DK0422154T3 - Terapeutisk anvendelse af 5-HT3-receptorantagonister - Google Patents

Terapeutisk anvendelse af 5-HT3-receptorantagonister

Info

Publication number: DK0422154T3
Authority: DK; Denmark
Prior art keywords: receptor antagonists; therapeutic use; disorders; agoraphobia; useful
Prior art date: 1989-04-21

Application number

DK90905482.7T

Other languages

English (en)

Inventor

Alberto Azcona

Original Assignee

Sandoz Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-04-21

Filing date

1990-04-06

Publication date

1994-03-07

1989-04-21 Priority claimed from GB898909147A external-priority patent/GB8909147D0/en

1989-07-20 Priority claimed from GB898916602A external-priority patent/GB8916602D0/en

1990-04-06 Application filed by Sandoz Ag filed Critical Sandoz Ag

1994-03-07 Application granted granted Critical

1994-03-07 Publication of DK0422154T3 publication Critical patent/DK0422154T3/da

Links

102000035037 5-HT3 receptors Human genes 0.000 title abstract 2
108091005477 5-HT3 receptors Proteins 0.000 title abstract 2
239000002464 receptor antagonist Substances 0.000 title abstract 2
229940044551 receptor antagonist Drugs 0.000 title abstract 2
230000001225 therapeutic effect Effects 0.000 title 1
208000008811 Agoraphobia Diseases 0.000 abstract 1
208000021384 Obsessive-Compulsive disease Diseases 0.000 abstract 1
208000019906 panic disease Diseases 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Bioinformatics & Cheminformatics (AREA)
General Chemical & Material Sciences (AREA)
Emergency Medicine (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Anesthesiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Plural Heterocyclic Compounds (AREA)

DK90905482.7T 1989-04-21 1990-04-06 Terapeutisk anvendelse af 5-HT3-receptorantagonister DK0422154T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB898909147A GB8909147D0 (en)	1989-04-21	1989-04-21	Improvements in or relating to organic compounds
GB898916602A GB8916602D0 (en)	1989-07-20	1989-07-20	Improvements in or relating to organic compounds

Publications (1)

Publication Number	Publication Date
DK0422154T3 true DK0422154T3 (da)	1994-03-07

Family

ID=26295258

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK90905482.7T DK0422154T3 (da)	1989-04-21	1990-04-06	Terapeutisk anvendelse af 5-HT3-receptorantagonister

Country Status (10)

Country	Link
EP (1)	EP0422154B1 (da)
JP (1)	JPH0669963B2 (da)
KR (1)	KR920700034A (da)
AT (1)	ATE97803T1 (da)
AU (1)	AU631632B2 (da)
CA (1)	CA2031214A1 (da)
DE (1)	DE69004924T2 (da)
DK (1)	DK0422154T3 (da)
ES (1)	ES2061024T3 (da)
WO (1)	WO1990012569A1 (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5276050A (en) *	1989-08-01	1994-01-04	Glaxo Group Limited	Medicaments
US5225407A (en) *	1990-02-22	1993-07-06	Glaxo Group Limited	5-HT3 receptor antagonists for the treatment of autism
US5508287A (en) *	1992-02-24	1996-04-16	Merrell Pharmaceuticals Inc.	2,6-methano-2H-quinolizin derivative as 5-HT3 -receptor antagonist
US5763459A (en) *	1992-05-23	1998-06-09	Smithkline Beecham P.L.C.	Medicaments for the treatment of anxiety
US7601856B2 (en)	2006-07-27	2009-10-13	Wyeth	Benzofurans as potassium ion channel modulators
US8563567B2 (en)	2009-12-30	2013-10-22	Arqule, Inc.	Substituted heterocyclic compounds
US20110288115A1 (en) *	2010-05-24	2011-11-24	Avmedis Llc	Treatment of vagally-mediated spectrum disorders
JP5387648B2 (ja)	2011-10-14	2014-01-15	株式会社デンソー	指針表示装置

Family Cites Families (36)

* Cited by examiner, † Cited by third party
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GB1365296A (en) *	1970-10-30	1974-08-29	Unilever Ltd	Dentifrice compositions
EP0099194A3 (en) *	1982-07-03	1984-04-11	Beecham Group Plc	Novel benzamides
PH22672A (en) *	1984-01-25	1988-11-14	Glaxo Group Ltd	Imidazolylmethyltetrahydrocarbazolone derivatives, composition and method of use thereof
AU583343B2 (en)	1985-01-23	1989-04-27	Glaxo Group Limited	Heterocyclic compounds
EP0385517B1 (en) *	1985-03-14	1993-04-14	BEECHAM GROUP plc	Medicaments for the treatment of emesis
GB8518658D0 (en) *	1985-07-24	1985-08-29	Glaxo Group Ltd	Medicaments
GB8518741D0 (en)	1985-07-24	1985-08-29	Glaxo Group Ltd	Process
GB8518743D0 (en)	1985-07-24	1985-08-29	Glaxo Group Ltd	Heterocyclic compounds
GB8518745D0 (en)	1985-07-24	1985-08-29	Glaxo Group Ltd	Heterocyclic compounds
EP0212398A2 (de)	1985-08-21	1987-03-04	Siemens Aktiengesellschaft	Verfahren zur Erkennung von Mehrfrequenzcodesignalen mit überlagerten Störsignalen
IL80707A (en)	1985-12-23	1991-03-10	Hughes Aircraft Co	Gaseous discharge device simmering circuit
EP0242973B1 (en)	1986-03-17	1991-07-17	Glaxo Group Limited	Indole derivatives, method for their preparation and pharmaceutical compositions containing them
GB8701494D0 (en)	1987-01-23	1987-02-25	Glaxo Group Ltd	Chemical compounds
GB8617994D0 (en)	1986-07-23	1986-08-28	Glaxo Group Ltd	Heterocyclic compounds
EP0254584B1 (en) *	1986-07-25	1992-10-07	Beecham Group Plc	Azabicyclic compounds, process for their preparation, and their pharmaceutical use
HU202108B (en)	1986-07-30	1991-02-28	Sandoz Ag	Process for producing pharmaceutical compositions containing serotonine antqgonistic derivatives of indol-carboxylic acid or imidazolyl-methyl-carbazol
GB8623819D0 (en)	1986-10-03	1986-11-05	Glaxo Group Ltd	Heterocyclic compounds
EP0279114B2 (en)	1986-11-21	1995-08-23	Glaxo Group Limited	Medicaments for the treatment or prevention of the withdrawal syndrome
GR871809B (en)	1986-11-28	1988-03-07	Glaxo Group Ltd	Process for the preparation of tricyclic ketones
ES2051753T3 (es) *	1986-12-16	1994-07-01	Robins Co Inc A H	N-(1-azabiciclo(2.2.2)octo-3-il) benzamidas y tiobenzamidas ansioliticas.
GB8806990D0 (en)	1988-03-23	1988-04-27	Beecham Group Plc	Novel compounds
US4918080A (en)	1987-04-14	1990-04-17	Glaxo Group Limited	Imidazollyl containing ketone derivatives
DE3827253A1 (de)	1987-08-20	1989-03-02	Sandoz Ag	Ester und amide von cyclischen carbonsaeuren und cyclischen alkoholen und aminen sowie verfahren zu deren herstellung und sie enthaltende therapeutische zusammensetzungen
NZ226032A (en)	1987-09-03	1991-12-23	Glaxo Group Ltd	2-(imidazolylmethyl)-pyrido or-azepino(4,3-b)indole-1(2h)-one derivatives; preparatory processes and pharmaceutical compositions
GB8720693D0 (en)	1987-09-03	1987-10-07	Glaxo Group Ltd	Chemical compounds
GB8720805D0 (en) *	1987-09-04	1987-10-14	Naylor R J	2-alkoxy-n-(1-azabicyclo(2 2 2)oct-3-yl)benzamides & thiobenzamides
EP0317088A1 (en)	1987-10-22	1989-05-24	Glaxo Group Limited	Ketone derivatives
DE3740984A1 (de) *	1987-12-03	1989-06-15	Sandoz Ag	N-oxide von heterocyclischen carbonsaeurederivaten bzw. verfahren zu deren herstellung und deren verwendung
GB8802127D0 (en)	1988-02-01	1988-03-02	Glaxo Group Ltd	Chemical compounds
EP0329904A1 (en) *	1988-02-23	1989-08-30	Merrell Dow Pharmaceuticals Inc.	Use of quinolizine and quinolizinone derivatives in the manufacture of medicaments for the treatment of anxiety
EP0329932B1 (en) *	1988-02-23	1995-10-18	Merrell Pharmaceuticals Inc.	Use of quinolizine and quinolizinone derivatives in the manufacture of medicaments
US5116984A (en)	1988-04-07	1992-05-26	Glaxo Group Limited	Imidazole derivatives
EP0339959A3 (en)	1988-04-27	1991-03-20	Glaxo Group Limited	Lactam derivatives
US4863921A (en)	1988-04-27	1989-09-05	Rorer Pharmaceutical Corporation	Dibenzofurancarboxamides and their pharmaceutical compositions and methods
GB8812636D0 (en)	1988-05-27	1988-06-29	Glaxo Group Ltd	Chemical compounds
GB8814277D0 (en)	1988-06-16	1988-07-20	Glaxo Group Ltd	Chemical compounds

1990
- 1990-04-06 JP JP2505770A patent/JPH0669963B2/ja not_active Expired - Lifetime
- 1990-04-06 AT AT90905482T patent/ATE97803T1/de not_active IP Right Cessation
- 1990-04-06 AU AU54158/90A patent/AU631632B2/en not_active Ceased
- 1990-04-06 ES ES90905482T patent/ES2061024T3/es not_active Expired - Lifetime
- 1990-04-06 DE DE69004924T patent/DE69004924T2/de not_active Expired - Fee Related
- 1990-04-06 EP EP90905482A patent/EP0422154B1/en not_active Expired - Lifetime
- 1990-04-06 CA CA002031214A patent/CA2031214A1/en not_active Abandoned
- 1990-04-06 WO PCT/EP1990/000540 patent/WO1990012569A1/en not_active Ceased
- 1990-04-06 KR KR1019900702651A patent/KR920700034A/ko not_active Ceased
- 1990-04-06 DK DK90905482.7T patent/DK0422154T3/da active

Also Published As

Publication number	Publication date
EP0422154A1 (en)	1991-04-17
AU5415890A (en)	1990-11-16
JPH03505881A (ja)	1991-12-19
KR920700034A (ko)	1992-02-19
WO1990012569A1 (en)	1990-11-01
DE69004924T2 (de)	1994-05-19
AU631632B2 (en)	1992-12-03
JPH0669963B2 (ja)	1994-09-07
CA2031214A1 (en)	1990-10-22
ES2061024T3 (es)	1994-12-01
EP0422154B1 (en)	1993-12-01
ATE97803T1 (de)	1993-12-15
DE69004924D1 (de)	1994-01-13

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