DD273256A5 - Verfahren zur herstellung von 3-amino-dihydro-[1]benzopyrane und benzothiopyrane - Google Patents

Verfahren zur herstellung von 3-amino-dihydro-[1]benzopyrane und benzothiopyrane Download PDF

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Publication number
DD273256A5
DD273256A5 DD88313194A DD31319488A DD273256A5 DD 273256 A5 DD273256 A5 DD 273256A5 DD 88313194 A DD88313194 A DD 88313194A DD 31319488 A DD31319488 A DD 31319488A DD 273256 A5 DD273256 A5 DD 273256A5
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DD
German Democratic Republic
Prior art keywords
formula
compound
hydroxy
hydrogen
compounds
Prior art date
Application number
DD88313194A
Other languages
German (de)
English (en)
Inventor
Alan J Hutchison
Original Assignee
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Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Application filed by ����`��@���k�� filed Critical ����`��@���k��
Publication of DD273256A5 publication Critical patent/DD273256A5/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
    • C07D335/04—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D335/06—Benzothiopyrans; Hydrogenated benzothiopyrans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pyrane Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Cephalosporin Compounds (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
DD88313194A 1987-02-27 1988-02-25 Verfahren zur herstellung von 3-amino-dihydro-[1]benzopyrane und benzothiopyrane DD273256A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/020,054 US4801605A (en) 1986-08-29 1987-02-27 3-amino-dihydro-[1]-benzopyrans and benzothiopyrans

Publications (1)

Publication Number Publication Date
DD273256A5 true DD273256A5 (de) 1989-11-08

Family

ID=21796497

Family Applications (1)

Application Number Title Priority Date Filing Date
DD88313194A DD273256A5 (de) 1987-02-27 1988-02-25 Verfahren zur herstellung von 3-amino-dihydro-[1]benzopyrane und benzothiopyrane

Country Status (20)

Country Link
US (1) US4801605A (da)
EP (1) EP0280269B1 (da)
JP (1) JPS63277671A (da)
KR (1) KR880009953A (da)
AT (1) ATE72563T1 (da)
AU (1) AU612625B2 (da)
DD (1) DD273256A5 (da)
DE (1) DE3868329D1 (da)
DK (1) DK100588A (da)
ES (1) ES2038707T3 (da)
FI (1) FI880866A7 (da)
GR (1) GR3003800T3 (da)
HU (1) HU201920B (da)
IL (1) IL85494A0 (da)
NO (1) NO880843L (da)
NZ (1) NZ223647A (da)
PH (1) PH23479A (da)
PT (1) PT86830B (da)
YU (1) YU36688A (da)
ZA (1) ZA881375B (da)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2673024B2 (ja) * 1988-01-15 1997-11-05 アボツト・ラボラトリーズ アミノメチル‐クロマン及び‐チオクロマン化合物
EP0389425B1 (de) * 1989-03-22 1995-04-26 Ciba-Geigy Ag Neue Benzothiopyranylamine
US5306830A (en) * 1989-04-27 1994-04-26 The Upjohn Company Substituted 3-amino chromans
AU627027B2 (en) * 1989-04-27 1992-08-13 Pharmacia & Upjohn Company Substituted 3-amino chromans
US5155130A (en) * 1989-08-11 1992-10-13 Ciba-Geigy Corporation Certain benzopyran and benzothiopyran derivatives
SE8904361D0 (sv) * 1989-12-22 1989-12-22 Astra Ab New chroman and thiochroman derivatives
US5616610A (en) * 1989-12-22 1997-04-01 Astra Aktiebolag (R)-5-carbamoyl-8-fluoro-3-N,N-disubstituted-amino-3,4-dihydro-2H-1-benzopyrans
US5420151A (en) * 1989-12-22 1995-05-30 Aktiebolaget Astra Chroman derivatives
EP0471515B1 (en) * 1990-08-15 1997-03-05 Eli Lilly And Company Ring-substituted 2-amino-1,2,3,4-tetra-hydronaphthalenes, 3-aminochromanes and 3-aminothiochromanes
US5348973A (en) * 1990-10-09 1994-09-20 Rhone-Poulenc Chimie Resolution of hydroxychroman-2-carboxylic acid esters by enantiomeric hydrolysis
US5120758A (en) * 1991-02-08 1992-06-09 Ciba-Geigy Corporation Certain benzodioxole, benzodioxane and benzodioxepin derivatives useful as 5-lipoxygenase inhibitors
IL114760A (en) * 1991-02-08 1997-11-20 Lilly Co Eli Ring-substituted-2-amino-1,2,3,4-tetrahydronaphthalenes and 3-aminochromanes intermediates thereto
DE4128690A1 (de) * 1991-08-29 1993-03-04 Boehringer Mannheim Gmbh Bicyclische sulfone, verfahren zu ihrer herstellung und diese enthaltende arzneimittel
HRP920935A2 (en) * 1991-10-08 1995-08-31 Astra Ab New therapeutically active compound
US5478857A (en) * 1993-12-23 1995-12-26 Eli Lilly And Company Use of PLA2 inhibitors as treatment for alzheimer's disease
IT1271009B (it) * 1994-09-13 1997-05-26 Zambon Spa Derivati del benzopirano e del benzotiopirano attivi sul sistema cardiovascolare
SE9701438D0 (sv) * 1997-04-17 1997-04-17 Astra Ab A new process
GB9801812D0 (en) 1998-01-29 1998-03-25 Zeneca Ltd Chemical compounds
GB0426061D0 (en) * 2004-11-26 2004-12-29 Pfizer Ltd Chroman compounds
EP2236511A4 (en) 2007-12-21 2011-04-13 Alla Chem Llc LIGANDS OF ALPHA ADRENOCEPTORS AND OF DOPAMINE, HISTAMIN, IMIDAZOLIN AND SEROTONIN RECEPTORS AND THEIR APPLICATION THEREOF

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3142682A (en) * 1961-11-21 1964-07-28 Ciba Geigy Corp Tertiary amino derivatives of chromans and homo-chromans
GB1086101A (en) * 1965-01-19 1967-10-04 Ciba Ltd New chromans and process for preparing same
US3607886A (en) * 1969-04-24 1971-09-21 Parke Davis & Co Chromanamines
US3629289A (en) * 1969-04-24 1971-12-21 Parke Davis & Co Chromanamines
JPS561305B2 (da) * 1972-12-18 1981-01-13
US4062870A (en) * 1974-05-31 1977-12-13 Beecham Group Limited Chroman derivatives
US4013771A (en) * 1975-12-15 1977-03-22 Warner-Lambert Company Substituted 2-aminothiochromones
LU79077A1 (de) * 1978-02-16 1979-09-06 Ciba Geigy Ag Verfahren zur herstellung neuer benzothiopyranderivate
US4203895A (en) * 1978-04-14 1980-05-20 Warner-Lambert Company Process for the preparation of cis-(±)-3,4-dihydro-N,N,2-trimethyl-2H-1-benzopyran-3-amine and intermediates produced thereby
US4232953A (en) * 1979-06-27 1980-11-11 Alvarez Sabater Fernando Gravity-feed rotary tray slide projector
IT1226045B (it) * 1981-07-29 1990-12-10 Simes Derivati tetraidrochinolici
ATE23718T1 (de) * 1981-09-25 1986-12-15 Beecham Group Plc Benzopyran-verbindungen mit pharmazeutischer wirkung.
FI79535C (fi) * 1982-05-06 1990-01-10 Erba Farmitalia Foerfarande foer framstaellning av dihydrobensopyrans och dihydrobensotiopyrans substituerade iminoderivat.
US4500545A (en) * 1982-11-16 1985-02-19 Eli Lilly And Company Hydroxyaminotetralincarboxamides
JPS59110690A (ja) * 1982-12-16 1984-06-26 Dai Ichi Seiyaku Co Ltd ベンゾピラン誘導体
US4657925A (en) * 1984-08-13 1987-04-14 Nelson Research & Development Co. Method and compositions for reducing the intraocular pressure of mammals
DE3583307D1 (en) * 1984-05-10 1991-08-01 Ciba Geigy Ag Benzo-(pyrano und thiopyrano)-pyridine.
US4736031A (en) * 1985-06-10 1988-04-05 Takeda Chemical Industries, Ltd. 2-(piperazinylalkyl)-1-benzothiepin, 1-benzoxepin, and 1,5-benzodioxepin derivatives
PH22522A (en) * 1985-09-03 1988-10-17 Ciba Geigy Ag 3-amino-dihydro-1-benzopyrans and benzothiopyrans, their pharmaceutical compositions and method of using said compounds
SE8605504D0 (sv) * 1986-12-19 1986-12-19 Astra Laekemedel Ab Novel chroman derivatives

Also Published As

Publication number Publication date
ES2038707T3 (es) 1993-08-01
US4801605A (en) 1989-01-31
NO880843L (no) 1988-08-29
DE3868329D1 (de) 1992-03-26
PH23479A (en) 1989-08-07
PT86830A (pt) 1988-03-01
FI880866A0 (fi) 1988-02-24
NO880843D0 (no) 1988-02-26
IL85494A0 (en) 1988-07-31
DK100588D0 (da) 1988-02-26
ATE72563T1 (de) 1992-02-15
HU201920B (en) 1991-01-28
KR880009953A (ko) 1988-10-06
PT86830B (pt) 1992-05-29
AU612625B2 (en) 1991-07-18
NZ223647A (en) 1991-06-25
JPS63277671A (ja) 1988-11-15
DK100588A (da) 1988-08-28
ZA881375B (en) 1988-08-29
YU36688A (en) 1990-04-30
EP0280269A1 (de) 1988-08-31
AU1234788A (en) 1988-09-01
GR3003800T3 (da) 1993-03-16
EP0280269B1 (de) 1992-02-12
FI880866A7 (fi) 1988-08-28

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