DK0435153T3 - R-(-)-1-(5-Hydroxyhexyl)-3-methyl-7-propylxanthin, fremgangsmåde til dens fremstilling og lægemidler med indhold deraf - Google Patents

R-(-)-1-(5-Hydroxyhexyl)-3-methyl-7-propylxanthin, fremgangsmåde til dens fremstilling og lægemidler med indhold deraf

Info

Publication number: DK0435153T3
Authority: DK; Denmark
Prior art keywords: propylxanthine; hydroxyhexyl; methyl; preparation; drugs containing
Prior art date: 1989-12-23

Application number

DK90124747.8T

Other languages

English (en)

Inventor

Harald Dr Furrer

Ulrich Dr Gebert

Karl Dr Rudolphi

Original Assignee

Hoechst Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-12-23

Filing date

1990-12-19

Publication date

1996-08-05

1990-12-19 Application filed by Hoechst Ag filed Critical Hoechst Ag

1996-08-05 Application granted granted Critical

1996-08-05 Publication of DK0435153T3 publication Critical patent/DK0435153T3/da

Links

CERFGCPAKWKZEK-LLVKDONJSA-N 1-[(5r)-5-hydroxyhexyl]-3-methyl-7-propylpurine-2,6-dione Chemical compound CN1C(=O)N(CCCC[C@@H](C)O)C(=O)C2=C1N=CN2CCC CERFGCPAKWKZEK-LLVKDONJSA-N 0.000 title abstract 2
229940079593 drug Drugs 0.000 title abstract 2
239000003814 drug Substances 0.000 title abstract 2
238000000034 method Methods 0.000 title abstract 2
230000002490 cerebral effect Effects 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
201000010099 disease Diseases 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
238000011321 prophylaxis Methods 0.000 abstract 1
238000002560 therapeutic procedure Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
- C12P17/182—Heterocyclic compounds containing nitrogen atoms as the only ring heteroatoms in the condensed system

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
General Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
General Chemical & Material Sciences (AREA)
Genetics & Genomics (AREA)
Biotechnology (AREA)
General Engineering & Computer Science (AREA)
Biochemistry (AREA)
Microbiology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Cardiology (AREA)
Pharmacology & Pharmacy (AREA)
Heart & Thoracic Surgery (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Steroid Compounds (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

DK90124747.8T 1989-12-23 1990-12-19 R-(-)-1-(5-Hydroxyhexyl)-3-methyl-7-propylxanthin, fremgangsmåde til dens fremstilling og lægemidler med indhold deraf DK0435153T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE3942871A DE3942871A1 (de)	1989-12-23	1989-12-23	R-(-)-1-(5-hydroxyhexyl)-3-methyl-7-propylxanthin, verfahren zu dessen herstellung und diese verbindung enthaltende arzneimittel

Publications (1)

Publication Number	Publication Date
DK0435153T3 true DK0435153T3 (da)	1996-08-05

Family

ID=6396380

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK90124747.8T DK0435153T3 (da)	1989-12-23	1990-12-19	R-(-)-1-(5-Hydroxyhexyl)-3-methyl-7-propylxanthin, fremgangsmåde til dens fremstilling og lægemidler med indhold deraf

Country Status (9)

Country	Link
US (2)	US5407815A (da)
EP (1)	EP0435153B1 (da)
JP (1)	JPH07107063B2 (da)
KR (1)	KR0179654B1 (da)
AT (1)	ATE137237T1 (da)
DE (2)	DE3942871A1 (da)
DK (1)	DK0435153T3 (da)
ES (1)	ES2086359T3 (da)
GR (1)	GR3019860T3 (da)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
TW209834B (da) *	1991-12-11	1993-07-21	Hoechst Ag
US5567704A (en) *	1992-03-04	1996-10-22	Cell Therapeutics, Inc.	R-enatiomerically pure hydroxylated xanthine compounds to treat baldness
US5648357A (en) *	1992-03-04	1997-07-15	Cell Therapeutics, Inc.	Enatiomerically pure hydroxylated xanthine compounds
CA2112239C (en) *	1992-03-04	2000-05-09	James A. Bianco	Enantiomeric hydroxylated xanthine compounds
US5780476A (en) *	1992-11-16	1998-07-14	Cell Therapeutics, Inc.	Hydroxyl-containing xanthine compounds
DK0677105T3 (da) *	1992-12-31	2006-07-10	Immulogic Pharma Corp	Allergifremkaldende proteiner og peptider fra hundeskæl og anvendelser derfor
WO1994016704A1 (en) *	1993-01-19	1994-08-04	Cell Therapeutics, Inc.	Oxime-substituted therapeutic compounds
US5620676A (en) *	1994-03-08	1997-04-15	The United States Of America As Represented By The Department Of Health And Human Services	Biologically active ATP analogs
WO2012031072A1 (en) *	2010-09-01	2012-03-08	Concert Pharmaceuticals, Inc.	Process for preparing an enantiomerically enriched, deuterated secondary alcohol from a corresponding ketone without reducing deuterium incorporation
US9074233B2 (en)	2010-09-01	2015-07-07	Concert Pharmaceuticals, Inc.	Process for preparing an enantiomerically enriched, deuterated secondary alcohol from a corresponding ketone without reducing deuterium incorporation

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4576947A (en) *	1967-12-16	1986-03-18	Hoechst Aktiengesellschaft	Pharmaceutical compositions
DE2335170C2 (de) *	1973-07-11	1989-07-20	Hoechst Ag, 6230 Frankfurt	1,3-Dialkyl-7-(hydroxyalkyl)-xanthine, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel
US4515795A (en) *	1968-11-25	1985-05-07	Hoechst Aktiengesellschaft	Pharmaceutical compositions
DE2366527C2 (da) *	1973-07-11	1987-08-27	Hoechst Ag, 6230 Frankfurt, De
US4517795A (en) *	1979-11-28	1985-05-21	Deere & Company	Bale-shape gauge for baler for forming cylindrical bales
US4857468A (en) *	1985-04-13	1989-08-15	Kanegafuchi Kagaku Kogyo Kabushiki Kaisha	Process for preparing optically active 2-halo-1-phenyl ethanol
DK649787A (da) *	1986-12-23	1988-06-24	Hoffmann La Roche	Fremgangsmaade til fremstilling af optisk aktive smoersyrederivater
DE3942872A1 (de) *	1989-12-23	1991-06-27	Hoechst Ag	Verfahren zur enantioselektiven darstellung von ((omega)-1)-hydroxyalkylxanthinen

1989
- 1989-12-23 DE DE3942871A patent/DE3942871A1/de active Granted
1990
- 1990-12-19 DK DK90124747.8T patent/DK0435153T3/da active
- 1990-12-19 AT AT90124747T patent/ATE137237T1/de not_active IP Right Cessation
- 1990-12-19 EP EP90124747A patent/EP0435153B1/de not_active Expired - Lifetime
- 1990-12-19 DE DE59010302T patent/DE59010302D1/de not_active Expired - Fee Related
- 1990-12-19 ES ES90124747T patent/ES2086359T3/es not_active Expired - Lifetime
- 1990-12-21 JP JP2418029A patent/JPH07107063B2/ja not_active Expired - Lifetime
- 1990-12-21 US US07/631,415 patent/US5407815A/en not_active Expired - Fee Related
- 1990-12-21 KR KR1019900021298A patent/KR0179654B1/ko not_active Expired - Fee Related
1994
- 1994-05-12 US US08/241,717 patent/US5478831A/en not_active Expired - Fee Related
1996
- 1996-05-07 GR GR960401245T patent/GR3019860T3/el unknown

Also Published As

Publication number	Publication date
JPH04210688A (ja)	1992-07-31
KR0179654B1 (ko)	1999-03-20
DE59010302D1 (de)	1996-05-30
US5478831A (en)	1995-12-26
ATE137237T1 (de)	1996-05-15
GR3019860T3 (en)	1996-08-31
EP0435153B1 (de)	1996-04-24
KR910011854A (ko)	1991-08-07
DE3942871A1 (de)	1991-06-27
JPH07107063B2 (ja)	1995-11-15
EP0435153A2 (de)	1991-07-03
DE3942871C2 (da)	1992-11-05
EP0435153A3 (en)	1992-05-13
US5407815A (en)	1995-04-18
ES2086359T3 (es)	1996-07-01

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