DK0419099T3 - Proteiner med antikoagulationsegenskaber - Google Patents

Proteiner med antikoagulationsegenskaber

Info

Publication number: DK0419099T3
Authority: DK; Denmark
Prior art keywords: proteins; inhibitors; factor; anticoagulant properties; inhibit
Prior art date: 1989-09-07

Application number

DK90309834.1T

Other languages

Danish (da)

English (en)

Inventor

George P Vlasuk

Lloyd H Waxman

Victor M Garsky

Michael P Neeper

Original Assignee

Merck & Co Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-09-07

Filing date

1990-09-07

Publication date

1996-03-11

1990-09-07 Application filed by Merck & Co Inc filed Critical Merck & Co Inc

1996-03-11 Application granted granted Critical

1996-03-11 Publication of DK0419099T3 publication Critical patent/DK0419099T3/da

Links

102000004169 proteins and genes Human genes 0.000 title abstract 2
108090000623 proteins and genes Proteins 0.000 title abstract 2
230000002429 anti-coagulating effect Effects 0.000 title 1
239000003112 inhibitor Substances 0.000 abstract 2
108090000317 Chymotrypsin Proteins 0.000 abstract 1
108010054265 Factor VIIa Proteins 0.000 abstract 1
108010080805 Factor XIa Proteins 0.000 abstract 1
108010074860 Factor Xa Proteins 0.000 abstract 1
108010088842 Fibrinolysin Proteins 0.000 abstract 1
108010051815 Glutamyl endopeptidase Proteins 0.000 abstract 1
108060005987 Kallikrein Proteins 0.000 abstract 1
102000001399 Kallikrein Human genes 0.000 abstract 1
241000238890 Ornithodoros moubata Species 0.000 abstract 1
108010067372 Pancreatic elastase Proteins 0.000 abstract 1
102000016387 Pancreatic elastase Human genes 0.000 abstract 1
108020004511 Recombinant DNA Proteins 0.000 abstract 1
240000004808 Saccharomyces cerevisiae Species 0.000 abstract 1
108090000190 Thrombin Proteins 0.000 abstract 1
102000003978 Tissue Plasminogen Activator Human genes 0.000 abstract 1
108090000373 Tissue Plasminogen Activator Proteins 0.000 abstract 1
108090000631 Trypsin Proteins 0.000 abstract 1
102000004142 Trypsin Human genes 0.000 abstract 1
102000003990 Urokinase-type plasminogen activator Human genes 0.000 abstract 1
108090000435 Urokinase-type plasminogen activator Proteins 0.000 abstract 1
125000000539 amino acid group Chemical group 0.000 abstract 1
229960002376 chymotrypsin Drugs 0.000 abstract 1
229940012414 factor viia Drugs 0.000 abstract 1
229940012957 plasmin Drugs 0.000 abstract 1
229920001184 polypeptide Polymers 0.000 abstract 1
102000004196 processed proteins & peptides Human genes 0.000 abstract 1
108090000765 processed proteins & peptides Proteins 0.000 abstract 1
229960004072 thrombin Drugs 0.000 abstract 1
229960000187 tissue plasminogen activator Drugs 0.000 abstract 1
239000012588 trypsin Substances 0.000 abstract 1
229960001322 trypsin Drugs 0.000 abstract 1
229960005356 urokinase Drugs 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/81—Protease inhibitors
- C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
- C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Diabetes (AREA)
Hematology (AREA)
Chemical Kinetics & Catalysis (AREA)
Gastroenterology & Hepatology (AREA)
Biochemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)

DK90309834.1T 1989-09-07 1990-09-07 Proteiner med antikoagulationsegenskaber DK0419099T3 (da)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date
US40403389A	1989-09-07	1989-09-07
US49830790A	1990-03-23	1990-03-23
US56516490A	1990-08-13	1990-08-13

Publications (1)

Publication Number	Publication Date
DK0419099T3 true DK0419099T3 (da)	1996-03-11

Family

ID=27410566

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK90309834.1T DK0419099T3 (da)	1989-09-07	1990-09-07	Proteiner med antikoagulationsegenskaber

Country Status (8)

Country	Link
EP (1)	EP0419099B1 (de)
JP (1)	JP3034926B2 (de)
AT (1)	ATE133962T1 (de)
AU (1)	AU639257B2 (de)
CA (1)	CA2024697A1 (de)
DE (1)	DE69025247T2 (de)
DK (1)	DK0419099T3 (de)
IE (1)	IE70759B1 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3819078A1 (de) *	1988-06-04	1989-12-07	Hoechst Ag	Amblyommin, ein neuer wirkstoff fuer die antikoagulationstherapie
US5278144A (en) *	1990-09-04	1994-01-11	Cor Therapeutics, Inc.	Antithrombosis agents
DE4136087A1 (de) *	1991-10-31	1993-05-06	Basf Ag, 6700 Ludwigshafen, De	Neues thrombininhibitorisches protein aus zecken
US5321010A (en) *	1991-12-10	1994-06-14	Merck & Co., Inc.	Proteins for inhibiting adhesion of platelets to collagen
WO1994012204A1 (en) *	1992-12-01	1994-06-09	Merck & Co., Inc.	Anticoagulant proteins
AU7868394A (en) *	1993-10-29	1995-05-22	Merck & Co., Inc.	Antithrombotic proteins
US5872098A (en) *	1995-06-05	1999-02-16	Corvas International, Inc.	Nematode-extracted anticoagulant protein
US5866542A (en) *	1994-10-18	1999-02-02	Corvas International, Inc.	Nematode-extracted anticoagulant protein
US5945275A (en) *	1994-10-18	1999-08-31	Corvas International, Inc.	Nematode-extracted anticoagulant protein
US6090916A (en) *	1994-10-18	2000-07-18	Corvas International, Inc.	Nematode-extracted serine protease inhibitors and anticoagulant proteins
CA2202351A1 (en) *	1994-10-18	1996-04-25	George Phillip Vlasuk	Nematode-extracted serine protease inhibitors and anticoagulant proteins
US5866543A (en) *	1995-06-05	1999-02-02	Corvas International, Inc.	Nematode-extracted anticoagulant protein
US5863894A (en) *	1995-06-05	1999-01-26	Corvas International, Inc.	Nematode-extracted anticoagulant protein
SA96170106A (ar) *	1995-07-06	2005-12-03	أسترا أكتيبولاج	مشتقات حامض أميني جديدة
US6245741B1 (en)	1998-05-19	2001-06-12	Washington University	Protein Z-dependent protease inhibitor
EP1569912B1 (de)	2002-12-03	2015-04-29	Pharmacyclics, Inc.	2-(2-hydroxybiphenyl-3-yl)-1h-benzoimidazole-5-carboxamidinderivate als faktor vii-a hemmer
CA2623565A1 (en)	2005-09-28	2007-04-05	Biovascular, Inc.	Methods and compositions for blocking platelet and cell adhesion, cell migration and inflammation
CN112552382A (zh) *	2020-01-22	2021-03-26	天津科技大学	一种信号肽突变体及其用途

1990
- 1990-09-05 CA CA002024697A patent/CA2024697A1/en not_active Abandoned
- 1990-09-06 IE IE324590A patent/IE70759B1/en not_active IP Right Cessation
- 1990-09-06 AU AU62247/90A patent/AU639257B2/en not_active Ceased
- 1990-09-07 DE DE69025247T patent/DE69025247T2/de not_active Expired - Fee Related
- 1990-09-07 AT AT90309834T patent/ATE133962T1/de not_active IP Right Cessation
- 1990-09-07 DK DK90309834.1T patent/DK0419099T3/da active
- 1990-09-07 JP JP2235994A patent/JP3034926B2/ja not_active Expired - Fee Related
- 1990-09-07 EP EP90309834A patent/EP0419099B1/de not_active Expired - Lifetime

Also Published As

Publication number	Publication date
IE903245A1 (en)	1991-03-13
AU639257B2 (en)	1993-07-22
DE69025247T2 (de)	1996-09-12
ATE133962T1 (de)	1996-02-15
CA2024697A1 (en)	1991-03-08
IE70759B1 (en)	1996-12-30
JPH03178997A (ja)	1991-08-02
AU6224790A (en)	1991-03-14
JP3034926B2 (ja)	2000-04-17
DE69025247D1 (de)	1996-03-21
EP0419099A1 (de)	1991-03-27
EP0419099B1 (de)	1996-02-07

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