DK0416069T3 - Leukotrien-B4derivater og fremgangsmåde til fremstilling deraf - Google Patents
Leukotrien-B4derivater og fremgangsmåde til fremstilling derafInfo
- Publication number
- DK0416069T3 DK0416069T3 DK90904600.5T DK90904600T DK0416069T3 DK 0416069 T3 DK0416069 T3 DK 0416069T3 DK 90904600 T DK90904600 T DK 90904600T DK 0416069 T3 DK0416069 T3 DK 0416069T3
- Authority
- DK
- Denmark
- Prior art keywords
- radical
- atoms
- group
- pct
- trans
- Prior art date
Links
- 150000002615 leukotriene B4 derivatives Chemical class 0.000 title abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 5
- 150000003254 radicals Chemical class 0.000 abstract 5
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 3
- -1 substituted alkyl radical Chemical class 0.000 abstract 3
- 229920000858 Cyclodextrin Polymers 0.000 abstract 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- CBOIHMRHGLHBPB-UHFFFAOYSA-N hydroxymethyl Chemical compound O[CH2] CBOIHMRHGLHBPB-UHFFFAOYSA-N 0.000 abstract 1
- 150000007524 organic acids Chemical class 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- HFHDHCJBZVLPGP-UHFFFAOYSA-N schardinger α-dextrin Chemical compound O1C(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(O)C2O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC2C(O)C(O)C1OC2CO HFHDHCJBZVLPGP-UHFFFAOYSA-N 0.000 abstract 1
- 125000003107 substituted aryl group Chemical group 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
- 239000011593 sulfur Substances 0.000 abstract 1
- 125000000383 tetramethylene group Chemical group [H]C([H])([*:1])C([H])([H])C([H])([H])C([H])([H])[*:2] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
- C07C43/23—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing hydroxy or O-metal groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
- C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
- C07C59/66—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
- C07C59/68—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE3909326A DE3909326A1 (de) | 1989-03-17 | 1989-03-17 | Neue leukotrien-b4-derivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0416069T3 true DK0416069T3 (da) | 1993-12-20 |
Family
ID=6376895
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK90904600.5T DK0416069T3 (da) | 1989-03-17 | 1990-03-16 | Leukotrien-B4derivater og fremgangsmåde til fremstilling deraf |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US5183925A (da) |
| EP (1) | EP0416069B1 (da) |
| JP (1) | JPH03505220A (da) |
| AT (1) | ATE92031T1 (da) |
| DE (2) | DE3909326A1 (da) |
| DK (1) | DK0416069T3 (da) |
| ES (1) | ES2058896T3 (da) |
| WO (1) | WO1990011272A1 (da) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4120698A1 (de) * | 1991-06-22 | 1992-12-24 | Gruenenthal Gmbh | Substituierte phenoxyalkanole und deren ester, diese verbindungen enthaltende arzneimittel und verfahren zur herstellung dieser verbindungen und arzneimittel |
| US8729108B2 (en) * | 2008-06-17 | 2014-05-20 | Christopher J Dannaker | Waterborne topical compositions for the delivery of active ingredients such as azelaic acid |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0109225B1 (en) * | 1982-11-11 | 1985-08-28 | Beecham Group Plc | Arachidonic acid analogues, processes for their preparation and their use in medicine |
| ES2052639T3 (es) * | 1987-06-26 | 1994-07-16 | Searle & Co | Analogos de fenilen-, furil- y tienil-leucotrieno b4. |
-
1989
- 1989-03-17 DE DE3909326A patent/DE3909326A1/de not_active Withdrawn
-
1990
- 1990-03-16 ES ES90904600T patent/ES2058896T3/es not_active Expired - Lifetime
- 1990-03-16 US US07/623,386 patent/US5183925A/en not_active Expired - Fee Related
- 1990-03-16 JP JP2504626A patent/JPH03505220A/ja active Pending
- 1990-03-16 EP EP90904600A patent/EP0416069B1/de not_active Expired - Lifetime
- 1990-03-16 AT AT90904600T patent/ATE92031T1/de not_active IP Right Cessation
- 1990-03-16 DK DK90904600.5T patent/DK0416069T3/da active
- 1990-03-16 DE DE9090904600T patent/DE59002088D1/de not_active Expired - Fee Related
- 1990-03-16 WO PCT/DE1990/000209 patent/WO1990011272A1/de not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| WO1990011272A1 (de) | 1990-10-04 |
| ES2058896T3 (es) | 1994-11-01 |
| US5183925A (en) | 1993-02-02 |
| DE59002088D1 (de) | 1993-09-02 |
| ATE92031T1 (de) | 1993-08-15 |
| EP0416069A1 (de) | 1991-03-13 |
| JPH03505220A (ja) | 1991-11-14 |
| DE3909326A1 (de) | 1990-09-20 |
| EP0416069B1 (de) | 1993-07-28 |
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