DD283864A5 - Verfahren und behaeltnis zum gefriertrocknen unter sterilen bedingungen - Google Patents

Verfahren und behaeltnis zum gefriertrocknen unter sterilen bedingungen Download PDF

Info

Publication number: DD283864A5
Authority: DD; German Democratic Republic
Prior art keywords: membrane; container; freeze; drying; dried
Prior art date: 1988-05-26

Application number

DD89328870A

Other languages

German (de)

English (en)

Inventor

Thomas Bergmann

Herbert Brustmann

Original Assignee

��@��@��k��

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-05-26

Filing date

1989-05-24

Publication date

1990-10-24

1989-05-24 Application filed by ��@��@��k�� filed Critical ��@��@��k��

1990-10-24 Publication of DD283864A5 publication Critical patent/DD283864A5/de

Links

238000000034 method Methods 0.000 title claims abstract description 28
238000004108 freeze drying Methods 0.000 title claims abstract description 15
239000012528 membrane Substances 0.000 claims abstract description 33
239000000463 material Substances 0.000 claims abstract description 27
230000002209 hydrophobic effect Effects 0.000 claims abstract description 4
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 9
239000011148 porous material Substances 0.000 claims description 5
239000001913 cellulose Substances 0.000 claims description 4
229920002678 cellulose Polymers 0.000 claims description 4
-1 polytetrafluoroethylene Polymers 0.000 claims description 4
150000001875 compounds Chemical class 0.000 claims description 3
239000004743 Polypropylene Substances 0.000 claims description 2
229920002301 cellulose acetate Polymers 0.000 claims description 2
229920000642 polymer Polymers 0.000 claims description 2
229920001155 polypropylene Polymers 0.000 claims description 2
229920001343 polytetrafluoroethylene Polymers 0.000 claims description 2
239000004810 polytetrafluoroethylene Substances 0.000 claims description 2
239000003708 ampul Substances 0.000 claims 1
239000012620 biological material Substances 0.000 abstract 1
238000001035 drying Methods 0.000 description 18
239000000243 solution Substances 0.000 description 9
239000000126 substance Substances 0.000 description 5
244000052616 bacterial pathogen Species 0.000 description 4
229920001817 Agar Polymers 0.000 description 3
239000008272 agar Substances 0.000 description 3
230000000813 microbial effect Effects 0.000 description 3
244000005700 microbiome Species 0.000 description 3
235000015097 nutrients Nutrition 0.000 description 3
238000000859 sublimation Methods 0.000 description 3
230000008022 sublimation Effects 0.000 description 3
FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 2
230000001580 bacterial effect Effects 0.000 description 2
238000011109 contamination Methods 0.000 description 2
239000011888 foil Substances 0.000 description 2
239000002904 solvent Substances 0.000 description 2
239000008223 sterile water Substances 0.000 description 2
230000001954 sterilising effect Effects 0.000 description 2
238000004659 sterilization and disinfection Methods 0.000 description 2
238000012360 testing method Methods 0.000 description 2
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
229920000544 Gore-Tex Polymers 0.000 description 1
239000001888 Peptone Substances 0.000 description 1
108010080698 Peptones Proteins 0.000 description 1
XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 1
229910052782 aluminium Inorganic materials 0.000 description 1
239000006161 blood agar Substances 0.000 description 1
239000012876 carrier material Substances 0.000 description 1
238000005520 cutting process Methods 0.000 description 1
238000000354 decomposition reaction Methods 0.000 description 1
230000001419 dependent effect Effects 0.000 description 1
230000002349 favourable effect Effects 0.000 description 1
238000001914 filtration Methods 0.000 description 1
230000008014 freezing Effects 0.000 description 1
238000007710 freezing Methods 0.000 description 1
239000008103 glucose Substances 0.000 description 1
239000012535 impurity Substances 0.000 description 1
239000011261 inert gas Substances 0.000 description 1
208000015181 infectious disease Diseases 0.000 description 1
230000036512 infertility Effects 0.000 description 1
238000002347 injection Methods 0.000 description 1
239000007924 injection Substances 0.000 description 1
210000004072 lung Anatomy 0.000 description 1
238000004519 manufacturing process Methods 0.000 description 1
238000004643 material aging Methods 0.000 description 1
229940091925 mediplast Drugs 0.000 description 1
230000006911 nucleation Effects 0.000 description 1
238000010899 nucleation Methods 0.000 description 1
238000004806 packaging method and process Methods 0.000 description 1
235000019319 peptone Nutrition 0.000 description 1
230000035699 permeability Effects 0.000 description 1
239000000825 pharmaceutical preparation Substances 0.000 description 1
239000004033 plastic Substances 0.000 description 1
239000000843 powder Substances 0.000 description 1
238000007789 sealing Methods 0.000 description 1
239000011780 sodium chloride Substances 0.000 description 1
238000003860 storage Methods 0.000 description 1
239000000725 suspension Substances 0.000 description 1
238000003466 welding Methods 0.000 description 1

Classifications

- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F26—DRYING
- F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
- F26B5/00—Drying solid materials or objects by processes not involving the application of heat
- F26B5/04—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum
- F26B5/06—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum the process involving freezing

Landscapes

Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
Molecular Biology (AREA)
Mechanical Engineering (AREA)
General Engineering & Computer Science (AREA)
Health & Medical Sciences (AREA)
Medical Preparation Storing Or Oral Administration Devices (AREA)
Drying Of Solid Materials (AREA)
Freezing, Cooling And Drying Of Foods (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Separation Using Semi-Permeable Membranes (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

DD89328870A 1988-05-26 1989-05-24 Verfahren und behaeltnis zum gefriertrocknen unter sterilen bedingungen DD283864A5 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE3817906A DE3817906A1 (de)	1988-05-26	1988-05-26	Verfahren und behaeltnis zum gefriertrocknen unter sterilen bedingungen

Publications (1)

Publication Number	Publication Date
DD283864A5 true DD283864A5 (de)	1990-10-24

Family

ID=6355171

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DD89328870A DD283864A5 (de)	1988-05-26	1989-05-24	Verfahren und behaeltnis zum gefriertrocknen unter sterilen bedingungen

Country Status (13)

Country	Link
EP (1)	EP0343596B1 (fr)
JP (1)	JPH0229256A (fr)
AT (1)	ATE73226T1 (fr)
CA (1)	CA1337974C (fr)
DD (1)	DD283864A5 (fr)
DE (2)	DE3817906A1 (fr)
DK (1)	DK173643B1 (fr)
ES (1)	ES2030556T3 (fr)
FI (1)	FI91442C (fr)
GR (1)	GR3004584T3 (fr)
HU (1)	HU204126B (fr)
IE (1)	IE61012B1 (fr)
PL (1)	PL159938B1 (fr)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IL90188A0 (en) *	1988-05-18	1989-12-15	Cryopharm Corp	Process and medium for the lyophilization of erythrocytes
US5045446A (en) *	1988-08-26	1991-09-03	Cryopharm Corporation	Lyophilization of cells
US5257983A (en) *	1991-04-12	1993-11-02	Cryopharm Corporation	Blood bag for lyophilization
AU7356094A (en) *	1994-04-04	1995-10-23	W.L. Gore & Associates, Inc.	Improved method for minimizing contamination of freeze-dried products
DE69412291T2 (de) *	1994-08-19	1998-12-03	W.L. Gore & Associates, Inc., Newark, Del.	Ventilierte glasflasche zur gefriertrocknung und verfahren zur verminderung der kontamination von gefriergetrockneten produkten
FR2740108B1 (fr) *	1995-08-22	1998-03-27	Lab Francais Du Fractionnement	Emballage etanche pour sechage, notamment lyophilisation, et procede de sechage, notamment de lyophilisation, a l'aide d'un tel emballage
FR2738057B1 (fr) *	1995-08-22	1997-11-07	Lab Francais Du Fractionnement	Emballage etanche pour sechage, notamment lyophilisation, et procede de sechage, notamment de lyophilisation, a l'aide d'un tel emballage
WO1997011155A1 (fr)	1995-09-22	1997-03-27	Government Of The United States Of America, Represented By The Secretary Of The Department Of Health And Human Services	Recipient pour secher des echantillons biologiques, procede de fabrication et mode d'utilisation dudit recipient
US5596814A (en) *	1995-11-06	1997-01-28	W. L. Gore & Associates, Inc.	Vented vial stopper for processing freeze-dried products
AT1399U1 (de)	1995-11-29	1997-04-25	Immuno Ag	Verfahren und einrichtung zum lyophilisieren
DE19751031A1 (de) *	1997-11-19	1999-06-24	Ingo Dipl Ing Heschel	Verfahren zur Herstellung poröser Strukturen
US6312648B1 (en)	1998-01-12	2001-11-06	The United States Of America As Represented By The Department Of Health And Human Services	Applicator system
DE19815993C2 (de) *	1998-04-09	2003-03-06	Schott Glas	Behälter zur Gefriertrocknung und Aufbewahrung medizinischer Produkte
EP1958618A1 (fr)	2007-02-15	2008-08-20	Octapharma AG	Procédé destiné à la lyophilisation par reconstitution optimisée de biopolymères
JP2010124931A (ja) *	2008-11-26	2010-06-10	Kanae Co Ltd	凍結乾燥製剤の包装体の製造方法
EP2386399B8 (fr) *	2010-04-23	2015-08-05	MC Beteiligungs-GmbH	Procédé pour faire des trous dans un revêtement étanche et corps de base avec un tel revêtement
WO2015162273A1 (fr)	2014-04-25	2015-10-29	Merck Sharp & Dohme Bv	Procédé pour assécher de multiples corps individuels congelés et système permettant d'appliquer ce procédé
WO2019074886A1 (fr)	2017-10-09	2019-04-18	Terumo Bct Biotechnologies, Llc	Récipient de lyophilisation et son procédé d'utilisation
JP2019090596A (ja) *	2017-11-10	2019-06-13	エイブル株式会社	凍結乾燥生成物の製造方法、及び、凍結乾燥用袋、並びに、凍結乾燥装置
US11609042B2 (en)	2019-03-14	2023-03-21	Terumo Bct Biotechnologies, Llc	Multi-part lyophilization container and method of use
DE102023118662B3 (de) *	2023-07-13	2024-07-11	Jürgen Kögel	Gefriertrocknungsbehälter

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
BE620147A (fr) *	1961-07-17
BE622411A (fr) *	1961-11-28
GB1154320A (en) *	1965-09-24	1969-06-04	Unilever Ltd	Freeze Drying
FR2284842A1 (fr) *	1974-09-11	1976-04-09	Nestle Sa	Perfectionnement apporte la lyophilisation des produits solides, liquides ou pateux
JPS60168464A (ja) *	1983-11-18	1985-08-31	新技術事業団	血液保存方法及びその保存用容器
JPS6136942A (ja) *	1984-07-28	1986-02-21	Sony Corp	電子部品装置

1988
- 1988-05-26 DE DE3817906A patent/DE3817906A1/de not_active Withdrawn
1989
- 1989-05-11 IE IE154189A patent/IE61012B1/en not_active IP Right Cessation
- 1989-05-19 CA CA000600212A patent/CA1337974C/fr not_active Expired - Lifetime
- 1989-05-23 AT AT89109246T patent/ATE73226T1/de not_active IP Right Cessation
- 1989-05-23 ES ES198989109246T patent/ES2030556T3/es not_active Expired - Lifetime
- 1989-05-23 EP EP89109246A patent/EP0343596B1/fr not_active Expired - Lifetime
- 1989-05-23 DE DE8989109246T patent/DE58900902D1/de not_active Expired - Lifetime
- 1989-05-24 DD DD89328870A patent/DD283864A5/de not_active IP Right Cessation
- 1989-05-24 DK DK198902525A patent/DK173643B1/da not_active IP Right Cessation
- 1989-05-24 PL PL1989279609A patent/PL159938B1/pl unknown
- 1989-05-25 FI FI892563A patent/FI91442C/fi not_active IP Right Cessation
- 1989-05-25 HU HU892683A patent/HU204126B/hu unknown
- 1989-05-26 JP JP1131693A patent/JPH0229256A/ja active Granted
1992
- 1992-05-13 GR GR920400224T patent/GR3004584T3/el unknown

Also Published As

Publication number	Publication date
EP0343596B1 (fr)	1992-03-04
FI892563A0 (fi)	1989-05-25
PL159938B1 (pl)	1993-01-29
EP0343596A3 (en)	1990-02-28
PL279609A1 (en)	1990-01-22
JPH0450830B2 (fr)	1992-08-17
IE891541L (en)	1989-11-26
ES2030556T3 (es)	1992-11-01
FI91442C (fi)	1994-06-27
EP0343596A2 (fr)	1989-11-29
CA1337974C (fr)	1996-01-23
DE3817906A1 (de)	1989-11-30
FI892563L (fi)	1989-11-27
JPH0229256A (ja)	1990-01-31
HU204126B (en)	1991-11-28
GR3004584T3 (fr)	1993-04-28
DK252589D0 (da)	1989-05-24
DK252589A (da)	1989-11-27
ATE73226T1 (de)	1992-03-15
DE58900902D1 (de)	1992-04-09
DK173643B1 (da)	2001-05-14
HUT52617A (en)	1990-07-28
FI91442B (fi)	1994-03-15
IE61012B1 (en)	1994-09-07

Legal Events

Date	Code	Title	Description
1996-06-20	ENJ	Ceased due to non-payment of renewal fee

Publication	Publication Date	Title
EP0343596B1 (fr)	1992-03-04	Récipient pour lyophilisation sous conditions stériles
DE69933309T2 (de)	2007-04-05	Verfahren zur zucht von mikroorganismen in vorgefüllten flexiblen behältern
DE2164779C3 (de)	1981-04-30	Verfahren zur Herstellung sterilisierter Gegenstände
EP3461750B1 (fr)	2024-03-06	Récipient destiné à la réception du matériau d'emballage
AT16945U1 (de)	2020-12-15	Durch Gammastrahlung sterilisierbarer Taschenaufbau
DE8231028U1 (de)	1983-02-03	Verpackung zur Lagerung eines medizinischen Behaelters
WO2015062744A1 (fr)	2015-05-07	Ensemble soupape casse-vide pour récipient de stérilisation sous vide
DE2742588A1 (de)	1978-03-30	Verfahren zur sterilisation eines dialysators mit semipermeabler membran
EP3285815B1 (fr)	2025-02-26	Procédé de stérilisation de matériel de chromatographie et matériel de chromatographie stérilisé
DE2027604B2 (de)	1974-03-28	Vorrichtung zur Anzeige des Grades der biologischen Wirksamkeit eines Desinfektionsmittels oder -Verfahrens
DE102007004114B3 (de)	2008-02-14	Geschützte Filtereinheiten zur Sicherheitsfiltration und Verfahren zu ihrer Herstellung
DE1792157C3 (de)	1978-12-07	Verfahren zum Sterilisieren von festen Oberflächen
EP1485135B1 (fr)	2005-08-24	Procede pour controler une unite de conditionnement de sterilisation quant a son efficacite contre la contamination
DE2914529A1 (de)	1979-10-18	Verfahren zum pilzresistent-ausruesten von kollagenfilmen
EP1624903B1 (fr)	2007-03-14	Unite de verification et procede permettant de verifier l'efficacite d'une unite d'emballage de sterilisation contre la recontamination, et emballage de type conteneur servant a la mise en oeuvre dudit procede
CH653894A5 (de)	1986-01-31	Kuenstliches organ und verfahren zu dessen sterilisation.
EP3721975B1 (fr)	2022-09-21	Procédé de fabrication d'un produit filtrant sans particules, conditionné stérilisé
DE3136758A1 (de)	1983-03-31	Verpackungseinheit und verfahren zu dessen herstellung
DE3212935A1 (de)	1983-09-15	Verfahren zur sterilisation von einmal-injektionsspritzen
AT206585B (fr)	1959-12-10
DE1013837B (de)	1957-08-14	Verfahren und Mittel zur Durchfuehrung bakteriologischer Arbeiten
DE2353273C3 (de)	1977-02-10	Quaderförmiger Behälter aus durchsichtigem Material mit hermetisch abzuschließendem Deckel zur Präparation und Aufbewahrung von Kulturen von pilzartigen Parasiten oder dgl
DD229305B1 (de)	1987-09-02	Verfahren zur herstellung kaltsterilisierter gegenstaende
DE2353273B2 (de)	1976-06-24	Quaderfoermiger behaelter aus durchsichtigem material mit hermetisch abzuschliessendem deckel zur praeparation und aufbewahrung von kulturen von pilzartigen parasiten oder dgl.
DE8213134U1 (de)	1985-05-15	Bioindikator