DK0472657T3 - Fremgangsmåde og middel til behandling af trombose i et pattedyr - Google Patents

Fremgangsmåde og middel til behandling af trombose i et pattedyr

Info

Publication number
DK0472657T3
DK0472657T3 DK90909024.3T DK90909024T DK0472657T3 DK 0472657 T3 DK0472657 T3 DK 0472657T3 DK 90909024 T DK90909024 T DK 90909024T DK 0472657 T3 DK0472657 T3 DK 0472657T3
Authority
DK
Denmark
Prior art keywords
plasminogen activator
mammal
core
composition
controlled release
Prior art date
Application number
DK90909024.3T
Other languages
English (en)
Inventor
Edgar O Orear Iii
Philip D Nguyen
Arthur E Johnson
Eugene S Patterson
Thomas L Whitsett
Original Assignee
Res Corp Technologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Res Corp Technologies Inc filed Critical Res Corp Technologies Inc
Application granted granted Critical
Publication of DK0472657T3 publication Critical patent/DK0472657T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/164—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • A61K38/166—Streptokinase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Dispersion Chemistry (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK90909024.3T 1989-05-17 1990-05-15 Fremgangsmåde og middel til behandling af trombose i et pattedyr DK0472657T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US35369389A 1989-05-17 1989-05-17

Publications (1)

Publication Number Publication Date
DK0472657T3 true DK0472657T3 (da) 1996-06-17

Family

ID=23390149

Family Applications (1)

Application Number Title Priority Date Filing Date
DK90909024.3T DK0472657T3 (da) 1989-05-17 1990-05-15 Fremgangsmåde og middel til behandling af trombose i et pattedyr

Country Status (10)

Country Link
US (1) US5503850A (da)
EP (1) EP0472657B1 (da)
JP (1) JPH05501855A (da)
AT (1) ATE135200T1 (da)
AU (1) AU635541B2 (da)
CA (1) CA2016949C (da)
DE (1) DE69025934T2 (da)
DK (1) DK0472657T3 (da)
ES (1) ES2085352T3 (da)
WO (1) WO1990014078A1 (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6461640B1 (en) 1995-12-08 2002-10-08 Board Of Regents, The University Of Texas System Local delivery of fibrinolysis enhancing agents
KR19980067002A (ko) * 1997-01-30 1998-10-15 김종국 스트렙토키나제를 리포좀에 봉입하여 얻는 혈중체류성 혈전용해제 및 그 제조방법
US6586011B2 (en) * 1999-06-10 2003-07-01 Southpac Trust International, Inc. Microencapsulated plasminogen activators
SI1438065T1 (sl) * 2001-10-01 2013-03-29 Martizyme Pharma Corporation Uporaba kolagenaze za olajšanje prehoda vodilne žice skozi kronične arterijske okluzije
WO2004047800A2 (en) * 2002-11-26 2004-06-10 Gilead Sciences, Inc. Method of drug loading in liposomes by gradient
US9814672B2 (en) * 2007-03-09 2017-11-14 Susan T. Laing Echogenic vehicle for clinical delivery of plasminogen activator and other fibrin-binding therapeutics to thrombi

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH588887A5 (da) * 1974-07-19 1977-06-15 Battelle Memorial Institute
US4235871A (en) * 1978-02-24 1980-11-25 Papahadjopoulos Demetrios P Method of encapsulating biologically active materials in lipid vesicles
JPS54147916A (en) * 1978-05-12 1979-11-19 Sumitomo Chem Co Ltd Preparation of urokinase injection
EP0028489B1 (en) * 1979-11-05 1983-10-05 Beecham Group Plc Enzyme derivatives, and their preparation
JPS574913A (en) * 1980-06-11 1982-01-11 Green Cross Corp:The Urokinase preparation for oral administration
US4640835A (en) * 1981-10-30 1987-02-03 Nippon Chemiphar Company, Ltd. Plasminogen activator derivatives
JPS58222410A (ja) * 1982-06-19 1983-12-24 Mitsubishi Electric Corp ２進デ−タの記録再生装置
JPS59196824A (ja) * 1983-04-21 1984-11-08 Kowa Co 吸着防止剤
JPS59222410A (ja) * 1983-06-01 1984-12-14 Terumo Corp 薬物保持リポソ−ム製剤
JPS60215633A (ja) * 1984-04-11 1985-10-29 Terumo Corp 腸管吸収性ウロキナ−ゼリポソ−ム組成物
US4615885A (en) * 1983-11-01 1986-10-07 Terumo Kabushiki Kaisha Pharmaceutical composition containing urokinase
JPS60155109A (ja) * 1984-01-23 1985-08-15 Terumo Corp リポソ−ム製剤
DE3584902D1 (de) * 1984-02-29 1992-01-30 Asahi Chemical Ind Waessrige loesung eines darin in erhoehter konzentration aufgeloesten gewebe-plasminogen-aktivators und herstellungsverfahren.
JPS60231609A (ja) * 1984-04-28 1985-11-18 Terumo Corp リポソ−ム製剤
JPS61353A (ja) * 1984-06-13 1986-01-06 テルモ株式会社 薬剤投与装置
JPS6176414A (ja) * 1984-09-21 1986-04-18 Shionogi & Co Ltd リポソーム製剤の製法
NL8503097A (nl) * 1985-11-11 1987-06-01 Leuven Res & Dev Vzw Geneesmiddel met thrombolytische werking.
EP0227400B1 (en) * 1985-12-16 1991-12-04 Ethicon, Inc. Inhibition of post-surgical adhesion formation by the topical administration of tissue plasminogen activator
JPH0610139B2 (ja) * 1986-05-15 1994-02-09 エモリ ユニバーシティ 繊維素溶解性合成物混合物及び血管内の血餅溶解用薬剤
EP0247497B1 (en) * 1986-05-20 1992-03-04 Wako Pure Chemical Industries, Ltd. Novel functionalized liposomes and a process for production thereof
JPH01115164A (ja) * 1987-10-28 1989-05-08 Oki Electric Ind Co Ltd 半導体装置
US5000887A (en) * 1988-05-17 1991-03-19 Liposome Technology, Inc. Preparation of uniform-size liposomes

Also Published As

Publication number Publication date
EP0472657A1 (en) 1992-03-04
AU5810590A (en) 1990-12-18
DE69025934D1 (de) 1996-04-18
JPH05501855A (ja) 1993-04-08
ES2085352T3 (es) 1996-06-01
DE69025934T2 (de) 1996-09-19
CA2016949A1 (en) 1990-11-17
EP0472657B1 (en) 1996-03-13
ATE135200T1 (de) 1996-03-15
WO1990014078A1 (en) 1990-11-29
CA2016949C (en) 1996-12-10
AU635541B2 (en) 1993-03-25
EP0472657A4 (en) 1992-07-08
US5503850A (en) 1996-04-02

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