DK0483704T3 - Fremgangsmåde til fremstilling af et radiofarmaceutisk præparat - Google Patents

Fremgangsmåde til fremstilling af et radiofarmaceutisk præparat

Info

Publication number: DK0483704T3
Authority: DK; Denmark
Prior art keywords: water; radiopharmaceutical composition; nhch2co; reducing agent; preparation
Prior art date: 1990-10-31

Application number

DK91118291.3T

Other languages

English (en)

Inventor

Susumu Kondo

Sakae Okano

Makoto Azuma

Original Assignee

Nihon Mediphysics Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-10-31

Filing date

1991-10-26

Publication date

1995-05-22

1991-10-26 Application filed by Nihon Mediphysics Co Ltd filed Critical Nihon Mediphysics Co Ltd

1995-05-22 Application granted granted Critical

1995-05-22 Publication of DK0483704T3 publication Critical patent/DK0483704T3/da

Links

238000000034 method Methods 0.000 title abstract 2
239000000203 mixture Substances 0.000 title abstract 2
239000012217 radiopharmaceutical Substances 0.000 title abstract 2
229940121896 radiopharmaceutical Drugs 0.000 title abstract 2
230000002799 radiopharmaceutical effect Effects 0.000 title abstract 2
RXACEEPNTRHYBQ-UHFFFAOYSA-N 2-[[2-[[2-[(2-sulfanylacetyl)amino]acetyl]amino]acetyl]amino]acetic acid Chemical compound OC(=O)CNC(=O)CNC(=O)CNC(=O)CS RXACEEPNTRHYBQ-UHFFFAOYSA-N 0.000 abstract 2
239000003638 chemical reducing agent Substances 0.000 abstract 2
238000002372 labelling Methods 0.000 abstract 2
206010073306 Exposure to radiation Diseases 0.000 abstract 1
238000010438 heat treatment Methods 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1
239000011369 resultant mixture Substances 0.000 abstract 1
239000003381 stabilizer Substances 0.000 abstract 1
229940056501 technetium 99m Drugs 0.000 abstract 1
-1 technetium 99m chelate complex Chemical class 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2123/00—Preparations for testing in vivo

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Epidemiology (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Optics & Photonics (AREA)
Pharmacology & Pharmacy (AREA)
Physics & Mathematics (AREA)
Animal Behavior & Ethology (AREA)
Chemical & Material Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Saccharide Compounds (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

DK91118291.3T 1990-10-31 1991-10-26 Fremgangsmåde til fremstilling af et radiofarmaceutisk præparat DK0483704T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP2296563A JP2860157B2 (ja)	1990-10-31	1990-10-31	腎機能測定用の既放射能標識テクネチウムキレート注射剤の製造方法

Publications (1)

Publication Number	Publication Date
DK0483704T3 true DK0483704T3 (da)	1995-05-22

Family

ID=17835168

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK91118291.3T DK0483704T3 (da)	1990-10-31	1991-10-26	Fremgangsmåde til fremstilling af et radiofarmaceutisk præparat

Country Status (10)

Country	Link
US (1)	US5245018A (da)
EP (1)	EP0483704B1 (da)
JP (1)	JP2860157B2 (da)
KR (1)	KR0175305B1 (da)
AT (1)	ATE121632T1 (da)
AU (1)	AU638363B2 (da)
CA (1)	CA2054263C (da)
DE (1)	DE69109235T2 (da)
DK (1)	DK0483704T3 (da)
ES (1)	ES2074200T3 (da)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5208007A (en) *	1988-11-22	1993-05-04	Board Of Regents Of The University Of Oklahoma	Isotopic tracer composition and method for making and using same
US5849261A (en) *	1991-02-08	1998-12-15	Diatide, Inc.	Radiolabeled vasoactive intestinal peptides for diagnosis and therapy
US5443815A (en) *	1991-11-27	1995-08-22	Diatech, Inc.	Technetium-99m labeled peptides for imaging
US7238340B1 (en)	1991-11-27	2007-07-03	Cis Bio International	Monoamine, diamide, thiol-containing metal chelating agents
US5783170A (en) *	1991-11-27	1998-07-21	Diatide, Inc.	Peptide-metal chelate conjugates
CN1087955C (zh) *	1994-05-02	2002-07-24	迪亚太德公司	锝－99m标记的成像剂
IL113610A0 (en) *	1994-06-03	1995-08-31	Immunomedics Inc	A method of radiolabeling a protein, radiolabeled proteins prepared thereby and diagnostic kits containing the same
US5746996A (en) *	1994-06-03	1998-05-05	Immunomedics, Inc.	Thiolation of peptides for radionuclide-based radiodetection and radiotherapy
US5986074A (en) *	1996-05-06	1999-11-16	Emory University	Metal chelates as pharmaceutical imaging agents, processes of making such and uses thereof
US5924973A (en)	1996-09-26	1999-07-20	The Trustees Of Columbia University In The City Of New York	Method of treating a disease process in a luminal structure
JP5139678B2 (ja) *	2003-07-24	2013-02-06	ブラッコ・イメージング・ソシエタ・ペル・アチオニ	安定な放射性医薬品組成物およびその製法
WO2005079864A2 (en) *	2004-02-13	2005-09-01	Mallinckrodt Inc.	Improvement in the ligand protection for mercaptoacetyl triglycine
GB0427392D0 (en)	2004-12-15	2005-01-19	Amersham Plc	Stabilised 99mTc compositions
WO2008115337A1 (en) *	2007-03-19	2008-09-25	Mallinckrodt Inc.	Sulfur-protected mercaptoacetylglycylglycylglycine
BRPI0800492B8 (pt) *	2008-01-31	2021-05-25	Univ Minas Gerais	radiofármaco e sua composição farmacêutica para tratamento e diagnóstico de câncer
GB201402132D0 (en) *	2014-02-07	2014-03-26	South African Nuclear Energy	A method of producing ethylenedicysteine deoxyglucosamine (ECDG) or a salt thereof and its application in a kit
US9850183B2 (en)	2014-06-27	2017-12-26	Reiley Pharmaceuticals, Inc.	Conjugates derived from non-steroidal anti-inflammatory drugs and methods of use thereof in imaging
EP3242688B1 (en)	2015-01-09	2020-01-29	Reiley Pharmaceuticals, Inc.	Cox-2-targeting, platinum-containing conjugates and their use in the treatment of tumors and cancers

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3171920D1 (en) *	1981-09-16	1985-09-26	Nihon Mediphysics Co Ltd	Radioactive diagnostic agent and its preparation
JPS5896031A (ja) *	1981-12-03	1983-06-07	Nippon Mejifuijitsukusu Kk	放射性診断剤およびその製造用組成物
US4510125A (en) *	1982-12-08	1985-04-09	Mallinckrodt, Inc.	Process for making lyophilized radiographic imaging kit
US4638051A (en) *	1984-04-30	1987-01-20	The Johns Hopkins University	Brain imaging radiopharmaceuticals
US4980147A (en) *	1984-06-25	1990-12-25	University Of Utah Research Foundation	Radiolabeled technetium chelates for use in renal function determinations
ATE52516T1 (de) *	1986-05-28	1990-05-15	Mallinckrodt Inc	Technetiumchelate fuer die bestimmung der nierenfunktion.
US4883862A (en) *	1988-04-13	1989-11-28	Albert Einstein College Of Medicine - Of Yeshiva University	Mercaptosuccinyl glycyl-glycyl-glycine a complex thereof with Tc-99m, and methods of making the same
US4925650A (en) *	1988-11-16	1990-05-15	Mallinckrodt, Inc.	Technetium -99m complex for examining the renal function
DE122005000028I2 (de) *	1989-10-30	2007-08-16	Rotop Pharmaka Ag	Kit (nichtradioaktive Vorstufe) zur Herstellung einer enantiomeren Form des Nierenfunktionsdiagnostikums Technetium-99m-Mercaptoacetyltriglycin (99m-Tc-MAG-3) und Verfahren zur Herstellung des Kits
WO1991016076A1 (en) *	1990-04-17	1991-10-31	Mallinckrodt Medical, Inc.	Method and kit for preparing technetium-99m complexes

1990
- 1990-10-31 JP JP2296563A patent/JP2860157B2/ja not_active Expired - Lifetime
1991
- 1991-10-25 CA CA002054263A patent/CA2054263C/en not_active Expired - Fee Related
- 1991-10-26 DK DK91118291.3T patent/DK0483704T3/da active
- 1991-10-26 ES ES91118291T patent/ES2074200T3/es not_active Expired - Lifetime
- 1991-10-26 AT AT91118291T patent/ATE121632T1/de not_active IP Right Cessation
- 1991-10-26 DE DE69109235T patent/DE69109235T2/de not_active Expired - Fee Related
- 1991-10-26 EP EP91118291A patent/EP0483704B1/en not_active Expired - Lifetime
- 1991-10-29 US US07/783,776 patent/US5245018A/en not_active Expired - Lifetime
- 1991-10-30 AU AU86909/91A patent/AU638363B2/en not_active Ceased
- 1991-10-31 KR KR1019910019246A patent/KR0175305B1/ko not_active Expired - Fee Related

Also Published As

Publication number	Publication date
AU638363B2 (en)	1993-06-24
DE69109235T2 (de)	1995-09-28
EP0483704B1 (en)	1995-04-26
EP0483704A1 (en)	1992-05-06
DE69109235D1 (de)	1995-06-01
KR0175305B1 (ko)	1999-02-18
CA2054263A1 (en)	1992-05-01
ATE121632T1 (de)	1995-05-15
US5245018A (en)	1993-09-14
JP2860157B2 (ja)	1999-02-24
CA2054263C (en)	2001-05-29
KR920007639A (ko)	1992-05-27
ES2074200T3 (es)	1995-09-01
JPH04169540A (ja)	1992-06-17
AU8690991A (en)	1992-05-07

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