DE69513393D1 - Verfahren und einrichtung zur zählung von zellen und mikroorganismen, im besonderen in lebensmitteln und biologischen flüssigkeiten - Google Patents

Verfahren und einrichtung zur zählung von zellen und mikroorganismen, im besonderen in lebensmitteln und biologischen flüssigkeiten

Info

Publication number
DE69513393D1
DE69513393D1 DE69513393T DE69513393T DE69513393D1 DE 69513393 D1 DE69513393 D1 DE 69513393D1 DE 69513393 T DE69513393 T DE 69513393T DE 69513393 T DE69513393 T DE 69513393T DE 69513393 D1 DE69513393 D1 DE 69513393D1
Authority
DE
Germany
Prior art keywords
microorganisms
food
counting cells
biological liquids
liquids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69513393T
Other languages
English (en)
Inventor
Jean-Claude Bisconte
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biocom SA
Original Assignee
Biocom SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biocom SA filed Critical Biocom SA
Application granted granted Critical
Publication of DE69513393D1 publication Critical patent/DE69513393D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
    • C12Q1/06Quantitative determination
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/30Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
    • C12M41/36Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of biomass, e.g. colony counters or by turbidity measurements
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/6428Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/6428Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G01N2021/6439Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/808Optical sensing apparatus
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/25Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25375Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Sustainable Development (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Optics & Photonics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
DE69513393T 1994-05-05 1995-05-03 Verfahren und einrichtung zur zählung von zellen und mikroorganismen, im besonderen in lebensmitteln und biologischen flüssigkeiten Expired - Lifetime DE69513393D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9405551A FR2719602B1 (fr) 1994-05-05 1994-05-05 Procédé et installation pour la numérisation de cellules et micro-organismes, notamment des produits alimentaires ou des fluides biologiques.
PCT/FR1995/000575 WO1995030768A1 (fr) 1994-05-05 1995-05-03 Procede et installation pour la numeration de cellules et micro-organismes, notamment des produits alimentaires ou des fluides biologiques

Publications (1)

Publication Number Publication Date
DE69513393D1 true DE69513393D1 (de) 1999-12-23

Family

ID=9462932

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69513393T Expired - Lifetime DE69513393D1 (de) 1994-05-05 1995-05-03 Verfahren und einrichtung zur zählung von zellen und mikroorganismen, im besonderen in lebensmitteln und biologischen flüssigkeiten

Country Status (6)

Country Link
US (1) US5976892A (de)
EP (1) EP0758400B1 (de)
JP (1) JPH09512713A (de)
DE (1) DE69513393D1 (de)
FR (1) FR2719602B1 (de)
WO (1) WO1995030768A1 (de)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3270722B2 (ja) * 1996-09-27 2002-04-02 オルガノ株式会社 細菌の検出方法及び検出装置
AU4412900A (en) * 2000-05-04 2001-11-12 Jean-Claude Bisconte De Saint-Julien Cell control in milk or blood
US6803208B2 (en) * 2001-07-30 2004-10-12 The United States Of America As Represented By The Secretary Of The Navy Automated epifluorescence microscopy for detection of bacterial contamination in platelets
CN100436574C (zh) * 2001-09-06 2008-11-26 基因描绘系统有限公司 复制细胞的快速检测
US6696269B2 (en) * 2002-03-28 2004-02-24 Giles Scientific, Inc. Microbiological testing method and related apparatus with diffuse-white light emitting diodes
JP2005528907A (ja) * 2002-06-07 2005-09-29 ミリポア・コーポレイション 液体試料の実地検査のための微生物用キットおよび方法
NL1021258C2 (nl) * 2002-08-12 2004-02-17 Tno Werkwijze en inrichting voor het bepalen van het aantal levende cellen in een testvloeistof en toepassing daarvan.
WO2004023099A2 (en) * 2002-09-07 2004-03-18 Arizona Board Of Regents Nanoengineered biophotonic hybrid device
US8173407B2 (en) * 2002-09-07 2012-05-08 Labelle Jeffrey T Nanoengineered biophotonic hybrid device
US9034623B2 (en) 2002-09-07 2015-05-19 Jeffrey T. LaBelle Nanoengineered biophotonic hybrid device
WO2005008226A1 (en) * 2003-07-19 2005-01-27 Digital Bio Technology Device for counting micro particles
KR100608498B1 (ko) * 2003-07-19 2006-08-08 주식회사 디지탈바이오테크놀러지 미세입자 계수 장치
US7796266B2 (en) 2004-04-30 2010-09-14 Kimberly-Clark Worldwide, Inc. Optical detection system using electromagnetic radiation to detect presence or quantity of analyte
US20050244953A1 (en) * 2004-04-30 2005-11-03 Kimberly-Clark Worldwide, Inc. Techniques for controlling the optical properties of assay devices
US7815854B2 (en) 2004-04-30 2010-10-19 Kimberly-Clark Worldwide, Inc. Electroluminescent illumination source for optical detection systems
WO2007014188A2 (en) * 2005-07-25 2007-02-01 Duke University Methods, systems, and computer program products for optimization of probes for spectroscopic measurement in turbid media
CN101528912B (zh) 2005-09-26 2014-08-27 快速微型生物系统公司 包含生长培养基的盒
US20080241935A1 (en) * 2007-03-27 2008-10-02 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Methods for pathogen detection
US7818154B2 (en) * 2006-03-17 2010-10-19 Duke University Monte Carlo based model of fluorescence in turbid media and methods and systems for using same to determine intrinsic fluorescence of turbid media
WO2007126827A2 (en) * 2006-03-30 2007-11-08 Duke University Optical assay system for intraoperative assessment of tumor margins
US20080270091A1 (en) * 2007-02-23 2008-10-30 Nirmala Ramanujam Scaling method for fast monte carlo simulation of diffuse reflectance spectra from multi-layered turbid media and methods and systems for using same to determine optical properties of multi-layered turbid medium from measured diffuse reflectance
US20090215157A1 (en) * 2007-03-27 2009-08-27 Searete Llc Methods for pathogen detection
WO2009036956A1 (en) * 2007-09-19 2009-03-26 University Of Bern Detection of staphylococcus aureus in bovine mastitic milk
US20110059016A1 (en) * 2007-09-27 2011-03-10 Nirmala Ramanujam Optical assay system with a multi-probe imaging array
US9820655B2 (en) * 2007-09-28 2017-11-21 Duke University Systems and methods for spectral analysis of a tissue mass using an instrument, an optical probe, and a Monte Carlo or a diffusion algorithm
US20100189338A1 (en) * 2008-04-09 2010-07-29 Nexcelom Bioscience Systems and methods for counting cells and biomolecules
US20110105865A1 (en) * 2008-04-24 2011-05-05 Duke University Diffuse reflectance spectroscopy device for quantifying tissue absorption and scattering
EP2340300B1 (de) 2008-09-24 2013-12-18 Straus Holdings Inc. Verfahren zur erkennung von analyten
CA2854000C (en) 2011-11-07 2023-01-24 Rapid Micro Biosystems, Inc. A cell culturing device allowing filtration therein
EP4060016A1 (de) 2012-04-16 2022-09-21 Rapid Micro Biosystems, Inc. Zellkultivierungsvorrichtung
EP3851832B1 (de) 2014-01-30 2024-01-17 BD Kiestra B.V. System und verfahren zur bilderfassung unter verwendung von überwachter hochwertiger bildgebung
CN105462824B (zh) * 2014-05-27 2021-02-02 Bd控股私人有限公司 在商业无菌检测中使用血培养基平台的改进
US10521910B2 (en) 2015-04-23 2019-12-31 Bd Kiestra B.V. Colony contrast gathering
KR102643990B1 (ko) 2015-04-23 2024-03-05 비디 키에스트라 비.브이. 플레이팅된 배지 상의 스트리킹된 샘플로부터 자동화된 미생물 콜로니 카운트를 위한 방법 및 시스템
JP7347849B2 (ja) 2018-04-19 2023-09-20 ファースト ライト ダイアグノスティクス, インコーポレイテッド 標的の検出
US20210349082A1 (en) 2018-10-04 2021-11-11 First Light Diagnostics, Inc. Analysis instrument
WO2021144321A1 (en) * 2020-01-15 2021-07-22 Société des Produits Nestlé SA Detection of plastic microparticles in a milk based sample by flow cytometry

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0148290A1 (de) * 1983-12-14 1985-07-17 Försvarets Forskningsanstalt Verfahren und Vorrichtung zur Analyse von flüssigen Proben
FR2628531B1 (fr) * 1988-03-08 1992-10-02 Chemunex Sa Procede de recherche, de detection specifique et de numeration de micro-organismes, installation pour la mise en oeuvre dudit procede
FR2636646B1 (fr) * 1988-09-19 1990-12-21 Tepral Sa Procede de detection specifique et de denombrement des micro-organismes dans des produits filtrables
FR2638101B1 (fr) * 1988-10-21 1991-09-06 Biocom Sa Dispositif de filtration parallele d'une pluralite d'echantillons avec controle automatique des volumes filtres et du colmatage ainsi qu'avec indexation du filtre, et procede de filtration
FR2646914A1 (fr) * 1989-05-12 1990-11-16 Leca Procede et dispositif d'identification et de numerisation de cellules dans du lait
EP0405480A3 (en) * 1989-06-28 1991-05-08 Kirin Beer Kabushiki Kaisha Method of and apparatus for detecting microorganisms
US5480804A (en) * 1989-06-28 1996-01-02 Kirin Beverage Corporation Method of and apparatus for detecting microorganisms
FR2657543B1 (fr) * 1990-01-26 1992-12-18 Biocom Sa Dispositif modulaire pour le recueil, l'incubation, la filtration d'echantillons multiples.
EP0443700A3 (en) * 1990-02-21 1991-10-16 Mitsubishi Jukogyo Kabushiki Kaisha Method for counting living cells of microbes and apparatus therefor
JPH0728758B2 (ja) * 1990-07-11 1995-04-05 出光興産株式会社 微生物生菌数の迅速測定方法および測定キット
WO1992014838A1 (fr) * 1991-02-13 1992-09-03 Nihon Millipore Kogyo Kabushiki Kaisha Procede de determination quantitative de micro-organismes viables
JP3102938B2 (ja) * 1991-12-30 2000-10-23 シスメックス株式会社 粒子画像分析装置

Also Published As

Publication number Publication date
JPH09512713A (ja) 1997-12-22
FR2719602B1 (fr) 1996-07-26
EP0758400A1 (de) 1997-02-19
WO1995030768A1 (fr) 1995-11-16
FR2719602A1 (fr) 1995-11-10
EP0758400B1 (de) 1999-11-17
US5976892A (en) 1999-11-02

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Legal Events

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8332 No legal effect for de