DK0417473T3 - Fremgangsmåde til behandling af cardial samt vaskulær hypertrofi og hyperplasi - Google Patents

Fremgangsmåde til behandling af cardial samt vaskulær hypertrofi og hyperplasi

Info

Publication number: DK0417473T3
Authority: DK; Denmark
Prior art keywords: treatment; hyperplasia; cardiac; administration; well
Prior art date: 1989-08-11

Application number

DK90115230.6T

Other languages

English (en)

Inventor

Wolfgang Dr Linz

Wolfgang Dr Scholz

Hansjoerg Dr Urbach

Bernward Prof Dr Schoelkens

Gabriele Dr Wiemer

Rainer Dr Henning

Volker Dr Teetz

Original Assignee

Hoechst Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-08-11

Filing date

1990-08-08

Publication date

1993-12-13

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6386970&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0417473(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1990-08-08 Application filed by Hoechst Ag filed Critical Hoechst Ag

1993-12-13 Application granted granted Critical

1993-12-13 Publication of DK0417473T3 publication Critical patent/DK0417473T3/da

Links

206010072810 Vascular wall hypertrophy Diseases 0.000 title abstract 2
230000000747 cardiac effect Effects 0.000 title abstract 2
206010020718 hyperplasia Diseases 0.000 title abstract 2
238000000034 method Methods 0.000 title abstract 2
206010007572 Cardiac hypertrophy Diseases 0.000 title 1
208000006029 Cardiomegaly Diseases 0.000 title 1
239000005541 ACE inhibitor Substances 0.000 abstract 2
229940044094 angiotensin-converting-enzyme inhibitor Drugs 0.000 abstract 2
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
239000003795 chemical substances by application Substances 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
201000010099 disease Diseases 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
125000000623 heterocyclic group Chemical group 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
- A61K38/556—Angiotensin converting enzyme inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Cardiology (AREA)
Vascular Medicine (AREA)
Gastroenterology & Hepatology (AREA)
Immunology (AREA)
Epidemiology (AREA)
Heart & Thoracic Surgery (AREA)
Urology & Nephrology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Crystals, And After-Treatments Of Crystals (AREA)
Medicinal Preparation (AREA)
Medicines Containing Plant Substances (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Preliminary Treatment Of Fibers (AREA)
Crucibles And Fluidized-Bed Furnaces (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Enzymes And Modification Thereof (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Element Separation (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

DK90115230.6T 1989-08-11 1990-08-08 Fremgangsmåde til behandling af cardial samt vaskulær hypertrofi og hyperplasi DK0417473T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE3926606A DE3926606A1 (de)	1989-08-11	1989-08-11	Verfahren zur behandlung der cardialen sowie der vasculaeren hypertrophie und hyperplasie

Publications (1)

Publication Number	Publication Date
DK0417473T3 true DK0417473T3 (da)	1993-12-13

Family

ID=6386970

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK90115230.6T DK0417473T3 (da)	1989-08-11	1990-08-08	Fremgangsmåde til behandling af cardial samt vaskulær hypertrofi og hyperplasi

Country Status (22)

Country	Link
US (1)	US5231083A (da)
EP (1)	EP0417473B1 (da)
JP (1)	JP3452199B2 (da)
KR (1)	KR0185969B1 (da)
AT (1)	ATE94409T1 (da)
AU (1)	AU631914B2 (da)
CA (1)	CA2023089C (da)
CS (1)	CS277644B6 (da)
DD (1)	DD297063A5 (da)
DE (2)	DE3926606A1 (da)
DK (1)	DK0417473T3 (da)
ES (1)	ES2059931T3 (da)
FI (1)	FI903936A7 (da)
HU (1)	HU205008B (da)
IE (1)	IE64604B1 (da)
IL (1)	IL95327A (da)
NO (1)	NO306979B1 (da)
NZ (1)	NZ234836A (da)
PH (1)	PH30831A (da)
PL (1)	PL286442A1 (da)
PT (1)	PT94957B (da)
ZA (1)	ZA906327B (da)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5643911A (en)	1994-05-19	1997-07-01	Mitsubishi Chemical Corporation	Medicament for therapeutic and prophylactic treatment of diseases caused by smooth muscle cell hyperplasia
SG68529A1 (en) *	1995-05-25	1999-11-16	Univ Singapore	The use of des-aspartate-angiotensin i (agr-val-tyr-ile-his-pro-phe-his-leu) as an anti-cardiac hypertrophic agent
SE9903028D0 (sv) *	1999-08-27	1999-08-27	Astra Ab	New use
DK1216038T3 (da) *	1999-08-30	2005-12-27	Sanofi Aventis Deutschland	Anvendelse af inhibitorer af reninangiotensinsystemet ved forebyggelsen af cardiovaskulære hændelser
US6395767B2 (en)	2000-03-10	2002-05-28	Bristol-Myers Squibb Company	Cyclopropyl-fused pyrrolidine-based inhibitors of dipeptidyl peptidase IV and method
RU2007120821A (ru) *	2004-11-05	2008-12-10	Кинг Фармасьютикалз Рисерч Энд Дивелопмент	Стабилизированные композиции рамиприла и способы получения
WO2012071369A2 (en)	2010-11-24	2012-05-31	The Trustees Of Columbia University In The City Of New York	A non-retinoid rbp4 antagonist for treatment of age-related macular degeneration and stargardt disease
US9333202B2 (en)	2012-05-01	2016-05-10	The Trustees Of Columbia University In The City Of New York	Non-retinoid antagonists for treatment of age-related macular degeneration and stargardt disease
US9938291B2 (en)	2013-03-14	2018-04-10	The Trustess Of Columbia University In The City Of New York	N-alkyl-2-phenoxyethanamines, their preparation and use
US10273243B2 (en)	2013-03-14	2019-04-30	The Trustees Of Columbia University In The City Of New York	4-phenylpiperidines, their preparation and use
US9944644B2 (en)	2013-03-14	2018-04-17	The Trustees Of Columbia University In The City Of New York	Octahydropyrrolopyrroles their preparation and use
EP2968303B1 (en) *	2013-03-14	2018-07-04	The Trustees of Columbia University in the City of New York	Octahydrocyclopentapyrroles, their preparation and use
CN111393434B (zh)	2014-04-30	2022-11-04	哥伦比亚大学董事会	取代的4-苯基哌啶及其制备和用途

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IL58849A (en) *	1978-12-11	1983-03-31	Merck & Co Inc	Carboxyalkyl dipeptides and derivatives thereof,their preparation and pharmaceutical compositions containing them
US4311705A (en) *	1980-10-06	1982-01-19	E. R. Squibb & Sons, Inc.	Carboxyalkanoyl and hydroxycarbamoylalkanoyl derivatives of substituted prolines
US4337201A (en) *	1980-12-04	1982-06-29	E. R. Squibb & Sons, Inc.	Phosphinylalkanoyl substituted prolines
US4381297A (en) *	1981-05-04	1983-04-26	E. R. Squibb & Sons, Inc.	Substituted carbonyl phosphinyl-alkanoyl compounds
US4602002A (en) *	1983-02-07	1986-07-22	Merck & Co., Inc.	N-carboxymethyl substituted lysyl and α-(ε-aminoalkyl) glycyl amino acid antihypertensive agents
US4587253A (en) *	1984-07-30	1986-05-06	Merck & Co., Inc.	Bridged pyridine compounds useful as calcium channel blockers and analgesics
US4548941A (en) *	1984-07-30	1985-10-22	Merck & Co., Inc.	1,5-Methano-1H-4-benzazonine dicarboxylates, process for preparing and use as calcium blockers
US4599341A (en) *	1984-10-01	1986-07-08	Merck & Co., Inc.	Substituted and bridged pyridines useful as calcium channel blockers
US4656188A (en) *	1985-10-09	1987-04-07	Merck & Co., Inc.	Ace inhibitors in macular degeneration
DE3705220A1 (de) *	1987-02-19	1988-09-01	Boehringer Ingelheim Kg	Mittel zur behandlung von coronarerkrankungen oder organischem hirnsyndrom
ZA896851B (en) *	1988-09-14	1990-06-27	Hoffmann La Roche	Use of ace-inhibitors

1989
- 1989-08-11 DE DE3926606A patent/DE3926606A1/de not_active Withdrawn
1990
- 1990-08-08 EP EP90115230A patent/EP0417473B1/de not_active Expired - Lifetime
- 1990-08-08 DK DK90115230.6T patent/DK0417473T3/da active
- 1990-08-08 AT AT90115230T patent/ATE94409T1/de not_active IP Right Cessation
- 1990-08-08 ES ES90115230T patent/ES2059931T3/es not_active Expired - Lifetime
- 1990-08-08 DE DE90115230T patent/DE59002721D1/de not_active Expired - Lifetime
- 1990-08-09 NZ NZ234836A patent/NZ234836A/en unknown
- 1990-08-09 DD DD90343366A patent/DD297063A5/de unknown
- 1990-08-09 PT PT94957A patent/PT94957B/pt not_active IP Right Cessation
- 1990-08-09 PH PH41000A patent/PH30831A/en unknown
- 1990-08-09 IL IL9532790A patent/IL95327A/en unknown
- 1990-08-09 FI FI903936A patent/FI903936A7/fi not_active Application Discontinuation
- 1990-08-09 US US07/564,618 patent/US5231083A/en not_active Expired - Lifetime
- 1990-08-10 KR KR1019900012267A patent/KR0185969B1/ko not_active Expired - Lifetime
- 1990-08-10 HU HU904966A patent/HU205008B/hu unknown
- 1990-08-10 JP JP21056490A patent/JP3452199B2/ja not_active Expired - Lifetime
- 1990-08-10 NO NO903532A patent/NO306979B1/no not_active IP Right Cessation
- 1990-08-10 IE IE291090A patent/IE64604B1/en not_active IP Right Cessation
- 1990-08-10 PL PL28644290A patent/PL286442A1/xx unknown
- 1990-08-10 AU AU60920/90A patent/AU631914B2/en not_active Expired
- 1990-08-10 CS CS903958A patent/CS277644B6/cs not_active IP Right Cessation
- 1990-08-10 ZA ZA906327A patent/ZA906327B/xx unknown
- 1990-08-10 CA CA002023089A patent/CA2023089C/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
PH30831A (en)	1997-10-17
IL95327A0 (en)	1991-06-30
KR0185969B1 (ko)	1999-05-01
CS395890A3 (en)	1992-08-12
ATE94409T1 (de)	1993-10-15
HU205008B (en)	1992-03-30
KR910004189A (ko)	1991-03-28
IE64604B1 (en)	1995-08-23
AU631914B2 (en)	1992-12-10
DE3926606A1 (de)	1991-02-14
EP0417473A1 (de)	1991-03-20
ZA906327B (en)	1991-05-29
IE902910A1 (en)	1991-02-27
NO903532L (no)	1991-02-12
NO306979B1 (no)	2000-01-24
HUT54504A (en)	1991-03-28
CA2023089C (en)	2003-01-14
JP3452199B2 (ja)	2003-09-29
JPH0383957A (ja)	1991-04-09
US5231083A (en)	1993-07-27
CA2023089A1 (en)	1991-02-12
IL95327A (en)	1995-10-31
CS277644B6 (en)	1993-03-17
PT94957B (pt)	1997-05-28
PT94957A (pt)	1991-05-22
PL286442A1 (en)	1992-03-09
ES2059931T3 (es)	1994-11-16
NO903532D0 (no)	1990-08-10
NZ234836A (en)	1997-05-26
FI903936A7 (fi)	1991-02-12
EP0417473B1 (de)	1993-09-15
DD297063A5 (de)	1992-01-02
HU904966D0 (en)	1991-01-28
DE59002721D1 (de)	1993-10-21
AU6092090A (en)	1991-02-14
FI903936A0 (fi)	1990-08-09

Publication	Publication Date	Title
AR002012A1 (es)	1998-01-07	Un compuesto, una composicion farmaceutica que lo comprende, su uso, metodo de tratamiento terapeutico, metodo para la preparacion del compuesto.
DK104292A (da)	1992-08-21	Heterocycliske forbindelser og fremgangsmaade til deres fremstilling
ES2074433T3 (es)	1995-09-16	Derivados de pirimidina, procedimiento para su produccion, y metodo herbicida y composicion.
ES2053609T3 (es)	1994-08-01	Derivados de urea inhibidores de lipoxigenasa.
DK490486A (da)	1987-04-16	Sammensaetning til behandling af atherosclerose, tromboser og/eller perifere karsygdomme
FI840463A0 (fi)	1984-02-06	Vissa bensazokinon- och bensazoninonderivat
FI903936A0 (fi)	1990-08-09	Saett att behandla hypertrofi och hyperplasi i hjaerta och blodkaerl.
DK495683A (da)	1984-04-30	Beta-carboliner, fremgangsmaade til fremstilling af samme og farmaceutisk praeparat indeholdende samme
DK33196A (da)	1996-03-21	Anvendelse af disubstituerede prolinderivater til fremstilling af tilsvarende carboxylsyrer og deres derivater
BG96171A (bg)	1993-12-24	Амидинофенилаланинови производни,метод за получаването им, приложението им и средства,които ги съдържат
NO952205L (no)	1995-06-02	Heterocykliske karbamater, fremgangsmåte for fremstilling derav og medikamenter
DK282285D0 (da)	1985-06-21	Hidtil ukendte 8-alkylthio-2-piperazino-pyrimido(5,4-d)pyrimidiner,deres fremstilling og laegemidler indeholdende disse forbindelser
DK165247C (da)	1993-04-26	2,3,4,5-substituerede 1,6-naphthyridinderivater, deres fremstilling samt anvendelse af disse til fremstilling af laegemidler til bekaempelse af cardiale, cerebrale og perifere karlidelser, myocardial iskaemi, cerebral infarkt, lungethrombose, stenoser, arterioscleroser og hjerte-kredsloebslidelser og laegemiddel indeholdende disse derivater
DK0736009T3 (da)	2002-10-07	N-oxider af 4-arylpiperaziner og 4-arylpiperidiner som antipsykotiske medikamenter
DK440987D0 (da)	1987-08-24	Thyroninderivater, deres fremstilling og anvendelse
EA199900684A1 (ru)	2000-04-24	Производные иминоазаантрациклинона для лечения амилоидоза
ES2147316T3 (es)	2000-09-01	1-cicloalqueniltetrazolinonas.
CO4770971A1 (es)	1999-04-30	Compuestos quimicos
FI944967L (fi)	1994-10-21	Menetelmiä proteolyyttisen entsyymin inhibiittoreina käyttökelpoisten sakkariinijohdannaisten ja niiden välituotteiden valmistamiseksi
DK572189A (da)	1989-11-15	Substituerede adeninderivater og farmaceutisk praeparat indeholdende dem