DK0421829T3 - Nye benzopyranon-beta-D-thioxylosider, fremgangsmåde til deres fremstilling og deres terapeutiske anvendelse - Google Patents

Nye benzopyranon-beta-D-thioxylosider, fremgangsmåde til deres fremstilling og deres terapeutiske anvendelse

Info

Publication number
DK0421829T3
DK0421829T3 DK90402403.1T DK90402403T DK0421829T3 DK 0421829 T3 DK0421829 T3 DK 0421829T3 DK 90402403 T DK90402403 T DK 90402403T DK 0421829 T3 DK0421829 T3 DK 0421829T3
Authority
DK
Denmark
Prior art keywords
group
benzopyranone
beta
atom
thioxylosides
Prior art date
Application number
DK90402403.1T
Other languages
English (en)
Inventor
Soth Samreth
Veronique Barberousse
Patrice Renaut
Francois Bellamy
Jean Millet
Original Assignee
Fournier Ind & Sante
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR8912452A external-priority patent/FR2652353B1/fr
Priority claimed from FR9003401A external-priority patent/FR2659659B1/fr
Application filed by Fournier Ind & Sante filed Critical Fournier Ind & Sante
Application granted granted Critical
Publication of DK0421829T3 publication Critical patent/DK0421829T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
    • C07D311/08—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
    • C07D311/12—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted in position 3 and unsubstituted in position 7
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
    • C07D311/08—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
    • C07D311/14—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted in position 6 and unsubstituted in position 7
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
    • C07D311/08—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
    • C07D311/16—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted in position 7
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
    • C07D311/08—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
    • C07D311/18—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted otherwise than in position 3 or 7
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/06—Benzopyran radicals
    • C07H17/065—Benzo[b]pyrans
    • C07H17/07—Benzo[b]pyran-4-ones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/06—Benzopyran radicals
    • C07H17/065—Benzo[b]pyrans
    • C07H17/075—Benzo[b]pyran-2-ones

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pyrane Compounds (AREA)
  • Dental Preparations (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Cultivation Of Plants (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
DK90402403.1T 1989-09-22 1990-08-31 Nye benzopyranon-beta-D-thioxylosider, fremgangsmåde til deres fremstilling og deres terapeutiske anvendelse DK0421829T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8912452A FR2652353B1 (fr) 1989-09-22 1989-09-22 Nouveaux benzopyran-2-one-beta-d-thioxylosides, leur procede de preparation et leur utilisation en therapeutique.
FR9003401A FR2659659B1 (fr) 1990-03-16 1990-03-16 Nouveaux benzopyran-4-one-beta-d-thioxylosides, leur procede de preparation et leur utilisation en therapeutique.

Publications (1)

Publication Number Publication Date
DK0421829T3 true DK0421829T3 (da) 1995-01-16

Family

ID=26227568

Family Applications (1)

Application Number Title Priority Date Filing Date
DK90402403.1T DK0421829T3 (da) 1989-09-22 1990-08-31 Nye benzopyranon-beta-D-thioxylosider, fremgangsmåde til deres fremstilling og deres terapeutiske anvendelse

Country Status (24)

Country Link
US (1) US5169838A (da)
EP (1) EP0421829B1 (da)
JP (1) JPH07103147B2 (da)
KR (1) KR0142670B1 (da)
CN (1) CN1027268C (da)
AT (1) ATE113956T1 (da)
AU (2) AU631456B2 (da)
CA (1) CA2024476C (da)
DE (1) DE69014064T2 (da)
DK (1) DK0421829T3 (da)
ES (1) ES2066165T3 (da)
FI (1) FI100183B (da)
GR (1) GR3014966T3 (da)
HR (1) HRP920811B1 (da)
HU (1) HU207867B (da)
IE (1) IE65092B1 (da)
IL (1) IL95582A (da)
NO (1) NO172987C (da)
NZ (1) NZ245783A (da)
PT (1) PT95369B (da)
RU (1) RU1838323C (da)
SK (1) SK463890A3 (da)
UA (1) UA13476A (da)
YU (1) YU47867B (da)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2801055B1 (fr) * 1999-11-17 2002-02-08 Fournier Ind & Sante Derives de beta-d-5-thioxylose, procede de preparation et utilisation en therapeutique
FR2824559B1 (fr) * 2001-05-11 2004-02-13 Fournier Lab Sa Nouveaux derives 5-thio-beta-xylopyronasides, procede de preparation, compositions pharmaceutiques les contenant et leur utilisation en therapeutique
FR2846966A1 (fr) * 2002-11-07 2004-05-14 Fournier Lab Sa Derive du 4-methyl-2-oxo-2h-1-benzopyran-7-yl 5-thio-beta-d- xylopyranoside, son procede de preparation et composition pharmaceutique le contenant
CN1802372B (zh) * 2003-06-11 2010-05-12 麦克弗罗斯特加拿大有限公司 7＇-(1,3-噻唑-2-基)-硫代香豆素及其作为白三烯生物合成抑制剂的应用
FR2860234B1 (fr) 2003-09-25 2005-12-23 Fournier Lab Sa Nouveaux derives 666 du thioxylose
TW200640449A (en) * 2005-02-18 2006-12-01 Smithkline Beecham Corp Pharmaceutical compositions and methods
FR2903698B1 (fr) 2006-07-13 2009-01-30 Fournier S A Sa Lab Nouveaux derives de 5-thioxylopyranose.
FR2906247B1 (fr) 2006-09-27 2008-12-26 Fournier S A Sa Lab Nouveaux derives de 5-thioxylopyranose
FR2906248B1 (fr) 2006-09-27 2008-12-26 Fournier S A Sa Lab Nouveaux derives de 5-thioxylopyranose
US20090075914A1 (en) * 2007-09-13 2009-03-19 Protia, Llc Deuterium-enriched odiparcil
CN101397315B (zh) * 2007-09-24 2013-08-07 中国医学科学院药物研究所 香豆素苷类化合物、其制法和其药物组合物与用途
US10092540B2 (en) 2013-10-04 2018-10-09 Inventiva Method of treatment of a mucopolysaccharidosis
FR3011468B1 (fr) 2013-10-04 2015-12-04 Inventiva Utilisation de l'odiparcil dans le traitement d'une mucopolysaccharidose

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2034306A1 (de) * 1970-07-10 1972-01-20 Boehnnger Mannheim GmbH, 6800 Mann heim Waldhof 2 (3,4 Dimethyl-cumarin 7 yl) oxy alkylcarbonsaure Derivate und Verfahren zu ihrer Herstellung
FR2492830A1 (fr) * 1980-10-29 1982-04-30 Sori Soc Rech Ind Nouveaux composes appartenant a la famille des benzoyl- et a-hydroxybenzyl-phenyl-osides, leur procede de preparation et leur application en therapeutique
JPS6013788A (ja) * 1983-07-05 1985-01-24 Yamanouchi Pharmaceut Co Ltd 新規なクマリン誘導体
FR2549476B1 (fr) * 1983-07-20 1986-04-25 Rech Ind Benzyl-phenyl-osides, procede de preparation et utilisation en therapeutique
US4681954A (en) * 1985-10-07 1987-07-21 Pennwalt Corporation 7,8,9,10-tetrahydro-6-oxo-6H-dibenzo(b,d)pyranyloxy-propanes
FR2614893B1 (fr) * 1987-05-04 1989-12-22 Fournier Innovation Synergie Nouveaux b-d-phenyl-thioxylosides, leur procede de preparation et leur application en therapeutique

Also Published As

Publication number Publication date
IL95582A (en) 2001-06-14
JPH03120292A (ja) 1991-05-22
IL95582A0 (en) 1991-06-30
HU207867B (en) 1993-06-28
NO172987B (no) 1993-06-28
DE69014064D1 (de) 1994-12-15
NO172987C (no) 1993-10-06
EP0421829A1 (fr) 1991-04-10
AU2539792A (en) 1992-11-26
JPH07103147B2 (ja) 1995-11-08
ES2066165T3 (es) 1995-03-01
AU6253190A (en) 1991-03-28
AU631456B2 (en) 1992-11-26
KR910006283A (ko) 1991-04-29
RU1838323C (ru) 1993-08-30
CA2024476A1 (en) 1991-03-23
HUT55794A (en) 1991-06-28
SK280827B6 (sk) 2000-08-14
NZ245783A (en) 1993-07-27
NO904088D0 (no) 1990-09-19
PT95369A (pt) 1991-05-22
AU642829B2 (en) 1993-10-28
DE69014064T2 (de) 1995-05-18
YU47867B (sh) 1996-02-19
CA2024476C (en) 1999-10-12
CN1050544A (zh) 1991-04-10
SK463890A3 (en) 2000-08-14
IE903414A1 (en) 1991-04-10
CN1027268C (zh) 1995-01-04
KR0142670B1 (ko) 1998-07-01
GR3014966T3 (en) 1995-05-31
ATE113956T1 (de) 1994-11-15
IE65092B1 (en) 1995-10-04
HRP920811B1 (en) 1998-12-31
NO904088L (no) 1991-03-25
UA13476A (uk) 1997-04-25
PT95369B (pt) 1997-06-30
US5169838A (en) 1992-12-08
YU178790A (sh) 1992-12-21
FI904614A0 (fi) 1990-09-19
FI100183B (fi) 1997-10-15
HU906005D0 (en) 1991-03-28
HRP920811A2 (en) 1995-10-31
EP0421829B1 (fr) 1994-11-09

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