DK0388619T3 - Fremgangsmåde til fremstilling af substituerede 2,3-pyridindicarboxylsyrer ved sekvensvis oxidation af substituerede quinoliner - Google Patents
Fremgangsmåde til fremstilling af substituerede 2,3-pyridindicarboxylsyrer ved sekvensvis oxidation af substituerede quinolinerInfo
- Publication number
- DK0388619T3 DK0388619T3 DK90102551.0T DK90102551T DK0388619T3 DK 0388619 T3 DK0388619 T3 DK 0388619T3 DK 90102551 T DK90102551 T DK 90102551T DK 0388619 T3 DK0388619 T3 DK 0388619T3
- Authority
- DK
- Denmark
- Prior art keywords
- substituted
- dicarboxylic acids
- quinolines
- pyridine dicarboxylic
- sequential oxidation
- Prior art date
Links
- 229940111121 antirheumatic drug quinolines Drugs 0.000 title abstract 2
- 230000003647 oxidation Effects 0.000 title abstract 2
- 238000007254 oxidation reaction Methods 0.000 title abstract 2
- 150000003248 quinolines Chemical class 0.000 title abstract 2
- GJAWHXHKYYXBSV-UHFFFAOYSA-N quinolinic acid Chemical class OC(=O)C1=CC=CN=C1C(O)=O GJAWHXHKYYXBSV-UHFFFAOYSA-N 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- WQYVRQLZKVEZGA-UHFFFAOYSA-N hypochlorite Inorganic materials Cl[O-] WQYVRQLZKVEZGA-UHFFFAOYSA-N 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
- C07D213/80—Acids; Esters in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/69—Two or more oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Quinoline Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US32694089A | 1989-03-22 | 1989-03-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0388619T3 true DK0388619T3 (da) | 1994-10-03 |
Family
ID=23274431
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK90102551.0T DK0388619T3 (da) | 1989-03-22 | 1990-02-09 | Fremgangsmåde til fremstilling af substituerede 2,3-pyridindicarboxylsyrer ved sekvensvis oxidation af substituerede quinoliner |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP0388619B1 (da) |
| JP (1) | JP2825596B2 (da) |
| KR (1) | KR0141483B1 (da) |
| CN (1) | CN1030569C (da) |
| AT (1) | ATE109772T1 (da) |
| CA (1) | CA2012558C (da) |
| DE (1) | DE69011367T2 (da) |
| DK (1) | DK0388619T3 (da) |
| ES (1) | ES2058625T3 (da) |
| IE (1) | IE66018B1 (da) |
| IL (1) | IL93394A (da) |
| ZA (1) | ZA902184B (da) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5206368A (en) * | 1991-03-12 | 1993-04-27 | American Cyanamid Company | Process for extracting pyridine- and quinolinedicarboxylic acids from aqueous media |
| DE69409776T2 (de) * | 1993-12-28 | 1998-09-24 | American Cyanamid Co | Verfahren zur Herstellung Pyridin-2,3-dicarboxylicsäure |
| US5686470A (en) * | 1995-02-10 | 1997-11-11 | Weier; Richard M. | 2, 3-substituted pyridines for the treatment of inflammation |
| NZ314904A (en) * | 1996-06-10 | 1998-06-26 | American Cyanamid Co | Preparation of a herbicidal [(5,6-dicarboxy-3-pyridyl)methyl]ammonium halide |
| NL1006596C2 (nl) * | 1997-07-16 | 1999-01-19 | Dsm Nv | Werkwijze voor de bereiding van 5-methoxymethylpyridine-2, 3-dicarbonzuur en derivaten daarvan. |
| US6174901B1 (en) | 1998-12-18 | 2001-01-16 | Amgen Inc. | Substituted pyridine and pyridazine compounds and methods of use |
| CN103193713A (zh) * | 2013-04-09 | 2013-07-10 | 常州博海威医药科技有限公司 | 一种制备2-丙级咪唑-4,5-二羧酸的方法 |
| CN105646120B (zh) * | 2014-12-02 | 2019-03-19 | 浙江省诸暨合力化学对外贸易有限公司 | 一种羧酸的制备方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4623726A (en) * | 1983-04-18 | 1986-11-18 | American Cyanamid Company | Method for oxidizing alkyl groups on pyridine, quinoline and benzene ring compounds to carboxylic acids under basic conditions |
| US4736036A (en) * | 1983-08-08 | 1988-04-05 | Appleton Papers Inc. | Process for the preparation of quinolinic acid |
| DE3345223A1 (de) * | 1983-12-14 | 1985-06-27 | Rütgerswerke AG, 6000 Frankfurt | Verfahren zur herstellung von chinolinsaeure aus chinolin |
| US4754039A (en) * | 1986-01-30 | 1988-06-28 | Ruetgers-Nease Chemical Co., Inc. | Process for the preparation of pyridine-2,3-dicarboxylic acid |
| ES2028834T3 (es) * | 1986-09-12 | 1992-07-16 | American Cyanamid Company | Metodo para la preparacion de accidos piridin-2,3-dicarboxilico. |
| IL89142A (en) | 1988-03-10 | 1993-04-04 | American Cyanamid Co | Method for the sequential oxidation of substituted 8-hydroxyquinolines to produce substituted pyridine-2,3- dicarboxylic acids |
-
1990
- 1990-02-09 EP EP90102551A patent/EP0388619B1/en not_active Expired - Lifetime
- 1990-02-09 DK DK90102551.0T patent/DK0388619T3/da active
- 1990-02-09 AT AT90102551T patent/ATE109772T1/de not_active IP Right Cessation
- 1990-02-09 ES ES90102551T patent/ES2058625T3/es not_active Expired - Lifetime
- 1990-02-09 DE DE69011367T patent/DE69011367T2/de not_active Expired - Lifetime
- 1990-02-14 IL IL9339490A patent/IL93394A/en not_active IP Right Cessation
- 1990-02-21 CN CN90100953A patent/CN1030569C/zh not_active Expired - Lifetime
- 1990-03-19 JP JP2067382A patent/JP2825596B2/ja not_active Expired - Fee Related
- 1990-03-20 CA CA002012558A patent/CA2012558C/en not_active Expired - Lifetime
- 1990-03-21 IE IE103090A patent/IE66018B1/en not_active IP Right Cessation
- 1990-03-21 ZA ZA902184A patent/ZA902184B/xx unknown
- 1990-03-21 KR KR1019900003824A patent/KR0141483B1/ko not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JP2825596B2 (ja) | 1998-11-18 |
| CN1045776A (zh) | 1990-10-03 |
| EP0388619A1 (en) | 1990-09-26 |
| KR900014320A (ko) | 1990-10-23 |
| DE69011367D1 (de) | 1994-09-15 |
| CN1030569C (zh) | 1995-12-27 |
| ES2058625T3 (es) | 1994-11-01 |
| ZA902184B (en) | 1991-11-27 |
| IE66018B1 (en) | 1995-11-29 |
| ATE109772T1 (de) | 1994-08-15 |
| CA2012558A1 (en) | 1990-09-22 |
| IL93394A0 (en) | 1990-11-29 |
| DE69011367T2 (de) | 1995-03-23 |
| CA2012558C (en) | 2001-04-03 |
| EP0388619B1 (en) | 1994-08-10 |
| KR0141483B1 (ko) | 1998-06-01 |
| JPH02286660A (ja) | 1990-11-26 |
| IL93394A (en) | 1994-08-26 |
| IE901030L (en) | 1990-09-22 |
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