DK0676409T3 - Erythromycinderivater, fremgangsmåde til deres fremstilling og deres anvendelse som lægemidler - Google Patents

Erythromycinderivater, fremgangsmåde til deres fremstilling og deres anvendelse som lægemidler

Info

Publication number
DK0676409T3
DK0676409T3 DK95400763T DK95400763T DK0676409T3 DK 0676409 T3 DK0676409 T3 DK 0676409T3 DK 95400763 T DK95400763 T DK 95400763T DK 95400763 T DK95400763 T DK 95400763T DK 0676409 T3 DK0676409 T3 DK 0676409T3
Authority
DK
Denmark
Prior art keywords
pharmaceuticals
processes
preparation
erythromycin derivatives
erythromycin
Prior art date
Application number
DK95400763T
Other languages
English (en)
Inventor
Jean-Francois Chantot
Martret Odile Le
Constantin Agouridas
Alexis Denis
Yannick Benedetti
Original Assignee
Aventis Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa
Application granted granted Critical
Publication of DK0676409T3 publication Critical patent/DK0676409T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08Hetero rings containing eight or more ring members, e.g. erythromycins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK95400763T 1994-04-08 1995-04-06 Erythromycinderivater, fremgangsmåde til deres fremstilling og deres anvendelse som lægemidler DK0676409T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9404154A FR2718450B1 (fr) 1994-04-08 1994-04-08 Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.

Publications (1)

Publication Number Publication Date
DK0676409T3 true DK0676409T3 (da) 2003-06-23

Family

ID=9461886

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95400763T DK0676409T3 (da) 1994-04-08 1995-04-06 Erythromycinderivater, fremgangsmåde til deres fremstilling og deres anvendelse som lægemidler

Country Status (49)

Country Link
US (2) US5656607A (da)
EP (1) EP0676409B1 (da)
JP (1) JP3000023B2 (da)
KR (1) KR100317148B1 (da)
CN (1) CN1059445C (da)
AP (1) AP587A (da)
AT (1) ATE234853T1 (da)
AU (1) AU684939B2 (da)
BG (1) BG61916B1 (da)
BR (1) BR9506147A (da)
CA (1) CA2164638C (da)
CO (1) CO4370097A1 (da)
CZ (1) CZ296005B6 (da)
DE (1) DE69529934T2 (da)
DK (1) DK0676409T3 (da)
DZ (1) DZ1869A1 (da)
EE (1) EE04498B1 (da)
ES (1) ES2189820T3 (da)
FI (1) FI111264B (da)
FR (1) FR2718450B1 (da)
GB (1) GB2288174A (da)
GE (1) GEP19991836B (da)
HR (1) HRP950217B1 (da)
HU (1) HU215396B (da)
IL (1) IL112954A (da)
IS (1) IS1865B (da)
JO (1) JO1850B1 (da)
LV (1) LV11182B (da)
MA (1) MA23501A1 (da)
MD (1) MD663G2 (da)
MY (1) MY114672A (da)
NO (1) NO308361B1 (da)
NZ (1) NZ284498A (da)
OA (1) OA10200A (da)
PE (1) PE2896A1 (da)
PL (1) PL180837B1 (da)
PT (1) PT676409E (da)
RO (1) RO115634B1 (da)
RU (1) RU2141965C1 (da)
SA (1) SA97170757A (da)
SI (1) SI0676409T1 (da)
SK (1) SK284079B6 (da)
SV (1) SV1995000018A (da)
TN (1) TNSN95026A1 (da)
TW (1) TW316908B (da)
UA (1) UA44705C2 (da)
WO (1) WO1995027720A1 (da)
YU (1) YU49221B (da)
ZA (1) ZA952059B (da)

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CA2253451A1 (en) * 1996-05-07 1997-11-13 Abbott Laboratories 3-descladinose-2,3-anhydroerythromycin derivatives
US5750510A (en) * 1997-04-04 1998-05-12 Abbott Laboratories 3-descladinose-2,3-anhydroerythromycin derivatives
FR2748746B1 (fr) * 1996-05-14 1998-08-14 Hoechst Marion Roussel Inc Nouveau procede d'isomerisation du radical methyle en 10 de derives de l'erythromycine
FR2751656B1 (fr) * 1996-07-24 1998-10-16 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
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FR2757168B1 (fr) * 1996-12-12 1999-06-11 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
FR2760017B1 (fr) * 1997-02-27 1999-04-30 Hoechst Marion Roussel Inc Nouveaux derives de l'erytromycine, leur procede de preparation et leur application comme medicaments
WO1998040392A1 (fr) * 1997-03-10 1998-09-17 Taisho Pharmaceutical Co., Ltd. Derives d'erythromycine a
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FR2786188B1 (fr) * 1998-11-24 2002-10-31 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur applicaion comme medicaments
EP1749832A3 (en) * 1998-12-10 2008-03-26 Pfizer Products Incorporated Carbamate and carbazate ketolide antibiotics
ES2273964T3 (es) 1998-12-10 2007-05-16 Pfizer Products Inc. Antibioticos de carbamato y carbazato cetolida.
EP1298138B1 (en) * 1998-12-10 2006-11-02 Pfizer Products Inc. Carbamate and Carbazate Ketolide Antibiotics
FR2789392B1 (fr) * 1999-02-04 2001-10-05 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
US6054435A (en) * 1999-03-19 2000-04-25 Abbott Laboratories 6-O-substituted macrolides having antibacterial activity
IL145976A0 (en) 1999-04-16 2002-07-25 Ortho Mcneil Pharm Inc Ketolide antibacterials
US6590083B1 (en) 1999-04-16 2003-07-08 Ortho-Mcneil Pharmaceutical, Inc. Ketolide antibacterials
US6395710B1 (en) * 1999-04-16 2002-05-28 Kosan Biosciences, Inc. Macrolide antiinfective agents
IL145739A0 (en) * 1999-05-24 2002-07-25 Pfizer Prod Inc 13-methyl-erythromycin derivatives
JP4509553B2 (ja) * 2001-07-03 2010-07-21 ノバルティス バクシンズ アンド ダイアグノスティックス,インコーポレーテッド 抗菌活性を有するc12修飾エリスロマイシンマクロライドおよびケトライド
JP2006508643A (ja) 2002-07-01 2006-03-16 アーキオン ライフ サイエンシーズ エルエルシー ディー/ビー/エー バイオ−テクニカル リソーセズ ディビジョン グルコサミンおよびn−アセチルグルコサミン製造のためのプロセスおよび材料
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JP2006524702A (ja) * 2003-04-25 2006-11-02 カイロン コーポレイション ピリジル置換ケトライド抗体
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CA2703475A1 (en) * 2007-10-25 2009-04-30 Cempra Pharmaceuticals, Inc. Process for the preparation of macrolide antibacterial agents
US8796232B2 (en) * 2008-10-24 2014-08-05 Cempra Pharmaceuticals, Inc. Methods for treating resistant diseases using triazole containing macrolides
US9937194B1 (en) 2009-06-12 2018-04-10 Cempra Pharmaceuticals, Inc. Compounds and methods for treating inflammatory diseases
JP5914335B2 (ja) 2009-09-10 2016-05-11 センプラ ファーマシューティカルズ,インコーポレイテッド マラリア、結核、及びmac病の治療方法
CN103080122A (zh) 2010-03-22 2013-05-01 森普拉制药公司 大环内脂的结晶形式及其用途
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JP6042334B2 (ja) 2010-09-10 2016-12-14 センプラ ファーマシューティカルズ,インコーポレイテッド 疾患治療のための水素結合形成フルオロケトライド
CN104470527B (zh) 2012-03-27 2019-05-28 森普拉制药公司 用于施用大环内酯抗生素的肠胃外制剂
RU2015138796A (ru) 2013-03-14 2017-04-19 Семпра Фармасьютикалс, Инк. Способы и составы для лечения респираторных заболеваний
WO2014145210A1 (en) 2013-03-15 2014-09-18 Cempra Pharmaceuticals, Inc. Convergent processes for preparing macrolide antibacterial agents
JP6437523B2 (ja) 2013-04-04 2018-12-12 プレジデント アンド フェローズ オブ ハーバード カレッジ マクロライドならびにそれらの調製および使用の方法
US10633407B2 (en) * 2014-10-08 2020-04-28 President And Fellows Of Harvard College 14-membered ketolides and methods of their preparation and use
EP3273969A4 (en) 2015-03-25 2018-11-21 President and Fellows of Harvard College Macrolides with modified desosamine sugars and uses thereof
MD1222Z (ro) * 2017-05-31 2018-08-31 ИНСТИТУТ ЭЛЕКТРОННОЙ ИНЖЕНЕРИИ И НАНОТЕХНОЛОГИЙ "D. Ghitu" АНМ Procedeu de tratare a materialului săditor al florilor înainte de plantare
JP7199722B2 (ja) 2019-12-25 2023-01-06 旭精工株式会社 硬貨搬送振分機構及びそれを備えた硬貨識別搬送装置

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FR2692579B1 (fr) * 1992-06-19 1995-06-02 Roussel Uclaf Nouveaux dérivés de la picromycine, leur procédé de préparation et leur application comme médicaments.
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HRP930014A2 (en) * 1993-01-08 1994-08-31 Pliva Pharm & Chem Works 9-deoxo-9a-aza-11-deoxy-9a-homoeritromycin a 9a, 11-cyclic carbamates
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Also Published As

Publication number Publication date
YU21695A (sh) 1997-12-05
GB2288174A (en) 1995-10-11
GB9506856D0 (en) 1995-05-24
BG100150A (bg) 1996-06-28
PE2896A1 (es) 1996-02-12
SK284079B6 (sk) 2004-09-08
ES2189820T3 (es) 2003-07-16
LV11182B (en) 1997-04-20
NZ284498A (en) 1997-07-27
TNSN95026A1 (fr) 1996-02-06
IL112954A0 (en) 1995-06-29
NO954942L (no) 1996-02-07
JO1850B1 (en) 1995-12-27
HRP950217B1 (en) 2004-06-30
GEP19991836B (en) 1999-11-05
FI111264B (fi) 2003-06-30
RO115634B1 (ro) 2000-04-28
US5656607A (en) 1997-08-12
EE04498B1 (et) 2005-06-15
SK154695A3 (en) 1996-10-02
PT676409E (pt) 2003-08-29
KR100317148B1 (ko) 2002-06-22
JP3000023B2 (ja) 2000-01-17
HRP950217A2 (en) 1997-08-31
CZ322395A3 (en) 1996-08-14
IS1865B (is) 2003-05-02
EP0676409A1 (fr) 1995-10-11
US5760233A (en) 1998-06-02
CA2164638C (fr) 2003-12-30
DZ1869A1 (fr) 2002-02-17
CA2164638A1 (fr) 1995-10-19
JPH07278177A (ja) 1995-10-24
FI955913A0 (fi) 1995-12-08
CZ296005B6 (cs) 2005-12-14
CN1126997A (zh) 1996-07-17
FI955913A7 (fi) 1995-12-08
OA10200A (fr) 1996-12-18
SI0676409T1 (en) 2003-06-30
BG61916B1 (bg) 1998-09-30
SA97170757A (ar) 2005-12-03
MA23501A1 (fr) 1995-12-31
AP587A (en) 1997-04-29
ATE234853T1 (de) 2003-04-15
IL112954A (en) 2000-07-16
MD663G2 (ro) 1997-07-31
YU49221B (sh) 2004-11-25
NO954942D0 (no) 1995-12-06
AU2310795A (en) 1995-10-30
RU2141965C1 (ru) 1999-11-27
DE69529934T2 (de) 2003-09-04
MY114672A (en) 2002-12-31
CN1059445C (zh) 2000-12-13
SV1995000018A (es) 1997-10-24
BR9506147A (pt) 1996-04-16
HU215396B (hu) 1998-12-28
NO308361B1 (no) 2000-09-04
EP0676409B1 (fr) 2003-03-19
WO1995027720A1 (fr) 1995-10-19
LV11182A (lv) 1996-04-20
PL311871A1 (en) 1996-03-18
ZA952059B (en) 1996-03-13
HU9503505D0 (en) 1996-02-28
CO4370097A1 (es) 1996-10-07
AP9500743A0 (en) 1995-07-31
TW316908B (da) 1997-10-01
FR2718450A1 (fr) 1995-10-13
PL180837B1 (pl) 2001-04-30
DE69529934D1 (de) 2003-04-24
HUT73772A (en) 1996-09-30
AU684939B2 (en) 1998-01-08
EE9500080A (et) 1996-12-16
IS4309A (is) 1995-11-17
MD663F1 (ro) 1997-01-31
UA44705C2 (uk) 2002-03-15
FR2718450B1 (fr) 1997-01-10

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