DK0399685T3 - Isolering og strukturbestemmelse af de cytostatiske lineære depsipeptider dolastatin 13 og dehydrodolastatin 13 - Google Patents

Isolering og strukturbestemmelse af de cytostatiske lineære depsipeptider dolastatin 13 og dehydrodolastatin 13

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Publication number
DK0399685T3
DK0399685T3 DK90304859.3T DK90304859T DK0399685T3 DK 0399685 T3 DK0399685 T3 DK 0399685T3 DK 90304859 T DK90304859 T DK 90304859T DK 0399685 T3 DK0399685 T3 DK 0399685T3
Authority
DK
Denmark
Prior art keywords
dehydrodolastatin
dolastatin
depsipeptides
isolation
new
Prior art date
Application number
DK90304859.3T
Other languages
Danish (da)
English (en)
Inventor
Georges R Pettit
Yoshiaki Dr Kamano
Original Assignee
Univ Arizona State
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Publication date
Application filed by Univ Arizona State filed Critical Univ Arizona State
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Publication of DK0399685T3 publication Critical patent/DK0399685T3/da

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K11/00Depsipeptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K11/02Depsipeptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof cyclic, e.g. valinomycins ; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DK90304859.3T 1989-05-18 1990-05-04 Isolering og strukturbestemmelse af de cytostatiske lineære depsipeptider dolastatin 13 og dehydrodolastatin 13 DK0399685T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/353,960 US4986988A (en) 1989-05-18 1989-05-18 Isolation and structural elucidation of the cytostatic linear depsipeptides dolastatin 13 and dehydrodolastatin 13

Publications (1)

Publication Number Publication Date
DK0399685T3 true DK0399685T3 (da) 1993-10-25

Family

ID=23391329

Family Applications (1)

Application Number Title Priority Date Filing Date
DK90304859.3T DK0399685T3 (da) 1989-05-18 1990-05-04 Isolering og strukturbestemmelse af de cytostatiske lineære depsipeptider dolastatin 13 og dehydrodolastatin 13

Country Status (8)

Country Link
US (1) US4986988A (de)
EP (1) EP0399685B1 (de)
JP (1) JPH02311423A (de)
AT (1) ATE94170T1 (de)
CA (1) CA2013766A1 (de)
DE (1) DE69003168T2 (de)
DK (1) DK0399685T3 (de)
ES (1) ES2060035T3 (de)

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CA2013766A1 (en) 1990-11-18
ATE94170T1 (de) 1993-09-15
EP0399685A1 (de) 1990-11-28
DE69003168T2 (de) 1994-01-27
US4986988A (en) 1991-01-22
DE69003168D1 (de) 1993-10-14
ES2060035T3 (es) 1994-11-16
EP0399685B1 (de) 1993-09-08

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