DK0413667T3 - Halogenalkylphenyl-alkoholer, ketoner og hydrater deraf - Google Patents

Halogenalkylphenyl-alkoholer, ketoner og hydrater deraf

Info

Publication number
DK0413667T3
DK0413667T3 DK90810608.1T DK90810608T DK0413667T3 DK 0413667 T3 DK0413667 T3 DK 0413667T3 DK 90810608 T DK90810608 T DK 90810608T DK 0413667 T3 DK0413667 T3 DK 0413667T3
Authority
DK
Denmark
Prior art keywords
haloalkylphenyl
hydrates
ketones
alcohols
therapeutics
Prior art date
Application number
DK90810608.1T
Other languages
English (en)
Inventor
Sylvain Cottens
Original Assignee
Sandoz Ag
Sandoz Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag, Sandoz Ltd filed Critical Sandoz Ag
Application granted granted Critical
Publication of DK0413667T3 publication Critical patent/DK0413667T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C225/00—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones
    • C07C225/22—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C215/22—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated
    • C07C215/28—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
    • C07C215/30—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings containing hydroxy groups and carbon atoms of six-membered aromatic rings bound to the same carbon atom of the carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C225/00—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones
    • C07C225/02—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C225/14—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being unsaturated
    • C07C225/16—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C225/00—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones
    • C07C225/20—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
DK90810608.1T 1989-08-16 1990-08-14 Halogenalkylphenyl-alkoholer, ketoner og hydrater deraf DK0413667T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3927049A DE3927049A1 (de) 1989-08-16 1989-08-16 Halogenalkyl-phenyl-ketone und deren hydrate, ihre herstellung und verwendung

Publications (1)

Publication Number Publication Date
DK0413667T3 true DK0413667T3 (da) 1993-11-08

Family

ID=6387229

Family Applications (1)

Application Number Title Priority Date Filing Date
DK90810608.1T DK0413667T3 (da) 1989-08-16 1990-08-14 Halogenalkylphenyl-alkoholer, ketoner og hydrater deraf

Country Status (18)

Country Link
US (1) US5166181A (da)
EP (1) EP0413667B1 (da)
JP (1) JPH03101643A (da)
KR (1) KR910004539A (da)
AT (1) ATE95166T1 (da)
AU (1) AU632844B2 (da)
CA (1) CA2023233A1 (da)
CZ (1) CZ411391A3 (da)
DE (2) DE3927049A1 (da)
DK (1) DK0413667T3 (da)
ES (1) ES2060127T3 (da)
FI (1) FI904025A7 (da)
HU (1) HUT58686A (da)
IE (1) IE902938A1 (da)
IL (1) IL95370A0 (da)
NZ (1) NZ234902A (da)
PT (1) PT94997A (da)
ZA (1) ZA906506B (da)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5336675A (en) * 1991-05-14 1994-08-09 Ernir Snorrason Method of treating mania in humans
EP0627400A1 (en) * 1993-06-04 1994-12-07 Merrell Dow Pharmaceuticals Inc. Aromatic acetylcholinesterase inhibitors
US6673784B1 (en) 1996-03-19 2004-01-06 G. D. Searle & Co. Electrophilic ketones for the treatment of herpesvirus infections
DE69715606T2 (de) * 1996-03-19 2003-05-08 G.D. Searle & Co., Chicago Elektrophile ketone zur behandlung von herpesvirus-infectionen
US6218383B1 (en) 1998-08-07 2001-04-17 Targacept, Inc. Pharmaceutical compositions for the prevention and treatment of central nervous system disorders
IT1304904B1 (it) 1998-09-11 2001-04-05 Eisai Co Ltd Derivati anticolinesterasici per il trattamento delle sindromidolorose funzionali e/o organiche
JP4639042B2 (ja) * 2003-09-29 2011-02-23 富士フイルムファインケミカルズ株式会社 ハロゲン−リチウム交換反応を用いる有機化合物の製造法
EP2044937A4 (en) 2006-07-05 2010-10-27 Tianjin Hemay Bio Tech Co Ltd ANALGESIC DERIVATIVES 5,9 - METHANOCYCLO OCTA (B) PYRIDINE - 2 (1H) - ONE, PROCESS FOR PREPARING SAME AND USE THEREOF
US20110212928A1 (en) 2010-02-09 2011-09-01 The Johns Hopkins University Methods and compositions for improving cognitive function
WO2014078568A1 (en) 2012-11-14 2014-05-22 The Johns Hopkins University Methods and compositions for treating schizophrenia
WO2014144663A1 (en) 2013-03-15 2014-09-18 The Johns Hopkins University Methods and compositions for improving cognitive function
EP2968220B1 (en) 2013-03-15 2021-05-05 Agenebio, Inc. Methods and compositions for improving cognitive function
NZ738682A (en) 2015-05-22 2022-01-28 Agenebio Inc Extended release pharmaceutical compositions of levetiracetam

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2840617A (en) * 1954-10-25 1958-06-24 Shell Dev New polyols, their preparation and derivatives
DE1934130A1 (de) * 1968-07-26 1970-01-29 Boehringer Sohn Ingelheim Acylphenylalkylamine und ihre Herstellung
US3996279A (en) * 1973-01-02 1976-12-07 Gerot-Pharmazeutika Dr. Walter Otto K.G. Novel 2-amino methyl-4,6-dihalogenphenol derivatives and methods for the preparation thereof
US4211794A (en) * 1979-01-08 1980-07-08 Pfizer Inc. N,N-Disubstituted aminomethylphenylethanolamines
JPS62252737A (ja) * 1986-04-01 1987-11-04 Japan Tobacco Inc アルデヒドまたはケトンのアルコールへの還元方法
EP0432719A1 (en) * 1989-12-14 1991-06-19 Hoechst-Roussel Pharmaceuticals Incorporated Alkylamino- and alkylaminoalkyl diarylketones, a process for their preparation and their use as medicaments

Also Published As

Publication number Publication date
AU6101590A (en) 1991-02-21
EP0413667B1 (de) 1993-09-29
IE902938A1 (en) 1991-02-27
CA2023233A1 (en) 1991-02-17
HUT58686A (en) 1992-03-30
EP0413667A1 (de) 1991-02-20
CZ411391A3 (en) 1994-01-19
FI904025A7 (fi) 1991-02-17
ATE95166T1 (de) 1993-10-15
HU904868D0 (en) 1991-01-28
KR910004539A (ko) 1991-03-28
IL95370A0 (en) 1991-06-30
FI904025A0 (fi) 1990-08-14
US5166181A (en) 1992-11-24
ZA906506B (en) 1992-04-29
NZ234902A (en) 1993-01-27
DE59002905D1 (de) 1993-11-04
AU632844B2 (en) 1993-01-14
PT94997A (pt) 1991-04-18
DE3927049A1 (de) 1991-02-21
JPH03101643A (ja) 1991-04-26
ES2060127T3 (es) 1994-11-16

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