PT86830A - Process for preparing 3-amino-di-hydro-]1"-benzopyrans and benzothiopyrans and benzothiopyrans - Google Patents

Process for preparing 3-amino-di-hydro-]1"-benzopyrans and benzothiopyrans and benzothiopyrans

Info

Publication number: PT86830A
Authority: PT; Portugal
Prior art keywords: compounds; lower alkyl; denotes; aryl; benzothiopyrans
Prior art date: 1987-02-27

Application number

PT86830A

Other languages

English (en)

Other versions

PT86830B (pt

Inventor

Alan J Hutchison

Original Assignee

Ciba Geigy Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-02-27

Filing date

1988-02-25

Publication date

1988-03-01

1988-02-25 Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag

1988-03-01 Publication of PT86830A publication Critical patent/PT86830A/pt

1992-05-29 Publication of PT86830B publication Critical patent/PT86830B/pt

Links

238000004519 manufacturing process Methods 0.000 title 1
125000000217 alkyl group Chemical group 0.000 abstract 6
150000001875 compounds Chemical class 0.000 abstract 6
229910052739 hydrogen Inorganic materials 0.000 abstract 5
239000001257 hydrogen Substances 0.000 abstract 5
125000003545 alkoxy group Chemical group 0.000 abstract 4
150000002431 hydrogen Chemical class 0.000 abstract 4
NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 3
239000005864 Sulphur Substances 0.000 abstract 3
QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 3
229910052760 oxygen Inorganic materials 0.000 abstract 3
239000001301 oxygen Substances 0.000 abstract 3
125000004423 acyloxy group Chemical group 0.000 abstract 2
125000004104 aryloxy group Chemical group 0.000 abstract 2
210000003169 central nervous system Anatomy 0.000 abstract 2
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
125000002947 alkylene group Chemical group 0.000 abstract 1
125000004432 carbon atom Chemical group C* 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
208000035475 disorder Diseases 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
150000002367 halogens Chemical class 0.000 abstract 1
102000005962 receptors Human genes 0.000 abstract 1
108020003175 receptors Proteins 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
229940121356 serotonin receptor antagonist Drugs 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
- C07D335/04—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D335/06—Benzothiopyrans; Hydrogenated benzothiopyrans
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Neurology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Biomedical Technology (AREA)
Pharmacology & Pharmacy (AREA)
Neurosurgery (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Psychiatry (AREA)
Anesthesiology (AREA)
Pain & Pain Management (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Pyrane Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Cephalosporin Compounds (AREA)
Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)

PT86830A 1987-02-27 1988-02-25 Processo para a preparacao de 3-amino-di-hidro-{1}-benzo-piranos e benzotiopiranos PT86830B (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US07/020,054 US4801605A (en)	1986-08-29	1987-02-27	3-amino-dihydro-[1]-benzopyrans and benzothiopyrans

Publications (2)

Publication Number	Publication Date
PT86830A true PT86830A (pt)	1988-03-01
PT86830B PT86830B (pt)	1992-05-29

Family

ID=21796497

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT86830A PT86830B (pt)	1987-02-27	1988-02-25	Processo para a preparacao de 3-amino-di-hidro-{1}-benzo-piranos e benzotiopiranos

Country Status (20)

Country	Link
US (1)	US4801605A (pt)
EP (1)	EP0280269B1 (pt)
JP (1)	JPS63277671A (pt)
KR (1)	KR880009953A (pt)
AT (1)	ATE72563T1 (pt)
AU (1)	AU612625B2 (pt)
DD (1)	DD273256A5 (pt)
DE (1)	DE3868329D1 (pt)
DK (1)	DK100588A (pt)
ES (1)	ES2038707T3 (pt)
FI (1)	FI880866A7 (pt)
GR (1)	GR3003800T3 (pt)
HU (1)	HU201920B (pt)
IL (1)	IL85494A0 (pt)
NO (1)	NO880843L (pt)
NZ (1)	NZ223647A (pt)
PH (1)	PH23479A (pt)
PT (1)	PT86830B (pt)
YU (1)	YU36688A (pt)
ZA (1)	ZA881375B (pt)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE68908392T2 (de) *	1988-01-15	1994-02-10	Abbott Lab	Aminomethyl-chroman- und -thiochroman-verbindungen.
DE69018864D1 (de) *	1989-03-22	1995-06-01	Ciba Geigy Ag	Neue Benzothiopyranylamine.
CA2047236C (en) *	1989-04-27	1997-07-22	Bengt Ronny Andersson	Substituted 3-amino chromans
US5306830A (en) *	1989-04-27	1994-04-26	The Upjohn Company	Substituted 3-amino chromans
US5155130A (en) *	1989-08-11	1992-10-13	Ciba-Geigy Corporation	Certain benzopyran and benzothiopyran derivatives
SE8904361D0 (sv) *	1989-12-22	1989-12-22	Astra Ab	New chroman and thiochroman derivatives
US5616610A (en) *	1989-12-22	1997-04-01	Astra Aktiebolag	(R)-5-carbamoyl-8-fluoro-3-N,N-disubstituted-amino-3,4-dihydro-2H-1-benzopyrans
US5420151A (en) *	1989-12-22	1995-05-30	Aktiebolaget Astra	Chroman derivatives
ATE149480T1 (de) *	1990-08-15	1997-03-15	Lilly Co Eli	Ring-substituierte 2-amino-1,2,3,4-tetra- hydronaphthaline, 3-aminochromane und 3- aminothiochromane
US5348973A (en) *	1990-10-09	1994-09-20	Rhone-Poulenc Chimie	Resolution of hydroxychroman-2-carboxylic acid esters by enantiomeric hydrolysis
NZ241495A (en) *	1991-02-08	1994-10-26	Lilly Co Eli	2-amino-1,2,3,4-tetrahydronaphthalene and 3-aminochromane derivative, preparation and pharmaceutical compositions thereof
US5120758A (en) *	1991-02-08	1992-06-09	Ciba-Geigy Corporation	Certain benzodioxole, benzodioxane and benzodioxepin derivatives useful as 5-lipoxygenase inhibitors
DE4128690A1 (de) *	1991-08-29	1993-03-04	Boehringer Mannheim Gmbh	Bicyclische sulfone, verfahren zu ihrer herstellung und diese enthaltende arzneimittel
HRP920935A2 (en) *	1991-10-08	1995-08-31	Astra Ab	New therapeutically active compound
US5478857A (en) *	1993-12-23	1995-12-26	Eli Lilly And Company	Use of PLA2 inhibitors as treatment for alzheimer's disease
IT1271009B (it) *	1994-09-13	1997-05-26	Zambon Spa	Derivati del benzopirano e del benzotiopirano attivi sul sistema cardiovascolare
SE9701438D0 (sv) *	1997-04-17	1997-04-17	Astra Ab	A new process
GB9801812D0 (en)	1998-01-29	1998-03-25	Zeneca Ltd	Chemical compounds
GB0426061D0 (en) *	2004-11-26	2004-12-29	Pfizer Ltd	Chroman compounds
WO2009082268A2 (ru)	2007-12-21	2009-07-02	Alla Chem, Llc	ЛИГАНДЫ α-АДРЕНОЦЕПТОРОВ, ДОПАМИНОВЫХ, ГИСТАМИНОВЫХ, ИМИДАЗОЛИНОВЫХ И СЕРОТОНИНОВЫХ РЕЦЕПТОРОВ И ИХ ПРИМЕНЕНИЕ

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3142682A (en) *	1961-11-21	1964-07-28	Ciba Geigy Corp	Tertiary amino derivatives of chromans and homo-chromans
GB1086101A (en) *	1965-01-19	1967-10-04	Ciba Ltd	New chromans and process for preparing same
US3629289A (en) *	1969-04-24	1971-12-21	Parke Davis & Co	Chromanamines
US3607886A (en) *	1969-04-24	1971-09-21	Parke Davis & Co	Chromanamines
JPS561305B2 (pt) *	1972-12-18	1981-01-13
US4062870A (en) *	1974-05-31	1977-12-13	Beecham Group Limited	Chroman derivatives
US4013771A (en) *	1975-12-15	1977-03-22	Warner-Lambert Company	Substituted 2-aminothiochromones
LU79077A1 (de) *	1978-02-16	1979-09-06	Ciba Geigy Ag	Verfahren zur herstellung neuer benzothiopyranderivate
US4203895A (en) *	1978-04-14	1980-05-20	Warner-Lambert Company	Process for the preparation of cis-(±)-3,4-dihydro-N,N,2-trimethyl-2H-1-benzopyran-3-amine and intermediates produced thereby
US4232953A (en) *	1979-06-27	1980-11-11	Alvarez Sabater Fernando	Gravity-feed rotary tray slide projector
IT1226045B (it) *	1981-07-29	1990-12-10	Simes	Derivati tetraidrochinolici
ATE23718T1 (de) *	1981-09-25	1986-12-15	Beecham Group Plc	Benzopyran-verbindungen mit pharmazeutischer wirkung.
FI79535C (fi) *	1982-05-06	1990-01-10	Erba Farmitalia	Foerfarande foer framstaellning av dihydrobensopyrans och dihydrobensotiopyrans substituerade iminoderivat.
US4500545A (en) *	1982-11-16	1985-02-19	Eli Lilly And Company	Hydroxyaminotetralincarboxamides
JPS59110690A (ja) *	1982-12-16	1984-06-26	Dai Ichi Seiyaku Co Ltd	ベンゾピラン誘導体
US4657925A (en) *	1984-08-13	1987-04-14	Nelson Research & Development Co.	Method and compositions for reducing the intraocular pressure of mammals
ATE64735T1 (de) *	1984-05-10	1991-07-15	Ciba Geigy Ag	Benzo-(pyrano und thiopyrano)-pyridine.
US4736031A (en) *	1985-06-10	1988-04-05	Takeda Chemical Industries, Ltd.	2-(piperazinylalkyl)-1-benzothiepin, 1-benzoxepin, and 1,5-benzodioxepin derivatives
DE3679378D1 (de) *	1985-09-03	1991-06-27	Ciba Geigy Ag	3-amino-dihydro-(1)-benzopyrane und benzothiopyrane.
SE8605504D0 (sv) *	1986-12-19	1986-12-19	Astra Laekemedel Ab	Novel chroman derivatives

1987
- 1987-02-27 US US07/020,054 patent/US4801605A/en not_active Expired - Fee Related
1988
- 1988-02-22 IL IL85494A patent/IL85494A0/xx unknown
- 1988-02-24 DE DE8888102716T patent/DE3868329D1/de not_active Expired - Lifetime
- 1988-02-24 ES ES198888102716T patent/ES2038707T3/es not_active Expired - Lifetime
- 1988-02-24 FI FI880866A patent/FI880866A7/fi not_active Application Discontinuation
- 1988-02-24 EP EP88102716A patent/EP0280269B1/de not_active Expired - Lifetime
- 1988-02-24 AT AT88102716T patent/ATE72563T1/de not_active IP Right Cessation
- 1988-02-25 PT PT86830A patent/PT86830B/pt not_active IP Right Cessation
- 1988-02-25 DD DD88313194A patent/DD273256A5/de unknown
- 1988-02-25 NZ NZ223647A patent/NZ223647A/en unknown
- 1988-02-25 YU YU00366/88A patent/YU36688A/xx unknown
- 1988-02-26 NO NO880843A patent/NO880843L/no unknown
- 1988-02-26 HU HU88928A patent/HU201920B/hu not_active IP Right Cessation
- 1988-02-26 ZA ZA881375A patent/ZA881375B/xx unknown
- 1988-02-26 DK DK100588A patent/DK100588A/da unknown
- 1988-02-26 PH PH36562A patent/PH23479A/en unknown
- 1988-02-26 KR KR1019880001965A patent/KR880009953A/ko not_active Withdrawn
- 1988-02-26 AU AU12347/88A patent/AU612625B2/en not_active Ceased
- 1988-02-27 JP JP63043340A patent/JPS63277671A/ja active Pending
1992
- 1992-02-13 GR GR910402100T patent/GR3003800T3/el unknown

Also Published As

Publication number	Publication date
AU1234788A (en)	1988-09-01
DK100588D0 (da)	1988-02-26
DD273256A5 (de)	1989-11-08
DE3868329D1 (de)	1992-03-26
ZA881375B (en)	1988-08-29
EP0280269B1 (de)	1992-02-12
IL85494A0 (en)	1988-07-31
FI880866A0 (fi)	1988-02-24
JPS63277671A (ja)	1988-11-15
HU201920B (en)	1991-01-28
EP0280269A1 (de)	1988-08-31
PT86830B (pt)	1992-05-29
YU36688A (en)	1990-04-30
ATE72563T1 (de)	1992-02-15
FI880866A7 (fi)	1988-08-28
KR880009953A (ko)	1988-10-06
ES2038707T3 (es)	1993-08-01
DK100588A (da)	1988-08-28
US4801605A (en)	1989-01-31
NO880843D0 (no)	1988-02-26
NZ223647A (en)	1991-06-25
PH23479A (en)	1989-08-07
GR3003800T3 (pt)	1993-03-16
NO880843L (no)	1988-08-29
AU612625B2 (en)	1991-07-18

Legal Events

Date

Code

Title

Description

1992-05-29

FG3A

Patent granted, date of granting

Effective date: 19911113

1993-10-29

MM3A

Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19930531

Publication	Publication Date	Title
PT86830A (pt)	1988-03-01	Process for preparing 3-amino-di-hydro-]1"-benzopyrans and benzothiopyrans and benzothiopyrans
ZA866685B (en)	1987-04-29	3-amino-dihydro-(1)-benzopyrans and benzothiopyrans
ES527295A0 (es)	1985-04-16	Metodo de preparar derivados de oxadiazolil-imidazo (1,4) benzodiazepina
EP0285287A3 (en)	1990-08-16	3-benzazepine compounds for use in treating gastrointestinal motility disorders
BE1003230A3 (fr)	1992-02-04	Nouveaux derives du benzotriazole, leur preparation et leur utilisation comme absorbants u.v.
ES2063381T3 (es)	1995-01-01	Antagonistas de los receptores muscarinicos.
DK583184D0 (da)	1984-12-06	Substituerede o-acyl-glycosylamider, fremgangsmaader til deres fremstilling samt deres anvendelse
HU913891D0 (en)	1992-02-28	Method for producing new phenyl-alkyl-amino-alkyl derivatives and medical preparatives containing said compounds
MA20857A1 (fr)	1987-10-01	Pyrrolo ( 1,2- a ) ( 4,1 ) benzoxazepines, procedes pour leur preparation.
PE123599A1 (es)	1999-12-20	Derivados de bifenilo
ES2055155T3 (es)	1994-08-16	Procedimiento para la obtencion de aciloxiacetidinonas opticamente activas.
DK294389A (da)	1989-12-16	Nye benzazepin derivater