DE69433115D1 - Verfahren zur isolierung von cda-präsentierten antigenen, cd1-präsentierte antigeneenthaltende impfstoffe und in besagten verfahren verwendbare zelllinien - Google Patents

Verfahren zur isolierung von cda-präsentierten antigenen, cd1-präsentierte antigeneenthaltende impfstoffe und in besagten verfahren verwendbare zelllinien

Info

Publication number
DE69433115D1
DE69433115D1 DE69433115T DE69433115T DE69433115D1 DE 69433115 D1 DE69433115 D1 DE 69433115D1 DE 69433115 T DE69433115 T DE 69433115T DE 69433115 T DE69433115 T DE 69433115T DE 69433115 D1 DE69433115 D1 DE 69433115D1
Authority
DE
Germany
Prior art keywords
presented
methods
antigens
antigen
isolating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69433115T
Other languages
English (en)
Other versions
DE69433115T2 (de
Inventor
Steven A Porcelli
Michael B Brenner
Evan Beckman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
The Brigham and Women's Hospital Inc
Original Assignee
The Brigham and Women's Hospital Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Brigham and Women's Hospital Inc filed Critical The Brigham and Women's Hospital Inc
Publication of DE69433115D1 publication Critical patent/DE69433115D1/de
Application granted granted Critical
Publication of DE69433115T2 publication Critical patent/DE69433115T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70539—MHC-molecules, e.g. HLA-molecules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/04—Mycobacterium, e.g. Mycobacterium tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cell Biology (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE69433115T 1993-06-21 1994-06-21 Verfahren zur isolierung von cda-präsentierten antigenen, cd1-präsentierte antigeneenthaltende impfstoffe und in besagten verfahren verwendbare zelllinien Expired - Fee Related DE69433115T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US8007293A 1993-06-21 1993-06-21
US80072 1993-06-21
PCT/US1994/006991 WO1995000163A1 (en) 1993-06-21 1994-06-21 Methods of isolating cd1-presented antigens, vaccines comprising cd1-presented antigens, and cell lines for use in said methods

Publications (2)

Publication Number Publication Date
DE69433115D1 true DE69433115D1 (de) 2003-10-09
DE69433115T2 DE69433115T2 (de) 2004-04-01

Family

ID=22155084

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69433115T Expired - Fee Related DE69433115T2 (de) 1993-06-21 1994-06-21 Verfahren zur isolierung von cda-präsentierten antigenen, cd1-präsentierte antigeneenthaltende impfstoffe und in besagten verfahren verwendbare zelllinien

Country Status (8)

Country Link
EP (1) EP0751780B1 (de)
JP (2) JPH08511939A (de)
AT (1) ATE248602T1 (de)
CA (1) CA2165786A1 (de)
DE (1) DE69433115T2 (de)
DK (1) DK0751780T3 (de)
ES (1) ES2201078T3 (de)
WO (1) WO1995000163A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6238676B1 (en) 1992-12-10 2001-05-29 Brigham And Women's Hospital Presentation of hydrophobic antigens to T-cells by CD1 molecules
US7063844B2 (en) 1992-12-10 2006-06-20 The Brigham And Women's Hospital, Inc. Presentation of hydrophobic antigens to T-cells by CD1 molecules
JPH09512101A (ja) * 1994-04-14 1997-12-02 アドコック、イングラム、リミテッド Ｍｙｃｏｂａｃｔｅｒｉｕｍ種の存在の検出法およびその方法に用いられるキットおよび抗体
CA2202680A1 (en) * 1994-10-13 1996-04-25 Robert L. Modlin Presentation of hydrophobic antigens to t-cells by cd1 molecules
HUP9900378A3 (en) * 1995-02-22 1999-11-29 Adcock Ingram Ltd A method for the isolation and purification of lipid cell-wall components
US6805861B2 (en) * 1996-01-17 2004-10-19 Imperial College Innovations Limited Immunotherapy using cytotoxic T lymphocytes (CTL)
WO1998039025A2 (en) 1997-03-03 1998-09-11 Adcock Ingram Limited A composition comprising a carrier and a purified mycobacterial lipid cell-wall component and its use in the prevention, treatment and diagnosis of disease
CA2441893C (en) 2001-03-26 2015-01-20 Dana-Farber Cancer Institute, Inc. Method of attenuating reactions to skin irritants
WO2004093903A2 (en) * 2003-04-18 2004-11-04 The Brigham And Women's Hospital, Inc. Methods and compositions for immunomodulation using cd1 antigens
ATE539757T1 (de) 2004-11-02 2012-01-15 Univ Leland Stanford Junior Verfahren zur hemmung von nkt-zellen
EP2047860A1 (de) * 2007-10-12 2009-04-15 Centre National De La Recherche Scientifique (Cnrs) Pharmazeutische Zusammensetzungen mit Actinomycet-Glycerin-Acyl-Derivat-Antigenen, Verfahren zu deren Extraktion und ihre Verwendung gegen Tuberkulose
MX386714B (es) 2015-01-27 2025-03-11 Lava Therapeutics N V Anticuerpos de dominio simple dirigidos al grupo de diferenciación 1d (cd1d).
JP7457007B2 (ja) 2018-09-19 2024-03-27 ラヴァ・セラピューティクス・エヌ・ヴイ 二重作用ＣＤ１ｄ免疫グロブリン

Also Published As

Publication number Publication date
EP0751780A4 (de) 1997-12-10
CA2165786A1 (en) 1995-01-05
ATE248602T1 (de) 2003-09-15
JPH08511939A (ja) 1996-12-17
DK0751780T3 (da) 2003-10-13
ES2201078T3 (es) 2004-03-16
WO1995000163A1 (en) 1995-01-05
JP2006104206A (ja) 2006-04-20
EP0751780B1 (de) 2003-09-03
EP0751780A1 (de) 1997-01-08
DE69433115T2 (de) 2004-04-01

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Legal Events

Date Code Title Description
8339 Ceased/non-payment of the annual fee