DK0452850T3 - 4-[3-(Oxothiazoldinyl)]butynylaminer, fremgangsmåde til deres fremstilling og deres anvendelse som lægemidler - Google Patents

4-[3-(Oxothiazoldinyl)]butynylaminer, fremgangsmåde til deres fremstilling og deres anvendelse som lægemidler

Info

Publication number: DK0452850T3
Authority: DK; Denmark
Prior art keywords: oxothiazoldinyl; butynylamines; pharmaceuticals; preparation
Prior art date: 1990-04-16

Application number

DK91105972T

Other languages

English (en)

Inventor

Nicholas J Hrib

Original Assignee

Hoechst Marion Roussel Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-04-16

Filing date

1991-04-15

Publication date

1998-09-23

1991-04-15 Application filed by Hoechst Marion Roussel Inc filed Critical Hoechst Marion Roussel Inc

1998-09-23 Application granted granted Critical

1998-09-23 Publication of DK0452850T3 publication Critical patent/DK0452850T3/da

Links

239000003814 drug Substances 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D277/12—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/14—Oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/10—Spiro-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Pain & Pain Management (AREA)
Bioinformatics & Cheminformatics (AREA)
Neurology (AREA)
Cardiology (AREA)
Biomedical Technology (AREA)
Heart & Thoracic Surgery (AREA)
Neurosurgery (AREA)
Rheumatology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Thiazole And Isothizaole Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)

DK91105972T 1990-04-16 1991-04-15 4-[3-(Oxothiazoldinyl)]butynylaminer, fremgangsmåde til deres fremstilling og deres anvendelse som lægemidler DK0452850T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US07/509,280 US5034392A (en)	1990-04-16	1990-04-16	4-(3-(4-oxothiazolidinyl)butynylamines

Publications (1)

Publication Number	Publication Date
DK0452850T3 true DK0452850T3 (da)	1998-09-23

Family

ID=24025983

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK91105972T DK0452850T3 (da)	1990-04-16	1991-04-15	4-[3-(Oxothiazoldinyl)]butynylaminer, fremgangsmåde til deres fremstilling og deres anvendelse som lægemidler

Country Status (26)

Country	Link
US (1)	US5034392A (da)
EP (1)	EP0452850B1 (da)
JP (1)	JPH07119223B2 (da)
KR (1)	KR0163598B1 (da)
AR (1)	AR248402A1 (da)
AT (1)	ATE163010T1 (da)
AU (1)	AU636972B2 (da)
BG (1)	BG60066B2 (da)
CA (1)	CA2040489C (da)
CZ (1)	CZ284447B6 (da)
DE (1)	DE69128845T2 (da)
DK (1)	DK0452850T3 (da)
ES (1)	ES2112844T3 (da)
FI (1)	FI94755C (da)
GR (1)	GR3026319T3 (da)
HU (1)	HUT61017A (da)
IE (1)	IE911257A1 (da)
IL (1)	IL97852A (da)
MX (1)	MX25359A (da)
NO (1)	NO300134B1 (da)
NZ (1)	NZ237811A (da)
PL (1)	PL165488B1 (da)
PT (1)	PT97371B (da)
RO (1)	RO108683B1 (da)
RU (1)	RU2001914C1 (da)
ZA (1)	ZA912783B (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5273977A (en) *	1990-11-05	1993-12-28	Warner-Lambert Company	Substituted tetrahydropyridines and hydroxypiperidines as central nervous system agents
US5147881A (en) *	1990-11-14	1992-09-15	Pfizer Inc	4-(1,2-benzisoxazolyl)piperidine antipsychotic agents
US5130315A (en) *	1991-01-10	1992-07-14	Raymond R. Wittekind	1-piperazinyl-2-butenes and -2-butynes
US5194436A (en) *	1991-01-10	1993-03-16	Hoechst-Roussel Pharmaceuticals Inc.	1-piperazinyl-2-butenes and -2-butynes

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3354178A (en) *	1965-04-09	1967-11-21	Sterling Drug Inc	Nu-(4-amino-2-butynyl)-nu-alkylcarboxamides
EP0316723B1 (en) *	1987-11-20	1992-09-30	Hoechst-Roussel Pharmaceuticals Incorporated	3-[4(1-Substituted-4-piperazinyl)butyl]-4-thiazolidinones a process for their preparation and their use as medicaments

1990
- 1990-04-16 US US07/509,280 patent/US5034392A/en not_active Expired - Lifetime
1991
- 1991-04-09 BG BG094208A patent/BG60066B2/bg unknown
- 1991-04-12 AR AR91319454A patent/AR248402A1/es active
- 1991-04-12 FI FI911783A patent/FI94755C/fi not_active IP Right Cessation
- 1991-04-12 NZ NZ237811A patent/NZ237811A/en unknown
- 1991-04-12 RO RO147316A patent/RO108683B1/ro unknown
- 1991-04-15 AU AU75028/91A patent/AU636972B2/en not_active Ceased
- 1991-04-15 EP EP91105972A patent/EP0452850B1/en not_active Expired - Lifetime
- 1991-04-15 CA CA002040489A patent/CA2040489C/en not_active Expired - Fee Related
- 1991-04-15 IE IE125791A patent/IE911257A1/en not_active IP Right Cessation
- 1991-04-15 PT PT97371A patent/PT97371B/pt not_active IP Right Cessation
- 1991-04-15 ES ES91105972T patent/ES2112844T3/es not_active Expired - Lifetime
- 1991-04-15 PL PL91289892A patent/PL165488B1/pl unknown
- 1991-04-15 CZ CS911065A patent/CZ284447B6/cs not_active IP Right Cessation
- 1991-04-15 IL IL9785291A patent/IL97852A/en not_active IP Right Cessation
- 1991-04-15 ZA ZA912783A patent/ZA912783B/xx unknown
- 1991-04-15 DE DE69128845T patent/DE69128845T2/de not_active Expired - Fee Related
- 1991-04-15 RU SU914895050A patent/RU2001914C1/ru active
- 1991-04-15 HU HU911239A patent/HUT61017A/hu unknown
- 1991-04-15 DK DK91105972T patent/DK0452850T3/da active
- 1991-04-15 JP JP3109867A patent/JPH07119223B2/ja not_active Expired - Fee Related
- 1991-04-15 MX MX25359A patent/MX25359A/es unknown
- 1991-04-15 NO NO911465A patent/NO300134B1/no unknown
- 1991-04-15 AT AT91105972T patent/ATE163010T1/de not_active IP Right Cessation
- 1991-04-15 KR KR1019910005987A patent/KR0163598B1/ko not_active Expired - Fee Related
1998
- 1998-03-11 GR GR980400510T patent/GR3026319T3/el unknown

Also Published As

Publication number	Publication date
NO911465L (no)	1991-10-17
PT97371A (pt)	1992-01-31
CS9101065A2 (en)	1991-11-12
JPH07119223B2 (ja)	1995-12-20
FI911783A7 (fi)	1991-10-17
PL289892A1 (en)	1992-07-27
FI94755B (fi)	1995-07-14
NO911465D0 (no)	1991-04-15
BG60066B2 (bg)	1993-09-30
EP0452850B1 (en)	1998-02-04
EP0452850A1 (en)	1991-10-23
GR3026319T3 (en)	1998-06-30
ZA912783B (en)	1991-12-24
RO108683B1 (ro)	1994-07-29
HU911239D0 (en)	1991-10-28
KR910018367A (ko)	1991-11-30
PL165488B1 (pl)	1994-12-30
IL97852A0 (en)	1992-06-21
CA2040489C (en)	2003-06-10
DE69128845D1 (de)	1998-03-12
FI94755C (fi)	1995-10-25
HUT61017A (en)	1992-11-30
PT97371B (pt)	1998-08-31
IL97852A (en)	1994-11-28
ATE163010T1 (de)	1998-02-15
AU636972B2 (en)	1993-05-13
CZ284447B6 (cs)	1998-11-11
NO300134B1 (no)	1997-04-14
ES2112844T3 (es)	1998-04-16
RU2001914C1 (ru)	1993-10-30
KR0163598B1 (ko)	1998-12-01
MX25359A (es)	1994-05-31
FI911783A0 (fi)	1991-04-12
JPH04234879A (ja)	1992-08-24
CA2040489A1 (en)	1991-10-17
NZ237811A (en)	1993-12-23
US5034392A (en)	1991-07-23
AU7502891A (en)	1991-10-17
DE69128845T2 (de)	1998-07-09
AR248402A1 (es)	1995-08-18
IE911257A1 (en)	1991-10-23

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