DK0455783T3 - Anvendelse af nervonsyre og langkædede fedtsyrer til behandlingen af demyeliniserende sygdomme - Google Patents

Anvendelse af nervonsyre og langkædede fedtsyrer til behandlingen af demyeliniserende sygdomme

Info

Publication number: DK0455783T3
Authority: DK; Denmark
Prior art keywords: pct; treatment; fatty acids; chain fatty; acid
Prior art date: 1989-11-30

Application number

DK90917506.9T

Other languages

English (en)

Inventor

Keith Coupland

Nigel Alan Langley

Original Assignee

Croda Int Plc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-11-30

Filing date

1990-11-30

Publication date

1996-04-01

1989-11-30 Priority claimed from GB898927109A external-priority patent/GB8927109D0/en

1990-07-30 Priority claimed from GB909016660A external-priority patent/GB9016660D0/en

1990-11-30 Application filed by Croda Int Plc filed Critical Croda Int Plc

1996-04-01 Application granted granted Critical

1996-04-01 Publication of DK0455783T3 publication Critical patent/DK0455783T3/da

Links

208000016192 Demyelinating disease Diseases 0.000 title abstract 2
150000004668 long chain fatty acids Chemical class 0.000 title abstract 2
239000002253 acid Substances 0.000 title 1
239000000203 mixture Substances 0.000 abstract 2
DHEMVUXAYZGHFQ-QZOPMXJLSA-N (z)-tetracos-15-enoic acid Chemical compound CCCCCCCC\C=C/CCCCCCCCCCCCCC(O)=O.CCCCCCCC\C=C/CCCCCCCCCCCCCC(O)=O DHEMVUXAYZGHFQ-QZOPMXJLSA-N 0.000 abstract 1
DPUOLQHDNGRHBS-UHFFFAOYSA-N Brassidinsaeure Natural products CCCCCCCCC=CCCCCCCCCCCCC(O)=O DPUOLQHDNGRHBS-UHFFFAOYSA-N 0.000 abstract 1
URXZXNYJPAJJOQ-UHFFFAOYSA-N Erucic acid Natural products CCCCCCC=CCCCCCCCCCCCC(O)=O URXZXNYJPAJJOQ-UHFFFAOYSA-N 0.000 abstract 1
DPUOLQHDNGRHBS-KTKRTIGZSA-N erucic acid Chemical compound CCCCCCCC\C=C/CCCCCCCCCCCC(O)=O DPUOLQHDNGRHBS-KTKRTIGZSA-N 0.000 abstract 1
150000002148 esters Chemical class 0.000 abstract 1
201000006417 multiple sclerosis Diseases 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders

Landscapes

Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Epidemiology (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Emergency Medicine (AREA)
Immunology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Spinning Or Twisting Of Yarns (AREA)

DK90917506.9T 1989-11-30 1990-11-30 Anvendelse af nervonsyre og langkædede fedtsyrer til behandlingen af demyeliniserende sygdomme DK0455783T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB898927109A GB8927109D0 (en)	1989-11-30	1989-11-30	Pharmaceutical compositions
GB909016660A GB9016660D0 (en)	1990-07-30	1990-07-30	Pharmaceutical compositions

Publications (1)

Publication Number	Publication Date
DK0455783T3 true DK0455783T3 (da)	1996-04-01

Family

ID=26296282

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK90917506.9T DK0455783T3 (da)	1989-11-30	1990-11-30	Anvendelse af nervonsyre og langkædede fedtsyrer til behandlingen af demyeliniserende sygdomme

Country Status (10)

Country	Link
US (1)	US5194448A (da)
EP (1)	EP0455783B1 (da)
JP (1)	JPH07500566A (da)
AT (1)	ATE135208T1 (da)
DE (1)	DE69025922T2 (da)
DK (1)	DK0455783T3 (da)
ES (1)	ES2087165T3 (da)
GR (1)	GR3019315T3 (da)
NO (1)	NO912943L (da)
WO (1)	WO1991007955A1 (da)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5739109A (en) *	1988-12-16	1998-04-14	Advanced Immunit Inc.	Method of treating neuroinflammatory degenerative diseases
GB9416846D0 (en) *	1994-08-19	1994-10-12	Croda Int Plc	Lipid supplementation
GB9418420D0 (en) *	1994-09-13	1994-11-02	Mckeown Neil A	Composition for the treatment of an energy imbalance in ruminents
IL119661A0 (en) *	1996-11-20	1997-02-18	Yehuda Shlomo	Medical use of composition comprising fatty acids
DE19711777A1 (de) *	1997-03-21	1998-09-24	K D Pharma Gmbh	Bestandteil eines Hautpflegemittels
US6652866B1 (en) *	1997-10-14	2003-11-25	David W. Hertha	Method for treating diseases of fungal, yeast, and prion protein etiology
US6126986A (en) *	1999-02-23	2000-10-03	Westway Trading Corporation	Process for formulating a liquid animal feed ingredient containing sugar and neutralized carboxylic acid
GB9927629D0 (en) *	1999-11-24	2000-01-19	Croda Int Plc	Compounds
GB0112324D0 (en)	2001-05-21	2001-07-11	Croda Int Plc	Compounds
DE10148065A1 (de) *	2001-09-28	2003-04-17	Max Planck Gesellschaft	(Ester)-Lysolecithine in Liposomen
US6949586B2 (en) *	2002-02-11	2005-09-27	Council Of Scientific Research	Synergistic composition of trans-tetracos-15-enoic acid and Apocynin and method of treatment for hepatotoxicity
GB0604647D0 (en) *	2006-03-08	2006-04-19	Shchepinov Mikhail	Stabilized food supplements and their derivatives
ES2525345T3 (es) *	2006-03-24	2014-12-22	Metanomics Gmbh	Procedimiento de diagnóstico de diabetes de tipo II
US8269062B2 (en)	2006-11-21	2012-09-18	National Research Council Of Canada	Lunaria annua, Cardamine graeca and Teesdalia nudicaulis FAE genes and their use in producing nervonic and eicosenoic acids in seed oils
DK2493296T3 (da)	2009-10-30	2019-04-15	Retrotope Inc	Lindring af oxidative stresstilstande med pufa-derivater
KR102020579B1 (ko)	2011-04-26	2019-09-10	레트로토프 인코포레이티드	에너지 프로세싱 손상 장애 및 미토콘드리아 결함
WO2012148929A2 (en)	2011-04-26	2012-11-01	Retrotope, Inc.	Disorders implicating pufa oxidation
US10154983B2 (en)	2011-04-26	2018-12-18	Retrotope, Inc.	Neurodegenerative disorders and muscle diseases implicating PUFAs
US10058522B2 (en)	2011-04-26	2018-08-28	Retrotope, Inc.	Oxidative retinal diseases
WO2013071281A1 (en) *	2011-11-13	2013-05-16	Blanchette Rockefeller Neurosciences Institute	Esters of dcpla and methods of treatment using the same
WO2017091279A1 (en)	2015-11-23	2017-06-01	Retrotope, Inc.	Site-specific isotopic labeling of 1, 4-diene systems
CN105853996A (zh) *	2016-03-31	2016-08-17	山东健科生物技术有限公司	一种脑神经激活修复液
CN107441130A (zh) *	2017-08-04	2017-12-08	杨宇明	一种含蒜头果有效提取物的抗阿尔茨海默病的组合物及其应用
NO20181574A1 (en) *	2018-12-06	2020-06-08	Epax Norway As	Very long chain fatty acids
AU2020283321B2 (en) *	2019-05-31	2025-04-24	Epax Norway As	Very long chain fatty acids for treatment and alleviation of diseases
WO2021062383A1 (en) *	2019-09-27	2021-04-01	University Of Virginia Patent Foundation	Compositions and methods for preventing and/or reducing weight gain and associated conditions
EP4107163A4 (en)	2020-02-21	2024-06-19	Retrotope, Inc.	PROCESSES FOR ISOTOPIC MODIFICATION OF POLYUNSATURATED FATTY ACIDS AND THEIR DERIVATIVES
CN111735888B (zh) *	2020-08-14	2020-11-20	宝枫生物科技（北京）有限公司	用于诊断元宝枫籽油中神经酸起效的生物标记物及其应用
US12109194B2 (en)	2021-02-05	2024-10-08	Biojiva Llc	Synergistic combination therapy for treating ALS
US11491130B2 (en)	2021-02-05	2022-11-08	Retrotope, Inc.	Methods of treating amyotrophic lateral sclerosis

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ATE11014T1 (de) *	1981-07-14	1985-01-15	Efamol Limited	Pharmazeutische und diaetetische zusammensetzung zur erhoehung der serie-l-pg-produktion.
US4505933A (en) *	1982-02-01	1985-03-19	Hoerrmann Wilhelm	Fatty aldehydes in the treatment of Multiple Sclerosis
CH679119A5 (da) *	1988-05-13	1991-12-31	Sandoz Ag

1990
- 1990-11-30 DK DK90917506.9T patent/DK0455783T3/da active
- 1990-11-30 JP JP3500245A patent/JPH07500566A/ja active Pending
- 1990-11-30 US US07/730,916 patent/US5194448A/en not_active Expired - Lifetime
- 1990-11-30 EP EP90917506A patent/EP0455783B1/en not_active Expired - Lifetime
- 1990-11-30 AT AT90917506T patent/ATE135208T1/de not_active IP Right Cessation
- 1990-11-30 ES ES90917506T patent/ES2087165T3/es not_active Expired - Lifetime
- 1990-11-30 DE DE69025922T patent/DE69025922T2/de not_active Expired - Fee Related
- 1990-11-30 WO PCT/GB1990/001870 patent/WO1991007955A1/en not_active Ceased
1991
- 1991-07-29 NO NO91912943A patent/NO912943L/no unknown
1996
- 1996-03-14 GR GR960400520T patent/GR3019315T3/el unknown

Also Published As

Publication number	Publication date
WO1991007955A1 (en)	1991-06-13
ES2087165T3 (es)	1996-07-16
EP0455783B1 (en)	1996-03-13
GR3019315T3 (en)	1996-06-30
NO912943D0 (no)	1991-07-29
US5194448A (en)	1993-03-16
DE69025922T2 (de)	1996-10-02
NO912943L (no)	1991-07-29
JPH07500566A (ja)	1995-01-19
EP0455783A1 (en)	1991-11-13
DE69025922D1 (de)	1996-04-18
ATE135208T1 (de)	1996-03-15

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