DK0442348T3 - Nye imidazolforbindelser, fremgangsmåder til deres fremstilling, lægemidler på basis af disse forbindelser samt nogle mellemprodukter - Google Patents

Nye imidazolforbindelser, fremgangsmåder til deres fremstilling, lægemidler på basis af disse forbindelser samt nogle mellemprodukter

Info

Publication number: DK0442348T3
Authority: DK; Denmark
Prior art keywords: alkyl; opt; substd; compounds; heteroatom
Prior art date: 1990-02-10

Application number

DK91101497.5T

Other languages

Danish (da)

English (en)

Inventor

Rolf Dr Graeve

Ismahan Dr Okyayuz-Baklouti

Dirk Dr Seiffge

Original Assignee

Hoechst Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-02-10

Filing date

1991-02-05

Publication date

1996-11-11

1991-02-05 Application filed by Hoechst Ag filed Critical Hoechst Ag

1996-11-11 Application granted granted Critical

1996-11-11 Publication of DK0442348T3 publication Critical patent/DK0442348T3/da

Links

150000002460 imidazoles Chemical class 0.000 title abstract 2
150000001875 compounds Chemical class 0.000 title 1
239000003814 drug Substances 0.000 title 1
229940079593 drug Drugs 0.000 title 1
239000000543 intermediate Substances 0.000 title 1
125000000217 alkyl group Chemical group 0.000 abstract 8
RAXXELZNTBOGNW-UHFFFAOYSA-N imidazole Natural products C1=CNC=N1 RAXXELZNTBOGNW-UHFFFAOYSA-N 0.000 abstract 5
125000005842 heteroatom Chemical group 0.000 abstract 3
125000000623 heterocyclic group Chemical group 0.000 abstract 3
YNAVUWVOSKDBBP-UHFFFAOYSA-N Morpholine Chemical compound C1COCCN1 YNAVUWVOSKDBBP-UHFFFAOYSA-N 0.000 abstract 2
125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 2
229910052760 oxygen Inorganic materials 0.000 abstract 2
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
229910052717 sulfur Inorganic materials 0.000 abstract 2
RVWUTALYYJTSRD-UHFFFAOYSA-N 1-methyl-n-(2-morpholin-4-ylethyl)imidazole-2-sulfonamide Chemical compound CN1C=CN=C1S(=O)(=O)NCCN1CCOCC1 RVWUTALYYJTSRD-UHFFFAOYSA-N 0.000 abstract 1
BSAUSFFXHLPDDZ-UHFFFAOYSA-N 1-methyl-n-(2-morpholin-4-ylpropyl)imidazole-4-sulfonamide Chemical compound C1COCCN1C(C)CNS(=O)(=O)C1=CN(C)C=N1 BSAUSFFXHLPDDZ-UHFFFAOYSA-N 0.000 abstract 1
101100516563 Caenorhabditis elegans nhr-6 gene Proteins 0.000 abstract 1
125000004183 alkoxy alkyl group Chemical group 0.000 abstract 1
125000003545 alkoxy group Chemical group 0.000 abstract 1
125000000304 alkynyl group Chemical group 0.000 abstract 1
125000002950 monocyclic group Chemical group 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
229920006395 saturated elastomer Polymers 0.000 abstract 1
125000004434 sulfur atom Chemical group 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/84—Sulfur atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Hematology (AREA)
Diabetes (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Epoxy Resins (AREA)
Cosmetics (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Detergent Compositions (AREA)

DK91101497.5T 1990-02-10 1991-02-05 Nye imidazolforbindelser, fremgangsmåder til deres fremstilling, lægemidler på basis af disse forbindelser samt nogle mellemprodukter DK0442348T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE4004061A DE4004061A1 (de)	1990-02-10	1990-02-10	Neue imidazolverbindungen, verfahren zu deren herstellung, arzneimittel auf basis dieser verbindungen sowie einige zwischenprodukte

Publications (1)

Publication Number	Publication Date
DK0442348T3 true DK0442348T3 (da)	1996-11-11

Family

ID=6399847

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK91101497.5T DK0442348T3 (da)	1990-02-10	1991-02-05	Nye imidazolforbindelser, fremgangsmåder til deres fremstilling, lægemidler på basis af disse forbindelser samt nogle mellemprodukter

Country Status (23)

Country	Link
US (2)	US5232922A (fr)
EP (1)	EP0442348B1 (fr)
JP (1)	JP3026847B2 (fr)
KR (1)	KR910015547A (fr)
CN (1)	CN1053919A (fr)
AT (1)	ATE140452T1 (fr)
AU (1)	AU634342B2 (fr)
BR (1)	BR9100520A (fr)
CA (1)	CA2035988A1 (fr)
CS (1)	CS30991A2 (fr)
DE (2)	DE4004061A1 (fr)
DK (1)	DK0442348T3 (fr)
ES (1)	ES2090150T3 (fr)
FI (1)	FI910602L (fr)
GR (1)	GR3020570T3 (fr)
HU (1)	HU207997B (fr)
IE (1)	IE910427A1 (fr)
IL (1)	IL97195A0 (fr)
MX (1)	MX24463A (fr)
NO (1)	NO910496L (fr)
NZ (1)	NZ237049A (fr)
PT (1)	PT96710A (fr)
ZA (1)	ZA91948B (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2000006159A1 (fr) *	1998-07-31	2000-02-10	Eli Lilly And Company	Derives de sulfamide heterocycliques
WO2006105127A2 (fr) *	2005-03-31	2006-10-05	Takeda San Diego, Inc.	Inhibiteurs de l'hydroxysteroide deshydrogenase
BR102016023153A2 (pt) *	2016-10-04	2018-05-02	Fundação Butantan	Composição, uso, e, método para tratar doenças neurodegenerativas
WO2018069237A1 (fr) *	2016-10-12	2018-04-19	Basf Se	Bétaïne et procédé pour sa fabrication

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2603649A (en) *	1950-04-04	1952-07-15	American Cyanamid Co	Heterocyclic sulfonamides and method of preparing the same
US3932444A (en) *	1972-04-28	1976-01-13	E. I. Du Pont De Nemours & Co.	4-Imidazolylsulfonylimidazoles
ATE35265T1 (de) *	1982-05-28	1988-07-15	Ciba Geigy Ag	Neue sulfonyl(thio)harnstoffe, verfahren zu deren herstellung und deren verwendung als herbizide und/oder wachstumsregulatoren.
EP0095925B2 (fr) *	1982-06-01	1994-12-07	E.I. Du Pont De Nemours And Company	Dérivés d'imidazole, pyrazole, thiazole et isothiazole à activité herbicide
EP0105575B1 (fr) *	1982-07-12	1987-03-04	G.D. Searle & Co.	Composés 1-(1H-imidazolyliques), 1-N-morpholinyliques et pyridyliques, leur préparation et compositions pharmaceutiques les contenant
CA1222752A (fr) *	1983-05-18	1987-06-09	Beat Bohner	Sulfonylurees et sulfonylthiourees; preparation; utilisation comme herbicides et (ou) regulateurs de croissance
DE3504677A1 (de) *	1985-02-12	1986-08-14	A. Nattermann & Cie GmbH, 5000 Köln	Neue imidazol-2-yloxyalkansaeuren und ihre derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
US4830660A (en) *	1986-06-19	1989-05-16	Nissan Chemical Industries, Ltd.	Imidazolesulfonamide derivatives and herbicides
CA1339133C (fr) *	1987-03-13	1997-07-29	Rikuo Nasu	Derives de l'imidazole et compositions a base de ces derives pour l'elimination d'organismes nuisibles
EP0284277A1 (fr) *	1987-03-21	1988-09-28	AgrEvo UK Limited	Fongicides de cyanoimidazole

1990
- 1990-02-10 DE DE4004061A patent/DE4004061A1/de not_active Withdrawn
1991
- 1991-02-05 DK DK91101497.5T patent/DK0442348T3/da active
- 1991-02-05 DE DE59107999T patent/DE59107999D1/de not_active Expired - Lifetime
- 1991-02-05 AT AT91101497T patent/ATE140452T1/de not_active IP Right Cessation
- 1991-02-05 ES ES91101497T patent/ES2090150T3/es not_active Expired - Lifetime
- 1991-02-05 EP EP91101497A patent/EP0442348B1/fr not_active Expired - Lifetime
- 1991-02-07 FI FI910602A patent/FI910602L/fi unknown
- 1991-02-07 BR BR919100520A patent/BR9100520A/pt unknown
- 1991-02-08 KR KR1019910002129A patent/KR910015547A/ko not_active Withdrawn
- 1991-02-08 ZA ZA91948A patent/ZA91948B/xx unknown
- 1991-02-08 MX MX2446391A patent/MX24463A/es unknown
- 1991-02-08 CA CA002035988A patent/CA2035988A1/fr not_active Abandoned
- 1991-02-08 AU AU70848/91A patent/AU634342B2/en not_active Ceased
- 1991-02-08 NZ NZ237049A patent/NZ237049A/en unknown
- 1991-02-08 IE IE042791A patent/IE910427A1/en unknown
- 1991-02-08 IL IL97195A patent/IL97195A0/xx unknown
- 1991-02-08 HU HU91415A patent/HU207997B/hu not_active IP Right Cessation
- 1991-02-08 NO NO91910496A patent/NO910496L/no unknown
- 1991-02-08 PT PT96710A patent/PT96710A/pt unknown
- 1991-02-08 JP JP3060750A patent/JP3026847B2/ja not_active Expired - Lifetime
- 1991-02-08 US US07/652,606 patent/US5232922A/en not_active Expired - Lifetime
- 1991-02-08 CS CS91309A patent/CS30991A2/cs unknown
- 1991-02-09 CN CN91100969A patent/CN1053919A/zh active Pending
1993
- 1993-05-07 US US08/057,887 patent/US5356922A/en not_active Expired - Lifetime
1996
- 1996-07-18 GR GR960401776T patent/GR3020570T3/el unknown

Also Published As

Publication number	Publication date
AU7084891A (en)	1991-08-15
IL97195A0 (en)	1992-05-25
ATE140452T1 (de)	1996-08-15
US5356922A (en)	1994-10-18
EP0442348A3 (en)	1992-03-04
NO910496D0 (no)	1991-02-08
HU910415D0 (en)	1991-08-28
FI910602A7 (fi)	1991-08-11
AU634342B2 (en)	1993-02-18
CS30991A2 (en)	1991-09-15
US5232922A (en)	1993-08-03
ZA91948B (en)	1991-10-30
HU207997B (en)	1993-07-28
IE910427A1 (en)	1991-08-14
EP0442348B1 (fr)	1996-07-17
JP3026847B2 (ja)	2000-03-27
ES2090150T3 (es)	1996-10-16
CN1053919A (zh)	1991-08-21
CA2035988A1 (fr)	1991-08-11
DE4004061A1 (de)	1991-08-14
JPH04316561A (ja)	1992-11-06
EP0442348A2 (fr)	1991-08-21
KR910015547A (ko)	1991-09-30
BR9100520A (pt)	1991-10-29
MX24463A (es)	1993-06-01
NO910496L (no)	1991-08-12
DE59107999D1 (de)	1996-08-22
GR3020570T3 (en)	1996-10-31
HUT56549A (en)	1991-09-30
FI910602A0 (fi)	1991-02-07
NZ237049A (en)	1992-10-28
FI910602L (fi)	1991-08-11
PT96710A (pt)	1991-10-31

Publication	Publication Date	Title
DZ1467A1 (fr)	2004-09-13	Dérivés d'acides amines.
ES2139638T3 (es)	2000-02-16	1,4-piperazinas disustituidas para el tratamiento de las enfermedades del sistema nervioso central y de las enfermedades neuroendocrinas.
GR3005586T3 (fr)	1993-06-07
DE69305642D1 (de)	1996-11-28	Injizierbares Arzneimittel und Satz, die Omoprazol oder verwandte Verbindungenenthalten
BR0210077A (pt)	2004-06-22	Composto, seus sais, solvatos e ésteres hidrolisáveis farmaceuticamente aceitáveis, composição farmacêutica, uso de um composto, e, método de tratamento de uma doença ou condição mediada por hppar alfa
SE8801729D0 (sv)	1988-05-06	Purine derivatives for use in therapy
ES2133324T3 (es)	1999-09-16	Compuestos de dibenzoxazepina sustituidos, composiciones farmaceuticas y metodos de uso.
FI910602A0 (fi)	1991-02-07	Nya imidazolfoereningar, foerfarande foer deras framstaellning laekemedel baserade pao dessa foereningar samt naogra mellanprodukter.
FI862251A0 (fi)	1986-05-28	Spiro-imidazolidiner som inhibitorer foer aldosreduktas.
DK520787A (da)	1988-04-07	Terapeutisk middel indeholdende propentofyllin eller derivater deraf til brug ved behandling af peptisk ulcus
DE3687703D1 (de)	1993-03-18	Cephalosporinderivate und sie enthaltende antibiotika.
DK17581A (da)	1981-07-17	2,3-dihydro-imidazo (1,2-b) pyridaziner fremgangsmaade til deres fremstilling samt deres anvendelse
ES8101045A1 (es)	1980-12-01	Procedimiento para la preparacion de derivados de acidos pi-rrolidinilsulfamoilbenzoicos sustituidos
DK0413278T3 (da)	1997-04-07	Anvendelse af xanthinderivater mod mavesår
ES464729A1 (es)	1978-09-01	Un procedimiento para la preparacion de benzisotiazolonas amino-alquil sustituidas.
EP0653207A4 (fr)	1995-03-06	Composition inhibitrice d'une infection par le virus du sida.
PT87954A (pt)	1989-06-30	Processo para a preparacao de composicoes farmaceuticas contendo derivados de dioxopiperidina, com efeito antipsicotico
FR2285887A1 (fr)	1976-04-23	2-(3-trifluoromethyl) phenyl tetrahydro 1,4-oxazines substituees et leur application a titre de medicament du systeme nerveux central
ES2062752T3 (es)	1994-12-16	Preparado de una sal de oxipurinol en forma oral para el tratamiento de hiperuricemia.
NL7510483A (en)	1977-03-08	Alpha-ureido-thienylacetamido-cephalosporanic acids - with broad-spectrum antibacterial activity for oral or parenteral admin., for disinfection and as additives for animal feeds
DK361586A (da)	1987-02-01	Acetohydroxamsyre-derivat, fremgangsmaade til fremstilling af dette samt terapeutisk middel indeholdende dette
DE68900634D1 (de)	1992-02-13	Tiermedizinische zusammensetzung.