DD302011A9 - Glasiges oder glasig-kristallines Material mit schneller Loeslichkeit und Verfahren zu seiner Herstellung - Google Patents

Glasiges oder glasig-kristallines Material mit schneller Loeslichkeit und Verfahren zu seiner Herstellung Download PDF

Info

Publication number: DD302011A9
Authority: DD; German Democratic Republic
Prior art keywords: phase; material according; crystalline; mgo; cao
Prior art date: 1989-11-13

Application number

DD33452489A

Other languages

German (de)

English (en)

Inventor

Georg Dr Sc Techn Berger

Renate Dipl-Chem Sauer

Gabriele Dipl-Chem Steinborn

Wolfram Dr Med Knoefler

Hans-Ludwig Dr Med Graf

Volker Doz Dr Dr Sc Med Thieme

Horst Dipl-Ing Dressel

Olaf Dipl-Chem Guenther

Original Assignee

Biovision Gmbh Entwicklung

Univ Leipzig

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-11-13

Filing date

1989-11-13

Publication date

1994-11-03

1989-11-13 Application filed by Biovision Gmbh Entwicklung, Univ Leipzig filed Critical Biovision Gmbh Entwicklung

1989-11-13 Priority to DD33452489A priority Critical patent/DD302011A9/de

1990-11-12 Priority to AT90916242T priority patent/ATE112540T1/de

1990-11-12 Priority to ES90916242T priority patent/ES2064769T3/es

1990-11-12 Priority to PCT/DE1990/000875 priority patent/WO1991007357A1/de

1990-11-12 Priority to DE59007405T priority patent/DE59007405D1/de

1990-11-12 Priority to EP90916242A priority patent/EP0541546B1/de

1994-11-03 Publication of DD302011A9 publication Critical patent/DD302011A9/de

Links

238000000034 method Methods 0.000 title claims description 24
239000002178 crystalline material Substances 0.000 title claims description 7
238000002360 preparation method Methods 0.000 title claims description 6
239000000463 material Substances 0.000 claims abstract description 99
239000000203 mixture Substances 0.000 claims abstract description 46
239000013078 crystal Substances 0.000 claims abstract description 32
238000001816 cooling Methods 0.000 claims abstract description 16
210000000988 bone and bone Anatomy 0.000 claims abstract description 15
QXJJQWWVWRCVQT-UHFFFAOYSA-K calcium;sodium;phosphate Chemical compound [Na+].[Ca+2].[O-]P([O-])([O-])=O QXJJQWWVWRCVQT-UHFFFAOYSA-K 0.000 claims abstract description 12
229910001467 sodium calcium phosphate Inorganic materials 0.000 claims abstract description 12
239000007943 implant Substances 0.000 claims abstract description 8
230000000975 bioactive effect Effects 0.000 claims abstract description 6
OTYBMLCTZGSZBG-UHFFFAOYSA-L potassium sulfate Chemical compound [K+].[K+].[O-]S([O-])(=O)=O OTYBMLCTZGSZBG-UHFFFAOYSA-L 0.000 claims abstract description 5
229910052939 potassium sulfate Inorganic materials 0.000 claims abstract description 5
239000002241 glass-ceramic Substances 0.000 claims abstract description 4
229910052708 sodium Inorganic materials 0.000 claims description 20
229910004298 SiO 2 Inorganic materials 0.000 claims description 19
239000000126 substance Substances 0.000 claims description 17
239000000155 melt Substances 0.000 claims description 13
239000008187 granular material Substances 0.000 claims description 10
239000000470 constituent Substances 0.000 claims description 9
QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 claims description 8
239000000316 bone substitute Substances 0.000 claims description 7
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 5
235000011151 potassium sulphates Nutrition 0.000 claims description 4
230000015572 biosynthetic process Effects 0.000 claims description 3
239000000919 ceramic Substances 0.000 claims description 3
229910018072 Al 2 O 3 Inorganic materials 0.000 claims description 2
229910045601 alloy Inorganic materials 0.000 claims description 2
239000000956 alloy Substances 0.000 claims description 2
239000012153 distilled water Substances 0.000 claims description 2
229910052588 hydroxylapatite Inorganic materials 0.000 claims description 2
229910052751 metal Inorganic materials 0.000 claims description 2
239000002184 metal Substances 0.000 claims description 2
150000002739 metals Chemical class 0.000 claims description 2
XYJRXVWERLGGKC-UHFFFAOYSA-D pentacalcium;hydroxide;triphosphate Chemical compound [OH-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O XYJRXVWERLGGKC-UHFFFAOYSA-D 0.000 claims description 2
210000001519 tissue Anatomy 0.000 claims description 2
238000000137 annealing Methods 0.000 claims 1
239000011248 coating agent Substances 0.000 claims 1
238000000576 coating method Methods 0.000 claims 1
238000010304 firing Methods 0.000 claims 1
238000000465 moulding Methods 0.000 claims 1
239000003337 fertilizer Substances 0.000 abstract description 16
210000002808 connective tissue Anatomy 0.000 abstract description 10
VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 abstract 2
KKCBUQHMOMHUOY-UHFFFAOYSA-N Na2O Inorganic materials [O-2].[Na+].[Na+] KKCBUQHMOMHUOY-UHFFFAOYSA-N 0.000 abstract 1
239000007832 Na2SO4 Substances 0.000 abstract 1
PMZURENOXWZQFD-UHFFFAOYSA-L Sodium Sulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=O PMZURENOXWZQFD-UHFFFAOYSA-L 0.000 abstract 1
229910052681 coesite Inorganic materials 0.000 abstract 1
238000002485 combustion reaction Methods 0.000 abstract 1
229910052906 cristobalite Inorganic materials 0.000 abstract 1
239000000377 silicon dioxide Substances 0.000 abstract 1
235000012239 silicon dioxide Nutrition 0.000 abstract 1
229910052938 sodium sulfate Inorganic materials 0.000 abstract 1
235000011152 sodium sulphate Nutrition 0.000 abstract 1
229910052682 stishovite Inorganic materials 0.000 abstract 1
229910052905 tridymite Inorganic materials 0.000 abstract 1
239000011734 sodium Substances 0.000 description 32
239000011521 glass Substances 0.000 description 10
241001465754 Metazoa Species 0.000 description 7
239000011575 calcium Substances 0.000 description 7
238000004519 manufacturing process Methods 0.000 description 6
OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 5
DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 5
229910019142 PO4 Inorganic materials 0.000 description 5
ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 description 5
NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 5
239000010452 phosphate Substances 0.000 description 5
239000011591 potassium Substances 0.000 description 5
238000007920 subcutaneous administration Methods 0.000 description 5
OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 description 4
NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 description 4
238000007792 addition Methods 0.000 description 4
229910052791 calcium Inorganic materials 0.000 description 4
239000001506 calcium phosphate Substances 0.000 description 4
230000000694 effects Effects 0.000 description 4
238000002513 implantation Methods 0.000 description 4
238000002844 melting Methods 0.000 description 4
230000008018 melting Effects 0.000 description 4
125000005341 metaphosphate group Chemical group 0.000 description 4
239000011574 phosphorus Substances 0.000 description 4
229910052698 phosphorus Inorganic materials 0.000 description 4
229910052700 potassium Inorganic materials 0.000 description 4
229910052717 sulfur Inorganic materials 0.000 description 4
239000011593 sulfur Substances 0.000 description 4
RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 description 3
FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 description 3
QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 description 3
239000010941 cobalt Substances 0.000 description 3
229910017052 cobalt Inorganic materials 0.000 description 3
GUTLYIVDDKVIGB-UHFFFAOYSA-N cobalt atom Chemical compound [Co] GUTLYIVDDKVIGB-UHFFFAOYSA-N 0.000 description 3
229910052802 copper Inorganic materials 0.000 description 3
239000010949 copper Substances 0.000 description 3
230000006698 induction Effects 0.000 description 3
239000011777 magnesium Substances 0.000 description 3
229910052749 magnesium Inorganic materials 0.000 description 3
239000000047 product Substances 0.000 description 3
239000000523 sample Substances 0.000 description 3
239000002689 soil Substances 0.000 description 3
238000006467 substitution reaction Methods 0.000 description 3
238000012360 testing method Methods 0.000 description 3
239000011573 trace mineral Substances 0.000 description 3
235000013619 trace mineral Nutrition 0.000 description 3
229910000391 tricalcium phosphate Inorganic materials 0.000 description 3
235000019731 tricalcium phosphate Nutrition 0.000 description 3
229940078499 tricalcium phosphate Drugs 0.000 description 3
IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 2
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 2
JLVVSXFLKOJNIY-UHFFFAOYSA-N Magnesium ion Chemical compound [Mg+2] JLVVSXFLKOJNIY-UHFFFAOYSA-N 0.000 description 2
NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 description 2
BUGBHKTXTAQXES-UHFFFAOYSA-N Selenium Chemical compound [Se] BUGBHKTXTAQXES-UHFFFAOYSA-N 0.000 description 2
239000003674 animal food additive Substances 0.000 description 2
229910001424 calcium ion Inorganic materials 0.000 description 2
239000000969 carrier Substances 0.000 description 2
239000012876 carrier material Substances 0.000 description 2
238000002425 crystallisation Methods 0.000 description 2
230000008025 crystallization Effects 0.000 description 2
230000007547 defect Effects 0.000 description 2
230000003111 delayed effect Effects 0.000 description 2
238000002474 experimental method Methods 0.000 description 2
230000002349 favourable effect Effects 0.000 description 2
238000011049 filling Methods 0.000 description 2
230000035876 healing Effects 0.000 description 2
238000002386 leaching Methods 0.000 description 2
229910001425 magnesium ion Inorganic materials 0.000 description 2
230000011164 ossification Effects 0.000 description 2
229910052760 oxygen Inorganic materials 0.000 description 2
239000002245 particle Substances 0.000 description 2
229910001414 potassium ion Inorganic materials 0.000 description 2
150000003839 salts Chemical class 0.000 description 2
229910052711 selenium Inorganic materials 0.000 description 2
239000011669 selenium Substances 0.000 description 2
229910001415 sodium ion Inorganic materials 0.000 description 2
239000002195 soluble material Substances 0.000 description 2
230000002269 spontaneous effect Effects 0.000 description 2
238000003860 storage Methods 0.000 description 2
150000003467 sulfuric acid derivatives Chemical class 0.000 description 2
229910021653 sulphate ion Inorganic materials 0.000 description 2
239000000725 suspension Substances 0.000 description 2
238000005496 tempering Methods 0.000 description 2
230000009772 tissue formation Effects 0.000 description 2
ZOXJGFHDIHLPTG-UHFFFAOYSA-N Boron Chemical compound [B] ZOXJGFHDIHLPTG-UHFFFAOYSA-N 0.000 description 1
BHPQYMZQTOCNFJ-UHFFFAOYSA-N Calcium cation Chemical compound [Ca+2] BHPQYMZQTOCNFJ-UHFFFAOYSA-N 0.000 description 1
ZOKXTWBITQBERF-UHFFFAOYSA-N Molybdenum Chemical compound [Mo] ZOKXTWBITQBERF-UHFFFAOYSA-N 0.000 description 1
241000283973 Oryctolagus cuniculus Species 0.000 description 1
241000700159 Rattus Species 0.000 description 1
XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 description 1
241000282887 Suidae Species 0.000 description 1
235000002096 Vicia faba var. equina Nutrition 0.000 description 1
238000002441 X-ray diffraction Methods 0.000 description 1
HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 description 1
229910000147 aluminium phosphate Inorganic materials 0.000 description 1
238000004458 analytical method Methods 0.000 description 1
229910052586 apatite Inorganic materials 0.000 description 1
238000003556 assay Methods 0.000 description 1
230000009286 beneficial effect Effects 0.000 description 1
239000000560 biocompatible material Substances 0.000 description 1
210000000746 body region Anatomy 0.000 description 1
230000037237 body shape Effects 0.000 description 1
229910052796 boron Inorganic materials 0.000 description 1
229910000389 calcium phosphate Inorganic materials 0.000 description 1
239000004068 calcium phosphate ceramic Substances 0.000 description 1
235000011010 calcium phosphates Nutrition 0.000 description 1
238000001311 chemical methods and process Methods 0.000 description 1
239000007795 chemical reaction product Substances 0.000 description 1
239000012141 concentrate Substances 0.000 description 1
238000007796 conventional method Methods 0.000 description 1
230000003247 decreasing effect Effects 0.000 description 1
230000007812 deficiency Effects 0.000 description 1
238000004090 dissolution Methods 0.000 description 1
239000000428 dust Substances 0.000 description 1
235000005489 dwarf bean Nutrition 0.000 description 1
244000013123 dwarf bean Species 0.000 description 1
235000013399 edible fruits Nutrition 0.000 description 1
230000007613 environmental effect Effects 0.000 description 1
239000011888 foil Substances 0.000 description 1
238000009472 formulation Methods 0.000 description 1
230000002496 gastric effect Effects 0.000 description 1
238000010562 histological examination Methods 0.000 description 1
238000000338 in vitro Methods 0.000 description 1
230000002757 inflammatory effect Effects 0.000 description 1
150000002500 ions Chemical class 0.000 description 1
229910052742 iron Inorganic materials 0.000 description 1
235000020888 liquid diet Nutrition 0.000 description 1
244000144972 livestock Species 0.000 description 1
WPBNNNQJVZRUHP-UHFFFAOYSA-L manganese(2+);methyl n-[[2-(methoxycarbonylcarbamothioylamino)phenyl]carbamothioyl]carbamate;n-[2-(sulfidocarbothioylamino)ethyl]carbamodithioate Chemical compound [Mn+2].[S-]C(=S)NCCNC([S-])=S.COC(=O)NC(=S)NC1=CC=CC=C1NC(=S)NC(=O)OC WPBNNNQJVZRUHP-UHFFFAOYSA-L 0.000 description 1
238000010297 mechanical methods and process Methods 0.000 description 1
230000005226 mechanical processes and functions Effects 0.000 description 1
230000007246 mechanism Effects 0.000 description 1
239000011785 micronutrient Substances 0.000 description 1
235000013369 micronutrients Nutrition 0.000 description 1
229910052750 molybdenum Inorganic materials 0.000 description 1
239000011733 molybdenum Substances 0.000 description 1
229910052757 nitrogen Inorganic materials 0.000 description 1
235000015097 nutrients Nutrition 0.000 description 1
235000016709 nutrition Nutrition 0.000 description 1
230000035764 nutrition Effects 0.000 description 1
206010033675 panniculitis Diseases 0.000 description 1
239000008188 pellet Substances 0.000 description 1
VSIIXMUUUJUKCM-UHFFFAOYSA-D pentacalcium;fluoride;triphosphate Chemical compound [F-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O VSIIXMUUUJUKCM-UHFFFAOYSA-D 0.000 description 1
239000000546 pharmaceutical excipient Substances 0.000 description 1
231100000614 poison Toxicity 0.000 description 1
230000002980 postoperative effect Effects 0.000 description 1
238000012545 processing Methods 0.000 description 1
229910052710 silicon Inorganic materials 0.000 description 1
239000010703 silicon Substances 0.000 description 1
238000010583 slow cooling Methods 0.000 description 1
238000004856 soil analysis Methods 0.000 description 1
238000009331 sowing Methods 0.000 description 1
210000004304 subcutaneous tissue Anatomy 0.000 description 1
208000024891 symptom Diseases 0.000 description 1
230000000699 topical effect Effects 0.000 description 1
231100000331 toxic Toxicity 0.000 description 1
231100000816 toxic dose Toxicity 0.000 description 1
230000002588 toxic effect Effects 0.000 description 1
239000003440 toxic substance Substances 0.000 description 1
238000005303 weighing Methods 0.000 description 1
230000004580 weight loss Effects 0.000 description 1
239000011701 zinc Substances 0.000 description 1
229910052725 zinc Inorganic materials 0.000 description 1

Classifications

- C—CHEMISTRY; METALLURGY
- C03—GLASS; MINERAL OR SLAG WOOL
- C03C—CHEMICAL COMPOSITION OF GLASSES, GLAZES OR VITREOUS ENAMELS; SURFACE TREATMENT OF GLASS; SURFACE TREATMENT OF FIBRES OR FILAMENTS MADE FROM GLASS, MINERALS OR SLAGS; JOINING GLASS TO GLASS OR OTHER MATERIALS
- C03C3/00—Glass compositions
- C03C3/12—Silica-free oxide glass compositions
- C03C3/16—Silica-free oxide glass compositions containing phosphorus
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/02—Inorganic materials
- A61L27/12—Phosphorus-containing materials, e.g. apatite
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/28—Materials for coating prostheses
- A61L27/30—Inorganic materials
- A61L27/32—Phosphorus-containing materials, e.g. apatite
- C—CHEMISTRY; METALLURGY
- C03—GLASS; MINERAL OR SLAG WOOL
- C03C—CHEMICAL COMPOSITION OF GLASSES, GLAZES OR VITREOUS ENAMELS; SURFACE TREATMENT OF GLASS; SURFACE TREATMENT OF FIBRES OR FILAMENTS MADE FROM GLASS, MINERALS OR SLAGS; JOINING GLASS TO GLASS OR OTHER MATERIALS
- C03C10/00—Devitrified glass ceramics, i.e. glass ceramics having a crystalline phase dispersed in a glassy phase and constituting at least 50% by weight of the total composition
- C—CHEMISTRY; METALLURGY
- C03—GLASS; MINERAL OR SLAG WOOL
- C03C—CHEMICAL COMPOSITION OF GLASSES, GLAZES OR VITREOUS ENAMELS; SURFACE TREATMENT OF GLASS; SURFACE TREATMENT OF FIBRES OR FILAMENTS MADE FROM GLASS, MINERALS OR SLAGS; JOINING GLASS TO GLASS OR OTHER MATERIALS
- C03C4/00—Compositions for glass with special properties
- C03C4/0007—Compositions for glass with special properties for biologically-compatible glass
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
- A61F2310/00005—The prosthesis being constructed from a particular material
- A61F2310/00179—Ceramics or ceramic-like structures
- A61F2310/00293—Ceramics or ceramic-like structures containing a phosphorus-containing compound, e.g. apatite
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
- A61F2310/00389—The prosthesis being coated or covered with a particular material
- A61F2310/00592—Coating or prosthesis-covering structure made of ceramics or of ceramic-like compounds
- A61F2310/00796—Coating or prosthesis-covering structure made of a phosphorus-containing compound, e.g. hydroxy(l)apatite

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Geochemistry & Mineralogy (AREA)
Materials Engineering (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Dermatology (AREA)
Veterinary Medicine (AREA)
Oral & Maxillofacial Surgery (AREA)
Transplantation (AREA)
Epidemiology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Inorganic Chemistry (AREA)
Molecular Biology (AREA)
Ceramic Engineering (AREA)
Crystallography & Structural Chemistry (AREA)
Dispersion Chemistry (AREA)
Glass Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Fertilizers (AREA)
Materials For Medical Uses (AREA)

DD33452489A 1989-11-13 1989-11-13 Glasiges oder glasig-kristallines Material mit schneller Loeslichkeit und Verfahren zu seiner Herstellung DD302011A9 (de)

Priority Applications (6)

Application Number	Priority Date	Filing Date	Title
DD33452489A DD302011A9 (de)	1989-11-13	1989-11-13	Glasiges oder glasig-kristallines Material mit schneller Loeslichkeit und Verfahren zu seiner Herstellung
AT90916242T ATE112540T1 (de)	1989-11-13	1990-11-12	Glasiges oder glasig-kristallines material mit schneller löslichkeit und verfahren zu seiner herstellung.
ES90916242T ES2064769T3 (es)	1989-11-13	1990-11-12	Material vitreo o vitreo-cristalino con solubilidad rapida y procedimiento para su produccion.
PCT/DE1990/000875 WO1991007357A1 (de)	1989-11-13	1990-11-12	Glasiges oder glasig-kristallines material mit schneller löslichkeit und verfahren zu seiner herstellung
DE59007405T DE59007405D1 (de)	1989-11-13	1990-11-12	Glasiges oder glasig-kristallines material mit schneller löslichkeit und verfahren zu seiner herstellung.
EP90916242A EP0541546B1 (de)	1989-11-13	1990-11-12	Glasiges oder glasig-kristallines material mit schneller löslichkeit und verfahren zu seiner herstellung

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DD33452489A DD302011A9 (de)	1989-11-13	1989-11-13	Glasiges oder glasig-kristallines Material mit schneller Loeslichkeit und Verfahren zu seiner Herstellung

Publications (1)

Publication Number	Publication Date
DD302011A9 true DD302011A9 (de)	1994-11-03

Family

ID=5613786

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DD33452489A DD302011A9 (de)	1989-11-13	1989-11-13	Glasiges oder glasig-kristallines Material mit schneller Loeslichkeit und Verfahren zu seiner Herstellung

Country Status (6)

Country	Link
EP (1)	EP0541546B1 (es)
AT (1)	ATE112540T1 (es)
DD (1)	DD302011A9 (es)
DE (1)	DE59007405D1 (es)
ES (1)	ES2064769T3 (es)
WO (1)	WO1991007357A1 (es)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE10308227A1 (de) *	2003-02-25	2004-09-09	Schott Glas	Antimikrobiell wirkendes Sulfophosphatglas
US8080490B2 (en)	2003-02-25	2011-12-20	Schott Ag	Antimicrobial phosphate glass

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5328874A (en) *	1993-10-18	1994-07-12	Corning Incorporated	Zinc sulfophosphate glasses
DE19508647C2 (de) *	1994-06-29	1999-06-02	Biovision Gmbh	Markraumsperre
DE19744809C1 (de) *	1997-10-02	1999-07-01	Georg Dr Berger	Poröser, glasig-kristalliner Formkörper mit schneller Löslichkeit, Verfahren zu seiner Herstellung und Verwendung
DE10129843A1 (de)	2001-06-15	2003-03-06	Bam Bundesanstalt Matforschung	Oberflächenbehandeltes metallisches Implantat und Strahlgut
US8168208B1 (en) *	2002-06-03	2012-05-01	Ahmed El-Ghannam	Silica-calcium phosphate bioactive composite for improved synthetic graft resorbability and tissue regeneration
DE10249625B4 (de) *	2002-10-21	2005-08-04	BAM Bundesanstalt für Materialforschung und -prüfung	Pulvergemisch für resorbierbare Calciumphosphat-Biozemente und ihre Verwendung
DE10249626B4 (de) *	2002-10-21	2005-07-07	BAM Bundesanstalt für Materialforschung und -prüfung	Knochenersatzwerkstoff mit kristallinen und Glasphasen und Verfahren zu seiner Herstellung sowie seine Verwendung
DE10261992B4 (de) *	2002-10-21	2006-01-26	BAM Bundesanstalt für Materialforschung und -prüfung	Verwendung eines Glases als Sinterhilfsmittel und offenporiger Formkörper sowie Verfahren zu seiner Herstellung
DE10249627B4 (de)	2002-10-21	2005-07-21	BAM Bundesanstalt für Materialforschung und -prüfung	Knochenersatzwerkstoff mit kristallinen und amorphen Phasen und Verfahren zu seiner Herstellung sowie seine Verwendung
DE10307646B3 (de) *	2003-02-21	2004-10-21	Ivoclar Vivadent Ag	Bioaktive Rhenanit-Glaskeramik, Verfahren zu ihrer Herstellung und ihre Verwendung
DE102005029206A1 (de)	2005-06-22	2006-12-28	Heraeus Kulzer Gmbh	Verformbares Implantatmaterial

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JPS5777038A (en) *	1980-10-28	1982-05-14	Asahi Glass Co Ltd	Manufacture of crystallized glass from phosphate glass

1989
- 1989-11-13 DD DD33452489A patent/DD302011A9/de not_active IP Right Cessation
1990
- 1990-11-12 DE DE59007405T patent/DE59007405D1/de not_active Expired - Fee Related
- 1990-11-12 EP EP90916242A patent/EP0541546B1/de not_active Expired - Lifetime
- 1990-11-12 ES ES90916242T patent/ES2064769T3/es not_active Expired - Lifetime
- 1990-11-12 AT AT90916242T patent/ATE112540T1/de not_active IP Right Cessation
- 1990-11-12 WO PCT/DE1990/000875 patent/WO1991007357A1/de not_active Ceased

Cited By (2)

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Publication number	Priority date	Publication date	Assignee	Title
DE10308227A1 (de) *	2003-02-25	2004-09-09	Schott Glas	Antimikrobiell wirkendes Sulfophosphatglas
US8080490B2 (en)	2003-02-25	2011-12-20	Schott Ag	Antimicrobial phosphate glass

Also Published As

Publication number	Publication date
EP0541546B1 (de)	1994-10-05
ES2064769T3 (es)	1995-02-01
ATE112540T1 (de)	1994-10-15
DE59007405D1 (de)	1994-11-10
EP0541546A1 (de)	1993-05-19
WO1991007357A1 (de)	1991-05-30

Legal Events

Date	Code	Title
1994-11-03	A9	Laid open application accord. to par. 10.3 extension act
1998-07-09	E491	Granted (sect. 49/1 patent act
1999-04-15	ENJ	Ceased due to non-payment of renewal fee

Publication	Publication Date	Title
DE69214005T2 (de)	1997-05-15	Erhärtende Zusammensetzungen zur Verwendung in der Medizin oder Zahnheilkunde
DE69010066T3 (de)	2006-11-09	Material und Verfahren zur Restauration eines Knochendefekts mittels Knochengewebe.
DE69533490T2 (de)	2005-01-20	Bioaktive granulate zur bildung von knochengewebe
EP1343452B1 (de)	2005-03-02	Reaktionsträges dentalglas
DE10307646B3 (de)	2004-10-21	Bioaktive Rhenanit-Glaskeramik, Verfahren zu ihrer Herstellung und ihre Verwendung
EP0541546B1 (de)	1994-10-05	Glasiges oder glasig-kristallines material mit schneller löslichkeit und verfahren zu seiner herstellung
DE102004050095A1 (de)	2005-05-19	Ca0-Mg0-Si02-basiertes, biologisch aktives Glas und gesintertes Calciumphosphat-Glas
DE10332086A1 (de)	2004-01-29	Ca0-Si02-basiertes bioaktives Glas und gesintertes Calciumphosphat-Glas
WO2003050051A1 (de)	2003-06-19	Antimikrobielle alkali-silicat-glaskeramik und ihre verwendung
EP1395300A1 (de)	2004-03-10	Oberflächenbehandeltes metallisches implantat und strahlgut
DD247888A1 (de)	1987-07-22	Phosphatglaskeramik
DE19744809C1 (de)	1999-07-01	Poröser, glasig-kristalliner Formkörper mit schneller Löslichkeit, Verfahren zu seiner Herstellung und Verwendung
EP1413320B1 (de)	2006-07-05	Pulvergemisch für resorbierbare Calciumphosphat-Biozemente
DE3306648A1 (de)	1983-09-22	Maschinell bearbeitbare bioaktive glaskeramik
DE4113021A1 (de)	1992-10-22	Resorbierbare phosphatglaeser und resorbierbare phosphatglaskeramiken und verfahren zu ihrer herstellung
EP1413321B1 (de)	2006-01-04	Phosphathaltiger Knochenersatzwerkstoff mit kristallinen und röntgenamorphen Phasen
EP2976311B1 (de)	2020-12-23	Sinter- und/oder schmelzfähige keramische masse, deren herstellung und verwendung
EP0237043B1 (de)	1992-06-03	Calciumphosphathaltiger, biokompatibler Schichtkörper und Verfahren zu seiner Herstellung
EP1266874B1 (de)	2004-09-22	Glasig-kristallines Material mit geringer Löslichkeit und Verfahren zu seiner Herstellung
EP1413322B1 (de)	2006-07-05	Phosphathaltiger Knochenersatzwerkstoff mit kristallinen und röntgenamorphen Phasen
DE10249626B4 (de)	2005-07-07	Knochenersatzwerkstoff mit kristallinen und Glasphasen und Verfahren zu seiner Herstellung sowie seine Verwendung
DD295981A5 (de)	1991-11-21	Verfahren zur herstellung eines materials mit angekoppelten wirkstoffen sowie das damit hergestellte material
DD295982A5 (de)	1991-11-21	Verfahren zur herstellung eines resorbierbaren materials mit angekoppeltem wirkstoff sowie des damit hergestellte material
EP0119403B1 (de)	1989-06-07	Bioaktives Implantatmaterial
DD296066A5 (de)	1991-11-21	Verfahren zur herstellung eines sinterglaskeramischen resorbierbaren formkoerpers und damit hergestellte produkte

DD302011A9 - Glasiges oder glasig-kristallines Material mit schneller Loeslichkeit und Verfahren zu seiner Herstellung - Google Patents

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