DD284899A5 - Verfahren zur herstellung eines plasmodium-impfstoffes - Google Patents

Verfahren zur herstellung eines plasmodium-impfstoffes Download PDF

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Publication number: DD284899A5
Authority: DD; German Democratic Republic
Prior art keywords: protein; dna; fragment; hbsag; plasmid
Prior art date: 1987-01-30

Application number

DD88334294A

Other languages

German (de)

English (en)

Inventor

Teresa Cabezon

Wilde Michel De

Nigel Harford

Original Assignee

��@��`��k��

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-01-30

Filing date

1988-01-29

Publication date

1990-11-28

1988-01-29 Application filed by ��@��`��k�� filed Critical ��@��`��k��

1990-11-28 Publication of DD284899A5 publication Critical patent/DD284899A5/de

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Classifications

- C—CHEMISTRY; METALLURGY
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- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
- C07K14/445—Plasmodium
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
- C12N15/78—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Pseudomonas
- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/735—Fusion polypeptide containing domain for protein-protein interaction containing a domain for self-assembly, e.g. a viral coat protein (includes phage display)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
- C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
- C—CHEMISTRY; METALLURGY
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- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16211—Human Immunodeficiency Virus, HIV concerning HIV gagpol
- C12N2740/16222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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Biochemistry (AREA)
Plant Pathology (AREA)
Physics & Mathematics (AREA)
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Proteomics, Peptides & Aminoacids (AREA)
Medicinal Chemistry (AREA)
Gastroenterology & Hepatology (AREA)
Virology (AREA)
Tropical Medicine & Parasitology (AREA)
Toxicology (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
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DD88334294A 1987-01-30 1988-01-29 Verfahren zur herstellung eines plasmodium-impfstoffes DD284899A5 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US932587A	1987-01-30	1987-01-30

Publications (1)

Publication Number	Publication Date
DD284899A5 true DD284899A5 (de)	1990-11-28

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ID=21736956

Family Applications (3)

Application Number	Title	Priority Date	Filing Date
DD88334294A DD284899A5 (de)	1987-01-30	1988-01-29	Verfahren zur herstellung eines plasmodium-impfstoffes
DD88334296A DD285612A5 (de)	1987-01-30	1988-01-29	Verfahren zur herstellung eines hiv-impfstoffes
DD88334295A DD285994A5 (de)	1987-01-30	1988-01-29	Verfahren zur herstellung eines hbv-impfstoffes

Family Applications After (2)

Application Number	Title	Priority Date	Filing Date
DD88334296A DD285612A5 (de)	1987-01-30	1988-01-29	Verfahren zur herstellung eines hiv-impfstoffes
DD88334295A DD285994A5 (de)	1987-01-30	1988-01-29	Verfahren zur herstellung eines hbv-impfstoffes

Country Status (20)

Country	Link
EP (1)	EP0278940A3 (fr)
JP (1)	JPS6463382A (fr)
KR (1)	KR880009130A (fr)
CN (1)	CN1031395A (fr)
AP (1)	AP56A (fr)
AU (1)	AU1093088A (fr)
DD (3)	DD284899A5 (fr)
DK (1)	DK43188A (fr)
FI (1)	FI880428L (fr)
HU (1)	HUT50876A (fr)
IL (1)	IL85216A0 (fr)
MA (1)	MA21169A1 (fr)
NO (1)	NO880395L (fr)
NZ (1)	NZ223297A (fr)
OA (1)	OA08801A (fr)
PT (1)	PT86640B (fr)
SU (1)	SU1746887A3 (fr)
TN (1)	TNSN88004A1 (fr)
YU (1)	YU17488A (fr)
ZA (1)	ZA88488B (fr)

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FR2635532B1 (fr) *	1988-07-29	1992-05-22	Pasteur Institut	Particules hbsag recombinantes hybrides : caracteristiques morphologiques de l'antigene hbsag contenant 1 sequence immunogene induisant des anticorps neutralisants diriges contre hiv ou susceptible d'etre reconnue par de tels anticorps; sequences nucleotidiques codant pour de telles particules; vaccins les contenant
CA2025481A1 (fr) *	1989-09-19	1991-03-20	Peter J. Kniskern	Vaccin contre le sida et l'hepatite b
US5130248A (en) *	1989-09-19	1992-07-14	Merck & Co., Inc.	Expression of fusion protein of HIV envelope and HBsAg
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EP0491077A1 (fr) *	1990-12-19	1992-06-24	Medeva Holdings B.V.	Composition utilisée comme agent thérapeutique contre des maladies hépatiques chroniques
AU2927892A (en) *	1991-11-16	1993-06-15	Smithkline Beecham Biologicals (Sa)	Hybrid protein between cs from plasmodium and hbsag
EP0618924B1 (fr) *	1991-12-23	2001-02-14	Bayer Corporation	Sondes d'amplification de vhb utlisees dans des methodes d'hybridation en sandwich a phase en solution
US6297048B1 (en)	1992-02-04	2001-10-02	Chiron Corporation	Hepatitis therapeutics
US5928902A (en) *	1992-02-27	1999-07-27	Smithkline Beecham Biologicals (S.A.)	Hybrid protein between CS from plasmodium and HBsAg
US6169171B1 (en)	1992-02-27	2001-01-02	Smithkline Beecham Biologicals (S.A.)	Hybrid protein between CS from plasmodium and HBSAG
US6709828B1 (en)	1992-03-06	2004-03-23	N.V. Innogenetics S.A.	Process for the determination of peptides corresponding to immunologically important epitopes and their use in a process for determination of antibodies or biotinylated peptides corresponding to immunologically important epitopes, a process for preparing them and compositions containing them
US6667387B1 (en)	1996-09-30	2003-12-23	N.V. Innogenetics S.A.	HCV core peptides
SG77551A1 (en) *	1992-03-06	2005-04-28	Innogenetics Nv	Process for the determination of peptides corresponding to immunologically important epitopes and their use in a process for determination of antibodies or biotinylated peptides corresponding to immunologically important epitopes, a process for preparing
EP0565794A1 (fr) *	1992-04-14	1993-10-20	British Biotech Pharmaceuticals Limited	Induction des réponses CTL
SG48365A1 (en)	1992-05-23	1998-04-17	Smithkline Beecham Biolog	Combined vaccines comprising hepatitis b surface antigen and other antigens
CN1063343C (zh) *	1993-04-27	2001-03-21	中国科学院上海生物化学研究所	氨端带前表面抗原决定簇的乙型肝炎表面抗原蛋白
US6235888B1 (en)	1994-10-05	2001-05-22	The General Hospital Corporation	Hepatitis C virus vaccine
RU2189254C2 (ru) *	1995-06-06	2002-09-20	Америкэн Хоум Продактс Корпорэйшн	Вакцины против вирусов гепатита
AU2800797A (en)	1996-04-05	1997-10-29	Chiron Corporation	Recombinant alphavirus-based vectors with reduced inhibition of cellular macromolecular synthesis
EP2298900A1 (fr)	1996-09-17	2011-03-23	Novartis Vaccines and Diagnostics, Inc.	Compositions et procédés de traitement de maladies intracellulaires
GB9623233D0 (en)	1996-11-07	1997-01-08	Smithkline Beecham Biolog	Vaccine composition
KR100629028B1 (ko)	1998-10-16	2006-09-26	글락소스미스클라인 바이오로지칼즈 에스.에이.	애쥬번트 시스템 및 백신
UA79735C2 (uk) *	2000-08-10	2007-07-25	Глаксосмітклайн Байолоджікалз С.А.	Очищення антигенів вірусу гепатиту b (hbv) для використання у вакцинах
CN100381171C (zh) *	2004-12-30	2008-04-16	成都生物制品研究所	含前s1、前s2和s抗原决定簇的乙肝表面抗原复合颗粒
CN102675430B (zh) *	2005-08-12	2014-08-27	上海贺普药业股份有限公司	乙型肝炎病毒表面l蛋白相关肽
EP2441469A1 (fr)	2006-03-14	2012-04-18	Oregon Health and Science University	Méthode pour produire une reponse contre la tuberculose
JP5814507B2 (ja)	2006-09-07	2015-11-17	グラクソスミスクラインバイオロジカルズソシエテアノニム	ワクチン
KR100836745B1 (ko) *	2007-01-31	2008-06-10	(주)두비엘	Ｈｂｖ 백신 및 그의 제조 방법
WO2008106551A2 (fr)	2007-02-28	2008-09-04	The Govt. Of The U.S.A. As Represented By The Secretary Of The Dept. Of Health & Human Serv.	Polypeptides brachyury et procédés d'utilisation.
JP2010525035A (ja)	2007-05-02	2010-07-22	グラクソスミスクラインバイオロジカルズソシエテアノニム	ワクチン
WO2009143524A2 (fr)	2008-05-23	2009-11-26	The Regents Of The University Of Michigan	Vaccins à nanoémulsion
WO2010099472A2 (fr)	2009-02-27	2010-09-02	The U.S.A. Of America, As Represented By The Secretary, Department Of Health And Human Services	Polypeptides spanx-b et leur utilisation
GB201105981D0 (en)	2011-04-08	2011-05-18	Glaxosmithkline Biolog Sa	Novel process
WO2014043518A1 (fr)	2012-09-14	2014-03-20	The United States Of America, As Represented By The Secretary, Department Of Health And Human Services	Protéine brachyury, vecteurs non levure, non poxvirus, codant pour la protéine brachyury, et leur utilisation
EP4137150A1 (fr)	2015-08-03	2023-02-22	The United States of America, as represented by the Secretary, Department of Health and Human Services	Mutants de délétion de la protéine brachyury, vecteurs sans levure codant pour les mutants de délétion de la protéine brachyury, et leur utilisation
CN119780431A (zh) *	2025-03-11	2025-04-08	泰州蕾灵百奥生物科技有限公司	一种用于检测猪流行性腹泻的试剂盒及其制备方法

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IL69202A (en) *	1982-09-08	1991-08-16	Smith Kline Rit	Surface antigen polypeptides of hbv virus produced in yeast and the preparation thereof
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EP0171908A3 (fr) *	1984-07-11	1987-07-15	Takeda Chemical Industries, Ltd.	Antigène de surface du virus de l'hépatite B et production
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EP0180012A1 (fr) *	1984-10-27	1986-05-07	Wolfram H. Prof. Dr. Gerlich	Séquence de polypeptide immunogène du virus de l'hépatite B
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US4683294A (en) *	1985-04-03	1987-07-28	Smith Kline Rit, S.A.	Process for the extraction and purification of proteins from culture media producing them
DE3689899T2 (de) *	1985-04-08	1994-09-15	Amgen	Verfahren und hybridpromotor zur steuerung der exogenen gentranskription.
FR2581394B1 (fr) *	1985-05-02	1988-08-05	Grp Genie Genetique	Particules ayant les proprietes immunogenes de l'antigene hbs et portant un site antigenique etranger aux epitopes portes par l'antigene hbs, vecteurs et cellules animales pour la production de telles particules et compositions contenant de telles particules pour la production de vaccins mixtes
US4816564A (en) *	1986-01-31	1989-03-28	Merck & Co., Inc.	Method for producing hepatitis B virus proteins in yeast
CA1310602C (fr) *	1986-06-03	1992-11-24	Hajime Horii	Promoteur de la levure et procede pour la preparation de proteines heterologues

1988
- 1988-01-25 AP APAP/P/1988/000078A patent/AP56A/en active
- 1988-01-25 ZA ZA88488A patent/ZA88488B/xx unknown
- 1988-01-25 EP EP88870008A patent/EP0278940A3/fr not_active Withdrawn
- 1988-01-26 NZ NZ223297A patent/NZ223297A/en unknown
- 1988-01-26 IL IL85216A patent/IL85216A0/xx unknown
- 1988-01-26 SU SU884355055A patent/SU1746887A3/ru active
- 1988-01-27 OA OA59269A patent/OA08801A/fr unknown
- 1988-01-27 PT PT86640A patent/PT86640B/pt not_active IP Right Cessation
- 1988-01-28 DK DK043188A patent/DK43188A/da not_active Application Discontinuation
- 1988-01-28 AU AU10930/88A patent/AU1093088A/en not_active Abandoned
- 1988-01-29 YU YU00174/88A patent/YU17488A/xx unknown
- 1988-01-29 HU HU88409A patent/HUT50876A/hu unknown
- 1988-01-29 JP JP63021137A patent/JPS6463382A/ja active Pending
- 1988-01-29 DD DD88334294A patent/DD284899A5/de not_active IP Right Cessation
- 1988-01-29 FI FI880428A patent/FI880428L/fi not_active IP Right Cessation
- 1988-01-29 DD DD88334296A patent/DD285612A5/de unknown
- 1988-01-29 MA MA21406A patent/MA21169A1/fr unknown
- 1988-01-29 DD DD88334295A patent/DD285994A5/de not_active IP Right Cessation
- 1988-01-29 NO NO880395A patent/NO880395L/no unknown
- 1988-01-30 CN CN88100483A patent/CN1031395A/zh active Pending
- 1988-01-30 KR KR1019880000825A patent/KR880009130A/ko not_active Withdrawn
- 1988-02-03 TN TNTNSN88004A patent/TNSN88004A1/fr unknown

Also Published As

Publication number	Publication date
KR880009130A (ko)	1988-09-14
EP0278940A2 (fr)	1988-08-17
NO880395L (no)	1988-08-01
CN1031395A (zh)	1989-03-01
HUT50876A (en)	1990-03-28
AU1093088A (en)	1988-08-04
DD285612A5 (de)	1990-12-19
FI880428A7 (fi)	1988-07-31
JPS6463382A (en)	1989-03-09
OA08801A (fr)	1989-03-31
DK43188A (da)	1988-07-31
MA21169A1 (fr)	1988-10-01
PT86640A (pt)	1988-02-01
YU17488A (en)	1991-02-28
TNSN88004A1 (fr)	1990-07-10
PT86640B (pt)	1992-01-31
SU1746887A3 (ru)	1992-07-07
FI880428A0 (fi)	1988-01-29
DK43188D0 (da)	1988-01-28
NO880395D0 (no)	1988-01-29
FI880428L (fi)	1988-09-13
AP56A (en)	1989-09-26
EP0278940A3 (fr)	1988-12-07
DD285994A5 (de)	1991-01-10
AP8800078A0 (en)	1987-11-01
ZA88488B (en)	1988-10-26
NZ223297A (en)	1991-06-25
IL85216A0 (en)	1988-07-31

Legal Events

Date	Code	Title	Description
1995-07-20	ENJ	Ceased due to non-payment of renewal fee

Publication	Publication Date	Title
DD284899A5 (de)	1990-11-28	Verfahren zur herstellung eines plasmodium-impfstoffes
DE3789399T2 (de)	1994-10-06	Herstellung von Vakkzinen gegen Hepatitis B-Virus.
DE69031556T2 (de)	1998-05-14	Antigene sowie Verfahren zu deren Herstellung
DE69228698T2 (de)	1999-09-16	HYBRIDES PROTEIN ZWISCHEN CS AUS PLASMODIUM UND HBsAG
DE3788902T3 (de)	2004-11-25	Hepatitis-Delta-Diagnostika und Impfstoffe, ihre Herstellung und Verwendung.
DE3280468T2 (de)	1995-12-07	Synthese von menschlichen Virusantigenen durch Hefe.
DE60117978T2 (de)	2006-11-02	Modifizierung des hepatitis b kernantigens
US4618578A (en)	1986-10-21	Expression of glycoprotein D of herpes simplex virus
US6306625B1 (en)	2001-10-23	Method for obtaining expression of mixed polypeptide particles in yeast
DE3856496T2 (de)	2002-06-27	Hepatitis-B-Oberflächenantigen enthaltendes Peptid
DE3587991T2 (de)	1995-07-20	Rekombinanter herpes simplex gb-gd impfstoff.
DE69131200T2 (de)	1999-12-09	Herpes simplex virus vp16 impfstoffe
DE3382704T2 (de)	1994-02-10	Rekombinante DNS-Moleküle die Hepatitis-B-Oberflächenantigen kodieren, deren Herstellung und abgeleitete Vakzine.
DE69018926T2 (de)	1995-08-24	Vakzine gegen Bordetella.
DE3875043T2 (de)	1993-02-25	Immunogenes produkt, erhalten durch expression in einer rekombinanten hefe, und verfahren zu seiner reinigung.
DE69013471T2 (de)	1995-03-30	Methode zur Stabilisierung von rekombinanten Hepatitis-B-Virus-Oberflächenproteinen aus Hefe.
DE3685837T2 (de)	1992-12-17	Hepatitis-a-virus-impfstoff.
DE69130724T2 (de)	1999-06-17	Verfahren zur Gewinnung von rekombinantem Hepatitis B Virus (HEP B) Oberflächeantigen
DE69214980T2 (de)	1997-05-15	Verfahren zur Reinigung von rekombinantem Hepatitis B-Virus-Oberflächenproteinen aus rekombinanten Zellen
DE3787131T2 (de)	1994-02-03	Varicella-Zoster-Virus als lebende rekombinante Vakzine.
AT409863B (de)	2002-12-27	Hoch effiziente expression eines polypeptids, das eine modifizierte pres1-region des grossen hepatitis b-virus-antigens enthält
DD274052A5 (de)	1989-12-06	Verfahren zur Herstellung von Rekombinanten Hbv-, Hiv- oder Plasmodium-Oberflächenproteinen bzw. Hybridpartikeln
EP0503252B1 (fr)	2001-04-04	Protéines recombinantes ayant l'activité immunologique de l'antigène e du virus de l'hépatite B (HBeAg), procédé de leur production ainsi que leur utilisation dans des assays immunologiques et comme vaccins
DE3588244T2 (de)	2003-09-11	Rekombinanter Herpes Simplex gB-gD-Impfstoff
AT388934B (de)	1989-09-25	Rekombinationskonjugatprotein und neue vakzinen