DK0469985T3 - Fremgangsmåde til fremstilling af von Willebrand-faktor med meget høj renhed. - Google Patents

Fremgangsmåde til fremstilling af von Willebrand-faktor med meget høj renhed.

Info

Publication number
DK0469985T3
DK0469985T3 DK91402124.1T DK91402124T DK0469985T3 DK 0469985 T3 DK0469985 T3 DK 0469985T3 DK 91402124 T DK91402124 T DK 91402124T DK 0469985 T3 DK0469985 T3 DK 0469985T3
Authority
DK
Denmark
Prior art keywords
von willebrand
willebrand factor
factor
high purity
producing
Prior art date
Application number
DK91402124.1T
Other languages
English (en)
Inventor
Bernard Dazey
Mohamed Hamsany
Gerard Vezon
Original Assignee
Ass Daquitaine Pour Le Dev De
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9399373&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0469985(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ass Daquitaine Pour Le Dev De filed Critical Ass Daquitaine Pour Le Dev De
Application granted granted Critical
Publication of DK0469985T3 publication Critical patent/DK0469985T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK91402124.1T 1990-08-02 1991-07-30 Fremgangsmåde til fremstilling af von Willebrand-faktor med meget høj renhed. DK0469985T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9009917A FR2665449B1 (fr) 1990-08-02 1990-08-02 Procede de fabrication de facteur von willebrand ayant une tres haute purete, depourvu en majeure partie de facteur antihemophilique (fviiic), et facteur von willebrand ainsi obtenu, ainsi qu'une composition pharmaceutique le contenant.

Publications (1)

Publication Number Publication Date
DK0469985T3 true DK0469985T3 (da) 1997-10-20

Family

ID=9399373

Family Applications (1)

Application Number Title Priority Date Filing Date
DK91402124.1T DK0469985T3 (da) 1990-08-02 1991-07-30 Fremgangsmåde til fremstilling af von Willebrand-faktor med meget høj renhed.

Country Status (9)

Country Link
US (1) US5252710A (da)
EP (1) EP0469985B1 (da)
JP (1) JP2559645B2 (da)
AT (1) ATE152128T1 (da)
DE (2) DE69125764T2 (da)
DK (1) DK0469985T3 (da)
ES (1) ES2038095T3 (da)
FR (1) FR2665449B1 (da)
GR (1) GR3024115T3 (da)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5760183A (en) * 1989-02-17 1998-06-02 Association D'aquitaine Pour De Developpment De La Transfusion Sanguine Et Des Recherches Hematologiques Process for the manufacture of very high-purity antithaemophilic factor (FVIIIC), and von Willebrand factor, and pharmaceutical compositions containing same
US5610148A (en) * 1991-01-18 1997-03-11 University College London Macroscopically oriented cell adhesion protein for wound treatment
US5629287A (en) * 1991-01-18 1997-05-13 University College London Depot formulations
DE4435392B4 (de) * 1994-10-04 2008-02-07 Immuno Ag Verfahren zur Trennung von vWF in hochmolekularen vWF und niedermolekularen vWF
DE4435485C1 (de) * 1994-10-04 1996-03-21 Immuno Ag Verfahren zur Gewinnung von hochreinem von Willebrand-Faktor
US5659017A (en) * 1995-11-07 1997-08-19 Alpha Therapeutic Corporation Anion exchange process for the purification of Factor VIII
US6005077A (en) * 1995-11-10 1999-12-21 Immuno Aktiengesellschaft Use of von willebrand factor and pharmaceutical formulation
KR970060724A (ko) * 1996-01-16 1997-08-12 김광호 백업용 배터리 동작의 표시방법 및 그 감지회로
AT406867B (de) 1997-02-27 2000-10-25 Immuno Ag Verfahren zur gewinnung von hochreinem vwf oder faktor viii/vwf-komplex
AT405403B (de) 1997-02-27 1999-08-25 Immuno Ag Reinigung von von willebrand-faktor durch kationenaustauscherchromatographie
US6531577B1 (en) * 1997-12-15 2003-03-11 Hemasure Denmark A/S von Willebrand factor (vWF)-containing preparation, process for preparing vWF-containing preparations, and use of such preparations
CA2634663C (en) 1999-02-22 2009-08-25 University Of Connecticut Novel albumin-free factor viii formulations
JP4663837B2 (ja) * 1999-12-24 2011-04-06 一般財団法人化学及血清療法研究所 第▲ｖｉｉｉ▼因子を主成分とする血小板減少に伴う出血疾患の予防・治療用医薬組成物
EP1240900B1 (en) * 1999-12-24 2009-05-06 Juridical Foundation, The Chemo-Sero-Therapeutic Research Institute Factor viii or von willebrand factor for the treatment of hemorrhagic diseases associating thrombopathy
ATE460451T1 (de) * 2003-07-22 2010-03-15 Nektar Therapeutics Verfahren zur herstellung von funktionalisierten polymeren aus polymeralkoholen
FR2874216B1 (fr) * 2004-08-16 2006-11-03 Lab Francais Du Fractionnement Procede de preparation d'un concentre de facteur von willebrand (fvw) par voie chromatographique et concentre de fvw susceptible d'etre ainsi obtenu
US8568705B2 (en) 2005-07-18 2013-10-29 Nektar Therapeutics Method for preparing branched functionalized polymers using branched polyol cores
AU2009256093A1 (en) * 2008-06-04 2009-12-10 Bayer Healthcare Llc FVIII muteins for treatment of von Willebrand disease
EP2385825B1 (en) 2008-11-07 2018-10-10 University of Connecticut Factor viii formulations
IT1396528B1 (it) 2009-01-19 2012-12-14 Kedrion Spa Nuovo processo di purificazione altamente selettivo di due proteine plasmatiche: von willebrand factor (vwf) e fibronectina (fn).

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4170590A (en) * 1974-12-14 1979-10-09 Biotest-Serum-Institut Gmbh Ion exchanger treatment of citrate-stabilized plasma
US4508709A (en) * 1983-12-05 1985-04-02 Armour Pharmaceutical Company Process for purifying factor VIII:C
FR2570276B1 (fr) * 1984-09-18 1987-09-04 Immunotech Sa Procede d'obtention du complexe fviii/vwf a usage therapeutique et produits en resultant
JPS63108000A (ja) * 1986-05-15 1988-05-12 Green Cross Corp:The 第８因子の精製方法
US4774323A (en) * 1987-06-29 1988-09-27 Rorer Pharmaceutical Corporation Purification of von Willebrand Factor solutions using gel permeation chromatography
NL8701915A (nl) * 1987-08-14 1989-03-01 Waander Riethorst Adsorbensmateriaal en toepassing daarvan voor het isoleren van stollingsfaktoren.
FR2632309B1 (fr) * 1988-06-07 1990-08-24 Lille Transfusion Sanguine Procede de purification par voie chromatographique de proteines, notamment de facteur viii, et les produits obtenus
FR2644064B1 (fr) * 1989-02-17 1994-05-27 Aquitaine Dev Transf Sanguine Procede de fabrication du facteur antihemophilique fviiic ayant une tres haute purete et facteur antihemophilique fviiic ainsi obtenu, ainsi que composition pharmaceutique le contenant
FR2650393A1 (fr) * 1989-07-28 1991-02-01 Herault Ctre Rgl Transfusion S Methode de purification du facteur vii (f viii) par chromatographie echangeuse d'ions

Also Published As

Publication number Publication date
FR2665449B1 (fr) 1995-04-14
ES2038095T3 (es) 1997-09-16
ATE152128T1 (de) 1997-05-15
EP0469985A1 (en) 1992-02-05
EP0469985B1 (en) 1997-04-23
DE69125764T2 (de) 1997-11-13
JPH04234400A (ja) 1992-08-24
US5252710A (en) 1993-10-12
GR3024115T3 (en) 1997-10-31
DE69125764D1 (de) 1997-05-28
FR2665449A1 (fr) 1992-02-07
JP2559645B2 (ja) 1996-12-04
DE469985T1 (de) 1992-10-15
ES2038095T1 (es) 1993-07-16

Similar Documents

Publication Publication Date Title
GR3024115T3 (en) Process for manufacturing von Willebrand factor having a very high purity
DK0658164T3 (da) Fremgangsmåde til chromatografisk oprensning og adskillelse af nukleinsyreblandinger
UA11061A (uk) Спосіб розділеhhя білків крові
FR2651437B1 (da)
ATE515950T1 (de) Fraktionierung von proteinhaltigen mischungen
EP0144957A3 (en) Process for purifying factor viii:c
DE69326227D1 (de) Verfahren zur Isolation von hoch angereicherten Faktoren IX, X und II vom Prothrombin komplex oder menschlichem Plasma
DK0646594T3 (da) Fremgangsmåde til rensning af proteiner
ATE91152T1 (de) Gereinigte protein a-zusammensetzungen und verfahren zu ihrer herstellung.
DE59309220D1 (de) Sorption von organischen Verbindungen aus Gasen
CA2335811A1 (en) Method and apparatus for the production of purified plasma proteins
HU9301038D0 (en) Method for producing virus-safe vii factor of high purity
EP0004465A3 (en) Method of regenerating adsorbents
CA2223702A1 (en) Therapeutic fragments of von willebrand factor
ES2042027T3 (es) Procedimiento de recuperacion de acido citrico a partir de un licor que lo contiene.
ES2040684T3 (es) Metodo para la regeneracion de un adsorbente de tanino.
SE8505451D0 (sv) Purification of l-phenylalanine
DK0383645T3 (da) Fremgangsmåde til fremstilling af antihæmofilifaktor (FVIIIc) med meget høj renhed
GR3021419T3 (en) Process for preparing highly purified fibrinogen
DK1015568T3 (da) Fremgangsmåde til produktion af rDSPAalfa1
EP0711786A3 (da)
SU1701350A1 (ru) Способ разделени криптона и ксенона
GEP19940019B (en) Device for Production of Isotopes of Oxygen-18, Oxygen-17 and Nitrogen-15
PL265427A1 (en) Method of purifying gaseous mixtures by adsorption processes and adsorber therefor
NZ326494A (en) Production of an immunoglobulin enriched fraction from whey protein solutions using a cation exchanger