4,5]-pyridines
ES2362102T3 (es) 2004-06-30 2011-06-28 Janssen Pharmaceutica Nv Eteres de bencimidazol e imidazopiridina sustituidos con arilo como agentes anticáncer.
EP3006429B1 (fr) 2010-12-24 2019-02-06 Sumitomo Chemical Co., Ltd. Composé hétérocyclique condensé et son utilisation pour la lutte antiparasitaire

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH350763A (de) * 1958-10-14 1960-12-15 Ciba Geigy Verwendung von Azolverbindungen als Schutzmittel gegen ultraviolette Strahlung
DE1447733B2 (de) * 1963-12-23 1977-04-21 Hoechst Ag, 6000 Frankfurt 2-(3,5-dihydroxyphenyl)-benzimidazolderivate
IL23847A (en) * 1964-08-07 1969-02-27 Merck & Co Inc Benzimidazoles useful as antifungals
FR1569337A (fr) * 1968-06-18 1969-05-30
DE2742093A1 (de) * 1977-09-19 1979-03-29 Cassella Ag Verfahren zur herstellung von 2-(3'- bzw. 4'-aminophenyl)-5(bzw. 6) -aminobenzimidazolen
DE2927987A1 (de) * 1979-07-11 1981-02-05 Thomae Gmbh Dr K Neue 2-alkoxyphenyl-imidazo eckige klammer auf 4,5-b eckige klammer zu pyridine, deren herstellung und deren verwendung als arzneimittel
DE3224512A1 (de) * 1982-07-01 1984-01-05 Dr. Karl Thomae Gmbh, 7950 Biberach Neue imidazolderivate, ihre herstellung und diese verbindungen enthaltende arzneimittel

Also Published As

Publication number Publication date
ES8604162A1 (es) 1986-01-16
DK597484A (da) 1985-06-24
ES544118A0 (es) 1986-01-16
DK597484D0 (da) 1984-12-13
PT79718A (de) 1985-01-01
DE3346575A1 (de) 1985-07-04
ES544119A0 (es) 1986-01-16
ES544116A0 (es) 1986-01-16
HUT37763A (en) 1986-02-28
ES538929A0 (es) 1985-11-16
PT79718B (de) 1986-12-30
AU3704284A (en) 1985-07-04
ES544117A0 (es) 1986-01-16
KR850004467A (ko) 1985-07-15
ES8604165A1 (es) 1986-01-16
ES8604164A1 (es) 1986-01-16
EP0148431A1 (fr) 1985-07-17
NO845169L (no) 1985-06-24
ZA849972B (en) 1986-08-27
IL73897A0 (en) 1985-03-31
FI845084A7 (fi) 1985-06-24
HU193073B (en) 1987-08-28
ES8601913A1 (es) 1985-11-16
FI845084L (fi) 1985-06-24
FI845084A0 (fi) 1984-12-21
JPS60156676A (ja) 1985-08-16
ES8604163A1 (es) 1986-01-16

Similar Documents

Publication Publication Date Title
EP0008391B1 (fr) Benzimidazoles, leur préparation et médicaments les contenant
DE59209330C5 (de) Benzimidazole, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung
DE3224512A1 (de) Neue imidazolderivate, ihre herstellung und diese verbindungen enthaltende arzneimittel
DE3522230A1 (de) Neue 2-arylimidazole, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
DE4031287A1 (de) Benzimidazole, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
DE2837161A1 (de) Neue benzimidazole und deren verwendung
EP0263352A1 (fr) Imidazo-benzoxazinones, leur préparation et médicaments contenant ces composés
DE2927988A1 (de) Neue 8-phenyl-purine, deren herstellung und deren verwendung als arzneimittel
EP0130461A2 (fr) Imidazoles, leur préparation et médicaments contenant ces composés
DE2720085C2 (fr)
DD232697A5 (de) Verfahren zur herstellung von benzimidazolen
EP0581166A1 (fr) Benzimidazoles, procédé pour leur préparation et leur utilisation comme antagonists de l'angiotensine-II
WO2004014894A1 (fr) Nouveaux promedicaments de 1-methyl-2(4-amidinophenylaminomethyl)-benzimidazol-5-yl-acide carboxylique-(n-2-pyridil-n-2-hydroxycarbonylethyl)-amide, leur preparation et leur utilisation en tant que medicaments
DE2427943C2 (de) Benzimidazole, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel
DE2052719A1 (de) Verfahren zur Herstellung von neuen 5 Nitrofuryldenvaten
EP0543263A2 (fr) Benzimidazoles, médicaments les contenant et procédé pour leur préparation
EP0184738A2 (fr) Dérivés d'imidazole, médicaments contenant ces composés et procédé pour leur préparation
DE3346640A1 (de) Neue imidazolderivate, deren herstellung und diese verbindungen enthaltende arzneimittel
EP0138034B1 (fr) Pyrido[1,2-c]imidazo[1,2-a]benzimidazoles substitués, procédé pour leur préparation, leur application et compositions pharmaceutiques à base de ces composés
EP0360784A1 (fr) Dérivés de thiényloxy-alcoylamine, procédé de préparation et médicaments contenant ces composés
EP0078949B1 (fr) 1-Furyl-3,4-dihydroisoquinoléines, procédé pour leur préparation, leur utilisation et médicaments les contenant
EP0006451B1 (fr) Imidazo (1,2-a) imidazoles, leurs sels d'addition acides, médicaments les contenant et procédé pour leur préparation
EP0037471B1 (fr) 1-Aroyl-2-phénylamino-2-imidazolines, leur préparation et leurs compositions pharmaceutiques
DE3346602A1 (de) Neue imidazo(4,5-c)pyridin-one, deren herstellung und diese verbindungen enthaltende arzneimittel
DE2428640A1 (de) Anthelmintische verbindungen und verfahren zu ihrer herstellung