DK0435362T3 - Præparat med et indhold af et ikke-steroidt, anti-inflammatorisk middel og et ikke-baktericidt virksomt tetracyclin - Google Patents

Præparat med et indhold af et ikke-steroidt, anti-inflammatorisk middel og et ikke-baktericidt virksomt tetracyclin

Info

Publication number
DK0435362T3
DK0435362T3 DK90203190.5T DK90203190T DK0435362T3 DK 0435362 T3 DK0435362 T3 DK 0435362T3 DK 90203190 T DK90203190 T DK 90203190T DK 0435362 T3 DK0435362 T3 DK 0435362T3
Authority
DK
Denmark
Prior art keywords
tetracycline
inflammatory agent
steroidal
bactericidal
amount
Prior art date
Application number
DK90203190.5T
Other languages
Danish (da)
English (en)
Inventor
Lorne M Golub
Thomas F Mcnamara
Nangavarum S Ramamurthy
Robert A Greenwald
Original Assignee
Univ New York State Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ New York State Res Found filed Critical Univ New York State Res Found
Application granted granted Critical
Publication of DK0435362T3 publication Critical patent/DK0435362T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/65—Tetracyclines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pain & Pain Management (AREA)
  • Obesity (AREA)
  • Dermatology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
DK90203190.5T 1989-12-04 1990-12-03 Præparat med et indhold af et ikke-steroidt, anti-inflammatorisk middel og et ikke-baktericidt virksomt tetracyclin DK0435362T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US44541089A 1989-12-04 1989-12-04

Publications (1)

Publication Number Publication Date
DK0435362T3 true DK0435362T3 (da) 1993-05-24

Family

ID=23768789

Family Applications (1)

Application Number Title Priority Date Filing Date
DK90203190.5T DK0435362T3 (da) 1989-12-04 1990-12-03 Præparat med et indhold af et ikke-steroidt, anti-inflammatorisk middel og et ikke-baktericidt virksomt tetracyclin

Country Status (8)

Country Link
US (2) US5321017A (de)
EP (1) EP0435362B1 (de)
JP (1) JP3016587B2 (de)
AT (1) ATE88346T1 (de)
CA (1) CA2031368C (de)
DE (1) DE69001429T2 (de)
DK (1) DK0435362T3 (de)
ES (1) ES2055309T3 (de)

Families Citing this family (66)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5308839A (en) * 1989-12-04 1994-05-03 The Research Foundation Of State University Of New York Composition comprising non-steroidal anti-inflammatory agent tenidap and effectively non-antibacterial tetracycline
US5523297A (en) * 1993-03-02 1996-06-04 The Research Foundation Of State University Of New York Inhibition of excessive phospholipase A2 activity and/or production by non-antimicrobial tetracyclines
US5668122A (en) * 1993-07-28 1997-09-16 Fife; Rose S. Method to treat cancer with tetracyclines
EP0736302A3 (de) * 1995-03-23 1997-06-04 Stichting Rega V Z W Proteaseinhibitoren, eine DNA-Konstruktion zur Expression einer Protease und ein Verfahren zur Messung der Protease und/oder Proteaseinhibitoren
EP0733369A1 (de) * 1995-03-23 1996-09-25 Stichting REGA V.Z.W. Protease-Inhibitoren, eine DNA-Konstruktion zur Expression einer Protease und ein Verfahren zur Messung Proteasen und/oder Proteaseinhibitoren
GB9608133D0 (en) * 1996-04-19 1996-06-26 Gemini International Holdings Diagnostic method and apparatus
US5827840A (en) * 1996-08-01 1998-10-27 The Research Foundation Of State University Of New York Promotion of wound healing by chemically-modified tetracyclines
US5837696A (en) * 1997-01-15 1998-11-17 The Research Foundation Of State University Of New York Method of inhibiting cancer growth
US6429204B1 (en) 1997-01-15 2002-08-06 University Of Miami Method of inhibiting cancer growth
US5773430A (en) * 1997-03-13 1998-06-30 Research Foundation Of State University Of New York Serine proteinase inhibitory activity by hydrophobic tetracycline
GB9714936D0 (en) * 1997-07-17 1997-09-17 Smith & Nephew Cell culture products
DK1041991T3 (da) * 1997-12-19 2008-07-28 Univ New York Ikke-antibakterielle tetracycliner til behandling af multipel sklerose
PT102160B (pt) * 1998-05-26 2001-04-30 Hovione Sociedade Quimica S A Processo para a preparacao de 4-(des-dimetilamino)-tetraciclinas
US6015804A (en) * 1998-09-11 2000-01-18 The Research Foundation Of State University Of New York Method of using tetracycline compounds to enhance interleukin-10 production
US5998390A (en) * 1998-09-28 1999-12-07 The Research Foundation Of State University Of New York Combination of bisphosphonate and tetracycline
US7067144B2 (en) * 1998-10-20 2006-06-27 Omeros Corporation Compositions and methods for systemic inhibition of cartilage degradation
US6946453B2 (en) 1998-11-18 2005-09-20 Collagenex Pharmaceuticals, Inc. 4-dedimethylaminotracycline derivatives
US6506740B1 (en) 1998-11-18 2003-01-14 Robert A. Ashley 4-dedimethylaminotetracycline derivatives
US9616150B2 (en) * 1999-10-29 2017-04-11 Children's Hospital Los Angeles Bone hemostasis method and materials
US20020132798A1 (en) * 2000-06-16 2002-09-19 Nelson Mark L. 7-phenyl-substituted tetracycline compounds
CA2447008A1 (en) * 2001-04-05 2002-10-24 Collagenex Pharmaceuticals, Inc. Controlled delivery of tetracycline compounds and tetracycline derivatives
US20060194773A1 (en) * 2001-07-13 2006-08-31 Paratek Pharmaceuticals, Inc. Tetracyline compounds having target therapeutic activities
EP1408987B1 (de) 2001-07-13 2013-04-10 Paratek Pharmaceuticals, Inc. Tetracyclin-verbindungen mit therapeutischen zielaktivitäten
WO2003053447A1 (en) * 2001-12-20 2003-07-03 Hanauske-Abel Hartmut M Treatment for averting or delaying premature delivery
US20030181371A1 (en) * 2001-12-28 2003-09-25 Angiotech Pharmaceuticals, Inc. Compositions and methods of using collajolie
EP2311797A1 (de) 2002-01-08 2011-04-20 Paratek Pharmaceuticals, Inc. 4-Dedimethylamin-Tetracyclinverbindungen
JP2005526754A (ja) 2002-03-08 2005-09-08 パラテック ファーマシューティカルズ インコーポレイテッド アミノメチル置換されたテトラサイクリン化合物
EP1503981A4 (de) 2002-03-21 2007-08-15 Paratek Pharm Innc Substituierte tetracyclinverbindungen
DE10227938B4 (de) * 2002-06-21 2006-07-20 Heraeus Kulzer Gmbh Pharmazeutische Zubereitung, Verfahren zu ihrer Herstellung sowie deren Verwendung
WO2004006850A2 (en) 2002-07-12 2004-01-22 Paratek Pharmaceuticals, Inc 3, 10, AND 12a SUBSTITUTED TETRACYCLINE COMPOUNDS
CA2521885C (en) * 2003-04-07 2013-06-25 Shire Laboratories, Inc. Once daily formulations of tetracyclines
WO2005009943A2 (en) 2003-07-09 2005-02-03 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds
JP4738333B2 (ja) 2003-07-09 2011-08-03 パラテック ファーマシューティカルズ インコーポレイテッド 9−アミノメチルテトラサイクリン化合物のプロドラッグ
EP2332904A3 (de) * 2004-01-15 2012-04-11 Paratek Pharmaceuticals, Inc. Derivate von Tetracyclin-Verbindungen
US7189456B2 (en) * 2004-03-04 2007-03-13 Transitions Optical, Inc. Photochromic optical article
US20060063745A1 (en) * 2004-09-22 2006-03-23 Charles Berman Composition for relieving pain and improving mobility
WO2006047756A2 (en) 2004-10-25 2006-05-04 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds
JP2008518025A (ja) 2004-10-25 2008-05-29 パラテック ファーマシューティカルズ インコーポレイテッド 4−アミノテトラサイクリンおよびその使用の方法
WO2006117660A2 (en) * 2005-05-04 2006-11-09 Clio Pharmaceutical Corporation Method for treating cancer, coronary, inflammatory and macular disease, combining the modulation of zinc- and/or copper dependent proteins
US8252776B2 (en) 2007-04-02 2012-08-28 Medicis Pharmaceutical Corporation Minocycline oral dosage forms for the treatment of acne
US8722650B1 (en) 2005-06-24 2014-05-13 Medicis Pharmaceutical Corporation Extended-release minocycline dosage forms
US7541347B2 (en) * 2007-04-02 2009-06-02 Medicis Pharmaceutical Coropration Minocycline oral dosage forms for the treatment of acne
US7544373B2 (en) * 2007-04-02 2009-06-09 Medicis Pharmaceutical Corporation Minocycline oral dosage forms for the treatment of acne
US20080242642A1 (en) * 2007-04-02 2008-10-02 Medicis Pharmaceutical Corporation Minocycline oral dosage forms for the treatment of acne
US9192615B2 (en) 2008-08-06 2015-11-24 Medicis Pharmaceutical Corporation Method for the treatment of acne and certain dosage forms thereof
US20080241235A1 (en) * 2007-04-02 2008-10-02 Medicis Pharmaceutical Corporation Minocycline oral dosage forms for the treatment of acne
US7919483B2 (en) * 2005-06-24 2011-04-05 Medicis Pharmaceutical Corporation Method for the treatment of acne
CA2616224A1 (en) * 2005-07-21 2007-02-01 Paratek Pharmaceuticals, Inc. 10-substituted tetracyclines and methods of use thereof
BRPI0602372B8 (pt) 2006-05-18 2021-06-22 Einco Biomaterial Ltda processo de preparação de compósitos em base de biocerâmicas e polímeros biodegradáveis e produto derivado
IL270446B2 (en) * 2006-12-21 2023-10-01 Paratek Pharm Innc A tetracycline compound, a pharmaceutical preparation containing the tetracycline compound, and the tetracycline compound or the pharmaceutical preparation for the treatment of the tetracycline-responsive condition
PL2120963T3 (pl) 2006-12-21 2019-05-31 Paratek Pharm Innc Podstawione związki tetracyklinowe do leczenia zaburzeń zapalnych skóry
US20080241197A1 (en) * 2007-04-02 2008-10-02 Medicis Pharmaceutical Corporation Minocycline dosage forms for the treatment of acne
EP2144870A2 (de) * 2007-04-27 2010-01-20 Paratek Pharmaceuticals, Inc. Verfahren zur synthese und reinigung von aminoalkyl-tetracyclin-verbindungen
WO2009009042A1 (en) * 2007-07-06 2009-01-15 Paratek Pharmaceuticals, Inc. Methods for synthesizing substituted tetracycline compounds
TWI585071B (zh) 2008-05-19 2017-06-01 派洛泰克藥物股份有限公司 四環素化合物之甲苯磺酸鹽及同素異形體
HUE026562T2 (hu) 2008-08-08 2016-06-28 Tetraphase Pharmaceuticals Inc C7-fluor-helyettesített tetraciklin vegyületek
EP2341771A4 (de) * 2008-09-19 2012-08-15 Paratek Pharm Innc Tetracyclinverbindungen zur behandlung rheumatoider arthritis sowie entsprechende behandlungsverfahren
CN102459153A (zh) 2009-05-08 2012-05-16 四相制药公司 四环素类化合物
EP2470500B1 (de) 2009-08-28 2017-10-04 Tetraphase Pharmaceuticals, Inc. Tetracyclinverbindungen
WO2011123536A1 (en) 2010-03-31 2011-10-06 Tetraphase Pharmaceuticals, Inc. Polycyclic tetracycline compounds
US9561241B1 (en) 2011-06-28 2017-02-07 Medicis Pharmaceutical Corporation Gastroretentive dosage forms for minocycline
TR201902057T4 (tr) 2012-08-31 2019-03-21 Tetraphase Pharmaceuticals Inc Tetrasiklin bileşikleri.
FI3487996T3 (fi) 2016-07-21 2024-07-10 Novozymes As Seriiniproteaasivariantteja ja niitä koodittavia polynukleotideja
CN109661465A (zh) 2016-07-21 2019-04-19 诺维信公司 丝氨酸蛋白酶变体以及对其进行编码的多核苷酸
MA46567A (fr) 2016-10-19 2019-08-28 Tetraphase Pharmaceuticals Inc Formes cristallines de l'éravacycline
WO2020097450A1 (en) 2018-11-09 2020-05-14 Tetraphase Pharmaceuticals, Inc. Polymorphic forms of a compound and uses thereof

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3304227A (en) * 1965-07-15 1967-02-14 Loyal E Loveless Antibiotic-containing animal feed
US3787324A (en) * 1971-03-01 1974-01-22 Warner Lambert Co 4-hydroxy-3-(3-isoxazolocarbamyl)-2h-1,2-benzothiazine 1,dioxides and process for their production
US4049700A (en) * 1976-06-17 1977-09-20 The Upjohn Company Ibuprofen p-hydroxyphenylurea ester
US4189497A (en) * 1977-11-22 1980-02-19 American Cyanamid Company Method of treating arthritic disease
US4269832A (en) * 1978-04-12 1981-05-26 American Cyanamid Company Method of treating arthritic disease
US4218449A (en) * 1978-08-21 1980-08-19 John R. A. Simoons Treatment of rheumatoid arthritis and related diseases
US4704383A (en) * 1983-12-29 1987-11-03 The Research Foundation Of State University Of New York Non-antibacterial tetracycline compositions possessing anti-collagenolytic properties and methods of preparing and using same
US4935412A (en) * 1983-12-29 1990-06-19 The Research Foundation Of State University Of New York Non-antibacterial tetracycline compositions possessing anti-collagenolytic properties and methods of preparing and using same
US4666897A (en) * 1983-12-29 1987-05-19 Research Foundation Of State University Inhibition of mammalian collagenolytic enzymes by tetracyclines
US4925833A (en) * 1983-12-29 1990-05-15 The Research Foundation Of State University Of New York Use of tetracycline to enhance bone protein synthesis and/or treatment of osteoporosis
US4677132A (en) * 1986-03-12 1987-06-30 American Home Products Corporation Inhibition of bone resorption by etodolac
US5045538A (en) * 1990-06-28 1991-09-03 The Research Foundation Of State University Of New York Inhibition of wasting and protein degradation of mammalian muscle by tetracyclines

Also Published As

Publication number Publication date
JP3016587B2 (ja) 2000-03-06
US5459135A (en) 1995-10-17
EP0435362B1 (de) 1993-04-21
ES2055309T3 (es) 1994-08-16
CA2031368A1 (en) 1991-06-05
DE69001429D1 (de) 1993-05-27
EP0435362A1 (de) 1991-07-03
JPH03227931A (ja) 1991-10-08
US5321017A (en) 1994-06-14
ATE88346T1 (de) 1993-05-15
CA2031368C (en) 2002-01-29
DE69001429T2 (de) 1993-07-29

Similar Documents

Publication Publication Date Title
DE69001429D1 (de) Zusammensetzung mit gehalt an einem nichtsteroiden entzuendungshemmenden mittel und einem nichtbakterizidwirksamen tetracyclin.
CA2105529A1 (en) Composition comprising non-steroidal anti-inflammatory agent and effectively non-antibacterial tetracycline
MX9204381A (es) Metodo para tratar inflamacion ocular
FI962249A7 (fi) Substituoituja pyratsolyylibentseenisulfonamideja tulehduksen hoitoa varten
ATE39323T1 (de) Injizierbare loesung zur behandlung von entzuendungen.
ES2166110T3 (es) Agonistas no alostericos de gabaa para tratar trastornos del sueño.
NO943663L (no) Forbindelser som kan anvendes for behandling av allergiske sykdommer og betennelsessykdommer
FI945426L (fi) GABA- ja L-glutamiinihappoanalogit kohtauksenvastaiseen käsittelyyn
PL323825A1 (en) Peptidyloheterocycli compounds useful in treating diorders associated with thrombosin
ATE84723T1 (de) Zusammensetzungen gegen durchfall und ihre anwendung.
DE122009000012I1 (de) Substituierte pyrazolyl-benzolsulfonamide zur behandlung von entzundungen.
PT772600E (pt) Compostos de imidazolilo substituido nas posicoes 1 e 2 para o tratamento da inflamacao
DK0533213T3 (da) Anvendelse af det aktive middel azelastin og glycerolethere til bekæmpelse af psoriasis
ATE26215T1 (de) Steigerung der intranasalen absorption von calcitonin durch dessen formulierung mit oberflaechenaktiven mitteln.
DK0888323T3 (da) Dihydrobenzofuran og beslægtede forbindelser, der er nyttige som antiinflammatoriske midler
BR0112212A (pt) Uma combinação de inibidores de fbpase e agentes antidiabéticos úteis para o tratamento de diabetes
FI870026A0 (fi) Med ljuddaempningsspringor och bett i foertillslutningsoeppningarna foersedd kranventil.
GB2090529A (en) Thrombosis-prophylactic and curing agent
ATE113207T1 (de) Benzamid gegen kognitive erkrankungen.
ES520218A0 (es) Un procedimiento para la preparacion de nuevos 2,3-diaril-5-halotiofenos.
DK165938C (da) Topisk middel til behandling af non-inflammatorisk acne
DK0888330T3 (da) Fremgangsmåder til behandling eller forebyggelse af interstitiel cystitis
DK213484A (da) Farmaceutisk middel til behandling af slagtilfaelde og lignende krampesygdomme
FI852730A0 (fi) (pyrrol-1-yl) -fenyl-dihydropyridazinoner, deras framstaellning och anvaendning.
FI895229A7 (fi) Yhdisteitä virtsan pidätyskyvyttömyyden hoitoon