DK0509752T3 - Oftalmiske præparater, der omfatter kombinationer af en carbonathydrolyaseinhibitor og en beta-adrenerg antagonist - Google Patents

Oftalmiske præparater, der omfatter kombinationer af en carbonathydrolyaseinhibitor og en beta-adrenerg antagonist

Info

Publication number: DK0509752T3
Authority: DK; Denmark
Prior art keywords: beta; combinations; inhibitor; hydrolyase; carbonate
Prior art date: 1991-04-17

Application number

DK92303330T

Other languages

Danish (da)

English (en)

Inventor

John J Baldwin

Original Assignee

Merck & Co Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-04-17

Filing date

1992-04-14

Publication date

1999-12-06

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27103852&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0509752(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1992-04-14 Application filed by Merck & Co Inc filed Critical Merck & Co Inc

1999-12-06 Application granted granted Critical

1999-12-06 Publication of DK0509752T3 publication Critical patent/DK0509752T3/da

Links

239000002876 beta blocker Substances 0.000 title abstract 3
102000003846 Carbonic anhydrases Human genes 0.000 title 1
108090000209 Carbonic anhydrases Proteins 0.000 title 1
239000004095 hydrolyase inhibitor Substances 0.000 title 1
238000002360 preparation method Methods 0.000 title 1
229940122072 Carbonic anhydrase inhibitor Drugs 0.000 abstract 1
206010030043 Ocular hypertension Diseases 0.000 abstract 1
239000003489 carbonate dehydratase inhibitor Substances 0.000 abstract 1
230000000699 topical effect Effects 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Ophthalmology & Optometry (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicinal Preparation (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

DK92303330T 1991-04-17 1992-04-14 Oftalmiske præparater, der omfatter kombinationer af en carbonathydrolyaseinhibitor og en beta-adrenerg antagonist DK0509752T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US68671891A	1991-04-17	1991-04-17
US83491392A	1992-02-13	1992-02-13

Publications (1)

Publication Number	Publication Date
DK0509752T3 true DK0509752T3 (da)	1999-12-06

Family

ID=27103852

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK92303330T DK0509752T3 (da)	1991-04-17	1992-04-14	Oftalmiske præparater, der omfatter kombinationer af en carbonathydrolyaseinhibitor og en beta-adrenerg antagonist

Country Status (24)

Country	Link
EP (1)	EP0509752B1 (fr)
JP (1)	JP2527513B2 (fr)
KR (1)	KR920019348A (fr)
CN (1)	CN1073421C (fr)
AT (1)	ATE182787T1 (fr)
AU (1)	AU648659C (fr)
CA (1)	CA2065965C (fr)
CH (1)	CH0509752H1 (fr)
CY (1)	CY2146B1 (fr)
CZ (1)	CZ285129B6 (fr)
DE (3)	DE69229688C5 (fr)
DK (1)	DK0509752T3 (fr)
ES (1)	ES2133304T3 (fr)
GR (1)	GR3031467T3 (fr)
IE (1)	IE921240A1 (fr)
IL (1)	IL101537A (fr)
LU (1)	LU90506I2 (fr)
MX (1)	MX9201785A (fr)
NL (1)	NL990041I2 (fr)
NO (1)	NO306196B1 (fr)
RO (1)	RO113612B1 (fr)
SK (1)	SK282039B6 (fr)
WO (1)	WO1992018124A1 (fr)
YU (1)	YU39392A (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5932572A (en) *	1992-02-21	1999-08-03	Alcon Laboratories, Inc.	Topical anti-glaucoma compositions
ES2118941T3 (es) *	1992-02-21	1998-10-01	Alcon Lab Inc	Composiciones antiglaucoma topicas que comprenden inhibidores de anhidrasa carbonica y bloqueantes beta.
US6071904A (en) *	1996-12-11	2000-06-06	Alcon Laboratories, Inc.	Process for manufacturing ophthalmic suspensions
FI981473A7 (fi) *	1998-06-25	1999-12-26	Orion Yhtymae Oyj	Menetelmä pulmonaalihypertension hoitamiseksi
TWI298257B (en)	2001-05-31	2008-07-01	Allergan Inc	Hypotensive lipid and timolol compositions and methods of using same
CN100345594C (zh) *	2004-01-19	2007-10-31	无锡杰西医药科技有限公司	乙酰唑胺滴眼液
US8211450B2 (en) *	2010-05-05	2012-07-03	Senju Usa, Inc.	Ophthalmic composition
US9061034B2 (en)	2010-07-29	2015-06-23	Allergan, Inc.	Preservative free bimatoprost and timolol solutions
RU2624534C2 (ru)	2010-07-29	2017-07-04	Аллерган, Инк.	Растворы биматопроста и тимолола, не содержащие консервантов
JP5893204B1 (ja) *	2015-02-23	2016-03-23	参天製薬株式会社	防腐効果のある医薬の組合せ
JP6132968B1 (ja) *	2016-01-29	2017-05-24	参天製薬株式会社	ドルゾラミド、高分子およびホウ酸を含有する医薬組成物

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4863922A (en) *	1984-12-12	1989-09-05	Merck & Co., Inc.	Substituted aromatic sulfonamides as antiglaucoma agents, compositions and use

1992
- 1992-04-09 IL IL101537A patent/IL101537A/xx not_active IP Right Cessation
- 1992-04-09 RO RO93-01388A patent/RO113612B1/ro unknown
- 1992-04-09 CZ CZ932098A patent/CZ285129B6/cs not_active IP Right Cessation
- 1992-04-09 SK SK1103-93A patent/SK282039B6/sk not_active IP Right Cessation
- 1992-04-09 WO PCT/US1992/002903 patent/WO1992018124A1/fr not_active Ceased
- 1992-04-14 DE DE69229688A patent/DE69229688C5/de not_active Expired - Lifetime
- 1992-04-14 DE DE2000175002 patent/DE10075002I2/de active Active
- 1992-04-14 EP EP92303330A patent/EP0509752B1/fr not_active Expired - Lifetime
- 1992-04-14 CA CA002065965A patent/CA2065965C/fr not_active Expired - Lifetime
- 1992-04-14 AT AT92303330T patent/ATE182787T1/de active
- 1992-04-14 DE DE69229688T patent/DE69229688T4/de not_active Expired - Lifetime
- 1992-04-14 CH CH92303330T patent/CH0509752H1/fr unknown
- 1992-04-14 DK DK92303330T patent/DK0509752T3/da active
- 1992-04-14 ES ES92303330T patent/ES2133304T3/es not_active Expired - Lifetime
- 1992-04-15 MX MX9201785A patent/MX9201785A/es unknown
- 1992-04-15 YU YU39392A patent/YU39392A/sh unknown
- 1992-04-16 AU AU14979/92A patent/AU648659C/en not_active Expired
- 1992-04-16 IE IE124092A patent/IE921240A1/en not_active IP Right Cessation
- 1992-04-16 KR KR1019920006335A patent/KR920019348A/ko not_active Ceased
- 1992-04-16 CN CN92103682A patent/CN1073421C/zh not_active Expired - Lifetime
- 1992-04-17 JP JP4097956A patent/JP2527513B2/ja not_active Expired - Lifetime
1993
- 1993-10-15 NO NO933714A patent/NO306196B1/no not_active IP Right Cessation
1999
- 1999-10-08 GR GR990402558T patent/GR3031467T3/el unknown
- 1999-12-01 NL NL990041C patent/NL990041I2/nl unknown
- 1999-12-29 CY CY9900045A patent/CY2146B1/xx unknown
2000
- 2000-01-19 LU LU90506C patent/LU90506I2/fr unknown

Also Published As

Publication number	Publication date
IL101537A (en)	1997-11-20
DE10075002I2 (de)	2004-07-01
NO933714D0 (no)	1993-10-15
JPH05117167A (ja)	1993-05-14
CN1073421C (zh)	2001-10-24
WO1992018124A1 (fr)	1992-10-29
IE921240A1 (en)	1992-10-21
CZ285129B6 (cs)	1999-05-12
GR3031467T3 (en)	2000-01-31
DE69229688C5 (de)	2010-10-21
MX9201785A (es)	1992-10-01
HK1009251A1 (en)	1999-05-28
DE69229688T2 (de)	2000-02-24
EP0509752A2 (fr)	1992-10-21
AU648659B2 (en)	1994-04-28
CA2065965A1 (fr)	1992-10-18
NO306196B1 (no)	1999-10-04
IL101537A0 (en)	1992-12-30
AU648659C (en)	2008-02-14
KR920019348A (ko)	1992-11-19
RO113612B1 (ro)	1998-09-30
ATE182787T1 (de)	1999-08-15
SK110393A3 (en)	1994-02-02
NO933714L (no)	1993-10-15
CA2065965C (fr)	1998-06-16
NL990041I1 (nl)	2000-02-01
EP0509752A3 (en)	1993-03-03
CZ209893A3 (en)	1994-06-15
JP2527513B2 (ja)	1996-08-28
DE69229688T4 (de)	2010-08-19
CN1066781A (zh)	1992-12-09
LU90506I2 (fr)	2000-03-28
ES2133304T3 (es)	1999-09-16
YU39392A (sh)	1995-12-04
CY2146B1 (en)	2002-06-21
AU1497992A (en)	1992-10-22
CH0509752H1 (fr)	2012-11-30
EP0509752B1 (fr)	1999-08-04
DE69229688D1 (de)	1999-09-09
SK282039B6 (sk)	2001-10-08
DE10075002I1 (de)	2000-03-30
NL990041I2 (nl)	2000-04-03

Publication	Publication Date	Title
EP0594602A4 (fr)	1993-06-16	Inhibiteurs d'anhydrase carbonique du thiadiazole sulfonamide a activite topique oculaire.
FI921924A7 (fi)	1992-11-09	Portabel koldioxidmonitor
TR22827A (tr)	1988-08-17	N-(4-fenoksi-2,6-diizopropilfenil)-n'-ters,butil tio,uerenin beyaz sineklerle muecadelede kullanilmasi
DE19575017I2 (de)	2008-11-20	Substituierte aromatische Sulfonamide als Mittel gegen Glaukom.
IT8553000U1 (it)	1986-08-18	Dispositivo di protezione del capo per attivita' sportive, particolarmente per sci agonistico.
DE69418947D1 (de)	1999-07-15	Stilbenderivate und analoga sowie deren anwendung
ATE133663T1 (de)	1996-02-15	Antiglancoma-zusammensetzungen enthaltend 3- arylcarbonyl-1-aminoalkyl-1h-indol
DK0721457T3 (da)	1999-11-08	2',5'-Oligoadenylat-2',3'-cyclophosphater og 2',5'-oligo-adenylater med antipapillomavirusaktivitet
GR3031467T3 (en)	2000-01-31	Ophthalmic compositions comprising combinations of a carbonic anhydrase inhibitor and a beta-adrenergic antagonist
DK0679717T3 (da)	2000-03-13	Opløselig interferon-receptor og fremstilling og anvendelse heraf
DE69329945D1 (de)	2001-03-29	Polarisierendes element, optisches element und optischer kopf
ITMI911671A1 (it)	1992-12-19	Testa di avvitatura spezzabile e monouso, a coppia di avvitatura predeterminata.
FI961977A0 (fi)	1996-05-09	N-substituoidut atsabisykloalkaanijohdannaiset, niiden valmistus ja käyttö
NO991581D0 (no)	1999-03-30	N-(benzotiazol-2-yl)piperidin-1-etanaminderivater, deres fremstilling og anvendelse i terapeutiske midler
DK0458587T3 (da)	1993-08-23	Behandling af okulær hypertension med en synergistisk kombination til ophthalmisk anvendelse
DK223287A (da)	1987-11-03	Heterocycliske sulfonamider og deres anvendelse som herbicider
FI970165L (fi)	1997-03-14	(S)-atenosyyli-L-metioniinin (SAMe) ja sen fysiologisesti hyväksyttävien suolojen käyttö tilapäisen fokaalisen iskemian aiheuttamien reperfuusiovammojen hoitamiseksi
DK435089A (da)	1990-03-03	Anvendelse af zofenopril til behandling af rheumatoid arthritis
KR930011853U (ko)	1993-06-25	전기 광학 주사 장치와, 주사 장치에 사용하기 위한 힌지 요소, 및 주사 장치를 포함한 광학 플레이어
NO942322D0 (no)	1994-06-17	Nye 3-halogen-5-halogenmetyl-2-oksazolidinoner og deres anvendelse som mikrobicider
NO914779L (no)	1992-06-09	Adenosin-forbindelse i ny krystallform, fremgangsmaate fordens fremstilling og terapeutisk anvendelse derav
ITMI910913U1 (it)	1993-04-21	Portaombrelli portatile, in particolare per l'utilizzo all'interno di autovetture
KR940021123U (ko)	1994-09-24	두 편광자의 교차를 이용한 작업용 보안경
NO871946D0 (no)	1987-05-12	Solskjerm i ny konstruksjon med alternative bruksomraader.
DK617689D0 (da)	1989-12-07	(d)-6-fluor-2,3-dihydro-2',5'-dioxo-spirooe4h-1-benzopyran-4,4'-imidazolidinaa-2-carboxamidderivater, fremgangsmaade til deres fremstilling og deres anvendelse