DE69534747D1 - Haemophilus influenzae (nt hi) lkp tip adhesin protein und nukleinsäure - Google Patents

Haemophilus influenzae (nt hi) lkp tip adhesin protein und nukleinsäure

Info

Publication number
DE69534747D1
DE69534747D1 DE69534747T DE69534747T DE69534747D1 DE 69534747 D1 DE69534747 D1 DE 69534747D1 DE 69534747 T DE69534747 T DE 69534747T DE 69534747 T DE69534747 T DE 69534747T DE 69534747 D1 DE69534747 D1 DE 69534747D1
Authority
DE
Germany
Prior art keywords
protein
haemophilus influenzae
pili
relates
adhesine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69534747T
Other languages
English (en)
Other versions
DE69534747T2 (de
Inventor
A Green
C Brinton
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth Holdings LLC
Wyeth LLC
Bactex Inc
Original Assignee
Wyeth Holdings LLC
Wyeth LLC
Bactex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/277,231 external-priority patent/US5643725A/en
Priority claimed from US08/473,750 external-priority patent/US5834187A/en
Priority claimed from US08/477,326 external-priority patent/US5968769A/en
Application filed by Wyeth Holdings LLC, Wyeth LLC, Bactex Inc filed Critical Wyeth Holdings LLC
Application granted granted Critical
Publication of DE69534747D1 publication Critical patent/DE69534747D1/de
Publication of DE69534747T2 publication Critical patent/DE69534747T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/285—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pasteurellaceae (F), e.g. Haemophilus influenza
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Communicable Diseases (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Virology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Wood Science & Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Toxicology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
DE69534747T 1994-07-19 1995-07-13 Haemophilus influenzae (nt hi) lkp tip adhesin protein und nukleinsäure Expired - Lifetime DE69534747T2 (de)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US277231 1981-06-25
US08/277,231 US5643725A (en) 1994-07-19 1994-07-19 Sequence and analysis of LKP pilin structural genes and the LKP pili operon of nontypable haemophilus influenzae
US08/473,750 US5834187A (en) 1994-07-19 1995-06-07 Sequence and analysis of LKP pilin structural genes and the LKP pili operon of nontypable Haemophilus influenzae
US08/477,326 US5968769A (en) 1994-07-19 1995-06-07 Sequence and analysis of LKP pilin structural genes and the LKP pili operon of nontypable Haemophilus influenzae
US477326 1995-06-07
PCT/US1995/008789 WO1996002648A1 (en) 1994-07-19 1995-07-13 Lkp pilin structural genes and operon of nontypable haemophilus influenzae
US473750 1999-12-28

Publications (2)

Publication Number Publication Date
DE69534747D1 true DE69534747D1 (de) 2006-04-06
DE69534747T2 DE69534747T2 (de) 2006-07-06

Family

ID=27402882

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69534747T Expired - Lifetime DE69534747T2 (de) 1994-07-19 1995-07-13 Haemophilus influenzae (nt hi) lkp tip adhesin protein und nukleinsäure

Country Status (11)

Country Link
EP (1) EP0771352B1 (de)
JP (2) JP2001521361A (de)
KR (1) KR100391483B1 (de)
AT (1) ATE315648T1 (de)
AU (1) AU706937B2 (de)
CA (1) CA2195090C (de)
DE (1) DE69534747T2 (de)
DK (1) DK0771352T3 (de)
ES (1) ES2257741T3 (de)
PT (1) PT771352E (de)
WO (1) WO1996002648A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001521361A (ja) * 1994-07-19 2001-11-06 アメリカン・サイアナミド・カンパニー 型別不能ハエモフィルス インフルエンザエ（ｈａｅｍｏｐｈｉｌｕｓ ｉｎｆｌｕｅｎｚａｅ）のｌｋｐピリン構造遺伝子およびオペロン
US6001564A (en) * 1994-09-12 1999-12-14 Infectio Diagnostic, Inc. Species specific and universal DNA probes and amplification primers to rapidly detect and identify common bacterial pathogens and associated antibiotic resistance genes from clinical specimens for routine diagnosis in microbiology laboratories
US20020055101A1 (en) 1995-09-11 2002-05-09 Michel G. Bergeron Specific and universal probes and amplification primers to rapidly detect and identify common bacterial pathogens and antibiotic resistance genes from clinical specimens for routine diagnosis in microbiology laboratories
AU754024B2 (en) * 1995-03-24 2002-10-31 St. Louis University Haemophilus adhesion proteins
US5646259A (en) * 1995-03-24 1997-07-08 St. Louis University DNA encoding haemophilus adhesion proteins
US5750116A (en) * 1995-06-02 1998-05-12 Bactex, Inc. Haemophilus influenzae pilus vaccines
US5994066A (en) * 1995-09-11 1999-11-30 Infectio Diagnostic, Inc. Species-specific and universal DNA probes and amplification primers to rapidly detect and identify common bacterial pathogens and associated antibiotic resistance genes from clinical specimens for routine diagnosis in microbiology laboratories
US20030049636A1 (en) 1999-05-03 2003-03-13 Bergeron Michel G. Species-specific, genus-specific and universal DNA probes and amplification primers to rapidly detect and identify common bacterial and fungal pathogens and associated antibiotic resistance genes from clinical specimens for diagnosis in microbiology laboratories
US20100267012A1 (en) 1997-11-04 2010-10-21 Bergeron Michel G Highly conserved genes and their use to generate probes and primers for detection of microorganisms
US6335182B1 (en) 1999-03-16 2002-01-01 Aventis Pasteur Limited Recombinant Haemophilus influenzae adhesin proteins
US7785609B1 (en) 1999-03-16 2010-08-31 Sanofi Pasteur Limited Recombinant Haemophilus influenzae adhesin proteins
EP1246935B1 (de) 1999-09-28 2013-08-14 Geneohm Sciences Canada Inc. Konservierte gene und dessen benutzung für die herstellung von sonden und primern für mikroorganismen nachweis
ATE557033T1 (de) 2003-12-23 2012-05-15 Nationwide Children S Hospital Inc Pili von haemophilus influenzae typ iv

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU3772389A (en) * 1988-06-16 1990-01-12 Bactex Inc. Haemophilus influenzae pilus vaccines
GB9205704D0 (en) * 1992-03-16 1992-04-29 Connaught Lab High molecular weight membrane proteins of non-typeable haemophilus
JP2001521361A (ja) * 1994-07-19 2001-11-06 アメリカン・サイアナミド・カンパニー 型別不能ハエモフィルス インフルエンザエ（ｈａｅｍｏｐｈｉｌｕｓ ｉｎｆｌｕｅｎｚａｅ）のｌｋｐピリン構造遺伝子およびオペロン

Also Published As

Publication number Publication date
AU706937B2 (en) 1999-07-01
ATE315648T1 (de) 2006-02-15
AU3097295A (en) 1996-02-16
EP0771352A1 (de) 1997-05-07
EP0771352B1 (de) 2006-01-11
JP2008067707A (ja) 2008-03-27
DK0771352T3 (da) 2006-03-06
KR100391483B1 (ko) 2003-10-30
ES2257741T3 (es) 2006-08-01
JP2001521361A (ja) 2001-11-06
CA2195090C (en) 2011-04-19
DE69534747T2 (de) 2006-07-06
CA2195090A1 (en) 1996-02-01
PT771352E (pt) 2006-05-31
WO1996002648A1 (en) 1996-02-01

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