DD237611A5 - Verfahren zur herstellung einer waessrigen ueberzugsmitteldispersion und ihre verwendung zum ueberziehen von arzneimittel - Google Patents

Verfahren zur herstellung einer waessrigen ueberzugsmitteldispersion und ihre verwendung zum ueberziehen von arzneimittel Download PDF

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Publication number
DD237611A5
DD237611A5 DD85281842A DD28184285A DD237611A5 DD 237611 A5 DD237611 A5 DD 237611A5 DD 85281842 A DD85281842 A DD 85281842A DD 28184285 A DD28184285 A DD 28184285A DD 237611 A5 DD237611 A5 DD 237611A5
Authority
DD
German Democratic Republic
Prior art keywords
dispersion
copolymer
water
film
weight
Prior art date
Application number
DD85281842A
Other languages
German (de)
English (en)
Inventor
Klaus Lehmann
Dieter Dreher
Wolfgang Weisbrod
Original Assignee
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Application filed by ��������@��������@����������@���k�� filed Critical ��������@��������@����������@���k��
Publication of DD237611A5 publication Critical patent/DD237611A5/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J3/00—Processes of treating or compounding macromolecular substances
    • C08J3/02—Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques
    • C08J3/03—Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques in aqueous media
    • C08J3/05—Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques in aqueous media from solid polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1611—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A61K9/2846—Poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7007—Drug-containing films, membranes or sheets
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2357/00—Characterised by the use of unspecified polymers obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • C08J2357/04—Copolymers in which only the monomer in minority is defined

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Paints Or Removers (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DD85281842A 1984-10-19 1985-10-17 Verfahren zur herstellung einer waessrigen ueberzugsmitteldispersion und ihre verwendung zum ueberziehen von arzneimittel DD237611A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3438291A DE3438291A1 (de) 1984-10-19 1984-10-19 Verfahren zur herstellung einer waessrigen ueberzugsmitteldispersion und ihre verwendung zum ueberziehen von arzneimitteln

Publications (1)

Publication Number Publication Date
DD237611A5 true DD237611A5 (de) 1986-07-23

Family

ID=6248261

Family Applications (1)

Application Number Title Priority Date Filing Date
DD85281842A DD237611A5 (de) 1984-10-19 1985-10-17 Verfahren zur herstellung einer waessrigen ueberzugsmitteldispersion und ihre verwendung zum ueberziehen von arzneimittel

Country Status (8)

Country Link
US (1) US4737357A (cs)
EP (1) EP0181515B1 (cs)
JP (1) JPH0764756B2 (cs)
AT (1) ATE56143T1 (cs)
CS (1) CS262424B2 (cs)
DD (1) DD237611A5 (cs)
DE (2) DE3438291A1 (cs)
HU (1) HU195109B (cs)

Families Citing this family (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0662779B2 (ja) * 1986-11-11 1994-08-17 住友化学工業株式会社 カチオン性ポリマーの水分散液およびその用途
DE3773189D1 (de) * 1987-03-25 1991-10-24 Sekisui Chemical Co Ltd Harz zur anwendung bei magnetischen aufzeichnungstraegern und verfahren zu seiner herstellung.
DE3723668A1 (de) * 1987-07-17 1989-01-26 Roehm Gmbh Staubarmes spruehgetrocknetes emulsionspolymerisat und verfahren zu seiner herstellung und anwendung
DE3920082A1 (de) * 1989-06-20 1991-03-07 Roehm Gmbh Filmbildendes waessriges ueberzugsmittel fuer feste arzneimittel, verfahren zu seiner herstellung und verwendung
US5028676A (en) * 1989-06-26 1991-07-02 Sekisui Kagaku Kogyo Kabushiki Kaisha Resin for magnetic recording media from vinyl chloride with quanternary and phosphoric monomers
JPH0674206B2 (ja) * 1989-12-28 1994-09-21 田辺製薬株式会社 放出制御型製剤およびその製法
DE4133192A1 (de) * 1991-10-07 1993-04-08 Basf Ag Verfahren zum ueberziehen von arzneiformen
DE4220782A1 (de) * 1992-06-25 1994-01-05 Basf Ag Verfahren zur Herstellung von festen pharmazeutischen Retardformen
HU213407B (en) * 1993-12-09 1997-06-30 Egyt Gyogyszervegyeszeti Gyar Process for producing tablet with diffusive-osmotic release
DE4405156C1 (de) * 1994-02-18 1995-10-26 Univ Karlsruhe Verfahren zur Herstellung beschichteter polymerer Mikropartikel
US6165988A (en) * 1995-02-10 2000-12-26 Christian Noe Medicament in particulate form
DE19653605C2 (de) * 1996-12-20 2002-11-28 Roehm Gmbh Haft- und Bindemittel für dermale oder transdermale Therapiesysteme und dessen Verwendung zur Herstellung eines transdermalen Therapiesystems
DE19918435A1 (de) * 1998-07-23 2000-01-27 Roehm Gmbh Überzugs- und Bindemittel für orale oder dermale Arzneiformen
BR0013719A (pt) * 1999-09-02 2002-07-23 Nostrum Pharmaceuticals Inc Dosagem oral de liberaçâo controlada, apropriada para administração oral
US20050175687A1 (en) * 2001-01-30 2005-08-11 Mcallister Stephen M. Pharmaceutical formulations
GB0102342D0 (en) * 2001-01-30 2001-03-14 Smithkline Beecham Plc Pharmaceutical formulation
US7883721B2 (en) 2001-01-30 2011-02-08 Smithkline Beecham Limited Pharmaceutical formulation
DE10104880A1 (de) * 2001-01-31 2002-08-08 Roehm Gmbh Multipartikuläre Arzneiform, enthaltend mindestens zwei unterschiedlich überzogene Pelletformen
DE10127134A1 (de) * 2001-06-05 2002-12-12 Roehm Gmbh verfahren zur Herstellung von Formkörpern aus (Meth)acrylat-Copolymeren mittels Spritzguß
US7772138B2 (en) 2002-05-21 2010-08-10 Kimberly-Clark Worldwide, Inc. Ion sensitive, water-dispersible polymers, a method of making same and items using same
US20040058600A1 (en) * 2002-09-20 2004-03-25 Bunyard W. Clayton Water-dispersible, cationic polymers, a method of making same and items using same
US6994865B2 (en) * 2002-09-20 2006-02-07 Kimberly-Clark Worldwide, Inc. Ion triggerable, cationic polymers, a method of making same and items using same
US7101456B2 (en) * 2002-09-20 2006-09-05 Kimberly-Clark Worldwide, Inc. Ion triggerable, cationic polymers, a method of making same and items using same
US7157389B2 (en) * 2002-09-20 2007-01-02 Kimberly-Clark Worldwide, Inc. Ion triggerable, cationic polymers, a method of making same and items using same
US6960371B2 (en) * 2002-09-20 2005-11-01 Kimberly-Clark Worldwide, Inc. Water-dispersible, cationic polymers, a method of making same and items using same
US7141519B2 (en) * 2002-09-20 2006-11-28 Kimberly-Clark Worldwide, Inc. Ion triggerable, cationic polymers, a method of making same and items using same
DE10250543A1 (de) * 2002-10-29 2004-05-19 Röhm GmbH & Co. KG Mehrschichtige Arzneiform
US20070010573A1 (en) * 2003-06-23 2007-01-11 Xianqi Kong Methods and compositions for treating amyloid-related diseases
US7244764B2 (en) * 2003-06-23 2007-07-17 Neurochem (International) Limited Methods and compositions for treating amyloid-related diseases
US7414076B2 (en) * 2003-06-23 2008-08-19 Neurochem (International) Limited Methods and compositions for treating amyloid-related diseases
TW200526274A (en) 2003-07-21 2005-08-16 Smithkline Beecham Plc Pharmaceutical formulations
US20070154550A1 (en) * 2003-08-28 2007-07-05 Potdar Arti Pharmaceutical composition comprising anticonvulsant with taste mask coating
GB0403247D0 (en) 2004-02-13 2004-03-17 Tillotts Pharma Ag A pharmaceutical composition
PE20060003A1 (es) * 2004-03-12 2006-03-01 Smithkline Beecham Plc Formulacion farmaceutica polimerica para moldear por inyeccion
BRPI0517790A (pt) * 2004-11-12 2008-10-21 Neurochem Int Ltd métodos e composições fluoradas para tratar doenças relacionadas à amilóide
CA2586334A1 (en) * 2004-11-16 2006-06-08 Neurochem (International) Limited Compounds for the treatment of cns and amyloid associated diseases
WO2006085149A2 (en) 2004-12-22 2006-08-17 Neurochem (International) Limited Methods and compositions for treating amyloid-related diseases
KR101608445B1 (ko) 2006-10-12 2016-04-01 비에이치아이 리미티드 파트너쉽 3-아미노-1-프로판설폰산을 전달하기 위한 방법, 화합물, 조성물 및 비히클
DE102007009242A1 (de) 2007-02-22 2008-09-18 Evonik Röhm Gmbh Pellets mit magensaftresistenter Wirkstoff-Matix
DE102007009243A1 (de) 2007-02-22 2008-09-18 Evonik Röhm Gmbh Pellets mit einer Wirkstoff-Matrix und einem Polymerüberzug, sowie ein Verfahren zur Herstellung der Pellets
WO2009150228A2 (en) * 2008-06-13 2009-12-17 Glaxo Group Limited Pharmaceutical formulations
EP2501368B1 (en) 2009-11-16 2018-04-18 Evonik Röhm GmbH A process for converting a solid (meth)acrylate copolymer into a dispersed form by means of a dispersing agent
MX341163B (es) * 2010-10-13 2016-08-10 Evonik Roehm Gmbh Proceso para preparar un copolimero de (met)acrilato que contiene grupos amino terciarios por polimerizacion por radicales libres en solucion.
US20150250888A1 (en) 2012-09-28 2015-09-10 Evonik Industries Ag Process for preparing aqueous dispersions
WO2014108192A1 (en) 2013-01-10 2014-07-17 Evonik Industries Ag Electronic device unit being equipped on the outside with a coating layer comprising a cationic (meth)acrylate copolymer
KR20200057019A (ko) 2017-09-14 2020-05-25 에보닉 오퍼레이션스 게엠베하 서방성 및 에탄올의 영향에 대한 내성을 갖는 중합체 및 투여 형태
JP2021515778A (ja) 2018-03-09 2021-06-24 エボニック オペレーションズ ゲーエムベーハー エタノールの影響に対する耐性を有するポリマー混合物

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3287305A (en) * 1953-10-30 1966-11-22 Ciba Ltd Cationactive dispersions of finely divided water-insoluble cationactive polymers containing quaternary ammonium groups
AT270071B (de) * 1966-08-12 1969-04-10 Roehm & Haas Gmbh Dragierlack für Arzneiformen
US4077930A (en) * 1974-07-16 1978-03-07 Calgon Corporation Self-inverting emulsions of dialkyldiallyl ammonium chloride polymers and copolymers
JPS53149292A (en) * 1977-05-31 1978-12-26 Sumitomo Chem Co Ltd High-polymer ampholyte, its production and paper-strengthening agent and high-polymer coagulant containing the same as major ingredient
US4305860A (en) * 1980-08-21 1981-12-15 National Starch And Chemical Corporation Stable, pumpable, solvent-free colloidal polyampholyte latices, their preparation and use in paper
DE3106449A1 (de) * 1981-02-20 1982-09-09 Röhm GmbH, 6100 Darmstadt "in magensaft loesliche oder quellbare ueberzugsmasse und ihre verwendung in einem verfahren zum ueberziehen von arzneiformen"
DE3208791A1 (de) * 1982-03-11 1983-09-22 Röhm GmbH, 6100 Darmstadt Verfahren zum ueberziehen von arzneiformen mittes eines in wasser dispergierten ueberzugsmittels
US4444954A (en) * 1982-09-30 1984-04-24 The Sherwin-Williams Company Water reducible quaternary ammonium salt containing polymers
US4444955A (en) * 1982-09-30 1984-04-24 The Sherwin-Williams Company Water reducible quaternary ammonium salt containing polymers
US4548981A (en) * 1983-07-01 1985-10-22 Polaroid Corporation Compositions and articles containing polymeric vinyl aromatic aminimides
US4617362A (en) * 1984-12-31 1986-10-14 Allied Corporation Inverse emulsion polymers with improved incorporation of diallyldimethylammonium chloride

Also Published As

Publication number Publication date
DE3438291A1 (de) 1986-04-24
ATE56143T1 (de) 1990-09-15
HUT38535A (en) 1986-06-30
JPS61100527A (ja) 1986-05-19
CS262424B2 (en) 1989-03-14
HU195109B (en) 1988-04-28
CS732085A2 (en) 1988-07-15
EP0181515A2 (de) 1986-05-21
EP0181515A3 (en) 1987-08-19
US4737357A (en) 1988-04-12
DE3579558D1 (de) 1990-10-11
EP0181515B1 (de) 1990-09-05
JPH0764756B2 (ja) 1995-07-12

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ENJ Ceased due to non-payment of renewal fee