DK0412822T3 - 4,4-Disubstituerede piperidinderivater, fremgangsmåder til deres fremstilling samt farmaceutiske præparater med indhold deraf - Google Patents

4,4-Disubstituerede piperidinderivater, fremgangsmåder til deres fremstilling samt farmaceutiske præparater med indhold deraf

Info

Publication number: DK0412822T3
Authority: DK; Denmark
Prior art keywords: alkyl; compounds; processes; preparation; pharmaceutical compositions
Prior art date: 1989-08-10

Application number

DK90308782.3T

Other languages

English (en)

Inventor

Eva Dr Palosi

Laszlo Dr Szporny

Edit Toth

Jozsef Toerley

Sandor Dr Goeroeg

Bela Kiss

Dora Dr Groo

Istvan Dr Laszlovszky

Erzsebet Dr Lapis

Ferenc Auth

Laszlo Dr Gaal

Original Assignee

Richter Gedeon Vegyeszet

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-08-10

Filing date

1990-08-09

Publication date

1994-05-16

1989-08-10 Priority claimed from HU894094A external-priority patent/HU204276B/hu

1990-08-09 Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet

1994-05-16 Application granted granted Critical

1994-05-16 Publication of DK0412822T3 publication Critical patent/DK0412822T3/da

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
- C07D211/48—Oxygen atoms attached in position 4 having an acyclic carbon atom attached in position 4

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Neurosurgery (AREA)
Life Sciences & Earth Sciences (AREA)
Biomedical Technology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Neurology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Hospice & Palliative Care (AREA)
Anesthesiology (AREA)
Otolaryngology (AREA)
Hydrogenated Pyridines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

DK90308782.3T 1989-08-10 1990-08-09 4,4-Disubstituerede piperidinderivater, fremgangsmåder til deres fremstilling samt farmaceutiske præparater med indhold deraf DK0412822T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
HU894094A HU204276B (en)	1989-08-10	1989-08-10	Process for producing new 1-oxa-2-oxo-4-methylen-8-aza-spiro(4,5)decane derivatives and pharmaceutical compositions containing them
HU323390		1990-05-29

Publications (1)

Publication Number	Publication Date
DK0412822T3 true DK0412822T3 (da)	1994-05-16

Family

ID=26317611

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK90308782.3T DK0412822T3 (da)	1989-08-10	1990-08-09	4,4-Disubstituerede piperidinderivater, fremgangsmåder til deres fremstilling samt farmaceutiske præparater med indhold deraf

Country Status (12)

Country	Link
US (1)	US5118693A (da)
EP (1)	EP0412822B1 (da)
JP (1)	JPH0377866A (da)
KR (1)	KR940003491B1 (da)
AT (1)	ATE103896T1 (da)
AU (1)	AU624261B2 (da)
DD (1)	DD299425A5 (da)
DE (1)	DE69007900T2 (da)
DK (1)	DK0412822T3 (da)
ES (1)	ES2063282T3 (da)
IL (1)	IL95323A (da)
NZ (1)	NZ234847A (da)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
HU204530B (en) *	1989-08-10	1992-01-28	Richter Gedeon Vegyeszet	Process for producing new 1-oxa-2-oxo-8-aza-spiro(4,5)decane derivatives and pharmaceutical compositions containing them
US5336675A (en) *	1991-05-14	1994-08-09	Ernir Snorrason	Method of treating mania in humans
SE9604786D0 (sv)	1996-12-20	1996-12-20	Astra Pharma Inc	New compounds
US6974825B1 (en)	1996-12-20	2005-12-13	Astrazeneca Canada Inc.	Compounds with analgesic effect
SE9904675D0 (sv)	1999-12-20	1999-12-20	Astra Pharma Inc	Novel compounds
US6656953B2 (en)	2000-12-06	2003-12-02	Sepracor Inc.	4,4-Disubstituted piperidines, and methods of use thereof
SE0101771D0 (sv)	2001-05-18	2001-05-18	Astrazeneca Ab	Novel compounds
SE0101773D0 (sv) *	2001-05-18	2001-05-18	Astrazeneca Ab	Novel compounds
SE0101770D0 (sv) *	2001-05-18	2001-05-18	Astrazeneca Ab	Novel compounds
SE0101769D0 (sv) *	2001-05-18	2001-05-18	Astrazeneca Ab	Novel compounds

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2838518A (en) *	1953-12-24	1958-06-10	Degussa	Ethynyl piperidyl carbamic acid esters
DE1137438B (de) *	1955-08-27	1962-10-04	Degussa	Verfahren zur Herstellung von sedativ bzw. hypnotisch wirksamen Carbaminsaeureestern
HU204529B (en) *	1989-08-10	1992-01-28	Richter Gedeon Vegyeszet	Process for producing new 1-oxa-2-oxo-8-aza-spiro(4,5)decane derivatives and pharmaceutical compositions containing them

1990
- 1990-08-08 KR KR1019900012170A patent/KR940003491B1/ko not_active Expired - Fee Related
- 1990-08-09 NZ NZ234847A patent/NZ234847A/en unknown
- 1990-08-09 AU AU60806/90A patent/AU624261B2/en not_active Ceased
- 1990-08-09 JP JP2209361A patent/JPH0377866A/ja active Pending
- 1990-08-09 DK DK90308782.3T patent/DK0412822T3/da active
- 1990-08-09 IL IL9532390A patent/IL95323A/en not_active IP Right Cessation
- 1990-08-09 ES ES90308782T patent/ES2063282T3/es not_active Expired - Lifetime
- 1990-08-09 EP EP90308782A patent/EP0412822B1/en not_active Expired - Lifetime
- 1990-08-09 DE DE69007900T patent/DE69007900T2/de not_active Expired - Fee Related
- 1990-08-09 DD DD90343364A patent/DD299425A5/de not_active IP Right Cessation
- 1990-08-09 AT AT90308782T patent/ATE103896T1/de not_active IP Right Cessation
- 1990-08-10 US US07/566,273 patent/US5118693A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
DE69007900T2 (de)	1994-07-21
JPH0377866A (ja)	1991-04-03
ES2063282T3 (es)	1995-01-01
KR940003491B1 (ko)	1994-04-23
KR910004563A (ko)	1991-03-28
IL95323A0 (en)	1991-06-30
NZ234847A (en)	1994-05-26
DE69007900D1 (de)	1994-05-11
US5118693A (en)	1992-06-02
IL95323A (en)	1994-06-24
EP0412822A3 (en)	1991-11-27
AU624261B2 (en)	1992-06-04
AU6080690A (en)	1991-02-14
EP0412822B1 (en)	1994-04-06
DD299425A5 (de)	1992-04-16
ATE103896T1 (de)	1994-04-15
EP0412822A2 (en)	1991-02-13

Publication	Publication Date	Title
PT88255A (pt)	1989-06-30	Processo para a preparacao de derivados do indole
PT91417A (pt)	1990-03-08	Processo para a preparacao de derivados indolicos
AU624261B2 (en)	1992-06-04	Novel 4,4-disubstituted piperidine derivatives, pharmaceutical compositions containing them and process for preparing the same
DE68918609D1 (de)	1994-11-10	Piperidinoalkyl-Derivate von Carbonsäure-Amiden.
PT94163A (pt)	1991-01-08	Processo para a preparacao de novas 2-aminotetralinas 8-substituidas e de composicoes farmaceuticas que as contem
ATE138653T1 (de)	1996-06-15	4-acylaminopyridin-derivate
ATE103921T1 (de)	1994-04-15	1-oxa-2-oxo-8-azaspiro(4,5>decan-derivate, verfahren zu ihrer herstellung und pharmazeutische zusammensetzungen daraus.
MX9205365A (es)	1993-03-01	Imidazolilmetil-piridinas y composicion farmaceutica que las contiene.
DE69005984D1 (de)	1994-02-24	2-Hydroxy-3-phenoxypropylaminoverbindungen.
NO171362C (no)	1993-03-03	Analogifremgangsmaate for fremstilling av nye aralkylaminforbindelser og deres salter
ATE113833T1 (de)	1994-11-15	Aromatische und heteroaromatische amine zur behandlung von depressionen, hirnleistungsstörungen und dementia.
DK0414421T3 (da)	1994-05-16	1-Oxa-2-oxo-8-azaspiro(4,5)decan-derivater, fremgangsmåder til deres fremstilling samt farmaceutiske præparater med indhold deraf
ATE149494T1 (de)	1997-03-15	Benzopyranderivate und verfahren zu deren herstellung