DK0398207T3 - Stabil flydende form af 5-aminosalicylsyre - Google Patents

Stabil flydende form af 5-aminosalicylsyre

Info

Publication number: DK0398207T3
Authority: DK; Denmark
Prior art keywords: alkali; aminosalicylic acid; asa; solution; alkaline earth
Prior art date: 1989-05-15

Application number

DK90109011.8T

Other languages

Danish (da)

English (en)

Inventor

Carey B Bottom

Margaret N Kwoka

Original Assignee

Marion Merrell Dow Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-05-15

Filing date

1990-05-14

Publication date

1994-10-03

1990-05-14 Application filed by Marion Merrell Dow Inc filed Critical Marion Merrell Dow Inc

1994-10-03 Application granted granted Critical

1994-10-03 Publication of DK0398207T3 publication Critical patent/DK0398207T3/da

Links

KBOPZPXVLCULAV-UHFFFAOYSA-N mesalamine Chemical compound NC1=CC=C(O)C(C(O)=O)=C1 KBOPZPXVLCULAV-UHFFFAOYSA-N 0.000 title abstract 8
229960004963 mesalazine Drugs 0.000 title abstract 7
239000007788 liquid Substances 0.000 title 1
239000000243 solution Substances 0.000 abstract 4
239000003513 alkali Substances 0.000 abstract 3
150000001340 alkali metals Chemical class 0.000 abstract 3
229910052783 alkali metal Inorganic materials 0.000 abstract 2
229910052784 alkaline earth metal Inorganic materials 0.000 abstract 2
-1 alkaline earth metal salt Chemical class 0.000 abstract 2
229910001854 alkali hydroxide Inorganic materials 0.000 abstract 1
229910000272 alkali metal oxide Inorganic materials 0.000 abstract 1
229910001860 alkaline earth metal hydroxide Inorganic materials 0.000 abstract 1
239000003963 antioxidant agent Substances 0.000 abstract 1
230000003078 antioxidant effect Effects 0.000 abstract 1
239000007864 aqueous solution Substances 0.000 abstract 1
239000008139 complexing agent Substances 0.000 abstract 1
238000000354 decomposition reaction Methods 0.000 abstract 1
238000011065 in-situ storage Methods 0.000 abstract 1
229910052751 metal Inorganic materials 0.000 abstract 1
239000002184 metal Substances 0.000 abstract 1
231100000252 nontoxic Toxicity 0.000 abstract 1
230000003000 nontoxic effect Effects 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/60—Salicylic acid; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0031—Rectum, anus
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/186—Quaternary ammonium compounds, e.g. benzalkonium chloride or cetrimide
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Inorganic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Anti-Oxidant Or Stabilizer Compositions (AREA)

DK90109011.8T 1989-05-15 1990-05-14 Stabil flydende form af 5-aminosalicylsyre DK0398207T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US07/352,064 US5010069A (en)	1989-05-15	1989-05-15	Stable liquid form of 5-aminosalicylic acid

Publications (1)

Publication Number	Publication Date
DK0398207T3 true DK0398207T3 (da)	1994-10-03

Family

ID=23383642

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK90109011.8T DK0398207T3 (da)	1989-05-15	1990-05-14	Stabil flydende form af 5-aminosalicylsyre

Country Status (8)

Country	Link
US (1)	US5010069A (de)
EP (1)	EP0398207B1 (de)
JP (1)	JPH0347161A (de)
AT (1)	ATE109660T1 (de)
CA (1)	CA2016825A1 (de)
DE (1)	DE69011399T2 (de)
DK (1)	DK0398207T3 (de)
ES (1)	ES2062161T3 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1992016214A1 (en) *	1991-03-15	1992-10-01	Norwich Eaton Pharmaceuticals Inc.	The use of 5-aminosalicylic acid in the treatment of irritable bowel syndrome - diarrheal phase or type (ibs-d)
HU213229B (en) *	1991-06-07	1997-03-28	Byk Nederland Bv	Process for preparing enema preparation containing 5-aminosalicylic acid
FR2738150B1 (fr) *	1995-09-01	1997-10-31	Synthelabo	Utilisation de la sulphasalazine et de ses metabolites pour la fabrication d'un medicament utile dans le traitement de l'insuffisance veineuse et des ulceres veineux
IT1277663B1 (it) *	1995-09-28	1997-11-11	Crinos Industria Farmaco	Sospensioni acquose stabili di mesalazina per uso topico
US6326364B1 (en)	1999-02-08	2001-12-04	Cedars-Sinai Medical Center	Use of 5-aminosalicylates as antimicrobial agents
DK1313697T3 (da) *	2000-08-29	2006-04-10	Nobex Corp	Immunregulatoriske forbindelser, derivater deraf samt anvendelse deraf
JP3805646B2 (ja) *	2001-05-25	2006-08-02	久光メディカル株式会社	医薬液剤
US8048924B2 (en) *	2001-08-29	2011-11-01	Biocon Limited	Methods and compositions employing 4-aminophenylacetic acid compounds
US20040087527A1 (en) *	2002-10-31	2004-05-06	Day Brian J.	Methods for treatment of thiol-containing compound deficient conditions
KR20060090667A (ko) *	2003-09-22	2006-08-14	닛신 쿄린 세이야꾸 가부시끼가이샤	변색 개선된 5-아미노살리실산 고형 제제 및 그의 보존방법
AU2004314731B2 (en)	2004-01-20	2011-07-07	The Board Of Regents Of The University Of Oklahoma	Compositions and methods of treatment for inflammatory diseases
DK1773767T3 (en)	2004-07-07	2016-03-21	Biocon Ltd	Synthesis of azo bound in immune regulatory relations
US7645801B2 (en) *	2007-01-29	2010-01-12	Alaven Pharmaceutical Llc	Reduced irritant enema for treatment of inflammatory bowel disease (IBD)
KR101420315B1 (ko)	2014-03-19	2014-07-17	남봉길	약학적 액제 조성물
US20160263152A1 (en) *	2015-03-14	2016-09-15	Gavis Pharmaceuticals	Bowel cleansing composition with improved taste
TW201804996A (zh) *	2016-07-08	2018-02-16	輝凌責任有限公司	含有匹可硫酸鹽(picosulfate)之安定液體調配物
CN113350277A (zh) *	2021-06-30	2021-09-07	广东科伦药业有限公司	一种治疗化疗口腔黏膜炎的美沙拉秦含漱液及其制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2647853A (en) *	1949-11-29	1953-08-04	Lab Francais Chimiotherapie	Injectable solution of salt of para-aminosalicylic acid
JPS57500432A (de) *	1980-03-20	1982-03-11
DE3151196A1 (de) *	1981-12-23	1983-06-30	Kurt Heinz Prof. Dr. 7800 Freiburg Bauer	Verfahren zur herstellung von gut loeslichen 5-aminosalicylsaeure-arzneimittelzubereitungen
US4664256A (en) *	1983-09-06	1987-05-12	Farmaceutisk Laboratorium Ferring A/S	Packaged stable enema solution or suspension containing 5-aminosalicyclic acid
US4657900A (en) *	1983-09-27	1987-04-14	Rowell Laboratories	Pharmaceutical article of manufacture comprising a bisulfite stabilized aqueous solution of 5-aminosalicylic acid and method
DK536987A (da) *	1987-10-14	1989-04-15	Ferring Farma Lab	Anvendelse af 5-aminosalicylsyre (5-asa) til fremstilling af et farmaceutisk praeparat til anvendelse ved reperfusionsbehandling

1989
- 1989-05-15 US US07/352,064 patent/US5010069A/en not_active Expired - Fee Related
1990
- 1990-05-14 AT AT90109011T patent/ATE109660T1/de not_active IP Right Cessation
- 1990-05-14 ES ES90109011T patent/ES2062161T3/es not_active Expired - Lifetime
- 1990-05-14 DK DK90109011.8T patent/DK0398207T3/da active
- 1990-05-14 DE DE69011399T patent/DE69011399T2/de not_active Expired - Fee Related
- 1990-05-14 EP EP90109011A patent/EP0398207B1/de not_active Expired - Lifetime
- 1990-05-14 JP JP2121424A patent/JPH0347161A/ja active Pending
- 1990-05-15 CA CA002016825A patent/CA2016825A1/en not_active Abandoned

Also Published As

Publication number	Publication date
ES2062161T3 (es)	1994-12-16
JPH0347161A (ja)	1991-02-28
ATE109660T1 (de)	1994-08-15
US5010069A (en)	1991-04-23
EP0398207A1 (de)	1990-11-22
DE69011399D1 (de)	1994-09-15
CA2016825A1 (en)	1990-11-15
EP0398207B1 (de)	1994-08-10
DE69011399T2 (de)	1994-12-15

Publication	Publication Date	Title
DK0398207T3 (da)	1994-10-03	Stabil flydende form af 5-aminosalicylsyre
BR8700386A (pt)	1987-12-08	Composicoes acidas pseudoplasticas
ATE41445T1 (de)	1989-04-15	Bleichmittelzusammensetzungen.
DE59106598D1 (de)	1995-11-02	Hochkonzentrierte pasten von alpha-sulfofettsäurealkylester-alkalimetallsalzen.
NO883716D0 (no)	1988-08-19	Tiksotrope, vandige suspensjoner av leire inneholdende alkalimetallsalt av fettsyre som stabiliseringsmiddel.
FI960327A0 (fi)	1996-01-24	Alumiinisuolaliuosten valmistusmenetelmä
ES2036566T3 (es)	1993-06-01	Solucion conteniendo cloruro de lisocima y gliciricinato dipotasico.
MX171381B (es)	1993-10-21	Proceso y composicion para inhibir la decoloracion de pinturas y bases para pintura
SE7714473L (sv)	1978-07-14	Lagringsbar blandning som vid upplosning i vatten ger en losning med hog antimikrobiell verkan
GB1320449A (en)	1973-06-13	T2-phosphonobutane 1,2,4-tricarboxylic acid compounds process for their preparation and their use as complex formers
DE3266150D1 (en)	1985-10-17	Dialdehyde containing compositions
GB1002503A (en)	1965-08-25	Compound having a vitamin k activity
DE3264314D1 (en)	1985-07-25	Fungicidal agent
IE791733L (en)	1980-03-14	Calf milk replacer
SE8002598L (sv)	1980-10-05	Silver- och silver/guld-pleteringsbad
NO850913L (no)	1985-09-09	Farmasoeytisk sammensetning, inneholdende azapropazon
WO1987006361A3 (en)	1988-03-24	Photographic bleach-fixing compositions
JPS574997A (en)	1982-01-11	Platina compound and its drug composition
GB1165098A (en)	1969-09-24	Improvements in the Preparation of Chlorine-Producing Bactericidal Compositions
JPS5528954A (en)	1980-02-29	Stabilization of alkaline aqueous solution of dioxythiourea
GB973112A (en)	1964-10-21	Complex salts of dichlorocyanuric acid and the preparation thereof
DE3673099D1 (de)	1990-09-06	Alkalivertraegliche amphoterische sulfobetain-tenside.
GB2012263A (en)	1979-07-25	Aldehyde adducts
GB8500108D0 (en)	1985-02-13	Disinfectant compositions
CA2026575A1 (en)	1990-08-16	Stable sodium tetraphenylborate solutions